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  1. Last 7 days
  2. www.nature.com www.nature.com
    Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing
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    1. scibot 21 Dec 2024
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      DOI: 10.1038/s41586-024-08348-2

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    nature.com/articles/s41586-024-08348-2
  3. www.sciencedirect.com www.sciencedirect.com
    The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation
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    1. scibot 21 Dec 2024
      RRID:AB_10860252

      DOI: 10.1016/j.celrep.2024.115101

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    sciencedirect.com/science/article/pii/S2211124724014529
  4. Jan 2024
  5. www.sciencedirect.com www.sciencedirect.com
    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
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    1. scibot 11 Jan 2024
      RRID:AB_10860252

      DOI: 10.1016/j.jbc.2024.105641

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    sciencedirect.com/science/article/pii/S0021925824000176
  6. Dec 2023
  7. www.sciencedirect.com www.sciencedirect.com
    MORG1 limits mTORC1 signaling by inhibiting Rag GTPases
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    1. scibot 16 Dec 2023
      RRID:AB_10860252

      DOI: 10.1016/j.molcel.2023.11.023

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    sciencedirect.com/science/article/pii/S1097276523009681
  8. Jan 2023
  9. www.sciencedirect.com www.sciencedirect.com
    A central role for regulated protein stability in the control of TFE3 and MITF by nutrients
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    1. scibot 06 Jan 2023
      RRID:AB_10860252

      DOI: 10.1016/j.molcel.2022.12.013

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    sciencedirect.com/science/article/pii/S1097276522011704
  10. Dec 2022
  11. www.sciencedirect.com www.sciencedirect.com
    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
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    1. scibot 08 Dec 2022
      RRID:AB_10860252

      DOI: 10.1016/j.celrep.2022.111653

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    sciencedirect.com/science/article/pii/S2211124722015248
  12. Sep 2022
  13. www.cell.com www.cell.com
    Structure and mechanism of human cystine exporter cystinosin
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    1. scibot 17 Sep 2022
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      DOI: 10.1016/j.cell.2022.08.020

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    cell.com/cell/fulltext/S0092-8674(22)01114-X
  14. Feb 2022
  15. www.embopress.org www.embopress.org
    LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function
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    1. scibot 12 Feb 2022
      RRID:AB_10860252

      DOI: 10.15252/embj.2021108119

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    embopress.org/doi/abs/10.15252/embj.2021108119
  16. Aug 2021
  17. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 02 Aug 2021
      RRID:AB_10860252

      DOI: 10.1016/j.stem.2018.11.021

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    sciencedirect.com/science/article/pii/S1934590918305575
  18. Jul 2021
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 29 Jul 2021
      RRID:AB_10860252

      DOI: 10.1016/j.cmet.2018.08.013

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    ncbi.nlm.nih.gov/pmc/articles/PMC6331339/
  20. www.sciencedirect.com www.sciencedirect.com
    Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer
    1
    1. scibot 28 Jul 2021
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      DOI: 10.1016/j.ccell.2019.01.018

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    sciencedirect.com/science/article/pii/S1535610819300522
  21. May 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity
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    1. scibot 07 May 2021
      RRID:AB_10860252

      DOI: 10.1016/j.molcel.2020.10.004

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    sciencedirect.com/science/article/pii/S1097276520306870
  23. Feb 2021
  24. elifesciences.org elifesciences.org
    UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity
    1
    1. scibot 25 Feb 2021
      RRID:AB_10860252

      DOI: 10.7554/eLife.37993

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    elifesciences.org/articles/37993
  25. Nov 2018
  26. www.sciencedirect.com www.sciencedirect.com
    Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A
    1
    1. scibot 05 Nov 2018
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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S155041311830514X
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC6063731/
  28. www.sciencedirect.com www.sciencedirect.com
    Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1550413117306290