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  1. Last 7 days
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    CDK4/6 inhibition sensitizes intracranial tumors to PD-1 blockade in preclinical models of brain metastasis
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    1. scibot 18 Jul 2024
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      DOI: 10.1158/1078-0432.CCR-23-0433

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  3. Jun 2024
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    Therapeutic potential of co-signaling receptor modulation in hepatitis B
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    Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity
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    1. scibot 04 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114289

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  6. Apr 2024
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    The diversity of inhibitory receptor co-expression patterns of exhausted CD8+ T cells in oropharyngeal carcinoma
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    1. scibot 28 Apr 2024
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    Cancer immunotherapy via synergistic co-activation of myeloid receptors CD40 and Dectin-1
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    1. scibot 24 Apr 2024
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      DOI: 10.1126/sciimmunol.adj5097

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    QDPR deficiency drives immune suppression in pancreatic cancer
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    1. scibot 23 Apr 2024
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  10. Mar 2024
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    Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers
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    1. scibot 15 Mar 2024
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  12. Feb 2024
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    UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity
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    SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
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    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.cell.2024.01.008

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  15. Jan 2024
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    Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer
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    A novel translational PET imaging approach to quantifying abscopal immune activation following targeted radiotherapy and checkpoint blockade.
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    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.ijrobp.2023.12.047

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  18. Dec 2023
  19. www.science.org www.science.org
    Cancer immunotherapy via synergistic coactivation of myeloid receptors CD40 and Dectin-1
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    1. scibot 01 Dec 2023
      RRID:AB_10950184

      DOI: 10.1126/sciimmunol.adj5097

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  20. Sep 2023
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    Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy
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    1. scibot 01 Sep 2023
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      DOI: 10.1016/j.xcrm.2023.101171

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  22. Aug 2023
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    KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells
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    1. scibot 25 Aug 2023
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      DOI: 10.1016/j.ccell.2023.07.002

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    CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity
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    1. scibot 23 Aug 2023
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      DOI: 10.1016/j.celrep.2023.113014

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  25. 52.53.155.43 52.53.155.43
    Membrane-localized neoantigens predict the efficacy of cancer immunotherapy
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    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101145

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    52.53.155.43/9f1a09025b86686c62561e67323b0c82e4153e7b/PIIS2666379123002987-html.html
  26. May 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    18F-FMISO PET Imaging Identifies Hypoxia and Immunosuppressive Tumor Microenvironments and Guides Targeted Evofosfamide Therapy in Tumors Refractory to PD-1 and CTLA-4 Inhibition
    1
    1. scibot 05 May 2023
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      DOI: 10.1158/1078-0432.CCR-21-2394

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    ncbi.nlm.nih.gov/pmc/articles/PMC8776604/
  28. Apr 2023
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    Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy
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      DOI: 10.1158/0008-5472.CAN-21-4025

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    Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
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    Mechanism of inert inflammation in an immune checkpoint blockade-resistant tumor subtype bearing transcription elongation defects
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      DOI: 10.1016/j.celrep.2023.112364

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    sciencedirect.com/science/article/pii/S2211124723003753
  32. Feb 2023
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    Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer
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    Spermine enhances antiviral and anticancer responses by stabilizing DNA binding with the DNA sensor cGAS
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    sciencedirect.com/science/article/pii/S1074761323000110
  35. Jan 2023
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    Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy
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      DOI: 10.1016/j.ccell.2022.12.008

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    sciencedirect.com/science/article/pii/S1535610822005943
  37. May 2022
  38. www.sciencedirect.com www.sciencedirect.com
    Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity
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      DOI: 10.1016/j.ccell.2022.04.004

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    sciencedirect.com/science/article/pii/S1535610822001660
  39. Apr 2022
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    The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade
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    1. scibot 13 Apr 2022
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      DOI: 10.1016/j.immuni.2022.03.007

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    sciencedirect.com/science/article/pii/S1074761322001303
  41. Mar 2022
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    PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade
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    1. scibot 30 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110582

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    sciencedirect.com/science/article/pii/S2211124722003266
  43. Nov 2021
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    Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade
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      DOI: 10.1016/j.celrep.2021.110021

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    sciencedirect.com/science/article/pii/S2211124721015035
  45. Sep 2021
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    Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors
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      DOI: 10.1016/j.cell.2021.08.020

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    sciencedirect.com/science/article/pii/S0092867421009946
  47. Aug 2021
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    Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy
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      DOI: 10.1016/j.ccell.2021.07.023

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    sciencedirect.com/science/article/pii/S1535610821004025
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1016/j.cell.2016.08.069

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    ncbi.nlm.nih.gov/pmc/articles/PMC5088716/
  50. Jul 2021
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    Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4+ T Cells
    1
    1. scibot 31 Jul 2021
      Anti-CTLA-4 9H10

      DOI: 10.1016/j.immuni.2019.12.007

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    sciencedirect.com/science/article/pii/S1074761319305266
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    Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells
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      DOI: 10.1016/j.immuni.2018.11.014

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    sciencedirect.com/science/article/pii/S1074761318305223
  53. www.ebiomedicine.com www.ebiomedicine.com
    Oncolytic Newcastle disease virus expressing a checkpoint inhibitor as a radioenhancing agent for murine melanoma
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      DOI: 10.1016/j.ebiom.2019.10.032

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    ebiomedicine.com/article/S2352-3964(19)30702-9/abstract
  54. Jun 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop
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      DOI: 10.1016/j.cell.2021.05.027

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    sciencedirect.com/science/article/pii/S0092867421006577
  56. Sep 2020
  57. www.sciencedirect.com www.sciencedirect.com
    Protein Kinase A Catalytic Subunit Is a Molecular Switch that Promotes the Pro-tumoral Function of Macrophages
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      DOI: 10.1016/j.celrep.2020.107643

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    sciencedirect.com/science/article/pii/S2211124720305969
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    CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity
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    sciencedirect.com/science/article/pii/S1074761320300893
  59. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses
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      DOI: 10.1016/j.celrep.2020.108080

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    pubmed.ncbi.nlm.nih.gov/32877684/
  60. Jan 2020
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_10950184

      DOI: 10.1016/j.celrep.2019.03.066

      Resource: (Bio X Cell Cat# BE0131, RRID:AB_10950184)

      Curator: @evieth

      SciCrunch record: RRID:AB_10950184

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      RRID:AB_10950184 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6719696/
  62. www.sciencedirect.com www.sciencedirect.com
    The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
    1
    1. scibot 13 Jan 2020
      RRID:AB_10950184

      DOI: 10.1016/j.ccell.2019.06.009

      Resource: (Bio X Cell Cat# BE0131, RRID:AB_10950184)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_10950184

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      RRID:AB_10950184 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819303009
  63. www.sciencedirect.com www.sciencedirect.com
    Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade
    1
    1. scibot 13 Jan 2020
      RRID:AB_10950184

      DOI: 10.1016/j.cell.2019.07.019

      Resource: (Bio X Cell Cat# BE0131, RRID:AB_10950184)

      Curator: @ethanbadger

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      RRID:AB_10950184 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867419307846
  64. www.sciencedirect.com www.sciencedirect.com
    Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy
    1
    1. scibot 13 Jan 2020
      RRID:AB_10950184

      DOI: 10.1016/j.cell.2019.10.029

      Resource: (Bio X Cell Cat# BE0131, RRID:AB_10950184)

      Curator: @ethanbadger

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      RRID:AB_10950184 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867419311791
  65. www.cell.com www.cell.com
    Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies
    1
    1. scibot 13 Jan 2020
      RRID:AB_10950184

      DOI: 10.1016/j.celrep.2019.04.091

      Resource: (Bio X Cell Cat# BE0131, RRID:AB_10950184)

      Curator: @ethanbadger

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      RRID:AB_10950184 RRIDCUR:Validated
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    cell.com/cell-reports/fulltext/S2211-1247(19)30571-6
  66. Nov 2017
  67. www.sciencedirect.com www.sciencedirect.com
    Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade
    1
    1. scibot 08 Nov 2017
      BE0131

      Curator: @Jmenke

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      (Bio X Cell Cat# BE0131, RRID:AB_10950184)

      SciCrunch record: RRID:AB_10950184

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_10950184 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S009286741631594X
  68. www.sciencedirect.com www.sciencedirect.com
    Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade
    1
    1. scibot 08 Nov 2017
      RRID:AB_10950184

      Curator: @Jmenke

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      (Bio X Cell Cat# BE0131, RRID:AB_10950184)

      SciCrunch record: RRID:AB_10950184

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_10950184 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610817302982
  69. www.sciencedirect.com www.sciencedirect.com
    Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
    1
    1. scibot 08 Nov 2017
      Anti-CTLA-4 (clone 9H10)BioXcellCat# BE0131

      Curator: @Jmenke

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      (Bio X Cell Cat# BE0131, RRID:AB_10950184)

      SciCrunch record: RRID:AB_10950184

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      RRID:AB_10950184 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867417308310
  70. www.sciencedirect.com www.sciencedirect.com
    Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
    1
    1. scibot 08 Nov 2017
      AB_10950184

      Curator: @gabimpine

      Resource used:

      (Bio X Cell Cat# BE0131, RRID:AB_10950184)

      SciCrunch record: RRID:AB_10950184

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_10950184 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867416311679