62 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Stochastic modeling of single-cell gene expression adaptation reveals non-genomic contribution to evolution of tumor subclones
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    1. scibot 19 Dec 2024
      RRID:AB_10949609

      DOI: 10.1016/j.cels.2024.11.013

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    sciencedirect.com/science/article/pii/S2405471224003491
  3. Dec 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Botensilimab, an Fc-Enhanced Anti–CTLA-4 Antibody, Is Effective against Tumors Poorly Responsive to Conventional Immunotherapy
    1
    1. scibot 11 Dec 2024
      RRID:AB_10949609

      DOI: 10.1158/2159-8290.CD-24-0190

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    pmc.ncbi.nlm.nih.gov/articles/PMC11609826/
  5. Aug 2024
  6. 52.53.155.43 52.53.155.43
    Fc-enhanced anti-CTLA-4, anti-PD-1, doxorubicin, and ultrasound-mediated BBB opening: A novel combinatorial immunotherapy regimen for gliomas
    1
    1. scibot 22 Aug 2024
      AB_10949609

      DOI: 10.1093/neuonc/noae135

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    52.53.155.43/b26c2f5d2e25d24d055f7a85c9e119457013d301/noae135-html.html
  7. Jun 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule
    1
    1. scibot 05 Jun 2024
      RRID:AB_10949609

      DOI: 10.1016/j.cmet.2024.05.001

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    sciencedirect.com/science/article/pii/S1550413124001773
  9. May 2024
  10. www.sciencedirect.com www.sciencedirect.com
    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
    1
    1. scibot 24 May 2024
      RRID:AB_10949609

      DOI: 10.1016/j.immuni.2024.04.025

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    sciencedirect.com/science/article/pii/S1074761324002309
  11. Mar 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers
    1
    1. scibot 15 Mar 2024
      RRID:AB_10949609

      DOI: 10.1016/j.ccell.2024.02.013

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    sciencedirect.com/science/article/pii/S1535610824000576
  13. Feb 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Lactate modulates RNA splicing to promote CTLA-4 expression in tumor-infiltrating regulatory T cells
    2
    1. scibot 29 Feb 2024
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      DOI: 10.1016/j.immuni.2024.01.019

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    2. scibot 29 Feb 2024
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      DOI: 10.1016/j.immuni.2024.01.019

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    sciencedirect.com/science/article/pii/S1074761324000451
  15. Dec 2023
  16. www.sciencedirect.com www.sciencedirect.com
    NK cells propagate T cell immunity following in situ tumor vaccination
    1
    1. scibot 17 Dec 2023
      RRID:AB_10949609

      DOI: 10.1016/j.celrep.2023.113556

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    sciencedirect.com/science/article/pii/S2211124723015681
  17. Oct 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer
    1
    1. scibot 01 Oct 2023
      RRID:AB_10949609

      DOI: 10.1016/j.isci.2023.107937

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    sciencedirect.com/science/article/pii/S258900422302014X
  19. Jul 2023
  20. www.sciencedirect.com www.sciencedirect.com
    A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.xcrm.2023.101113

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    sciencedirect.com/science/article/pii/S2666379123002410
  21. May 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal
    1
    1. scibot 05 May 2023
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      DOI: 10.1016/j.stem.2023.04.005

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    sciencedirect.com/science/article/pii/S1934590923001236
  23. Apr 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma
    1
    1. scibot 12 Apr 2023
      RRID:AB_10949609

      DOI: 10.1016/j.xcrm.2023.101009

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    sciencedirect.com/science/article/pii/S2666379123001192
  25. www.cell.com www.cell.com
    Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment
    1
    1. scibot 07 Apr 2023
      RRID:AB_10949609

      DOI: 10.1016/j.cell.2023.03.011

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    cell.com/cell/fulltext/S0092-8674(23)00271-4
  26. www.sciencedirect.com www.sciencedirect.com
    T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants
    1
    1. scibot 04 Apr 2023
      RRID:AB_10949609

      DOI: 10.1016/j.cell.2023.03.007

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    sciencedirect.com/science/article/pii/S0092867423002258
  27. www.sciencedirect.com www.sciencedirect.com
    A neutrophil response linked to tumor control in immunotherapy
    1
    1. scibot 04 Apr 2023
      RRID:AB_10949609

      DOI: 10.1016/j.cell.2023.02.032

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    sciencedirect.com/science/article/pii/S0092867423002106
  28. Mar 2023
  29. www.sciencedirect.com www.sciencedirect.com
    IFNγ is a central node of cancer immune equilibrium
    1
    1. scibot 09 Mar 2023
      RRID:AB_10949609

      DOI: 10.1016/j.celrep.2023.112219

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    sciencedirect.com/science/article/pii/S2211124723002309
  30. Jan 2023
  31. www.sciencedirect.com www.sciencedirect.com
    The loss of epithelial Smad4 drives immune evasion via CXCL1 while displaying vulnerability to combinatorial immunotherapy in gastric cancer
    1
    1. scibot 28 Jan 2023
      RRID:AB_10949609

      DOI: 10.1016/j.celrep.2022.111878

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    sciencedirect.com/science/article/pii/S2211124722017740
  32. www.sciencedirect.com www.sciencedirect.com
    MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors
    1
    1. scibot 19 Jan 2023
      RRID:AB_10949609

      DOI: 10.1016/j.ccell.2022.12.007

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    sciencedirect.com/science/article/pii/S1535610822005931
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy
    1
    1. scibot 07 Jan 2023
      RRID:AB_10949609

      DOI: 10.1158/2159-8290.CD-21-0003

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    ncbi.nlm.nih.gov/pmc/articles/PMC9401506/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1
    1
    1. scibot 07 Jan 2023
      RRID:AB_10949609

      DOI: 10.1158/2159-8290.CD-21-0900

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    ncbi.nlm.nih.gov/pmc/articles/PMC9262841/
  35. Dec 2022
  36. www.sciencedirect.com www.sciencedirect.com
    Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer
    1
    1. scibot 17 Dec 2022
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      DOI: 10.1016/j.ccell.2022.11.016

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    sciencedirect.com/science/article/pii/S1535610822005633
  37. www.sciencedirect.com www.sciencedirect.com
    IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer
    1
    1. scibot 17 Dec 2022
      RRID:AB_10949609

      DOI: 10.1016/j.ccell.2022.11.014

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    sciencedirect.com/science/article/pii/S153561082200561X
  38. aacrjournals.org aacrjournals.org
    Depletion of conventional type-1 dendritic cells in established tumors suppresses immunotherapy efficacy
    1
    1. scibot 03 Dec 2022
      RRID:AB_10949609

      DOI: 10.1158/0008-5472.CAN-22-1046

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    aacrjournals.org/cancerres/article/82/23/4373/710691/Depletion-of-Conventional-Type-1-Dendritic-Cells
  39. 52.53.155.43 52.53.155.43
    can-22-1046-html.html
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      DOI: 10.1158/0008-5472.can-22-1046

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    52.53.155.43/31121aea6deac1c0e5bfa6acfce4eeee5d0658c1/can-22-1046-html.html
  40. Nov 2022
  41. www.cell.com www.cell.com
    Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop
    1
    1. scibot 24 Nov 2022
      RRID:AB_10949609

      DOI: 10.1016/j.ccell.2022.11.002

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    cell.com/cancer-cell/fulltext/S1535-6108(22)00549-9
  42. aacrjournals.org aacrjournals.org
    A novel selective inhibitor JBI-589 targets PAD4-mediated neutrophil migration to suppress tumor progression
    1
    1. scibot 22 Nov 2022
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      DOI: 10.1158/0008-5472.CAN-21-4045

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    aacrjournals.org/cancerres/article/82/19/3561/709408/A-Novel-Selective-Inhibitor-JBI-589-Targets-PAD4
  43. Sep 2022
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
    1
    1. scibot 02 Sep 2022
      RRID:AB_10949609

      DOI: 10.1158/2159-8290.CD-21-1077

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    ncbi.nlm.nih.gov/pmc/articles/PMC8904298/
  45. Jun 2022
  46. 52.53.155.43 52.53.155.43
    cd-21-0900-html.html
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    1. scibot 30 Jun 2022
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      DOI: 10.1158/2159-8290.cd-21-0900

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    2. scibot 25 Jun 2022
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      DOI: 10.1158/2159-8290.cd-21-0900

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    3. scibot 22 Jun 2022
      RRID:AB_10949609

      DOI: 10.1158/2159-8290.cd-21-0900

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    52.53.155.43/d5bf83c5c1736aa8a79b5cf8b82689398b415edf/cd-21-0900 (2)-html.html
  47. www.sciencedirect.com www.sciencedirect.com
    Flow cytometry analysis of endothelial cells and subsets of exhausted CD8+ T cells in murine tumor models
    1
    1. scibot 09 Jun 2022
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      DOI: 10.1016/j.xpro.2022.101444

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    sciencedirect.com/science/article/pii/S2666166722003240
  48. Feb 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy
    1
    1. scibot 04 Feb 2022
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      DOI: 10.1016/j.ccell.2022.01.002

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    sciencedirect.com/science/article/pii/S1535610822000046
  50. Nov 2021
  51. www.sciencedirect.com www.sciencedirect.com
    The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1
    1
    1. scibot 25 Nov 2021
      RRID:AB_10949609

      DOI: 10.1016/j.ccell.2021.11.002

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    sciencedirect.com/science/article/pii/S1535610821006024
  52. mct.aacrjournals.org mct.aacrjournals.org
    Simultaneously Combined Cancer Cell- and CTLA4-Targeted NIR-PIT Causes a Synergistic Treatment Effect in Syngeneic Mouse Models
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    1. scibot 24 Nov 2021
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      DOI: 10.1158/1535-7163.MCT-21-0470

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    mct.aacrjournals.org/content/20/11/2262
  53. www.sciencedirect.com www.sciencedirect.com
    Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation
    1
    1. scibot 05 Nov 2021
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      DOI: 10.1016/j.ccell.2021.10.008

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    sciencedirect.com/science/article/pii/S1535610821005596
  54. Oct 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Inhibition of the BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage dendritic cells and enhances anti-tumor T cell immunity
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    1. scibot 06 Oct 2021
      RRID:AB_10949609

      DOI: 10.1016/j.immuni.2021.09.005

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    sciencedirect.com/science/article/pii/S1074761321003903
  56. Sep 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma
    1
    1. scibot 15 Sep 2021
      RRID:AB_10949609

      DOI: 10.1016/j.xcrm.2021.100399

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    sciencedirect.com/science/article/pii/S2666379121002573
  58. Aug 2021
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 11 Aug 2021
      RRID:AB_10949609

      DOI: 10.1016/j.immuni.2017.11.003

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    ncbi.nlm.nih.gov/pmc/articles/PMC5759774/
  60. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 09 Aug 2021
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      DOI: 10.1016/j.celrep.2018.11.047

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    sciencedirect.com/science/article/pii/S2211124718318102
  61. www.sciencedirect.com www.sciencedirect.com
    Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function
    1
    1. scibot 05 Aug 2021
      RRID:AB_10949609

      DOI: 10.1016/j.immuni.2018.09.014

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    sciencedirect.com/science/article/pii/S1074761318304291
  62. Jul 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
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    1. scibot 30 Jul 2021
      RRID:AB_10949609

      DOI: 10.1016/j.cell.2018.10.038

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    sciencedirect.com/science/article/pii/S0092867418313941
  64. www.sciencedirect.com www.sciencedirect.com
    Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING
    1
    1. scibot 23 Jul 2021
      RRID:AB_10949609

      DOI: 10.1016/j.celrep.2021.109412

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    sciencedirect.com/science/article/pii/S2211124721008251
  65. Jun 2021
  66. www.sciencedirect.com www.sciencedirect.com
    Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity
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    1. scibot 03 Jun 2021
      RRID:AB_10949609

      DOI: 10.1016/j.cell.2021.05.021

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    sciencedirect.com/science/article/pii/S0092867421006516
  67. Apr 2021
  68. www.sciencedirect.com www.sciencedirect.com
    Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade
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    1. scibot 28 Apr 2021
      RRID:AB_10949609

      DOI: 10.1016/j.molcel.2021.03.037

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  69. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
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    1. scibot 06 Apr 2021
      InVivoPlus anti-mouse CTLA-4 (CD152) Anti-CTLA-4 Mouse Monoclonal Antibody

      DOI: 10.1016/j.immuni.2021.02.020

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    sciencedirect.com/science/article/pii/S1074761321000868
  70. Feb 2021
  71. www.sciencedirect.com www.sciencedirect.com
    DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity
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    1. scibot 28 Feb 2021
      RRID:AB_10949609

      DOI: 10.1016/j.ccell.2020.11.006

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    sciencedirect.com/science/article/pii/S1535610820305985
  72. Sep 2020
  73. www.cell.com www.cell.com
    Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction
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    1. scibot 15 Sep 2020
      RRID:AB_10949609

      DOI: 10.1016/j.immuni.2017.11.003

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    cell.com/immunity/abstract/S1074-7613(17)30480-6
  74. www.sciencedirect.com www.sciencedirect.com
    An Agonistic Anti-CD137 Antibody Disrupts Lymphoid Follicle Structure and T-Cell-Dependent Antibody Responses
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    1. scibot 06 Sep 2020
      RRID:AB_10949609

      DOI: 10.1016/j.xcrm.2020.100035

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    sciencedirect.com/science/article/pii/S2666379120300471
  75. Jan 2020
  76. www.sciencedirect.com www.sciencedirect.com
    Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
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    1. scibot 13 Jan 2020
      RRID:AB_10949609

      DOI: 10.1016/j.celrep.2019.08.068

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    sciencedirect.com/science/article/pii/S2211124719311234
  77. www.sciencedirect.com www.sciencedirect.com
    B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer
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    1. scibot 13 Jan 2020
      RRID:AB_10949609

      DOI: 10.1016/j.cell.2019.10.028

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    sciencedirect.com/science/article/pii/S009286741931178X
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer
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    1. scibot 13 Jan 2020
      RRID:AB_10949609

      DOI: 10.1016/j.celrep.2019.03.066

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    ncbi.nlm.nih.gov/pmc/articles/PMC6719696/
  79. www.sciencedirect.com www.sciencedirect.com
    PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949609

      DOI: 10.1016/j.immuni.2019.11.003

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    sciencedirect.com/science/article/pii/S1074761319304613
  80. www.sciencedirect.com www.sciencedirect.com
    Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949609

      DOI: 10.1016/j.cell.2019.07.019

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    sciencedirect.com/science/article/pii/S0092867419307846
  81. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_10949609

      DOI: 10.1016/j.immuni.2018.12.021

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    sciencedirect.com/science/article/pii/S1074761318305697
  82. www.sciencedirect.com www.sciencedirect.com
    Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation
    1
    1. scibot 12 Jan 2020
      RRID:AB_10949609

      DOI: 10.1016/j.ccell.2019.04.003

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    sciencedirect.com/science/article/pii/S1535610819301989
  83. Nov 2018
  84. www.sciencedirect.com www.sciencedirect.com
    High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy
    1
    1. scibot 05 Nov 2018
      RRID:AB_10949609

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    sciencedirect.com/science/article/pii/S009286741831242X
  85. www.sciencedirect.com www.sciencedirect.com
    IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy
    1
    1. scibot 05 Nov 2018
      RRID:AB_10949609

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    sciencedirect.com/science/article/pii/S2405471218302382
  86. www.sciencedirect.com www.sciencedirect.com
    Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T Cell Antigens
    1
    1. scibot 05 Nov 2018
      RRID:AB_10949609

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    sciencedirect.com/science/article/pii/S1535610818302198
  87. www.sciencedirect.com www.sciencedirect.com
    Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity
    1
    1. scibot 05 Nov 2018
      RRID:AB_10949609

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    sciencedirect.com/science/article/pii/S153561081830223X
  88. www.sciencedirect.com www.sciencedirect.com
    Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment
    1
    1. scibot 05 Nov 2018
      RRID:AB_10949609

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    sciencedirect.com/science/article/pii/S1535610817304713
  89. www.sciencedirect.com www.sciencedirect.com
    Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction
    1
    1. scibot 05 Nov 2018
      RRID:AB_10949609

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    sciencedirect.com/science/article/pii/S1074761317304806