90 Matching Annotations
  1. Last 7 days
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    The Drosophila Hippo pathway transcription factor Scalloped and its co-factors alter each other’s chromatin binding dynamics and transcription in vivo
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    1. scibot 26 Apr 2024
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      DOI: 10.1016/j.devcel.2024.04.006

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    sciencedirect.com/science/article/pii/S1534580724002314
  3. Apr 2024
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    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
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    1. scibot 18 Apr 2024
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    2. scibot 18 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114094

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    sciencedirect.com/science/article/pii/S2211124724004224
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    SP6 controls human cytotrophoblast fate decisions and trophoblast stem cell establishment by targeting MSX2 regulatory elements
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    1. scibot 09 Apr 2024
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      DOI: 10.1016/j.devcel.2024.03.025

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    sciencedirect.com/science/article/pii/S153458072400193X
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114065

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    sciencedirect.com/science/article/pii/S2211124724003930
  7. Mar 2024
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    1. scibot 29 Mar 2024
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    sciencedirect.com/science/article/pii/S1097276524001758
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    Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
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    sciencedirect.com/science/article/pii/S2211124724002031
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    Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability
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    1. scibot 06 Mar 2024
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    2. scibot 06 Mar 2024
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    sciencedirect.com/science/article/pii/S1550413124000500
  11. Feb 2024
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    Canonical Wnt signaling directs the generation of functional human PSC-derived atrioventricular canal cardiomyocytes in bioprinted cardiac tissues
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    1. scibot 24 Feb 2024
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      DOI: 10.1016/j.stem.2024.01.008

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    sciencedirect.com/science/article/pii/S1934590924000389
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    Selection of epigenetically privileged HIV-1 proviruses during treatment with panobinostat and interferon-α2a
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    1. scibot 21 Feb 2024
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      DOI: 10.1016/j.cell.2024.01.037

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    2. scibot 21 Feb 2024
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    sciencedirect.com/science/article/pii/S0092867424001053
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    Lactic acid induces transcriptional repression of macrophage inflammatory response via histone acetylation
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    1. scibot 09 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724000743
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    H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells
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    1. scibot 02 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724000354
  16. Jan 2024
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    Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity
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    1. scibot 19 Jan 2024
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    sciencedirect.com/science/article/pii/S1550413123004679
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    IL-15-dependent immune crosstalk between natural killer cells and dendritic cells in HIV-1 elite controllers
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    1. scibot 12 Jan 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10765318/
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    Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression
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    1. scibot 11 Jan 2024
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    sciencedirect.com/science/article/pii/S2211124723015875
  20. Dec 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions
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    1. scibot 02 Dec 2023
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      DOI: 10.1016/j.isci.2023.108446

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    ncbi.nlm.nih.gov/pmc/articles/PMC10687339/
  22. www.science.org www.science.org
    KDM6B drives epigenetic reprogramming associated with lymphoid stromal cell early commitment and immune properties
    2
    1. scibot 02 Dec 2023
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      DOI: 10.1126/sciadv.adh2708

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    2. scibot 01 Dec 2023
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      DOI: 10.1126/sciadv.adh2708

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    science.org/doi/10.1126/sciadv.adh2708
  23. Oct 2023
  24. 52.53.155.43 52.53.155.43
    PIIS0092867423009650-html.html
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    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.cell.2023.08.032

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    52.53.155.43/10a4fc8c2567a3934d6a2c0730d82b14865b6e30/PIIS0092867423009650-html.html
  25. Sep 2023
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    Discordant interactions between YAP1 and polycomb group protein SCML2 determine cell fate
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    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.isci.2023.107964

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    sciencedirect.com/science/article/pii/S2589004223020412
  27. Aug 2023
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    The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function
    1
    1. scibot 25 Aug 2023
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      DOI: 10.1016/j.celrep.2023.113013

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    sciencedirect.com/science/article/pii/S2211124723010240
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    NFYC-37 promotes tumor growth by activating the mevalonate pathway in bladder cancer
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    1. scibot 17 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112963

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    52.53.155.43/eb7aace05cf7a189f4453bfbeb3bcf344412f769/mmc4-html.html
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    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
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      DOI: 10.1016/j.ccell.2023.07.005

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    sciencedirect.com/science/article/pii/S1535610823002453
  31. Jul 2023
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    Ketolysis drives CD8+ T cell effector function through effects on histone acetylation
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    1. scibot 29 Jul 2023
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      DOI: 10.1016/j.immuni.2023.07.002

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    sciencedirect.com/science/article/pii/S107476132300314X
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    A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression
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    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112833

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    sciencedirect.com/science/article/pii/S2211124723008446
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    Single-cell dissection of Merkel cell carcinoma heterogeneity unveils transcriptomic plasticity and therapeutic vulnerabilities
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    1. scibot 08 Jul 2023
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      DOI: 10.1016/j.xcrm.2023.101101

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    sciencedirect.com/science/article/pii/S2666379123002203
  35. Jun 2023
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    Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation
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    1. scibot 07 Jun 2023
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      DOI: 10.1016/j.immuni.2023.05.010

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    sciencedirect.com/science/article/pii/S1074761323002273
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    Complex regulation of Eomes levels mediated through distinct functional features of the Meteor long non-coding RNA locus
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      DOI: 10.1016/j.celrep.2023.112569

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    sciencedirect.com/science/article/pii/S2211124723005806
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    (A) Elevated expression of histone deacetylase HDAC8 suppresses arginine-proline metabolism in necrotizing enterocolitis
    1
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      DOI: 10.1016/j.isci.2023.106882

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    ncbi.nlm.nih.gov/pmc/articles/PMC10227426/
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    Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation
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    sciencedirect.com/science/article/pii/S1074761323002212
  40. May 2023
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    Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis
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      DOI: 10.1016/j.celrep.2023.112550

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    sciencedirect.com/science/article/pii/S2211124723005612
  42. Apr 2023
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    DNA-initiated epigenetic cascades driven by C9orf72 hexanucleotide repeat
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      DOI: 10.1016/j.neuron.2023.01.022

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    sciencedirect.com/science/article/pii/S0896627323000727
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    Novel enhancers conferring compensatory transcriptional regulation of Nkx2-5 in heart development
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      DOI: 10.1016/j.isci.2023.106509

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    sciencedirect.com/science/article/pii/S2589004223005862
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    MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer
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      DOI: 10.1016/j.xcrm.2023.101006

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    sciencedirect.com/science/article/pii/S2666379123001167
  46. Feb 2023
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    Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation
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      DOI: 10.1016/j.celrep.2023.112033

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    sciencedirect.com/science/article/pii/S221112472300044X
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    D-2-hydroxyglutarate dehydrogenase governs adult neural stem cell activation and promotes histone acetylation via ATP-citrate lyase
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      DOI: 10.1016/j.celrep.2023.112067

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    sciencedirect.com/science/article/pii/S2211124723000785
  49. Jan 2023
  50. www.sciencedirect.com www.sciencedirect.com
    Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1
    1
    1. scibot 28 Jan 2023
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      DOI: 10.1016/j.neuron.2022.11.016

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    sciencedirect.com/science/article/pii/S0896627322010704
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors
    1
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  54. Dec 2022
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  59. Nov 2022
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    Pharmacological preconditioning by TERT inhibitor BIBR1532 confers neuronal ischemic tolerance through TERT-mediated transcriptional reprogramming
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  83. Aug 2021
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    Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements
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  85. Jul 2021
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    Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements
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      RRID:AB_10949503 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867419309018
  111. www.sciencedirect.com www.sciencedirect.com
    Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949503

      DOI: 10.1016/j.cell.2019.07.048

      Resource: (Cell Signaling Technology Cat# 8173, RRID:AB_10949503)

      Curator: @ethanbadger

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      RRID:AB_10949503 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867419308487
  112. www.sciencedirect.com www.sciencedirect.com
    A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949503

      DOI: 10.1016/j.celrep.2019.10.011

      Resource: (Cell Signaling Technology Cat# 8173, RRID:AB_10949503)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124719313117
  113. www.sciencedirect.com www.sciencedirect.com
    p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949503

      DOI: 10.1016/j.celrep.2019.07.027

      Resource: (Cell Signaling Technology Cat# 8173, RRID:AB_10949503)

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      RRID:AB_10949503 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719309246
  114. www.sciencedirect.com www.sciencedirect.com
    The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949503

      DOI: 10.1016/j.immuni.2018.12.018

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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S1074761318305661
  115. www.sciencedirect.com www.sciencedirect.com
    LRH1-driven transcription factor circuitry for hepatocyte identity: Super-enhancer cistromic analysis
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949503

      DOI: 10.1016/j.ebiom.2018.12.056

      Resource: (Cell Signaling Technology Cat# 8173, RRID:AB_10949503)

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S2352396418306339
  116. Nov 2018
  117. www.sciencedirect.com www.sciencedirect.com
    Mutant NPM1 Maintains the Leukemic State through HOX Expression
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    1. scibot 05 Nov 2018
      RRID:AB_10949503

      Curator: @Jmenke

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      RRID:AB_10949503 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610818303593
  118. www.sciencedirect.com www.sciencedirect.com
    SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
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    1. scibot 05 Nov 2018
      RRID:AB_10949503

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    sciencedirect.com/science/article/pii/S1934590918303850
  119. www.sciencedirect.com www.sciencedirect.com
    A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer
    1
    1. scibot 05 Nov 2018
      RRID:AB_10949503

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      (Cell Signaling Technology Cat# 8173S, RRID:AB_10949503)

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      RRID:AB_10949503
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    sciencedirect.com/science/article/pii/S0092867418306494