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    MAPK14/p38α shapes the molecular landscape of endometrial cancer and promotes tumorigenic characteristics
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  3. Aug 2024
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    Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression
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    TCF19 Impacts a Network of Inflammatory and DNA Damage Response Genes in the Pancreatic β-Cell
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  6. Jul 2024
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    A human commensal-pathogenic fungus suppresses host immunity via targeting TBK1
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    Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver
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    cell.com/cell-reports/abstract/S2211-1247(24)00728-9
  9. Jun 2024
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    The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies
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    An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors
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  12. May 2024
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    Mitochondrial RelA empowers mtDNA G-quadruplex formation for hypoxia adaptation in cancer cells
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    ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity
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    Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
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  16. Apr 2024
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    Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration
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    Oncostatin M signaling drives cancer-associated skeletal muscle wasting
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  19. Mar 2024
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    Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon
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  21. Feb 2024
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    PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity
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    Engagement of CD99 activates distinct programs in Ewing sarcoma and macrophages
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    The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation
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  25. Dec 2023
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    Apoptosis releases hydrogen sulfide to inhibit Th17 cell differentiation
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  27. Nov 2023
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    Gadd45β is critical for regulation of type I interferon signaling by facilitating G3BP-mediated stress granule formation
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  29. Oct 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling
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    High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
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    Immune–epithelial cell cross-talk enhances antiviral responsiveness to SARS-CoV-2 in children
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  33. Aug 2023
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    Combating pan-coronavirus infection by indomethacin through simultaneously inhibiting viral replication and inflammatory response
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    Tryptophan metabolism promotes immune evasion in human pancreatic β cells
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  36. Jul 2023
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    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
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  38. Jun 2023
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    Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity
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    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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  41. May 2023
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    cGAS Mediates Inflammation by Polarizing Macrophages to M1 Phenotype via the mTORC1 Pathway
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    journals.aai.org/jimmunol/article/210/8/1098/263495/cGAS-Mediates-Inflammation-by-Polarizing
  43. Mar 2023
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    Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids
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  45. Dec 2022
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    Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling
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    Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response
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  48. Nov 2022
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    Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
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  50. Oct 2022
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    Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
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    sciencedirect.com/science/article/pii/S221112472201275X
  52. Sep 2022
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    Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells
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    sciencedirect.com/science/article/pii/S0896627322008078
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    SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA
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  55. Aug 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-low Induction of Therapy Resistance
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      DOI: 10.1158/1541-7786.MCR-21-0014

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    ncbi.nlm.nih.gov/pmc/articles/PMC8349875/
  57. May 2022
  58. www.sciencedirect.com www.sciencedirect.com
    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
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    sciencedirect.com/science/article/pii/S1074761322001777
  59. Apr 2022
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular Nicotinamide Phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4
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    ncbi.nlm.nih.gov/pmc/articles/PMC8990213/
  61. Mar 2022
  62. www.sciencedirect.com www.sciencedirect.com
    Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense
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  63. www.sciencedirect.com www.sciencedirect.com
    Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling
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  64. Feb 2022
  65. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction
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      DOI: 10.1016/j.celrep.2022.110420

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  66. Jan 2022
  67. www.sciencedirect.com www.sciencedirect.com
    Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses
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  68. Oct 2021
  69. www.sciencedirect.com www.sciencedirect.com
    ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
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      DOI: 10.1016/j.celrep.2021.109858

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  70. Aug 2021
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins
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      DOI: 10.7554/eLife.44452

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  72. Jul 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING
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    1. scibot 23 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109412

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  74. Jun 2021
  75. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Mutations in the IFNγ-JAK-STAT pathway causing resistance to immune checkpoint inhibitors in melanoma increase sensitivity to oncolytic virus treatment.
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      DOI: 10.1158/1078-0432.CCR-20-3365

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  76. May 2021
  77. academic.oup.com academic.oup.com
    A case of Luscan-Lumish syndrome: Possible involvement of enhanced GH signaling
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      DOI: 10.1210/clinem/dgaa893

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  78. www.sciencedirect.com www.sciencedirect.com
    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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      DOI: 10.1016/j.immuni.2020.06.016

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    sciencedirect.com/science/article/pii/S1074761320302715
  79. Apr 2021
  80. www.sciencedirect.com www.sciencedirect.com
    NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion
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      DOI: 10.1016/j.cmet.2020.10.021

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  81. Feb 2021
  82. www.sciencedirect.com www.sciencedirect.com
    microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP
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  83. www.sciencedirect.com www.sciencedirect.com
    Evasion of type-I interferon by SARS-CoV-2
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      DOI: 10.1016/j.celrep.2020.108234

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  84. Oct 2020
  85. www.sciencedirect.com www.sciencedirect.com
    Evasion of type-I interferon by SARS-CoV-2
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  86. Sep 2020
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-inflammatory, antioxidant and renoprotective effects of SOCS1 mimetic peptide in the BTBR ob/ob mouse model of type 2 diabetes
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      DOI: 10.1136/bmjdrc-2020-001242

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  88. rupress.org rupress.org
    Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex–mediated STAT1 downregulation
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      DOI: 10.1084/jem.20191340

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  89. www.sciencedirect.com www.sciencedirect.com
    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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      DOI: 10.1016/j.cell.2020.03.040

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  90. Jan 2020
  91. www.sciencedirect.com www.sciencedirect.com
    Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
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      RRID:AB_11220426

      DOI: 10.1016/j.immuni.2019.06.007

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  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Activation of peroxisome proliferator‐activated receptor delta suppresses BACE1 expression by up‐regulating SOCS1 in a JAK2/STAT1‐dependent manner
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      RRID:AB_10950970

      DOI: 10.1111/jnc.14715

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  93. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions
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    1. scibot 13 Jan 2020
      RRID:AB_10950970

      DOI: 10.1016/j.molcel.2019.07.034

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    sciencedirect.com/science/article/pii/S1097276519305891
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      RRID:AB_10950970

      DOI: 10.7554/eLife.41159

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    ncbi.nlm.nih.gov/pmc/articles/PMC6389286/
  95. Nov 2018
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Efficacy of the Interferon Alpha/Beta Response versus Arboviruses Is Temperature Dependent
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  97. europepmc.org europepmc.org
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