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CDK2 inhibition enhances CDK4/6 inhibitor antitumor activity in comprehensive breast cancer PDX model screen

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1. scibot 06 Dec 2025
  
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  DOI: 10.1038/s41523-025-00851-7
  
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2. scibot 06 Dec 2025
  
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  DOI: 10.1038/s41523-025-00851-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12675586/
Oct 2025
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Circadian clock control of ribosome composition promotes rhythmic translation and termination fidelity

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1. scibot 29 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116484
  
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sciencedirect.com/science/article/pii/S2211124725012550
Sep 2025
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2025.08.28.672006v1.full-html.html

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1. scibot 03 Sep 2025
  
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  DOI: 10.1101/2025.08.28.672006
  
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52.53.155.43/1c78deaa12ef1065bee04217bb87fcbf90d61c87/2025.08.28.672006v1.full-html.html
Aug 2025
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A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.molcel.2025.08.001
  
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YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116188
  
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Jul 2025
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Site-resolved assessment of targeted protein degradation

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  DOI: 10.1016/j.chembiol.2025.06.002
  
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Jun 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225012350-main-html.html

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112974
  
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52.53.155.43/228d953e40f5f86c117ef6fb37cbe8e1321da898/1-s2.0-S2589004225012350-main-html.html
Apr 2025
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Profiling the Activity of the Potent and Highly Selective CDK2 Inhibitor BLU-222 Reveals Determinants of Response in CCNE1-Aberrant Ovarian and Endometrial Tumors

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1. scibot 05 Apr 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2360
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11967718/
Dec 2024
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The cGAS-STING pathway activates transcription factor TFEB to stimulate lysosome biogenesis and pathogen clearance

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1. scibot 17 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.017
  
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sciencedirect.com/science/article/pii/S1074761324005326
Apr 2024
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Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner

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1. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114149
  
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sciencedirect.com/science/article/pii/S2211124724004777
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A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation

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1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114024
  
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sciencedirect.com/science/article/pii/S2211124724003528
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Search for Chromosomal Instability aiding Variants (CIVa) reveal naturally occurring kinetochore gene variants that perturb chromosome segregation

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1. scibot 18 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109007
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10867425/
Dec 2023
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The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases

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1. scibot 20 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113581
  
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sciencedirect.com/science/article/pii/S2211124723015930
Oct 2023
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Absence of Embigin accelerates hearing loss and causes sub-viability, brain and cardiac defects in C57BL/6N mice due to interaction with Cdh23ahl

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.108056
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10579432/
May 2023
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Metamorphic proteins at the basis of human autophagy initiation and lipid transfer

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1. scibot 20 May 2023
  
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  DOI: 10.1016/j.molcel.2023.04.026
  
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sciencedirect.com/science/article/pii/S1097276523003210
Dec 2022
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Bidirectional promoter activity from expression cassettes can drive off-target repression of neighboring gene translation

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1. scibot 17 Dec 2022
  
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  DOI: 10.7554/eLife.81086
  
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2. scibot 17 Dec 2022
  
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  DOI: 10.7554/eLife.81086
  
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elifesciences.org/articles/81086
Jun 2022
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Deletion of the Sodium-Dependent Glutamate Transporter GLT-1 in Maturing Oligodendrocytes Attenuates Myelination of Callosal Axons During a Postnatal Phase of Central Nervous System Development

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1. scibot 22 Jun 2022
  
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  DOI: 10.3389/fncel.2022.905299
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9203689/
Apr 2022
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Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock

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1. scibot 14 Apr 2022
  
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  DOI: 10.1016/j.ydbio.2022.04.004
  
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sciencedirect.com/science/article/pii/S0012160622000653
Feb 2022
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LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function

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1. scibot 12 Feb 2022
  
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  DOI: 10.15252/embj.2021108119
  
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embopress.org/doi/abs/10.15252/embj.2021108119
Oct 2021
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Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation

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1. scibot 27 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109899
  
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sciencedirect.com/science/article/pii/S2211124721013693
Aug 2021
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Severe deficiency of the voltage-gated sodium channel NaV1.2 elevates neuronal excitability in adult mice

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1. scibot 15 Aug 2021
  
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  DOI: 10.1016/j.celrep.2021.109495
  
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sciencedirect.com/science/article/pii/S2211124721009220
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Untitled document

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  DOI: 10.1210/en.2017-00677
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5761600/
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Untitled document

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  DOI: 10.1016/j.nbd.2017.09.003
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5675773/
Jul 2021
academic.oup.com academic.oup.com

Menin Associates with the Mitotic Spindle and is Important for Cell Division

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  DOI: 10.1210/en.2019-00274
  
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academic.oup.com/endo/article/160/8/1926/5519300
Jun 2021
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Pumilio2 and Staufen2 selectively balance the synaptic proteome

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  DOI: 10.1016/j.celrep.2021.109279
  
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ZFP36L1 plays an ambiguous role in the regulation of cell expansion and negatively regulates CDKN1A in chronic myeloid leukemia cells

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1. scibot 09 Jun 2021
  
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  DOI: 10.1016/j.exphem.2021.05.006
  
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sciencedirect.com/science/article/pii/S0301472X21001995
May 2021
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The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer

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  DOI: 10.1016/j.cell.2021.04.022
  
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sciencedirect.com/science/article/pii/S009286742100502X
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PIWI proteomics identifies Atari and Pasilla as piRNA biogenesis factors in Aedes mosquitoes

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  DOI: 10.1016/j.celrep.2021.109073
  
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sciencedirect.com/science/article/pii/S2211124721004046
Apr 2021
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Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy

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1. scibot 24 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.06.014
  
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sciencedirect.com/science/article/pii/S0092867420307455
Dec 2020
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IFI16 knockdown in primary HIV-1 target cells

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1. scibot 22 Dec 2020
  
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  DOI: 10.1016/j.xpro.2020.100236
  
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sciencedirect.com/science/article/pii/S2666166720302239
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Rrp6 Moonlights in an RNA Exosome-Independent Manner to Promote Cell Survival and Gene Expression during Stress

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107754
  
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pubmed.ncbi.nlm.nih.gov/32521279/
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Tuba8 Drives Differentiation of Cortical Radial Glia into Apical Intermediate Progenitors by Tuning Modifications of Tubulin C Termini

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1. scibot 15 Sep 2020
  
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  DOI: 10.1016/j.devcel.2020.01.036
  
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sciencedirect.com/science/article/pii/S153458072030068X
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Translation Initiation Site Profiling Reveals Widespread Synthesis of Non-AUG-Initiated Protein Isoforms in Yeast

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1. scibot 09 Sep 2020
  
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Molecular determinants in Frizzled, Reck, and Wnt7a for ligand-specific signaling in neurovascular development

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An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State

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The Ciliary Machinery Is Repurposed for T Cell Immune Synapse Trafficking of LCK

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Global Proteome Remodeling during ER Stress Involves Hac1-Driven Expression of Long Undecoded Transcript Isoforms

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Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation

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Glial overexpression of Dube3a causes seizures and synaptic impairments in Drosophila concomitant with down regulation of the Na+/K+ pump ATPα

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The novel SH3 domain protein Dlish/CG10933 mediates fat signaling in Drosophila by binding and regulating Dachs

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