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20 Matching Annotations

Oct 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pathogenic mutations in ATAD3A cause dysregulation of RagC/D-TFEB axis and disrupt lysosomal homeostasis

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1. scibot 12 Oct 2026
  
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  RRID:AB_10860252
  
  DOI: 10.64898/2026.09.23.753918
  
  Resource: (Cell Signaling Technology Cat# 8975, RRID:AB_10860252)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13622220/
Jul 2025
www.science.org www.science.org

Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling

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1. scibot 25 Jul 2025
  
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  AB_10860252
  
  DOI: 10.1126/science.adm9805
  
  Resource: (Cell Signaling Technology Cat# 8975, RRID:AB_10860252)
  
  Curator: @sonofthor
  
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science.org/doi/10.1126/science.adm9805
Dec 2024
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 29 Dec 2024
  
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  RRID:AB_10860252
  
  DOI: 10.1172/jci183592
  
  Resource: (Cell Signaling Technology Cat# 8975, RRID:AB_10860252)
  
  Curator: @sjvitug
  
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52.53.155.43/6223e1a34d8b418f72131b1eba207b1427b70260/PDF-html.html
www.cell.com www.cell.com

TFEB triggers a matrix degradation and invasion program in triple-negative breast cancer cells upon mTORC1 repression

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1. scibot 29 Dec 2024
  
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  RRID:AB_10860252
  
  DOI: 10.1016/j.devcel.2024.12.005
  
  Resource: (Cell Signaling Technology Cat# 8975, RRID:AB_10860252)
  
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cell.com/developmental-cell/fulltext/S1534-5807(24)00727-5
www.nature.com www.nature.com

Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing

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1. scibot 21 Dec 2024
  
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  RRID:AB_10860252
  
  DOI: 10.1038/s41586-024-08348-2
  
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nature.com/articles/s41586-024-08348-2
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The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation

1
1. scibot 21 Dec 2024
  
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  RRID:AB_10860252
  
  DOI: 10.1016/j.celrep.2024.115101
  
  Resource: (Cell Signaling Technology Cat# 8975, RRID:AB_10860252)
  
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sciencedirect.com/science/article/pii/S2211124724014529
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease

1
1. scibot 11 Jan 2024
  
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  RRID:AB_10860252
  
  DOI: 10.1016/j.jbc.2024.105641
  
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sciencedirect.com/science/article/pii/S0021925824000176
Dec 2023
www.sciencedirect.com www.sciencedirect.com

MORG1 limits mTORC1 signaling by inhibiting Rag GTPases

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1. scibot 16 Dec 2023
  
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  RRID:AB_10860252
  
  DOI: 10.1016/j.molcel.2023.11.023
  
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sciencedirect.com/science/article/pii/S1097276523009681
Jan 2023
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A central role for regulated protein stability in the control of TFE3 and MITF by nutrients

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1. scibot 06 Jan 2023
  
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  RRID:AB_10860252
  
  DOI: 10.1016/j.molcel.2022.12.013
  
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sciencedirect.com/science/article/pii/S1097276522011704
Dec 2022
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USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction

1
1. scibot 08 Dec 2022
  
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  RRID:AB_10860252
  
  DOI: 10.1016/j.celrep.2022.111653
  
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sciencedirect.com/science/article/pii/S2211124722015248
Sep 2022
www.cell.com www.cell.com

Structure and mechanism of human cystine exporter cystinosin

1
1. scibot 17 Sep 2022
  
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  RRID:AB_10860252
  
  DOI: 10.1016/j.cell.2022.08.020
  
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cell.com/cell/fulltext/S0092-8674(22)01114-X
Feb 2022
www.embopress.org www.embopress.org

LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function

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1. scibot 12 Feb 2022
  
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  RRID:AB_10860252
  
  DOI: 10.15252/embj.2021108119
  
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embopress.org/doi/abs/10.15252/embj.2021108119
Aug 2021
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Untitled document

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1. scibot 02 Aug 2021
  
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  RRID:AB_10860252
  
  DOI: 10.1016/j.stem.2018.11.021
  
  Resource: (Cell Signaling Technology Cat# 8975, RRID:AB_10860252)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1934590918305575
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 29 Jul 2021
  
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  RRID:AB_10860252
  
  DOI: 10.1016/j.cmet.2018.08.013
  
  Resource: (Cell Signaling Technology Cat# 8975, RRID:AB_10860252)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6331339/
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Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer

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1. scibot 28 Jul 2021
  
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  RRID:AB_10860252
  
  DOI: 10.1016/j.ccell.2019.01.018
  
  Resource: (Cell Signaling Technology Cat# 8975, RRID:AB_10860252)
  
  Curator: @bandrow
  
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sciencedirect.com/science/article/pii/S1535610819300522
May 2021
www.sciencedirect.com www.sciencedirect.com

Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity

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1. scibot 07 May 2021
  
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  RRID:AB_10860252
  
  DOI: 10.1016/j.molcel.2020.10.004
  
  Resource: (Cell Signaling Technology Cat# 8975, RRID:AB_10860252)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1097276520306870
Feb 2021
elifesciences.org elifesciences.org

UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity

1
1. scibot 25 Feb 2021
  
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  RRID:AB_10860252
  
  DOI: 10.7554/eLife.37993
  
  Resource: (Cell Signaling Technology Cat# 8975, RRID:AB_10860252)
  
  Curator: @scibot
  
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elifesciences.org/articles/37993
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A

1
1. scibot 05 Nov 2018
  
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  RRID:AB_10860252
  
  Curator: @evieth
  
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  (Cell Signaling Technology Cat# 8975S, RRID:AB_10860252)
  
  SciCrunch record: RRID:AB_10860252
  
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  RRID:AB_10860252 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S155041311830514X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 05 Nov 2018
  
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  RRID:AB_10860252
  
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  (Cell Signaling Technology Cat# 8975S, RRID:AB_10860252)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6063731/
www.sciencedirect.com www.sciencedirect.com

Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations

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1. scibot 05 Nov 2018
  
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  RRID:AB_10860252
  
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  (Cell Signaling Technology Cat# 8975S, RRID:AB_10860252)
  
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sciencedirect.com/science/article/pii/S1550413117306290