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The E3 ligase RNF32 controls the IκB kinase complex and NF-κB signaling in intestinal stem cells

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1. scibot 30 Oct 2025
  
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  DOI: 10.1016/j.molcel.2025.10.005
  
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sciencedirect.com/science/article/pii/S1097276525008226
Oct 2025
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Valence and avidity determine the agonistic activity of anti-TNFR2 nanobody fusion proteins

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1. scibot 01 Oct 2025
  
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  DOI: 10.1016/j.chembiol.2025.09.002
  
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sciencedirect.com/science/article/pii/S2451945625002673
Sep 2025
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Ubiquitination-activated TAB–TAK1–IKK–NF-κB axis modulates gene expression for cell survival in the lysosomal damage response

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1. scibot 27 Sep 2025
  
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  DOI: 10.7554/eLife.106901
  
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Sigma-1 receptor counteracts non-cell-autonomous poly-PR-induced astrocytic oxidative stress in C9orf72 ALS

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1. scibot 23 Sep 2025
  
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  DOI: 10.1016/j.redox.2025.103875
  
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sciencedirect.com/science/article/pii/S221323172500388X
Aug 2025
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Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression

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1. scibot 08 Aug 2025
  
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sciencedirect.com/science/article/pii/S1535610825003186
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1-s2.0-S2589004225015664-main-html.html

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1. scibot 07 Aug 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12396248/
Jun 2025
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RNA polymerase II subunit 5-mediating protein limits TLR4-induced innate immune activation in macrophages by inhibiting IKKβ/NF-κB signaling during sepsis

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1. scibot 12 Jun 2025
  
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  DOI: 10.1186/s12964-025-02278-w
  
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link.springer.com/article/10.1186/s12964-025-02278-w
May 2025
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Microbiota-derived urocanic acid triggered bytyrosine kinase inhibitors potentiates cancer immunotherapy efficacy

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.chom.2025.04.022
  
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sciencedirect.com/science/article/pii/S1931312825001556
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NANS suppresses NF-κB signaling to promote ferroptosis by perturbing iron homeostasis

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115701
  
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sciencedirect.com/science/article/pii/S2211124725004723
Apr 2025
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NF-κB signaling directs a program of transient amplifications at innate immune response genes

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1. scibot 18 Apr 2025
  
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  DOI: 10.1101/2025.03.11.641929
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11952383/
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Co-targeting BMI1 and MYC to eliminate cancer stem cells in squamous cell carcinoma

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1. scibot 18 Apr 2025
  
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  DOI: 10.1016/j.xcrm.2025.102077
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12147845/
Mar 2025
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Macrophage-specific PHGDH protects against MAFLD by suppressing TAK1

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115426
  
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sciencedirect.com/science/article/pii/S2211124725001974
Jan 2025
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Anandamide Inhibits Vascular Smooth Muscle Migration, Endothelial Adhesion Protein Expression and Monocyte Adhesion of Human Coronary Artery Cells

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1. scibot 24 Jan 2025
  
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  DOI: 10.3390/cells13242108
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11727187/
Oct 2024
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Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer

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1. scibot 09 Oct 2024
  
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  DOI: 10.1016/j.cell.2024.09.024
  
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sciencedirect.com/science/article/pii/S0092867424010729
Aug 2024
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Cordycepin exhibits both antiviral and anti-inflammatory effects against dengue virus infection

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1. scibot 28 Aug 2024
  
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  AB_11024092
  
  DOI: 10.1016/j.isci.2024.110711
  
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sciencedirect.com/science/article/pii/S2589004224019369
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Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence

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1. scibot 23 Aug 2024
  
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  DOI: 10.1016/j.molcel.2024.08.006
  
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sciencedirect.com/science/article/pii/S1097276524006609
May 2024
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A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death

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1. scibot 24 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.025
  
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sciencedirect.com/science/article/pii/S1074761324002309
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IL17A Suppresses IGFBP1 in Human Endometrial Stromal Cells

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1. scibot 03 May 2024
  
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  DOI: 10.3390/reprodmed5020006
  
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mdpi.com/2673-3897/5/2/6
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N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation

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1. scibot 02 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.004
  
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sciencedirect.com/science/article/pii/S1074761324002097
Mar 2024
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Edaravone dexborneol promotes M2 microglia polarization against lipopolysaccharide-induced inflammation via suppressing TLR4/MyD88/NF-κB pathway

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1. scibot 20 Mar 2024
  
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  DOI: 10.1007/s00210-024-03045-3
  
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link.springer.com/article/10.1007/s00210-024-03045-3
Feb 2024
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Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas

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1. scibot 06 Feb 2024
  
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  DOI: 10.1158/2159-8290.CD-22-1401
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
Jan 2024
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CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise

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  DOI: 10.1016/j.celrep.2023.113626
  
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sciencedirect.com/science/article/pii/S2211124723016376
Nov 2023
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Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins

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1. scibot 11 Nov 2023
  
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  DOI: 10.1097/BS9.0000000000000168
  
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  DOI: 10.1097/BS9.0000000000000168
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10629731/
Oct 2023
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Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells

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1. scibot 18 Oct 2023
  
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  DOI: 10.3390/cells12192389
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10571842/
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15-keto-PGE2 Alleviates Nonalcoholic Steatohepatitis through its Covalent Modification of NF-κB Factors

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1. scibot 06 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.107997
  
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cell.com/iscience/abstract/S2589-0042(23)02074-6
Aug 2023
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IRP1 Mediated Ferroptosis Reverses Temozolomide Resistance in Glioblastoma via Affecting LCN2/FPN1 Signaling Axis Depended on NFKB2

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1. scibot 01 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107377
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10374607/
Jun 2023
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Sublethal necroptosis signaling promotes inflammation and liver cancer

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1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.immuni.2023.05.017
  
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sciencedirect.com/science/article/pii/S1074761323002340
Apr 2023
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Combating breast cancer progression through combination therapy with hypomethylating agent and glucocorticoid

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1. scibot 21 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106597
  
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PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1

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1. scibot 08 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112340
  
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sciencedirect.com/science/article/pii/S2211124723003510
Feb 2023
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Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise

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1. scibot 23 Feb 2023
  
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  DOI: 10.1016/j.cmet.2023.01.011
  
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sciencedirect.com/science/article/pii/S1550413123000116
Jan 2023
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Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice

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  DOI: 10.1016/j.isci.2022.105769
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9804112/
Nov 2022
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Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells

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1. scibot 15 Nov 2022
  
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  DOI: 10.1126/sciadv.abn9912
  
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science.org/doi/10.1126/sciadv.abn9912
Oct 2022
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Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation

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1. scibot 26 Oct 2022
  
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  DOI: 10.1016/j.chembiol.2022.10.002
  
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sciencedirect.com/science/article/pii/S2451945622003567
May 2022
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Effects of interleukin 1β on long noncoding RNA and mRNA expression profiles of human synovial fluid derived mesenchymal stem cells

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1. scibot 21 May 2022
  
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  DOI: 10.1038/s41598-022-12190-9
  
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nature.com/articles/s41598-022-12190-9
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Systematic discovery of mutation-directed neo-protein-protein interactions in cancer

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1. scibot 05 May 2022
  
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  DOI: 10.1016/j.cell.2022.04.014
  
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SHP2 allosteric inhibitor TK-453 alleviates psoriasis-like skin inflammation in mice via inhibition of IL-23/Th17 axis

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Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation

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Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses

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A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

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Untitled document

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Curcumin attenuates proangiogenic and proinflammatory factors in human eutopic endometrial stromal cells through the NF‐κB signaling pathway

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Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

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The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation

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N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation

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Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies

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The inflammatory kinase IKKα phosphorylates and stabilizes c-Myc and enhances its activity

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BCR-Induced Ca2+ Signals Dynamically Tune Survival, Metabolic Reprogramming, and Proliferation of Naive B Cells

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Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis

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BPS Publications

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  DOI: 10.1111/bph.14972
  
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Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells

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TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL

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α-Ketoglutarate-Activated NF-κB Signaling Promotes Compensatory Glucose Uptake and Brain Tumor Development

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Untitled document

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TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging

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Human Cytomegalovirus Protein UL31 Inhibits DNA Sensing of cGAS to Mediate Immune Evasion

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Antagonizing peroxisome proliferator‐activated receptor γ facilitates M1‐to‐M2 shift of microglia by enhancing autophagy via the LKB1–AMPK signaling pathway

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Vitamin D Switches BAF Complexes to Protect β Cells

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B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells

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Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation

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