59 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
    1
    1. scibot 10 Dec 2024
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      DOI: 10.1016/j.cell.2024.11.009

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    sciencedirect.com/science/article/pii/S0092867424013266
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    Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells
    1
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      DOI: 10.1016/j.celrep.2024.115023

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    sciencedirect.com/science/article/pii/S2211124724013743
  4. Nov 2024
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    Probiotics and their metabolite spermidine enhance IFN-γ+CD4+ T cell immunity to inhibit hepatitis B virus
    1
    1. scibot 14 Nov 2024
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      DOI: 10.1016/j.xcrm.2024.101822

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    sciencedirect.com/science/article/pii/S2666379124005937
  6. Sep 2024
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    Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.ccell.2024.08.019

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    sciencedirect.com/science/article/pii/S1535610824003180
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    Glioblastoma induces the recruitment and differentiation of dendritic-like “hybrid” neutrophils from skull bone marrow
    1
    1. scibot 10 Sep 2024
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    sciencedirect.com/science/article/pii/S1535610824003076
  9. Aug 2024
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    Malic enzyme 2 maintains metabolic state and anti-tumor immunity of CD8+ T cells
    1
    1. scibot 22 Aug 2024
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      DOI: 10.1016/j.molcel.2024.07.021

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    sciencedirect.com/science/article/pii/S1097276524006191
  11. Jul 2024
  12. www.science.org www.science.org
    Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1126/science.adh4567

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    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
    1
    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.medj.2024.06.002

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    sciencedirect.com/science/article/pii/S2666634024002484
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    Original research: Second-generation checkpoint inhibitors and Treg depletion synergize with a mouse cancer vaccine in accordance with tumor microenvironment characterization
    1
    1. scibot 04 Jul 2024
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      DOI: 10.1136/jitc-2024-008970

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    ncbi.nlm.nih.gov/pmc/articles/PMC11218019/
  15. May 2024
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    Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma
    1
    1. scibot 07 May 2024
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      DOI: 10.1016/j.immuni.2024.04.006

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    sciencedirect.com/science/article/pii/S1074761324002115
  17. Apr 2024
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    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
    2
    1. scibot 18 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114094

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    Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages
    1
    1. scibot 18 Apr 2024
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      DOI: 10.1016/j.immuni.2024.03.020

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    sciencedirect.com/science/article/pii/S1074761324001419
  20. Mar 2024
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    Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer
    1
    1. scibot 15 Mar 2024
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      DOI: 10.1016/j.cell.2024.02.022

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    Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions
    2
    1. scibot 13 Mar 2024
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      DOI: 10.1016/j.immuni.2024.02.014

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    2. scibot 13 Mar 2024
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      DOI: 10.1016/j.immuni.2024.02.014

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  23. Jan 2024
  24. www.sciencedirect.com www.sciencedirect.com
    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
    2
    1. scibot 04 Jan 2024
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      DOI: 10.1016/j.devcel.2023.07.025

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      DOI: 10.1016/j.devcel.2023.07.025

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    sciencedirect.com/science/article/pii/S1534580723003945
  25. Oct 2023
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    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.immuni.2021.02.020

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    sciencedirect.com/science/article/pii/S1074761321000868
  27. Aug 2023
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    KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells
    1
    1. scibot 25 Aug 2023
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      DOI: 10.1016/j.ccell.2023.07.002

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    Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC
    1
    1. scibot 16 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101150

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    sciencedirect.com/science/article/pii/S2666379123003038
  30. May 2023
  31. www.sciencedirect.com www.sciencedirect.com
    YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
    1
    1. scibot 26 May 2023
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      DOI: 10.1016/j.ccell.2023.04.019

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    sciencedirect.com/science/article/pii/S1535610823001630
  32. Apr 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNγ-Secreting Lymphocytes and IL12-Producing Dendritic Cells
    1
    1. scibot 29 Apr 2023
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      DOI: 10.1158/2326-6066.CIR-21-0326

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    ncbi.nlm.nih.gov/pmc/articles/PMC10132467/
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    Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis
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    1. scibot 29 Apr 2023
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      DOI: 10.1016/j.ccell.2023.04.001

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    sciencedirect.com/science/article/pii/S1535610823001174
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    Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy
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    1. scibot 21 Apr 2023
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      DOI: 10.1158/0008-5472.CAN-21-4025

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    ncbi.nlm.nih.gov/pmc/articles/PMC10102850/
  36. Mar 2023
  37. www.sciencedirect.com www.sciencedirect.com
    DNA-damaged podocyte-CD8 T cell crosstalk exacerbates kidney injury by altering DNA methylation
    1
    1. scibot 30 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112302

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    sciencedirect.com/science/article/pii/S2211124723003133
  38. www.biorxiv.org www.biorxiv.org
    Combinatory EHMT and PARP inhibition induces an interferon response and a CD8 T cell-dependent tumor regression in PARP inhibitor-resistant models
    1
    1. scibot 02 Mar 2023
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      DOI: 10.1101/2023.02.23.529773

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    biorxiv.org/content/10.1101/2023.02.23.529773v1
  39. Jan 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Microglia drive transient insult-induced brain injury by chemotactic recruitment of CD8+ T lymphocytes
    1
    1. scibot 05 Jan 2023
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      DOI: 10.1016/j.neuron.2022.12.009

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    sciencedirect.com/science/article/pii/S0896627322010820
  41. Sep 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
    1
    1. scibot 24 Sep 2022
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      DOI: 10.1016/j.ccell.2022.08.016

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    MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer
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    1. scibot 24 Sep 2022
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      DOI: 10.1016/j.ccell.2022.08.015

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    sciencedirect.com/science/article/pii/S1535610822003798
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    Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity
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    1. scibot 13 Sep 2022
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      DOI: 10.1016/j.xcrm.2022.100744

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    sciencedirect.com/science/article/pii/S2666379122002932
  45. Dec 2021
  46. insight.jci.org insight.jci.org
    Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells
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      DOI: 10.1172/jci.insight.151797

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    insight.jci.org/articles/view/151797
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    SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects
    1
    1. scibot 08 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110085

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    Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses
    1
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      DOI: 10.1016/j.cell.2021.11.007

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    sciencedirect.com/science/article/pii/S0092867421013222
  49. Nov 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells
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    1. scibot 24 Nov 2021
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      DOI: 10.1016/j.isci.2021.103348

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    ncbi.nlm.nih.gov/pmc/articles/PMC8593563/
  51. Sep 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Activating a collaborative innate-adaptive immune response to control metastasis
    1
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      DOI: 10.1016/j.ccell.2021.08.005

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    sciencedirect.com/science/article/pii/S1535610821004451
  53. Aug 2021
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 11 Aug 2021
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      DOI: 10.1016/j.immuni.2017.11.003

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    ncbi.nlm.nih.gov/pmc/articles/PMC5759774/
  55. Jul 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
    1
    1. scibot 30 Jul 2021
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      DOI: 10.1016/j.cell.2018.10.038

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    sciencedirect.com/science/article/pii/S0092867418313941
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      DOI: 10.1016/j.immuni.2018.10.009

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    sciencedirect.com/science/article/pii/S1074761318304746
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    1. scibot 28 Jul 2021
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      DOI: 10.1016/j.immuni.2018.09.024

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    sciencedirect.com/science/article/pii/S1074761318304394
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    Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity
    2
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      DOI: 10.1016/j.cell.2017.05.005

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    2. scibot 28 Jul 2021
      AB_1107671

      DOI: 10.1016/j.cell.2017.05.005

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      Curator: @gabimpine

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      RRID:AB_1107671 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867417305329
  60. May 2021
  61. www.sciencedirect.com www.sciencedirect.com
    A vaccine inducing solely cytotoxic T lymphocytes fully prevents Zika virus infection and fetal damage
    1
    1. scibot 12 May 2021
      RRID:AB_1107671

      DOI: 10.1016/j.celrep.2021.109107

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    sciencedirect.com/science/article/pii/S2211124721004411
  62. Apr 2021
  63. www.sciencedirect.com www.sciencedirect.com
    NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion
    1
    1. scibot 30 Apr 2021
      RRID:AB_1107671

      DOI: 10.1016/j.cmet.2020.10.021

      Resource: (Bio X Cell Cat# BE0004-1, RRID:AB_1107671)

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    sciencedirect.com/science/article/pii/S1550413120305544
  64. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
    1
    1. scibot 02 Apr 2021
      RRID:AB_1107671

      DOI: 10.1016/j.immuni.2021.02.020

      Resource: (Bio X Cell Cat# BE0004-1, RRID:AB_1107671)

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    sciencedirect.com/science/article/pii/S1074761321000868
  65. Feb 2021
  66. www.cell.com www.cell.com
    Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses
    1
    1. scibot 27 Feb 2021
      RRID:AB_1107671

      DOI: 10.1016/j.immuni.2020.09.001

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    cell.com/immunity/abstract/S1074-7613(20)30395-2
  67. Sep 2020
  68. www.sciencedirect.com www.sciencedirect.com
    The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling
    1
    1. scibot 23 Sep 2020
      RRID:AB_1107671

      DOI: 10.1016/j.immuni.2020.03.004

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    sciencedirect.com/science/article/pii/S1074761320301175
  69. www.cell.com www.cell.com
    Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction
    1
    1. scibot 17 Sep 2020
      RRID:AB_1107671

      DOI: 10.1016/j.immuni.2017.11.003

      Resource: (Bio X Cell Cat# BE0004-1, RRID:AB_1107671)

      Curator: @evieth

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    cell.com/immunity/abstract/S1074-7613(17)30480-6
  70. www.sciencedirect.com www.sciencedirect.com
    Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma
    1
    1. scibot 08 Sep 2020
      RRID:AB_1107671

      DOI: 10.1016/j.ccell.2020.03.016

      Resource: (Bio X Cell Cat# BE0004-1, RRID:AB_1107671)

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    sciencedirect.com/science/article/pii/S1535610820301562
  71. www.sciencedirect.com www.sciencedirect.com
    Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP
    1
    1. scibot 03 Sep 2020
      RRID:AB_1107671

      DOI: 10.1016/j.immuni.2020.01.014

      Resource: (Bio X Cell Cat# BE0004-1, RRID:AB_1107671)

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    sciencedirect.com/science/article/pii/S107476132030042X
  72. Jan 2020
  73. www.sciencedirect.com www.sciencedirect.com
    Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment
    1
    1. scibot 13 Jan 2020
      RRID:AB_1107671

      DOI: 10.1016/j.celrep.2019.08.095

      Resource: (Bio X Cell Cat# BE0004-1, RRID:AB_1107671)

      Curator: @ethanbadger

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      RRID:AB_1107671 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S221112471931157X
  74. www.sciencedirect.com www.sciencedirect.com
    B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_1107671

      DOI: 10.1016/j.cell.2019.10.028

      Resource: (Bio X Cell Cat# BE0004-1, RRID:AB_1107671)

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    sciencedirect.com/science/article/pii/S009286741931178X
  75. www.sciencedirect.com www.sciencedirect.com
    Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ
    1
    1. scibot 13 Jan 2020
      RRID:AB_1107671

      DOI: 10.1016/j.immuni.2019.06.017

      Resource: (Bio X Cell Cat# BE0004-1, RRID:AB_1107671)

      Curator: @ethanbadger

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      RRID:AB_1107671 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761319302870
  76. www.sciencedirect.com www.sciencedirect.com
    RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_1107671

      DOI: 10.1016/j.ccell.2018.10.006

      Resource: (Bio X Cell Cat# BE0004-1, RRID:AB_1107671)

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1535610818304720
  77. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 12 Jan 2020
      RRID:AB_1107671

      DOI: 10.1016/j.immuni.2019.01.010

      Resource: (Bio X Cell Cat# BE0004-1, RRID:AB_1107671)

      Curator: @ethanbadger

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      RRID:AB_1107671 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761319300330
  78. Nov 2018
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
    1
    1. scibot 05 Nov 2018
      RRID:AB_1107671

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    ncbi.nlm.nih.gov/pmc/articles/PMC6775781/
  80. www.sciencedirect.com www.sciencedirect.com
    Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance
    1
    1. scibot 05 Nov 2018
      RRID:AB_1107671

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      (Bio X Cell Cat# BE0004-1, RRID:AB_1107671)

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    sciencedirect.com/science/article/pii/S1550413118301207
  81. www.sciencedirect.com www.sciencedirect.com
    Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction
    1
    1. scibot 05 Nov 2018
      RRID:AB_1107671

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      (Bio X Cell Cat# BE0004-1, RRID:AB_1107671)

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    sciencedirect.com/science/article/pii/S1074761317304806
  82. Nov 2017
  83. www.sciencedirect.com www.sciencedirect.com
    The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression
    1
    1. scibot 08 Nov 2017
      BP0004-1

      Curator: @Jmenke

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      (Bio X Cell Cat# BE0004-1, RRID:AB_1107671)

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      RRID:AB_1107671 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1074761317303278