53 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance
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    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.cell.2024.06.012

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  3. Jun 2024
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    Glycoengineering-based anti-PD-1-iRGD peptide conjugate boosts antitumor efficacy through T cell engagement
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    1. scibot 06 Jun 2024
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      DOI: 10.1016/j.xcrm.2024.101590

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    Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity
    1
    1. scibot 04 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114300

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    sciencedirect.com/science/article/pii/S2211124724006284
  6. May 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect
    1
    1. scibot 15 May 2024
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      DOI: 10.1084/jem.20221122

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    ncbi.nlm.nih.gov/pmc/articles/PMC11082451/
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    Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy
    1
    1. scibot 09 May 2024
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    sciencedirect.com/science/article/pii/S0092867424004100
  9. Apr 2024
  10. www.nature.com www.nature.com
    Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade
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    1. scibot 03 Apr 2024
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      DOI: 10.1038/s41467-024-47069-y

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    nature.com/articles/s41467-024-47069-y
  11. Mar 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers
    1
    1. scibot 15 Mar 2024
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      DOI: 10.1016/j.ccell.2024.02.013

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    sciencedirect.com/science/article/pii/S1535610824000576
  13. Feb 2024
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    UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity
    1
    1. scibot 28 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.024

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    sciencedirect.com/science/article/pii/S1097276524000911
  15. Jan 2024
  16. 52.53.155.43 52.53.155.43
    Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors
    1
    1. scibot 10 Jan 2024
      RRID:AB_10950145

      DOI: 10.1126/sciimmunol.abq2424

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  17. Nov 2023
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    PD-L1-mediated immune evasion in triple-negative breast cancer is linked to the loss of ZNF652
    1
    1. scibot 02 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113343

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    sciencedirect.com/science/article/pii/S2211124723013554
  19. Oct 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Dietary fructose-mediated adipocyte metabolism drives antitumor CD8+ T cell responses
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.cmet.2023.09.011

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    sciencedirect.com/science/article/pii/S1550413123003674
  21. Sep 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity
    1
    1. scibot 30 Sep 2023
      RRID:AB_10950145

      DOI: 10.1016/j.xcrm.2023.101206

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    sciencedirect.com/science/article/pii/S2666379123003737
  23. Aug 2023
  24. 52.53.155.43 52.53.155.43
    CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells
    2
    1. scibot 17 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101151

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    2. scibot 11 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101151

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  25. Jun 2023
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    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
    1
    1. scibot 28 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112693

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    sciencedirect.com/science/article/pii/S2211124723007040
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    ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112654

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    sciencedirect.com/science/article/pii/S2211124723006654
  28. May 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment
    1
    1. scibot 13 May 2023
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      DOI: 10.1016/j.cmet.2023.04.017

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    sciencedirect.com/science/article/pii/S1550413123001717
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    Fusobacterium nucleatum-derived succinic acid induces tumor resistance to immunotherapy in colorectal cancer
    1
    1. scibot 03 May 2023
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      DOI: 10.1016/j.chom.2023.04.010

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    sciencedirect.com/science/article/abs/pii/S1931312823001610
  31. Apr 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response
    1
    1. scibot 20 Apr 2023
      RRID:AB_10950145

      DOI: 10.1016/j.celrep.2023.112186

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    sciencedirect.com/science/article/pii/S2211124723001973
  33. Feb 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer
    1
    1. scibot 04 Feb 2023
      RRID:AB_10950145

      DOI: 10.1158/2326-6066.CIR-22-0088

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    ncbi.nlm.nih.gov/pmc/articles/PMC9357105/
  35. Jan 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy
    1
    1. scibot 19 Jan 2023
      RRID:AB_10950145

      DOI: 10.1016/j.ccell.2022.12.008

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    sciencedirect.com/science/article/pii/S1535610822005943
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance
    1
    1. scibot 11 Jan 2023
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      DOI: 10.1158/2159-8290.CD-21-1463

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    ncbi.nlm.nih.gov/pmc/articles/PMC9357203/
  38. Oct 2022
  39. www.science.org www.science.org
    PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
    1
    1. scibot 25 Oct 2022
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      DOI: 10.1126/sciadv.abn6545

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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
    1
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      DOI: 10.1126/sciadv.abn6545

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    ncbi.nlm.nih.gov/pmc/articles/PMC9491709/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NOTCH induced MDSC recruitment after oHSV virotherapy in CNS cancer models modulates anti-tumor immunotherapy
    1
    1. scibot 04 Oct 2022
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      DOI: 10.1158/1078-0432.CCR-21-2347

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    ncbi.nlm.nih.gov/pmc/articles/PMC8976724/
  42. Jul 2022
  43. 52.53.155.43 52.53.155.43
    cir-22-0088-html.html
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    1. scibot 29 Jul 2022
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      DOI: 10.1158/2326-6066.cir-22-0088

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    52.53.155.43/a65b09b78e7767f723c9ad153c89aec9ed13d4e6/cir-22-0088-html.html
  44. Jun 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling
    1
    1. scibot 22 Jun 2022
      RRID:AB_10950145

      DOI: 10.1016/j.chembiol.2022.05.012

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    sciencedirect.com/science/article/pii/S2451945622002045
  46. May 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
    1
    1. scibot 12 May 2022
      RRID:AB_10950145

      DOI: 10.1016/j.cell.2022.04.019

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    sciencedirect.com/science/article/pii/S0092867422004664
  48. Feb 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity
    2
    1. scibot 11 Feb 2022
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      DOI: 10.1016/j.immuni.2022.01.006

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    2. scibot 09 Feb 2022
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      DOI: 10.1016/j.immuni.2022.01.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC8888129/
  50. Jan 2022
  51. www.sciencedirect.com www.sciencedirect.com
    TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures
    1
    1. scibot 12 Jan 2022
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      DOI: 10.1016/j.immuni.2021.12.007

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    sciencedirect.com/science/article/pii/S1074761321005434
  52. Dec 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Microbiota-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer
    1
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      DOI: 10.1016/j.immuni.2021.11.003

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    sciencedirect.com/science/article/pii/S1074761321004945
  54. Nov 2021
  55. www.sciencedirect.com www.sciencedirect.com
    The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1
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      DOI: 10.1016/j.ccell.2021.11.002

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    sciencedirect.com/science/article/pii/S1535610821006024
  56. Aug 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy
    1
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      DOI: 10.1016/j.ccell.2021.07.023

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    sciencedirect.com/science/article/pii/S1535610821004025
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 10 Aug 2021
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      DOI: 10.1016/j.chom.2018.11.011

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    ncbi.nlm.nih.gov/pmc/articles/PMC6331384/
  59. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 09 Aug 2021
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      DOI: 10.1016/j.cell.2018.10.014

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    sciencedirect.com/science/article/pii/S0092867418313229
  60. www.sciencedirect.com www.sciencedirect.com
    CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment
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    1. scibot 05 Aug 2021
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      DOI: 10.1016/j.cell.2021.07.015

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    sciencedirect.com/science/article/pii/S0092867421008564
  61. Jul 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endogenous Retrovirus Envelope as a Tumor-Associated Immunotherapeutic Target in Murine Osteosarcoma
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      RRID:AB_10950145

      DOI: 10.1016/j.isci.2021.102759

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    ncbi.nlm.nih.gov/pmc/articles/PMC8267546/
  63. Apr 2021
  64. www.sciencedirect.com www.sciencedirect.com
    Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors
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      DOI: 10.1016/j.celrep.2021.108944

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  65. Feb 2021
  66. elifesciences.org elifesciences.org
    Cytomegalovirus restricts ICOSL expression on antigen-presenting cells disabling T cell co-stimulation and contributing to immune evasion
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    1. scibot 04 Feb 2021
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      DOI: 10.7554/eLife.59350

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  67. Jan 2021
  68. www.sciencedirect.com www.sciencedirect.com
    Systemic Inflammation Suppresses Lymphoid Tissue Remodeling and B Cell Immunity during Concomitant Local Infection
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      RRID:AB_10950145

      DOI: 10.1016/j.celrep.2020.108567

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    sciencedirect.com/science/article/pii/S2211124720315564
  69. Nov 2020
  70. www.sciencedirect.com www.sciencedirect.com
    Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade
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      DOI: 10.1016/j.immuni.2020.10.020

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  71. Sep 2020
  72. www.sciencedirect.com www.sciencedirect.com
    Control of Viral Infection by Natural Killer Cell Inhibitory Receptors
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      DOI: 10.1016/j.celrep.2020.107969

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  73. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence and Response
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    1. scibot 15 Sep 2020
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      DOI: 10.1016/j.celrep.2020.108085

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  74. www.sciencedirect.com www.sciencedirect.com
    ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis
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      DOI: 10.1016/j.ccell.2020.02.006

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  75. Jan 2020
  76. www.sciencedirect.com www.sciencedirect.com
    Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens
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      DOI: 10.1016/j.celrep.2019.08.038

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  77. www.sciencedirect.com www.sciencedirect.com
    Antibody Conditioning Enables MHC-Mismatched Hematopoietic Stem Cell Transplants and Organ Graft Tolerance
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.stem.2019.05.018

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  78. www.sciencedirect.com www.sciencedirect.com
    Oncolytic Viruses Engineered to Enforce Leptin Expression, Reprogram Tumor-Infiltrating T Cell Metabolism, and Promote Tumor Clearance
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    1. scibot 13 Jan 2020
      RRID:AB_10950145

      DOI: 10.1016/j.immuni.2019.07.003

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  79. www.sciencedirect.com www.sciencedirect.com
    A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus
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    1. scibot 13 Jan 2020
      RRID:AB_10950145

      DOI: 10.1016/j.chom.2018.11.011

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  80. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      DOI: 10.1016/j.cell.2019.03.025

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    sciencedirect.com/science/article/pii/S0092867419302879
  81. www.sciencedirect.com www.sciencedirect.com
    Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation
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    1. scibot 12 Jan 2020
      RRID:AB_10950145

      DOI: 10.1016/j.ccell.2019.04.003

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  82. Nov 2018
  83. www.sciencedirect.com www.sciencedirect.com
    Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy
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    1. scibot 05 Nov 2018
      RRID:AB_10950145

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1535610818304173
  84. www.sciencedirect.com www.sciencedirect.com
    Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer
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    1. scibot 05 Nov 2018
      RRID:AB_10950145

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    sciencedirect.com/science/article/pii/S1550413118303061