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Removal of Interstitial Hyaluronan Facilitates Subcutaneous Administration and Lymphatic Delivery of Anti-CTLA4 and Improves Antitumor Efficacy

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1. scibot 28 Apr 2026
  
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  DOI: 10.1158/2326-6066.CIR-25-0256
  
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aacrjournals.org/cancerimmunolres/article/14/3/450/774856/Removal-of-Interstitial-Hyaluronan-Facilitates
Apr 2026
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Identification of cycling regulatory T cell precursors as conductors of immune escape during breast carcinoma progression

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1. scibot 17 Apr 2026
  
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  DOI: 10.1016/j.ccell.2026.03.015
  
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sciencedirect.com/science/article/pii/S1535610826001698
Mar 2026
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HE4 drives PD-L1 expression in myeloid cells via IFN-γR-JAK-STAT3 signaling to promote tumor immune evasion

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.xcrm.2026.102691
  
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sciencedirect.com/science/article/pii/S2666379126001084
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Kindlin-2-mediated hematopoiesis remodeling regulates triple-negative breast cancer immune evasion

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1. scibot 18 Mar 2026
  
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  DOI: 10.1158/1541-7786.MCR-24-0698
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12977202/
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Transcriptomic profiling of mouse mammary tumors enables prognostic and predictive biomarker discovery for human breast cancers

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1. scibot 12 Mar 2026
  
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  DOI: 10.64898/2026.02.28.707759
  
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biorxiv.org/content/10.64898/2026.02.28.707759v1
Feb 2026
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Immune Stromal Components Impede Biological Effectiveness of Carbon Ion Therapy in a Preclinical Model of Pancreatic Ductal Adenocarcinoma

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1. scibot 07 Feb 2026
  
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  DOI: 10.1158/1535-7163.MCT-25-0501
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12869159/
Jul 2025
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TIM3+ breast cancer cells license immune evasion during micrometastasis outbreak

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.06.015
  
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cell.com/cancer-cell/abstract/S1535-6108(25)00265-X
Jun 2025
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Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade

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1. scibot 04 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102141
  
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sciencedirect.com/science/article/pii/S2666379125002149
May 2025
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Somatic hypermutation unlocks antibody specificities beyond the primary repertoire

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.014
  
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sciencedirect.com/science/article/pii/S1074761325001773
Mar 2025
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Targeting tumor monocyte-intrinsic PD-L1 by rewiring STING signaling and enhancing STING agonist therapy

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.02.014
  
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sciencedirect.com/science/article/pii/S1535610825000662
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IL-17RA signaling provides dual tumor-suppressor function during late-stage colorectal carcinogenesis

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1. scibot 05 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.005
  
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cell.com/immunity/fulltext/S1074-7613(25)00073-1
Feb 2025
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Hyperthermic intrathoracic chemotherapy modulates the immune microenvironment of pleural mesothelioma and improves the impact of dual immune checkpoint inhibition

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1. scibot 20 Feb 2025
  
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  DOI: 10.1158/2326-6066.CIR-24-0245
  
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aacrjournals.org/cancerimmunolres/article/13/2/185/751253/Hyperthermic-Intrathoracic-Chemotherapy-Modulates
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Activation of IL-2/IL-2R pathway by Hedyotis diffusa polysaccharide improves immunotherapy in colorectal cancer

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1. scibot 20 Feb 2025
  
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  RRID:AB_1107791
  
  DOI: 10.1016/j.ijbiomac.2025.141013
  
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sciencedirect.com/science/article/pii/S0141813025015624
Dec 2024
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Stochastic modeling of single-cell gene expression adaptation reveals non-genomic contribution to evolution of tumor subclones

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1. scibot 19 Dec 2024
  
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  RRID:AB_1107791
  
  DOI: 10.1016/j.cels.2024.11.013
  
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sciencedirect.com/science/article/pii/S2405471224003491
May 2024
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ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity

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1. scibot 21 May 2024
  
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  RRID:AB_1107791
  
  DOI: 10.1016/j.cell.2024.04.025
  
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sciencedirect.com/science/article/pii/S0092867424004513
Feb 2024
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Lactate modulates RNA splicing to promote CTLA-4 expression in tumor-infiltrating regulatory T cells

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1. scibot 29 Feb 2024
  
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  RRID:AB_1107791
  
  DOI: 10.1016/j.immuni.2024.01.019
  
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2. scibot 29 Feb 2024
  
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  RRID:AB_1107791
  
  DOI: 10.1016/j.immuni.2024.01.019
  
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sciencedirect.com/science/article/pii/S1074761324000451
Jan 2024
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Skin microbe-dependent TSLP-ILC2 priming axis in early life is co-opted in allergic inflammation

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1. scibot 11 Jan 2024
  
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  RRID:AB_1107791
  
  DOI: 10.1016/j.chom.2023.12.006
  
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sciencedirect.com/science/article/pii/S1931312823005012
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Helicobacter pylori CagA promotes immune evasion of gastric cancer by upregulating PD-L1 level in exosomes

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1. scibot 06 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108414
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10692710/
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The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer

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1. scibot 02 Dec 2023
  
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  DOI: 10.1016/j.immuni.2023.11.002
  
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sciencedirect.com/science/article/pii/S1074761323004831
Nov 2023
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Mice with FVB-derived sequence on chromosome 17 succumb to disseminated virus infection due to aberrant NK cell and T cell responses

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1. scibot 18 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108348
  
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sciencedirect.com/science/article/pii/S2589004223024252
Oct 2023
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TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.ccell.2023.09.001
  
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sciencedirect.com/science/article/pii/S1535610823003185
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Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer

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1. scibot 01 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.107937
  
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sciencedirect.com/science/article/pii/S258900422302014X
Apr 2023
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Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment

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1. scibot 07 Apr 2023
  
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  DOI: 10.1016/j.cell.2023.03.011
  
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cell.com/cell/fulltext/S0092-8674(23)00271-4
Jan 2023
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MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors

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1. scibot 19 Jan 2023
  
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  DOI: 10.1016/j.ccell.2022.12.007
  
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Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1

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1. scibot 07 Jan 2023
  
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  DOI: 10.1158/2159-8290.CD-21-0900
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9262841/
Oct 2022
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Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy

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1. scibot 20 Oct 2022
  
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  DOI: 10.1016/j.immuni.2022.09.014
  
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sciencedirect.com/science/article/pii/S1074761322005088
Sep 2022
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Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma

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1. scibot 02 Sep 2022
  
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  DOI: 10.1158/2159-8290.CD-21-1077
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8904298/
Aug 2022
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Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα

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1. scibot 25 Aug 2022
  
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  DOI: 10.1016/j.cmet.2022.08.002
  
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sciencedirect.com/science/article/pii/S155041312200345X
Jun 2022
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cd-21-0900-html.html

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1. scibot 30 Jun 2022
  
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  DOI: 10.1158/2159-8290.cd-21-0900
  
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2. scibot 25 Jun 2022
  
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  DOI: 10.1158/2159-8290.cd-21-0900
  
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  DOI: 10.1158/2159-8290.cd-21-0900
  
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52.53.155.43/d5bf83c5c1736aa8a79b5cf8b82689398b415edf/cd-21-0900 (2)-html.html
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Flow cytometry analysis of endothelial cells and subsets of exhausted CD8+ T cells in murine tumor models

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1. scibot 09 Jun 2022
  
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  DOI: 10.1016/j.xpro.2022.101444
  
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sciencedirect.com/science/article/pii/S2666166722003240
Feb 2022
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Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy

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1. scibot 04 Feb 2022
  
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  DOI: 10.1016/j.ccell.2022.01.002
  
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sciencedirect.com/science/article/pii/S1535610822000046
Nov 2021
mct.aacrjournals.org mct.aacrjournals.org

Simultaneously Combined Cancer Cell- and CTLA4-Targeted NIR-PIT Causes a Synergistic Treatment Effect in Syngeneic Mouse Models

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1. scibot 24 Nov 2021
  
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  DOI: 10.1158/1535-7163.MCT-21-0470
  
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mct.aacrjournals.org/content/20/11/2262
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Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells

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1. scibot 18 Nov 2021
  
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  DOI: 10.1016/j.isci.2021.103347
  
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Sep 2021
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A TLR7 antagonist restricts interferon-dependent and -independent immunopathology in a mouse model of severe influenza

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  RRID:AB_1107791
  
  DOI: 10.1084/jem.20201631
  
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Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma

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  RRID:AB_1107791
  
  DOI: 10.1016/j.xcrm.2021.100399
  
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Untitled document

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  DOI: 10.1016/j.celrep.2018.11.047
  
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T cells drive negative feedback mechanisms in cancer associated fibroblasts, promoting expression of co-inhibitory ligands, CD73 and IL-27 in non-small cell lung cancer

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  RRID:AB_1107791
  
  DOI: 10.1080/2162402X.2021.1940675
  
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Jun 2021
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Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity

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  DOI: 10.1016/j.cell.2021.05.021
  
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Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity

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1. scibot 07 May 2021
  
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  DOI: 10.1016/j.molcel.2020.10.015
  
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Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade

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  DOI: 10.1016/j.molcel.2021.03.037
  
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Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer

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  InVivoPlus mouse IgG2b isotype control
  
  DOI: 10.1016/j.immuni.2021.02.020
  
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Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization

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CNTF-STAT3-IL-6 Axis Mediates Neuroinflammatory Cascade across Schwann Cell-Neuron-Microglia

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An Agonistic Anti-CD137 Antibody Disrupts Lymphoid Follicle Structure and T-Cell-Dependent Antibody Responses

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  DOI: 10.1016/j.xcrm.2020.100035
  
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B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer

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  DOI: 10.1016/j.cell.2019.10.028
  
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Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer

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  DOI: 10.1016/j.celrep.2019.03.066
  
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Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection

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  DOI: 10.1016/j.cell.2019.07.032
  
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The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity

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  DOI: 10.1016/j.immuni.2019.04.001
  
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Untitled document

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  DOI: 10.1016/j.stem.2019.01.011
  
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Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation

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  DOI: 10.1016/j.ccell.2019.04.003
  
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IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy

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Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity

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