59 Matching Annotations
  1. Last 7 days
  2. www.cell.com www.cell.com
    Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver
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    cell.com/cell-reports/abstract/S2211-1247(24)00728-9
  3. Jun 2024
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    The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies
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    sciencedirect.com/science/article/pii/S1074761324002711
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors
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    1. scibot 09 Jun 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148061/
  6. May 2024
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    Mitochondrial RelA empowers mtDNA G-quadruplex formation for hypoxia adaptation in cancer cells
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    sciencedirect.com/science/article/pii/S2451945624001818
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    ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity
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    1. scibot 21 May 2024
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    sciencedirect.com/science/article/pii/S0092867424004513
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    Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
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    sciencedirect.com/science/article/pii/S1934590924001425
  10. Apr 2024
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    Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration
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    1. scibot 19 Apr 2024
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    sciencedirect.com/science/article/pii/S221112472400442X
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    Oncostatin M signaling drives cancer-associated skeletal muscle wasting
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    sciencedirect.com/science/article/pii/S2666379124001666
  13. Mar 2024
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    Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon
    2
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    sciencedirect.com/science/article/pii/S1534580724000765
  15. Feb 2024
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    PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity
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    sciencedirect.com/science/article/pii/S2211124724001591
  17. aacrjournals.org aacrjournals.org
    Engagement of CD99 activates distinct programs in Ewing sarcoma and macrophages
    3
    1. scibot 27 Feb 2024
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    aacrjournals.org/cancerimmunolres/article/12/2/247/733768/Engagement-of-CD99-Activates-Distinct-Programs-in
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    The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation
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    sciencedirect.com/science/article/pii/S2211124724001207
  19. Dec 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Apoptosis releases hydrogen sulfide to inhibit Th17 cell differentiation
    1
    1. scibot 19 Dec 2023
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      DOI: 10.1016/j.cmet.2023.11.012

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    sciencedirect.com/science/article/pii/S1550413123004448
  21. Nov 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Gadd45β is critical for regulation of type I interferon signaling by facilitating G3BP-mediated stress granule formation
    1
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  23. Oct 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10575927/
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    High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.xcrm.2023.101214

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    sciencedirect.com/science/article/pii/S2666379123003816
  26. www.embopress.org www.embopress.org
    Immune–epithelial cell cross-talk enhances antiviral responsiveness to SARS-CoV-2 in children
    1
    1. scibot 13 Oct 2023
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      DOI: 10.15252/embr.202357912

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    embopress.org/doi/full/10.15252/embr.202357912
  27. Aug 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Combating pan-coronavirus infection by indomethacin through simultaneously inhibiting viral replication and inflammatory response
    1
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    sciencedirect.com/science/article/pii/S258900422301708X
  29. www.sciencedirect.com www.sciencedirect.com
    Tryptophan metabolism promotes immune evasion in human pancreatic β cells
    1
    1. scibot 03 Aug 2023
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      DOI: 10.1016/j.ebiom.2023.104740

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    sciencedirect.com/science/article/pii/S2352396423003055
  30. Jul 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
    1
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    sciencedirect.com/science/article/pii/S2666379123002483
  32. Jun 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.039

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    sciencedirect.com/science/article/pii/S0092867423005913
  34. www.sciencedirect.com www.sciencedirect.com
    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
    1
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    sciencedirect.com/science/article/pii/S2451945623001502
  35. May 2023
  36. journals.aai.org journals.aai.org
    cGAS Mediates Inflammation by Polarizing Macrophages to M1 Phenotype via the mTORC1 Pathway
    1
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      DOI: 10.4049/jimmunol.2200351

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    journals.aai.org/jimmunol/article/210/8/1098/263495/cGAS-Mediates-Inflammation-by-Polarizing
  37. Mar 2023
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids
    1
    1. scibot 16 Mar 2023
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      DOI: 10.3389/fimmu.2023.1097383

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  39. Dec 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling
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    1. scibot 18 Dec 2022
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    sciencedirect.com/science/article/pii/S2451945622004184
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response
    1
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      DOI: 10.1016/j.isci.2022.105528

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    ncbi.nlm.nih.gov/pmc/articles/PMC9708799/
  42. Nov 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
    1
    1. scibot 05 Nov 2022
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      DOI: 10.1016/j.ebiom.2022.104312

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    sciencedirect.com/science/article/pii/S2352396422004947
  44. Oct 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
    1
    1. scibot 05 Oct 2022
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      DOI: 10.1016/j.celrep.2022.111434

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    sciencedirect.com/science/article/pii/S221112472201275X
  46. Sep 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells
    1
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      DOI: 10.1016/j.neuron.2022.09.002

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    sciencedirect.com/science/article/pii/S0896627322008078
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    SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA
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      DOI: 10.1016/j.molcel.2022.08.031

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    sciencedirect.com/science/article/pii/S1097276522008516
  49. Aug 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-low Induction of Therapy Resistance
    1
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      DOI: 10.1158/1541-7786.MCR-21-0014

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    ncbi.nlm.nih.gov/pmc/articles/PMC8349875/
  51. May 2022
  52. www.sciencedirect.com www.sciencedirect.com
    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
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      DOI: 10.1016/j.immuni.2022.04.006

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    sciencedirect.com/science/article/pii/S1074761322001777
  53. Apr 2022
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular Nicotinamide Phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4
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      DOI: 10.1016/j.isci.2022.104147

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    ncbi.nlm.nih.gov/pmc/articles/PMC8990213/
  55. Mar 2022
  56. www.sciencedirect.com www.sciencedirect.com
    Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense
    1
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      DOI: 10.1016/j.celrep.2022.110549

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    sciencedirect.com/science/article/pii/S221112472200290X
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    Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling
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      DOI: 10.1016/j.molcel.2022.02.007

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    sciencedirect.com/science/article/pii/S1097276522001125
  58. Feb 2022
  59. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction
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      RRID:AB_1095097

      DOI: 10.1016/j.celrep.2022.110420

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    pubmed.ncbi.nlm.nih.gov/35196494/
  60. Jan 2022
  61. www.sciencedirect.com www.sciencedirect.com
    Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses
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      RRID:AB_11220426

      DOI: 10.1016/j.molcel.2021.12.006

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    sciencedirect.com/science/article/pii/S1097276521010686
  62. Oct 2021
  63. www.sciencedirect.com www.sciencedirect.com
    ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
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      DOI: 10.1016/j.celrep.2021.109858

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  64. Aug 2021
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins
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      DOI: 10.7554/eLife.44452

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  66. Jul 2021
  67. www.sciencedirect.com www.sciencedirect.com
    Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING
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    1. scibot 23 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109412

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  68. Jun 2021
  69. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Mutations in the IFNγ-JAK-STAT pathway causing resistance to immune checkpoint inhibitors in melanoma increase sensitivity to oncolytic virus treatment.
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      RRID:AB_10950970

      DOI: 10.1158/1078-0432.CCR-20-3365

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  70. May 2021
  71. academic.oup.com academic.oup.com
    A case of Luscan-Lumish syndrome: Possible involvement of enhanced GH signaling
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      RRID:AB_10950970

      DOI: 10.1210/clinem/dgaa893

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  72. www.sciencedirect.com www.sciencedirect.com
    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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      DOI: 10.1016/j.immuni.2020.06.016

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    sciencedirect.com/science/article/pii/S1074761320302715
  73. Apr 2021
  74. www.sciencedirect.com www.sciencedirect.com
    NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion
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  75. Feb 2021
  76. www.sciencedirect.com www.sciencedirect.com
    microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP
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      DOI: 10.1016/j.molcel.2021.01.030

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  77. www.sciencedirect.com www.sciencedirect.com
    Evasion of type-I interferon by SARS-CoV-2
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      DOI: 10.1016/j.celrep.2020.108234

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  78. Oct 2020
  79. www.sciencedirect.com www.sciencedirect.com
    Evasion of type-I interferon by SARS-CoV-2
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  80. Sep 2020
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-inflammatory, antioxidant and renoprotective effects of SOCS1 mimetic peptide in the BTBR ob/ob mouse model of type 2 diabetes
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      DOI: 10.1136/bmjdrc-2020-001242

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  82. rupress.org rupress.org
    Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex–mediated STAT1 downregulation
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      DOI: 10.1084/jem.20191340

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  83. www.sciencedirect.com www.sciencedirect.com
    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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  84. Jan 2020
  85. www.sciencedirect.com www.sciencedirect.com
    Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
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      RRID:AB_11220426

      DOI: 10.1016/j.immuni.2019.06.007

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  86. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Activation of peroxisome proliferator‐activated receptor delta suppresses BACE1 expression by up‐regulating SOCS1 in a JAK2/STAT1‐dependent manner
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      RRID:AB_10950970

      DOI: 10.1111/jnc.14715

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  87. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions
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    1. scibot 13 Jan 2020
      RRID:AB_10950970

      DOI: 10.1016/j.molcel.2019.07.034

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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      RRID:AB_10950970

      DOI: 10.7554/eLife.41159

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    ncbi.nlm.nih.gov/pmc/articles/PMC6389286/
  89. Nov 2018
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Efficacy of the Interferon Alpha/Beta Response versus Arboviruses Is Temperature Dependent
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    ncbi.nlm.nih.gov/pmc/articles/PMC5915735/
  91. europepmc.org europepmc.org
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