85 Matching Annotations
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    Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng
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    1. scibot 31 May 2024
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  3. May 2024
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    Expression of the membrane tetraspanin claudin 18 on cancer cells promotes T lymphocyte infiltration and antitumor immunity in pancreatic cancer
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    1. scibot 16 May 2024
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    sciencedirect.com/science/article/pii/S1074761324002267
  5. Apr 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression
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    1. scibot 03 Apr 2024
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    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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    1. scibot 02 Apr 2024
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  8. Mar 2024
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    Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity
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    1. scibot 27 Mar 2024
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    Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers
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    1. scibot 15 Mar 2024
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  11. Jan 2024
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    Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms
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    1. scibot 19 Jan 2024
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    Skin microbe-dependent TSLP-ILC2 priming axis in early life is co-opted in allergic inflammation
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    sciencedirect.com/science/article/pii/S1931312823005012
  14. Nov 2023
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    A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression
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    1. scibot 17 Nov 2023
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    Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers
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    1. scibot 02 Nov 2023
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  17. Oct 2023
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    Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation
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    1. scibot 28 Oct 2023
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    sciencedirect.com/science/article/pii/S2211124723013359
  19. Sep 2023
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    Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control
    1
    1. scibot 01 Sep 2023
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  21. Jul 2023
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    Lung injury induces a polarized immune response by self-antigen-specific CD4+ Foxp3+ regulatory T cells
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    1. scibot 21 Jul 2023
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    TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation
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    1. scibot 01 Jul 2023
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  24. Jun 2023
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    Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses
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    1. scibot 23 Jun 2023
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    DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs
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    1. scibot 21 Jun 2023
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  27. May 2023
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    Immune mechanisms shape the clonal landscape during early progression of prostate cancer
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    sciencedirect.com/science/article/pii/S1534580723001806
  29. Apr 2023
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    Semi-Supervised Analysis of myeloid and T cell behaviour in ex vivo ovarian tumour slices reveals changes in cell motility after treatments
    1
    1. scibot 23 Apr 2023
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    sciencedirect.com/science/article/pii/S2589004223005916
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    Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir
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    1. scibot 20 Apr 2023
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    sciencedirect.com/science/article/pii/S1074761323000444
  32. Mar 2023
  33. www.biorxiv.org www.biorxiv.org
    “Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression”
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    1. scibot 09 Mar 2023
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      DOI: 10.1101/2023.03.02.529724

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    biorxiv.org/content/10.1101/2023.03.02.529724v1
  34. Feb 2023
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    PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
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  36. Jan 2023
  37. 52.53.155.43 52.53.155.43
    SSRN-id4272137-html.html
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    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis
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    GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology
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    sciencedirect.com/science/article/pii/S1074761322006458
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    Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
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    1. scibot 10 Jan 2023
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  41. Dec 2022
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    IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer
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    1. scibot 17 Dec 2022
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    Cancer cell-derived type I interferons instruct tumor monocyte polarization
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  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity
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      DOI: 10.1136/jitc-2022-004806

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    ncbi.nlm.nih.gov/pmc/articles/PMC9703354/
  45. Sep 2022
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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      DOI: 10.1158/2159-8290.CD-21-1077

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  47. Aug 2022
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
    1
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  49. Jun 2022
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    Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis
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  51. May 2022
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    Newly recruited intraepithelial Ly6A+CCR9+CD4+ T cells protect against enteric viral infection
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    Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity
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  54. Apr 2022
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    Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma
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    sciencedirect.com/science/article/pii/S2211124722004533
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    TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells
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      DOI: 10.1016/j.celrep.2022.110657

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  57. Feb 2022
  58. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction
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    Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy
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  60. Dec 2021
  61. insight.jci.org insight.jci.org
    Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells
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      DOI: 10.1172/jci.insight.151797

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    Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity
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  63. Nov 2021
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    Expeditious recruitment of circulating memory CD8 T cells to the liver facilitates control of malaria
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  65. Oct 2021
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    Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza
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  67. Sep 2021
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    Vaccination induces rapid protection against bacterial pneumonia via training alveolar macrophage in mice
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  69. Aug 2021
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    Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors
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    The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression
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    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
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  78. Jul 2021
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    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
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  85. May 2021
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    Discrete limbal epithelial stem cell populations mediate corneal homeostasis and wound healing
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      InVivoMAb Rat IgG1 Isotype control; anti Horseradish Peroxidase

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    The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake
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    Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy
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    CD276 expression enables squamous cell carcinoma stem cells to evade immune surveillance
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  90. Apr 2021
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    Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis
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  93. Feb 2021
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    Cardiolipin-mediated PPARγ S112 phosphorylation impairs IL-10 production and inflammation resolution during bacterial pneumonia
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  95. Nov 2020
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    MicroRNAs of the miR-17~9 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression
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  97. Oct 2020
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  99. Sep 2020
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    Th1-Th2 Cross-Regulation Controls Early Leishmania Infection in the Skin by Modulating the Size of the Permissive Monocytic Host Cell Reservoir
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    Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues
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  104. Jan 2020
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    Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence
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    Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors
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    Intraperitoneal cancer-immune microenvironment promotes peritoneal dissemination of gastric cancer
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    Lymphocyte Activation Gene-3 Maintains Mitochondrial and Metabolic Quiescence in Naive CD4+ T Cells
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  111. Nov 2018
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    Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution
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    mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis
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    TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer
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      RRID:AB_1107775

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      RRID:AB_1107775
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    sciencedirect.com/science/article/pii/S1535610817305238
  116. europepmc.org europepmc.org
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    1. scibot 05 Nov 2018
      RRID:AB_1107775

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  117. Nov 2017
  118. www.sciencedirect.com www.sciencedirect.com
    Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever
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    1. scibot 08 Nov 2017
      RRID:AB_1107775

      Curator: @Jmenke

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      RRID:AB_1107775 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1931312817302913
  119. europepmc.org europepmc.org
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    europepmc.org/articles/PMC5002269/table/undtbl1/
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      AB_1107775

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  121. www.cell.com www.cell.com
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      AB_1107775

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    cell.com/action/showMethods