151 Matching Annotations
  1. Last 7 days
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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    1. scibot 14 May 2024
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    sciencedirect.com/science/article/pii/S0092867424004483
  3. May 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages
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    ncbi.nlm.nih.gov/pmc/articles/PMC11022165/
  5. Apr 2024
  6. www.sciencedirect.com www.sciencedirect.com
    DTYMK IS AN ESSENTIAL GENE IN MICE AND HETEROZYGOSITY DOES NOT CAUSE NEURAL TUBE DEFECTS
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    1. scibot 16 Apr 2024
      Cell Signaling, D6A

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    sciencedirect.com/science/article/pii/S0003986124001103
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of RASA2 in predicting radioresistance in lung cancer through regulation of p53
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    1. scibot 11 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11002505/
  8. dx.doi.org dx.doi.org
    β-cell insulin resistance plays a causal role in fat-induced β-cell dysfunction in vitro and in vivo
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      AB_10950489

      DOI: 10.1210/endocr/bqae044

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    dx.doi.org/10.1210/endocr/bqae044
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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    sciencedirect.com/science/article/pii/S2211124724003930
  10. Mar 2024
  11. link.springer.com link.springer.com
    Photoreceptors inhibit pathological retinal angiogenesis through transcriptional regulation of Adam17 via c-Fos
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    1. scibot 15 Mar 2024
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    link.springer.com/article/10.1007/s10456-024-09912-0
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    PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages
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    Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon
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    sciencedirect.com/science/article/pii/S1534580724000765
  14. Feb 2024
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    The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis
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      Cell Signaling TechnologyCat# 8457S

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    Protocol for detecting RBM33-binding sites in HEK293T cells using PAR-CLIP-seq
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    1. scibot 07 Feb 2024
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    sciencedirect.com/science/article/pii/S2666166724000200
  17. Jan 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity
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    1. scibot 19 Jan 2024
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    sciencedirect.com/science/article/pii/S1550413123004679
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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    1. scibot 06 Jan 2024
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    sciencedirect.com/science/article/pii/S1550413123004618
  20. Dec 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinin B1 receptor controls maternal adiponectin levels and influences offspring weight gain
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    1. scibot 07 Dec 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10696114/
  22. www.biorxiv.org www.biorxiv.org
    Together, Neuropilin 1 and Neuropilin 2 direct α5 integrin trafficking through GTPase-activating-protein p120RasGAP in endothelial cells to promote fibronectin fibrillogenesis
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    1. scibot 02 Dec 2023
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      DOI: 10.1101/2023.11.28.568967

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    biorxiv.org/content/10.1101/2023.11.28.568967v1
  23. Nov 2023
  24. www.biorxiv.org www.biorxiv.org
    Hyperactivation of MEK1 in cortical glutamatergic neurons results in projection axon deficits and aberrant motor learning
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      DOI: 10.1101/2023.11.06.565901

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    biorxiv.org/content/10.1101/2023.11.06.565901v2
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
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      DOI: 10.1097/BS9.0000000000000168

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      DOI: 10.1097/BS9.0000000000000168

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    ncbi.nlm.nih.gov/pmc/articles/PMC10629731/
  26. Oct 2023
  27. www.embopress.org www.embopress.org
    The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes
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    1. scibot 20 Oct 2023
      RRID:AB_10950489

      DOI: 10.15252/embr.202356815

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    embopress.org/doi/10.15252/embr.202356815
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling
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      DOI: 10.1038/s41420-023-01674-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10575927/
  29. www.sciencedirect.com www.sciencedirect.com
    Spatiotemporal modeling of chemoresistance evolution in breast tumors uncovers dependencies on SLC38A7 and SLC46A1
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    sciencedirect.com/science/article/pii/S2211124723012032
  30. Sep 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy
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      DOI: 10.1038/s41419-023-06159-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10516902/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overfit deep neural network for predicting drug–target interactions
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    ncbi.nlm.nih.gov/pmc/articles/PMC10480310/
  33. www.nature.com www.nature.com
    A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer
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      DOI: 10.1038/s41467-023-40798-6

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    nature.com/articles/s41467-023-40798-6
  34. Aug 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples
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    sciencedirect.com/science/article/pii/S1550413123002723
  36. 52.53.155.43 52.53.155.43
    The miR-23-27-24 clusters drive lipid-associated macrophage proliferation in obese adipose tissue
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    hGFAP-mediated GLI2 overexpression leads to early death and severe cerebellar malformations with rare tumor formation
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    sciencedirect.com/science/article/pii/S258900422301578X
  38. Jul 2023
  39. www.sciencedirect.com www.sciencedirect.com
    mRNA stability and m6A are major determinants of subcellular mRNA localization in neurons
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      DOI: 10.1016/j.molcel.2023.06.021

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    sciencedirect.com/science/article/pii/S1097276523004689
  40. Jun 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification
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    1. scibot 08 Jun 2023
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      DOI: 10.1021/acs.jproteome.2c00706

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    ncbi.nlm.nih.gov/pmc/articles/PMC10243116/
  42. May 2023
  43. www.sciencedirect.com www.sciencedirect.com
    RBM33 is a unique m6A RNA-binding protein that regulates ALKBH5 demethylase activity and substrate selectivity
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    sciencedirect.com/science/article/pii/S1097276523003349
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    The enteric nervous system relays psychological stress to intestinal inflammation
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      DOI: 10.1016/j.cell.2023.05.001

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    sciencedirect.com/science/article/pii/S0092867423004750
  45. www.sciencedirect.com www.sciencedirect.com
    Enhanced mitochondrial fission inhibits triple-negative breast cancer cell migration through a ROS-dependent mechanism
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      DOI: 10.1016/j.isci.2023.106788

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    sciencedirect.com/science/article/pii/S2589004223008659
  46. www.degruyter.com www.degruyter.com
    Inhibition of heterogeneous nuclear ribonucleoproteins A1 and oxidative stress reduces glycolysis pyruvate kinase M2 in chronic thromboembolic pulmonary hypertension
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      DOI: 10.2478/jtim-2022-0051

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    degruyter.com/document/doi/10.2478/jtim-2022-0051/html
  47. www.imrpress.com www.imrpress.com
    Potential New Therapeutic Approaches for Cisplatin-Resistant Testicular Germ Cell Tumors
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      DOI: 10.31083/j.fbl2708245

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    imrpress.com/journal/FBL/27/8/10.31083/j.fbl2708245
  48. Apr 2023
  49. www.sciencedirect.com www.sciencedirect.com
    The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining
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      DOI: 10.1016/j.molcel.2023.03.017

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    sciencedirect.com/science/article/abs/pii/S1097276523002071
  50. Mar 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway
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      DOI: 10.1016/j.chom.2023.02.002

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    sciencedirect.com/science/article/pii/S1931312823000720
  52. Feb 2023
  53. www.sciencedirect.com www.sciencedirect.com
    Injury primes mutation-bearing astrocytes for dedifferentiation in later life
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      DOI: 10.1016/j.cub.2023.02.013

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    sciencedirect.com/science/article/pii/S0960982223001525
  54. Jan 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation
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    Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging
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  57. Dec 2022
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death
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    Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning
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    The κ-opioid receptor-induced autophagy is implicated in stress-driven synaptic alterations
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  62. Nov 2022
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    Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies
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    Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behavior in colon cancer
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    Endogenous metabolism in endothelial and immune cells generates most of the tissue vitamin B3 (nicotinamide)
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    A protocol to characterize zebrafish LGP2 as a dual regulator of IFN response during viral infection
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    Effects of visual deprivation on remodeling of nodes of Ranvier in optic nerve
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    Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
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    MITF Is Regulated by Redox Signals Controlled by the Selenoprotein Thioredoxin Reductase 1
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    The Citrus Flavonoid Nobiletin Downregulates Angiopoietin-like Protein 3 (ANGPTL3) Expression and Exhibits Lipid-Modulating Effects in Hepatic Cells and Adult Zebrafish Models
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  71. Oct 2022
  72. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease
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    Role for N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 Spike maturation and viral infectivity
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    Obesity caused by an OVOL2 mutation reveals dual roles of OVOL2 in promoting thermogenesis and limiting white adipogenesis
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    Role for <i>N</i>-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 Spike maturation and viral infectivity.
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  76. Sep 2022
  77. www.sciencedirect.com www.sciencedirect.com
    Endothelial caveolin-1 regulates cerebral thrombo-inflammation in acute ischemia/reperfusion injury
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    Glucose promotes regulatory T cell differentiation to maintain intestinal homeostasis
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    Posttranslational S-nitrosylation modification regulates HMGB1 secretion and promotes its proinflammatory and neurodegenerative effects
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    Ceramide induces macrophage migration inhibitory factor -mediated parthanatos in mouse neurons by increasing ROS levels
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    Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
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    Limbal BCAM expression identifies a proliferative progenitor population capable of holoclone formation and corneal differentiation
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  84. Jul 2022
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    Phloretin enhances autophagy by impairing AKT activation and inducing JNK-Beclin-1 pathway activation
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    Methionine metabolism regulates pluripotent stem cell pluripotency and differentiation through zinc mobilization
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  87. Jun 2022
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    Poroptosis: a form of cell death depending on plasma membrane nanopores formation
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    Neuregulin-1/ErbB4 signaling modulate Plasmodium falciparum HRP2-induced damage to brain cortical organoids
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  90. May 2022
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    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
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    Akt pathway activation reduces platelet apoptosis and contributes to the increase of platelet counts in solid tumor patients
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  93. Apr 2022
  94. www.sciencedirect.com www.sciencedirect.com
    Betacellulin promotes tumor development and EGFR mutant lung cancer growth by stimulating the EGFR pathway and suppressing apoptosis
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    Long-term and potent IOP-lowering effect of IκBα-siRNA in a nonhuman primate model of chronic ocular hypertension
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    Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization
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  97. Feb 2022
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    Akt pathway activation reduces platelet apoptosis and contributes to the increase of platelet counts in solid tumor patients
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  99. Nov 2021
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel, ataxic mouse model of ataxia telangiectasia caused by a clinically relevant nonsense mutation
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    6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function
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    Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors
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  103. Oct 2021
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  105. Aug 2021
  106. www.sciencedirect.com www.sciencedirect.com
    Macrophage HIF-2α suppresses NLRP3 inflammasome activation and alleviates insulin resistance
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    RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal
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    Long chain n-3 fatty acids attenuate oncogenic KRas-driven proliferation by altering plasma membrane nanoscale proteolipid composition
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    A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants
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    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
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    Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG
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    Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection
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    Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation
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    IKKε and TBK1 in diffuse large B‐cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF‐κB and IL‐10 signalling
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  158. elifesciences.org elifesciences.org
    Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
    1
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      DOI: 10.7554/eLife.44161

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    elifesciences.org/articles/44161
  159. Jan 2020
  160. academic.oup.com academic.oup.com
    Protein arginine methyltransferase 1 interacts with PGC1α and modulates thermogenic fat activation
    1
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      RRID:AB_10950489

      DOI: 10.1210/en.2019-00504

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    academic.oup.com/endo/article-abstract/160/12/2773/5573983
  161. www.sciencedirect.com www.sciencedirect.com
    TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling
    1
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      RRID:AB_10950489

      DOI: 10.1016/j.celrep.2019.07.086

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    sciencedirect.com/science/article/pii/S2211124719310022
  162. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Murine maternal dietary restriction affects neural Humanin expression and cellular profile
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      DOI: 10.1002/jnr.24568

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24568
  163. www.sciencedirect.com www.sciencedirect.com
    Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway✰
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      RRID:AB_10950489

      DOI: 10.1016/j.ebiom.2019.09.041

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    sciencedirect.com/science/article/pii/S2352396419306541
  164. link.springer.com link.springer.com
    Neutrophil elastase contributes to the pathological vascular permeability characteristic of diabetic retinopathy
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    1. scibot 13 Jan 2020
      RRID:AB_10950489

      DOI: 10.1007/s00125-019-04998-4

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    link.springer.com/article/10.1007/s00125-019-04998-4
  165. www.sciencedirect.com www.sciencedirect.com
    Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons
    1
    1. scibot 13 Jan 2020
      RRID:AB_10950489

      DOI: 10.1016/j.stem.2019.08.013

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    sciencedirect.com/science/article/pii/S1934590919303480
  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
    1
    1. scibot 13 Jan 2020
      RRID:AB_10950489

      DOI: 10.1016/j.celrep.2019.07.031

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    ncbi.nlm.nih.gov/pmc/articles/PMC6711191/
  167. www.sciencedirect.com www.sciencedirect.com
    6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion via Modulation of Glutathione Levels
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    1. scibot 13 Jan 2020
      RRID:AB_10950489

      DOI: 10.1016/j.chembiol.2019.05.006

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    sciencedirect.com/science/article/pii/S2451945619301758
  168. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Passive heat therapy protects against endothelial cell hypoxia‐reoxygenation via effects of elevations in temperature and circulating factors
    1
    1. scibot 13 Jan 2020
      RRID:AB_10950489

      DOI: 10.1113/JP276559

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    physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP276559
  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.7554/eLife.44161

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  170. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_10950489

      DOI: 10.1016/j.cell.2019.03.017

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    sciencedirect.com/science/article/pii/S009286741930279X
  171. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_10950489

      DOI: 10.1016/j.cell.2019.02.029

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    sciencedirect.com/science/article/pii/S0092867419302120
  172. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 13 Jan 2020
      RRID:AB_10950489

      DOI: 10.1016/j.chom.2019.02.015

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    sciencedirect.com/science/article/pii/S1931312819301118
  173. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3‐dependent mechanism in male mice
    1
    1. scibot 12 Jan 2020
      AB_10950489

      DOI: 10.1002/jnr.24397

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    onlinelibrary.wiley.com/doi/full/10.1002/jnr.24397
  174. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_10950489

      DOI: 10.1016/j.celrep.2019.03.056

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    sciencedirect.com/science/article/pii/S2211124719303869
  175. www.nature.com www.nature.com
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      RRID:AB_10950489

      DOI: 10.1038/s41389-019-0124-4

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    nature.com/articles/s41389-019-0124-4
  176. Nov 2018
  177. www.sciencedirect.com www.sciencedirect.com
    Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44
    1
    1. scibot 05 Nov 2018
      RRID:AB_10950489

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1074761318303546
  178. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Long chain n-3 fatty acids attenuate oncogenic KRas-driven proliferation by altering plasma membrane nanoscale proteolipid composition
    1
    1. scibot 05 Nov 2018
      RRID:AB_10950489

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    cancerres.aacrjournals.org/content/78/14/3899
  179. www.sciencedirect.com www.sciencedirect.com
    Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling
    1
    1. scibot 05 Nov 2018
      RRID:AB_10950489

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    sciencedirect.com/science/article/pii/S2211124718312038
  180. www.sciencedirect.com www.sciencedirect.com
    An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses
    1
    1. scibot 05 Nov 2018
      8457T

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    sciencedirect.com/science/article/pii/S1097276518305574
  181. www.sciencedirect.com www.sciencedirect.com
    Mechanism of Allosteric Coupling into and through the Plasma Membrane by EGFR
    1
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    sciencedirect.com/science/article/pii/S2451945618301193
  182. www.sciencedirect.com www.sciencedirect.com
    Adipocyte-derived Lysophosphatidylcholine Activates Adipocyte and Adipose Tissue Macrophage Nod-Like Receptor Protein 3 Inflammasomes Mediating Homocysteine-Induced Insulin Resistance
    1
    1. scibot 05 Nov 2018
      RRID:AB_10950489

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    sciencedirect.com/science/article/pii/S2352396418301506
  183. academic.oup.com academic.oup.com
    Effects of Exposure to the Endocrine-Disrupting Chemical Bisphenol A During Critical Windows of Murine Pituitary Development
    1
    1. scibot 05 Nov 2018
      AB_10950489

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    academic.oup.com/endo/article/159/1/119/4349657
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      RRID:AB_10950489

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    ncbi.nlm.nih.gov/pmc/articles/PMC5731821/
  185. europepmc.org europepmc.org
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    europepmc.org/articles/PMC5731821/
  186. Nov 2017
  187. www.sciencedirect.com www.sciencedirect.com
    Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia
    1
    1. scibot 08 Nov 2017
      AB_10950489

      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S1535610817300636
  188. www.sciencedirect.com www.sciencedirect.com
    Farnesoid X Receptor Regulation of the NLRP3 Inflammasome Underlies Cholestasis-Associated Sepsis
    1
    1. scibot 08 Nov 2017
      AB_10950489

      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S1550413117301584
  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Poly-ADP-Ribosylation Fails to Increase Axonal Regeneration or Improve Functional Recovery after Adult Mammalian CNS Injury
    1
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      AB_10950489

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    ncbi.nlm.nih.gov/pmc/articles/PMC5187389/
  190. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ouabain‐induced changes in MAP kinase phosphorylation in primary culture of rat cerebellar cells
    1
    1. scibot 08 Nov 2017
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      Curator: @gabimpine

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    onlinelibrary.wiley.com/doi/10.1002/cbf.3199/full