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T cell cross-priming by PD-L1+ type 1 conventional dendritic cells mediates the antitumor efficacy of a PD-L1×4-1BB bispecific antibody

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Oct 2026
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The pyrin inflammasome senses OCTN2-mediated uptake of extracellular ʟ-carnitine from muscle injury or ingestion

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cell.com/cell/abstract/S0092-8674(26)01117-7
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Germinal center interleukin-4 microniches drive tissue divergence of IgE memory B cell responses

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cell.com/immunity/abstract/S1074-7613(26)00350-X
Aug 2026
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Interleukin-17A-producing γδ T cells drive cognitive dysfunction in periodontitis

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The genesis of cutaneous neurogenic inflammation is a multi-step process requiring dendritic cell aggregation

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Dendritic cell circadian clocks shape memory CD8+ T cell differentiation

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  DOI: 10.1126/sciadv.aeh3719
  
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Jul 2026
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Non-canonical NF-κB drives a fate switch from germinal center to early effector B cells

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GABA promotes resistance to immunotherapy in patients with TLS-positive tumors

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Jun 2026
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Plasma signals of lung tumor promotion for molecular cancer prevention

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May 2026
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ST8Sia6-dependent glycosylation restrains gut inflammation and pathogenic Th1 and Th17 programs

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Proteostasis sustains T cell differentiation potential and tumor-infiltrating lymphocyte function

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Apr 2026
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Regulatory T cells poise the myeloid landscape after chemotherapy in lung tumors

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  DOI: 10.1158/2326-6066.CIR-25-0103
  
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aacrjournals.org/cancerimmunolres/article/13/10/1561/765466/Regulatory-T-Cells-Poise-the-Myeloid-Landscape
Feb 2026
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Preoperative exercise induces anti-tumor Kupffer cells to prevent surgical stress-promoted colorectal cancer liver metastasis

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1. scibot 10 Feb 2026
  
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  DOI: 10.1016/j.xcrm.2026.102589
  
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sciencedirect.com/science/article/pii/S2666379126000066
Jan 2026
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Microbiota utilization of intestinal amino acids modulates cancer progression and anticancer immunity

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  DOI: 10.1016/j.chom.2025.12.003
  
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Dec 2025
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Dysplastic epithelial repair promotes the tissue residence of lymphocytes to inhibit alveolar regeneration post viral infection

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  DOI: 10.1016/j.stem.2025.12.005
  
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Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

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  DOI: 10.1016/j.cell.2025.11.023
  
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Dietary restriction reprograms CD8+ T cell fate to enhance anti-tumour immunity and immunotherapy responses

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  DOI: 10.1038/s42255-025-01415-6
  
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nature.com/articles/s42255-025-01415-6
Nov 2025
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IL-1R1-positive dorsal raphe neurons drive self-imposed social withdrawal in sickness

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  DOI: 10.1016/j.cell.2025.10.040
  
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cell.com/cell/fulltext/S0092-8674(25)01245-0
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Mucosal viral infection elicits long-lived IgA responses via type 1 follicular helper T cells

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Sep 2025
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1-s2.0-S2589004225017985-main-html.html

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Aug 2025
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Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells

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Jul 2025
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Adoptively transferred Th17 cells cooperate with host B cells to achieve durable tumor immunity

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May 2025
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IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis

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Age-related impairment of intestinal inflammation resolution through an eicosanoid-immune-microbiota axis

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Macrophages direct location-dependent recall of B cell memory to vaccination

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Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread

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Apr 2025
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ULBP2 Promotes Tumor Progression by Suppressing NKG2D-Mediated Anti-Tumor Immunity

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Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease

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Mar 2025
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PDF-html.html

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  DOI: 10.1158/1535-7163.mct-24-0715
  
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Temporal dynamics of immune cell transcriptomics in brain metastasis progression influenced by gut microbiome dysbiosis

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cell.com/cell-reports/abstract/S2211-1247(25)00127-5
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Splenic TNF-α signaling potentiates the innate-to-adaptive transition of antiviral NK cells

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Feb 2025
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Crosstalk between myeloid and B cells shapes the distinct microenvironments of primary and secondary liver cancer

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  DOI: 10.1158/0008-5472.CAN-23-0193
  
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aacrjournals.org/cancerres/article/83/21/3544/729719/Cross-talk-between-Myeloid-and-B-Cells-Shapes-the
Dec 2024
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BPS Publications

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1. scibot 13 Dec 2024
  
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  DOI: 10.1111/bph.17404
  
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Heightened Innate Immune State Induced by Viral Vector Leads to Enhanced Response to Challenge and Prolongs Malaria Vaccine Protection

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  DOI: 10.1016/j.isci.2024.111468
  
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Nov 2024
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Pericancerous cross-presentation to cytotoxic T lymphocytes impairs immunotherapeutic efficacy in hepatocellular carcinoma

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1. scibot 21 Nov 2024
  
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  DOI: 10.1016/j.ccell.2024.10.012
  
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Probiotics and their metabolite spermidine enhance IFN-γ+CD4+ T cell immunity to inhibit hepatitis B virus

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T cells regulate intestinal motility and shape enteric neuronal responses to intestinal microbiota.

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Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function

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Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages

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Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection

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An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade

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An axon-T cell feedback loop enhances inflammation and axon degeneration

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DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic vulnerabilities

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Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation

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KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells

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PIIS2211124723009622-html.html

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CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells

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Synergism Between IL21 and Anti-PD-1 Combination Therapy is Underpinned by the Coordinated Reprogramming of the Immune Cellular Network in the Tumor Microenvironment

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can-23-0193-html.html

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Jul 2023
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Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses

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Jun 2023
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Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses

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STAT3 signaling in B cells controls germinal center zone organization and recycling

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Immune mechanisms shape the clonal landscape during early progression of prostate cancer

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The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries

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Galectin-3 expression in donor T cells reduces GvHD severity and lethality after allogeneic hematopoietic cell transplantation

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Thymus Antibody-Secreting Cells Possess an Interferon Gene Signature and are Preferentially Expanded in Young Female Mice

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Feb 2023
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IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment

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Neutrophil-activating therapy for the treatment of cancer

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GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology

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Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma

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Microglia drive transient insult-induced brain injury by chemotactic recruitment of CD8+ T lymphocytes

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Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells

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STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation

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Obesity enhances antiviral immunity in the genital mucosa through a microbiota-mediated effect on γδ T cells

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Neuropilin-1 cooperates with PD-1 in CD8+ T-cells predicting outcomes in melanoma patients treated with anti-PD1

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The C5a-C5aR1 complement axis is essential for neutrophil recruitment to draining lymph nodes via high endothelial venules in cutaneous leishmaniasis

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Mycobacterium tuberculosis impedes CD40-dependent notch signaling to restrict Th17 polarization during infection

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Germinal center expansion but not plasmablast differentiation is proportional to peptide-MHCII density via CD40-CD40L signaling strength

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Negative Immune Checkpoint Protein, VISTA, Regulates the CD4+ Treg Population During Sepsis Progression to Promote Acute Sepsis Recovery and Survival

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Mar 2022
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Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa

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Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity

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Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance

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Expeditious recruitment of circulating memory CD8 T cells to the liver facilitates control of malaria

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CXCL10/CXCR3 signaling contributes to an inflammatory microenvironment and its blockade enhances progression of murine pancreatic precancerous lesions

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Untitled document

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Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells

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  InVivoMAb polyclonal Armenian hamster IgG clone N/A
  
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Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity

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Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop

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Dynamic modulation of spleen germinal center reactions by gut bacteria during Plasmodium infection

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Reciprocal communication between astrocytes and endothelial cells is required for astrocytic glutamate transporter 1 (GLT-1) expression

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Apr 2021
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TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate

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Mar 2021
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Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection

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1. scibot 29 Mar 2021
  
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Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation

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Gut Microbiota Composition Modulates the Magnitude and Quality of Germinal Centers during Plasmodium Infections

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Sep 2020
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Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response

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Inflammation-Induced Lactate Leads to Rapid Loss of Hepatic Tissue-Resident NK Cells

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FOXD3 Regulates VISTA Expression in Melanoma

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Jan 2020
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Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells

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  DOI: 10.1016/j.cmet.2019.05.016
  
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Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors

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Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity

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Nov 2018
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CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity

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Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

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Staphylococcus aureus Virulent PSMα Peptides Induce Keratinocyte Alarmin Release to Orchestrate IL-17-Dependent Skin Inflammation

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Nov 2017
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Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase

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