99 Matching Annotations
  1. May 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng
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    1. scibot 31 May 2024
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    2. scibot 31 May 2024
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    sciencedirect.com/science/article/pii/S1074761324002590
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    Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy
    1
    1. scibot 17 May 2024
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    sciencedirect.com/science/article/pii/S1535610824001351
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    The histone lysine methyltransferase MLL1 regulates the activation and functional specialization of regulatory T cells
    1
    1. scibot 14 May 2024
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      DOI: 10.1016/j.celrep.2024.114222

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    sciencedirect.com/science/article/pii/S2211124724005503
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    A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification
    1
    1. scibot 02 May 2024
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    sciencedirect.com/science/article/pii/S1074761324002127
  6. Apr 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
    2
    1. scibot 18 Apr 2024
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    2. scibot 18 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114094

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    sciencedirect.com/science/article/pii/S2211124724004224
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    Regulation of T helper cell differentiation by the interplay between histone modification and chromatin interaction
    1
    1. scibot 16 Apr 2024
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      DOI: 10.1016/j.immuni.2024.03.018

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    sciencedirect.com/science/article/pii/S1074761324001390
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    Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection
    1
    1. scibot 09 Apr 2024
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    sciencedirect.com/science/article/pii/S1074761324001377
  10. Mar 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Clinical drug screening reveals clofazimine potentiates the efficacy while reducing the toxicity of anti-PD-1 and CTLA-4 immunotherapy
    2
    1. scibot 22 Mar 2024
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    2. scibot 22 Mar 2024
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      DOI: 10.1016/j.ccell.2024.03.001

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    sciencedirect.com/science/article/pii/S1535610824000801
  12. www.sciencedirect.com www.sciencedirect.com
    Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers
    1
    1. scibot 15 Mar 2024
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    sciencedirect.com/science/article/pii/S1535610824000576
  13. Feb 2024
  14. www.sciencedirect.com www.sciencedirect.com
    The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis
    1
    1. scibot 22 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113824

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    sciencedirect.com/science/article/pii/S2211124724001529
  15. Jan 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Fc-fused IL-7 provides broad antiviral effects against respiratory virus infections through IL-17A-producing pulmonary innate-like T cells
    1
    1. scibot 21 Jan 2024
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      DOI: 10.1016/j.xcrm.2023.101362

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    sciencedirect.com/science/article/pii/S2666379123005797
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    Bispecific dendritic-T cell engager potentiates anti-tumor immunity
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.cell.2023.12.011

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    sciencedirect.com/science/article/pii/S0092867423013430
  18. Dec 2023
  19. www.sciencedirect.com www.sciencedirect.com
    More time to kill: a longer liver stage increases T cell-mediated protection against pre-erythrocytic malaria
    1
    1. scibot 21 Dec 2023
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      DOI: 10.1016/j.isci.2023.108489

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    sciencedirect.com/science/article/pii/S258900422302566X
  20. Nov 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Mice with FVB-derived sequence on chromosome 17 succumb to disseminated virus infection due to aberrant NK cell and T cell responses
    1
    1. scibot 18 Nov 2023
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      DOI: 10.1016/j.isci.2023.108348

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    sciencedirect.com/science/article/pii/S2589004223024252
  22. www.biorxiv.org www.biorxiv.org
    FASlpr gene dosage tunes the extent of lymphoproliferation and T cell differentiation in lupus
    1
    1. scibot 10 Nov 2023
      RRID:AB_1107694

      DOI: 10.1101/2023.11.01.563607

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    biorxiv.org/content/10.1101/2023.11.01.563607v1
  23. Oct 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease
    1
    1. scibot 13 Oct 2023
      RRID:AB_1107694

      DOI: 10.1016/j.xcrm.2023.101236

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    sciencedirect.com/science/article/pii/S2666379123004135
  25. Jul 2023
  26. www.sciencedirect.com www.sciencedirect.com
    A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.xcrm.2023.101113

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    sciencedirect.com/science/article/pii/S2666379123002410
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    A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity
    1
    1. scibot 13 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112813

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    sciencedirect.com/science/article/pii/S2211124723008240
  28. www.sciencedirect.com www.sciencedirect.com
    Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity
    1
    1. scibot 07 Jul 2023
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      DOI: 10.1016/j.cell.2023.06.002

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    sciencedirect.com/science/article/pii/S0092867423006426
  29. Jun 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation
    1
    1. scibot 01 Jun 2023
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    sciencedirect.com/science/article/pii/S1074761323002212
  31. 52.53.155.43 52.53.155.43
    RORψt+CD4+ T cells promote IL-23R-mediated neuronal cell apoptosis in the central nervous system
    1
    1. scibot 01 Jun 2023
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      DOI: 10.1101/2023.04.17.537133

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    52.53.155.43/333ed306ab43198840b04e278f040205d2c57b40/2023.04.17.537133v1.full-html.html
  32. www.nature.com www.nature.com
    Natural killer cells and innate lymphoid cells 1 tune anxiety-like behavior and memory in mice via interferon-γ and acetylcholine
    1
    1. scibot 01 Jun 2023
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      DOI: 10.1038/s41467-023-38899-3

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    nature.com/articles/s41467-023-38899-3
  33. May 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Transcriptional and metabolic programs promote the expansion of follicular helper T cells in lupus-prone mice
    1
    1. scibot 18 May 2023
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      DOI: 10.1016/j.isci.2023.106774

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  35. Apr 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Restraint of IFN-γ expression through a distal silencer CNS–28 for tissue homeostasis
    1
    1. scibot 12 Apr 2023
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    A neutrophil response linked to tumor control in immunotherapy
    1
    1. scibot 04 Apr 2023
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      DOI: 10.1016/j.cell.2023.02.032

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  38. Mar 2023
  39. europepmc.org europepmc.org
    mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy
    1
    1. scibot 22 Mar 2023
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      DOI: 10.1016/j.xcrm.2023.100978

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  40. Jan 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner
    1
    1. scibot 21 Jan 2023
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      DOI: 10.1016/j.celrep.2023.112002

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    Opioid-induced fragile-like regulatory T cells contribute to withdrawal
    1
    1. scibot 21 Jan 2023
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      DOI: 10.1016/j.cell.2022.12.030

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    sciencedirect.com/science/article/pii/S0092867422015732
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    GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology
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    1. scibot 12 Jan 2023
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    Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
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    1. scibot 12 Jan 2023
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    Immunoediting instructs tumor metabolic reprogramming to support immune evasion
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      DOI: 10.1016/j.cmet.2022.12.003

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  46. Nov 2022
  47. www.cell.com www.cell.com
    Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop
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    1. scibot 24 Nov 2022
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    cell.com/cancer-cell/fulltext/S1535-6108(22)00549-9
  48. www.sciencedirect.com www.sciencedirect.com
    The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
    1
    1. scibot 15 Nov 2022
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    sciencedirect.com/science/article/pii/S1074761322005611
  49. Sep 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose promotes regulatory T cell differentiation to maintain intestinal homeostasis
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    1. scibot 21 Sep 2022
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      DOI: 10.1016/j.isci.2022.105004

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    ncbi.nlm.nih.gov/pmc/articles/PMC9460814/
  51. www.sciencedirect.com www.sciencedirect.com
    Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity
    1
    1. scibot 16 Sep 2022
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      DOI: 10.1016/j.ccell.2022.08.014

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    sciencedirect.com/science/article/pii/S1535610822003786
  52. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis
    1
    1. scibot 15 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111328

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    sciencedirect.com/science/article/pii/S2211124722011561
  53. Aug 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis
    1
    1. scibot 23 Aug 2022
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      DOI: 10.1016/j.chom.2022.07.015

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    sciencedirect.com/science/article/pii/S1931312822003614
  55. Jun 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis
    1
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  57. aacrjournals.org aacrjournals.org
    Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function
    1
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      DOI: 10.1158/0008-5472.CAN-21-3155

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  58. May 2022
  59. www.sciencedirect.com www.sciencedirect.com
    Newly recruited intraepithelial Ly6A+CCR9+CD4+ T cells protect against enteric viral infection
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      RRID:AB_1107694

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  60. Apr 2022
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    ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection
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  62. Mar 2022
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    Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites
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  64. Feb 2022
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity
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  66. Jan 2022
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The enteric pathogen Cryptosporidium parvum exports proteins into the cytosol of the infected host cell
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  68. Dec 2021
  69. elifesciences.org elifesciences.org
    IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-γ production by CD25+Foxp3- T cells
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation
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  71. Nov 2021
  72. www.sciencedirect.com www.sciencedirect.com
    Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade
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  73. Oct 2021
  74. www.sciencedirect.com www.sciencedirect.com
    Cold exposure protects from neuroinflammation through immunologic reprogramming
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    Costimulation molecules differentially regulate the ERK-Zfp831 axis to shape T follicular helper cell differentiation
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    Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza
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  77. Aug 2021
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    Delivery of membrane impermeable molecules to primary mouse T lymphocytes
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  79. www.jimmunol.org www.jimmunol.org
    MicroRNA-10a Negatively Regulates CD4+ T Cell IL-10 Production through Suppression of Blimp1
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  80. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.cell.2018.10.014

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  81. www.sciencedirect.com www.sciencedirect.com
    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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      DOI: 10.1016/j.immuni.2018.09.004

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  83. Jul 2021
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    The Transcription Factor Tox2 Drives T Follicular Helper Cell Development via Regulating Chromatin Accessibility
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      Anti-IFNγ (clone XMG1.2)

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      RRID:AB_2783515

      DOI: 10.1016/j.cels.2019.01.001

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    A safe and effective mucosal RSV vaccine in mice consisting of RSV phosphoprotein and flagellin variant
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  89. May 2021
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    Pre-clinical evaluation of a whole-parasite vaccine to control human babesiosis
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    Food colorants metabolized by commensal bacteria promote colitis in mice with dysregulated expression of interleukin-23
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    Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses
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    Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells
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    Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium
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    The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation
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    Adoptive T Cell Therapy Targeting Different Gene Products Reveals Diverse and Context-Dependent Immune Evasion in Melanoma
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
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  98. Apr 2021
  99. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23
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    Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis
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      DOI: 10.1016/j.cell.2020.08.020

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  101. Mar 2021
  102. www.sciencedirect.com www.sciencedirect.com
    Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity
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    sciencedirect.com/science/article/pii/S2211124721001479
  103. Feb 2021
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    The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation
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  105. Dec 2020
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    Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis
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  107. Sep 2020
  108. www.sciencedirect.com www.sciencedirect.com
    Foxo3 Promotes the Differentiation and Function of Follicular Helper T Cells
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    Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics
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    Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis
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    Natural killer cells modulate motor neuron-immune cell cross talk in models of Amyotrophic Lateral Sclerosis
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    nature.com/articles/s41467-020-15644-8
  112. www.sciencedirect.com www.sciencedirect.com
    Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
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      DOI: 10.1016/j.ccell.2020.02.008

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    sciencedirect.com/science/article/pii/S1535610820300970
  113. Jan 2020
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.cell.2019.05.047

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  115. www.sciencedirect.com www.sciencedirect.com
    Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products
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      DOI: 10.1016/j.celrep.2019.10.042

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    sciencedirect.com/science/article/pii/S2211124719313567
  116. www.sciencedirect.com www.sciencedirect.com
    Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease
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      DOI: 10.1016/j.cell.2019.11.026

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    sciencedirect.com/science/article/pii/S0092867419312838
  117. www.sciencedirect.com www.sciencedirect.com
    Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells
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      DOI: 10.1016/j.ccell.2019.10.006

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    sciencedirect.com/science/article/pii/S1535610819304805
  118. www.sciencedirect.com www.sciencedirect.com
    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.07.044

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    sciencedirect.com/science/article/pii/S2211124719309416
  119. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      DOI: 10.1016/j.celrep.2019.01.104

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    sciencedirect.com/science/article/pii/S221112471930141X
  120. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_1107694

      DOI: 10.1016/j.immuni.2018.12.014

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    sciencedirect.com/science/article/pii/S1074761318305624
  121. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 12 Jan 2020
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      DOI: 10.1016/j.immuni.2019.01.003

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    sciencedirect.com/science/article/pii/S1074761319300032
  122. Nov 2018
  123. www.sciencedirect.com www.sciencedirect.com
    Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy
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      Curator: @Jmenke

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  124. www.sciencedirect.com www.sciencedirect.com
    Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells
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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S2211124718314463
  125. elifesciences.org elifesciences.org
    Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation
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    elifesciences.org/articles/36158
  126. www.sciencedirect.com www.sciencedirect.com
    Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production
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    sciencedirect.com/science/article/pii/S1074761318302449
  127. www.sciencedirect.com www.sciencedirect.com
    Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors
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    sciencedirect.com/science/article/pii/S1535610818302186
  128. www.sciencedirect.com www.sciencedirect.com
    TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer
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    sciencedirect.com/science/article/pii/S1535610817305238
  129. www.sciencedirect.com www.sciencedirect.com
    Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment
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    sciencedirect.com/science/article/pii/S1535610817304713
  130. Nov 2017
  131. www.sciencedirect.com www.sciencedirect.com
    Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever
    1
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1931312817302913
  132. www.sciencedirect.com www.sciencedirect.com
    The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells
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      AB_1107694

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1074761317302212