203 Matching Annotations
  1. Sep 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC13524019/
  3. Aug 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FOXA1 drives chemoresistance through activating Wnt pathway in small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13458387/
  5. Jul 2026
  6. www.biorxiv.org www.biorxiv.org
    Deciphering the Multiscale Morphology of Somatic Oncogenic Alterations in Hepatocellular Carcinoma
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    biorxiv.org/content/10.64898/2026.07.15.738764v1
  7. www.sciencedirect.com www.sciencedirect.com
    Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells
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    sciencedirect.com/science/article/pii/S1534580726002388
  8. link.springer.com link.springer.com
    Electroacupuncture-modulated DHCR24 facilitates spinal cord injury recovery by attenuating apoptosis and neuroinflammation via the Wnt signaling pathway
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    link.springer.com/article/10.1007/s11011-026-01919-4
  9. academic.oup.com academic.oup.com
    Dual Targeting of Orphan Nuclear Receptors NR4A1 and NR4A2 for Non-Hormonal Endometriosis Therapy
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    academic.oup.com/endo/article/166/11/bqaf144/8266318
  10. Jun 2026
  11. aacrjournals.org aacrjournals.org
    ZC3H13 Loss Drives Cancer Metastatic Progression by Disrupting m6A RNA Methylation
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    aacrjournals.org/cancerres/article/86/3/622/771927/ZC3H13-Loss-Drives-Cancer-Metastatic-Progression
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    PKCα-mediated nuclear translocation of cGAS stabilizes β-catenin and drives metastasis
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    sciencedirect.com/science/article/pii/S1097276526003473
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    Distinct ERK and PI3K dependencies mediate a heterogeneous response to RAS(ON) inhibition in KRAS-mutant colorectal cancer
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    sciencedirect.com/science/article/pii/S2211124726006376
  14. May 2026
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    Druggable β-catenin palmitoyl-switch coordinates immune evasion via immunogenic ferroptosis resistance and PD-L1-mediated immunosuppression
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    sciencedirect.com/science/article/pii/S2666379126002545
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    Wnt5b/FZD1/LRP6 signaling drives renal fibrosis by triggering cytoplasmic stabilization and nuclear translocation of β-catenin under hypoxia
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    sciencedirect.com/science/article/pii/S258900422601504X
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Wnt3-mediated fibrosis and carcinogenesis of lung squamous cell carcinoma in idiopathic pulmonary fibrosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13127482/
  18. Apr 2026
  19. aacrjournals.org aacrjournals.org
    Loss of Regulator of G protein signaling 11 promotes pro-tumorigenic features in pancreatic cancer
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    aacrjournals.org/mcr/article/24/1/34/771151/Loss-of-Regulator-of-G-Protein-Signaling-11
  20. www.sciencedirect.com www.sciencedirect.com
    Electromagnetic field-inducible in vivo gene switch for remote spatiotemporal control of gene expression
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    sciencedirect.com/science/article/pii/S0092867426003302
  21. Mar 2026
  22. www.sciencedirect.com www.sciencedirect.com
    Maltol induces diabetic fragility fractures by disrupting the balance of bone remodeling
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    sciencedirect.com/science/article/pii/S1550413126000951
  23. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Localization of Puncta Adherentia Junctions at GABAergic Synapses on Parvalbumin-Positive GABAergic Inhibitory Neurons in the Mouse Hippocampus
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    onlinelibrary.wiley.com/doi/10.1002/cne.70152
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ROME, an Ancient Gene with a Novel Function in Vertebrates, Is a Key Modulator of Embryonal Development and Cancer Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012068/
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    Decoding the spatiotemporal development of the blood-brain barrier in human cortex
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    sciencedirect.com/science/article/pii/S1934590926000809
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Panx1 deficiency exacerbates GAN diet-induced obesity by destabilizing β-catenin via GSK3β
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    pmc.ncbi.nlm.nih.gov/articles/PMC12999355/
  27. www.biorxiv.org www.biorxiv.org
    A Niclosamide Prodrug SSL-0024 with Enhanced Bioavailability Suppresses Hepatocellular Carcinoma via Multi-Pathway Signaling Inhibition
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    biorxiv.org/content/10.64898/2026.03.06.710248v1
  28. Feb 2026
  29. www.sciencedirect.com www.sciencedirect.com
    SIRT1 mediates brain metabolic and developmental consequences of methionine synthase deficiency in inborn errors of cobalamin metabolism
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    sciencedirect.com/science/article/pii/S2666379126000601
  30. 54.241.53.176 54.241.53.176
    s12943-026-02568-y_reference-html.html
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  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Microbial Bile Acid Metabolite 3-oxo-LCA Inhibits Colorectal Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12871761/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting CAFs-Mediated Stromal Signaling in a Patient-Derived Organotypic Colorectal Tumor Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12316546/
  33. 54.241.53.176 54.241.53.176
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  34. Jan 2026
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Differential contribution of TFE3 isoforms to cell motility and invasion
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    pmc.ncbi.nlm.nih.gov/articles/PMC12852735/
  36. 54.241.53.176 54.241.53.176
    IRE1 signaling in osteoprogenitors augments β-catenin activity and physiologic bone accrual
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    54.241.53.176/8609f087e24f454e84a0b566240b0a325314ae9e/zjag001-html.html
  37. Dec 2025
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NEXN targeting MYOCD by facilitating EMT-related β-catenin nuclear translocation modulates the metastasis of hepatocellular carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12702233/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SM08502-Mediated β-Catenin Repression Synergizes with Olaparib to Inhibit Tumor Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12676110/
  40. Nov 2025
  41. 54.241.53.176 54.241.53.176
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    Non-orthosteric inhibition of enolase 1 impedes growth of triple-negative breast cancer
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  43. Oct 2025
  44. 54.241.53.176 54.241.53.176
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    Tuning insulin receptor signaling using de novo-designed agonists
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    sciencedirect.com/science/article/pii/S1097276525007804
  46. Sep 2025
  47. www.sciencedirect.com www.sciencedirect.com
    Cetuximab increases LGR5 expression and augments LGR5-targeting antibody-drug conjugate efficacy in patient-derived colorectal cancer models
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    sciencedirect.com/science/article/pii/S2666379125004367
  48. Jul 2025
  49. www.sciencedirect.com www.sciencedirect.com
    β-catenin functions as a molecular adapter for disordered cBAF interactions
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    sciencedirect.com/science/article/pii/S1097276525005763
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The XPO1 inhibitor Eltanexor modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260813/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Artificial intelligence-driven discovery of YH395A: A novel TGFβR1 inhibitor with potent anti-tumor activity against triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12235933/
  52. 52.53.155.43 52.53.155.43
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  53. www.biorxiv.org www.biorxiv.org
    Cetuximab increases LGR5 expression and augments LGR5-targeting antibody-drug conjugate efficacy in patient-derived colorectal cancer models
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    biorxiv.org/content/10.1101/2025.06.18.660406v1
  54. Jun 2025
  55. www.cell.com www.cell.com
    BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival
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    cell.com/molecular-cell/fulltext/S1097-2765(25)00499-X
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    PD-L1 Expression is Mediated by microRNA Processing, Wnt/β-Catenin Signaling, and Chemotherapy in Wilms Tumor
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    onlinelibrary.wiley.com/doi/10.1002/pbc.31852
  57. 52.53.155.43 52.53.155.43
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    Merlin controls limb development and thumb formation by regulating primary cilium-hedgehog signaling
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    sciencedirect.com/science/article/pii/S2211124725006205
  59. May 2025
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hippo signaling is essential for the maintenance of zona glomerulosa cell fate in the murine adrenal cortex
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    pmc.ncbi.nlm.nih.gov/articles/PMC12041920/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046322/
  62. www.sciencedirect.com www.sciencedirect.com
    Circular RNA circATM binds PARP1 to suppress Wnt/β-catenin signaling and induce cell cycle arrest in gastric cancer cells
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    sciencedirect.com/science/article/pii/S2090123225002772
  63. www.sciencedirect.com www.sciencedirect.com
    Glycosylation-driven programs coordinate immunoregulatory and pro-angiogenic functions of myeloid-derived suppressor cells
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    sciencedirect.com/science/article/pii/S1074761325001906
  64. Apr 2025
  65. 52.53.155.43 52.53.155.43
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  66. link.springer.com link.springer.com
    Ursodeoxycholic acid prompts glycolytic dominance, reductive stress and epithelial-to-mesenchymal transition in ovarian cancer cells through NRF2 activation
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    link.springer.com/article/10.1038/s41420-025-02398-9
  67. link.springer.com link.springer.com
    Human neuron chimeric mice reveal impairment of DVL-1-mediated neuronal migration by sevoflurane and potential treatment by rTMS
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    link.springer.com/article/10.1038/s12276-025-01425-0
  68. Mar 2025
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    mTOR regulates Wnt signaling to promote tension-mediated lens vesicle closure
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    pmc.ncbi.nlm.nih.gov/articles/PMC11888330/
  70. www.sciencedirect.com www.sciencedirect.com
    PAI-1-driven SFRP2high cancer-associated fibroblasts hijack the abscopal effect of radioimmunotherapy
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    sciencedirect.com/science/article/pii/S1535610825000765
  71. Feb 2025
  72. 52.53.155.43 52.53.155.43
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  73. aacrjournals.org aacrjournals.org
    HnRNPAB promotes pancreatic ductal adenocarcinoma extravasation and liver metastasis by stablizing MYC mRNA
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    aacrjournals.org/mcr/article/22/11/1022/749159/hnRNPAB-Promotes-Pancreatic-Ductal-Adenocarcinoma
  74. aacrjournals.org aacrjournals.org
    CCN6 suppresses metaplastic breast carcinoma by antagonizing WNT/β-catenin signaling to inhibit EZH2-driven EMT
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    aacrjournals.org/cancerres/article/84/19/3235/748708/CCN6-Suppresses-Metaplastic-Breast-Carcinoma-by
  75. 52.53.155.43 52.53.155.43
    Novel Pannexin 1 isoform is increased in cancer
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    52.53.155.43/248e2b0e257da849dadde63c071f77bcede2b26b/2024.09.09.612143v3.full-html.html
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225002160-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC11904601/
  77. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinase USP9X controls Wnt signaling for CNS vascular formation and barrier maintenance
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    sciencedirect.com/science/article/pii/S1534580725000292
  78. Jan 2025
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Missense Mutant p53 Transactivates Wnt/β-Catenin Signaling in Neighboring p53-Destabilized Cells through the COX-2/PGE2 Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695814/
  80. www.sciencedirect.com www.sciencedirect.com
    The de novo synthesis of GABA and its gene regulatory function control hepatocellular carcinoma metastasis
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    Gut bacterial L-lysine alters metabolism and histone methylation to drive dendritic cell tolerance
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  82. Dec 2024
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PD-L1 expression is mediated by microRNA processing, Wnt/β-catenin signaling, and chemotherapy in Wilms tumor
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    pmc.ncbi.nlm.nih.gov/articles/PMC11642745/
  84. Oct 2024
  85. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Jawbone periosteum-derived cells with high osteogenic potential controlled by R-spondin 3
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202400988RR
  86. Sep 2024
  87. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Function of a complex of p-Y42 RhoA GTPase and pyruvate kinase M2 in EGF signaling pathway in glioma cells
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16210
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11424096/
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    Marmoset and human trophoblast stem cells differ in signaling requirements and recapitulate divergent modes of trophoblast invasion
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    Lipolysis engages CD36 to promote ZBP1-mediated necroptosis-impairing lung regeneration in COPD
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  91. Aug 2024
  92. www.sciencedirect.com www.sciencedirect.com
    A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer
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    A primate-specific endogenous retroviral envelope protein sequesters SFRP2 to regulate human cardiomyocyte development
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  94. dmsjournal.biomedcentral.com dmsjournal.biomedcentral.com
    Exercise improves bone formation by upregulating the Wnt3a/β-catenin signalling pathway in type 2 diabetic mice
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    dmsjournal.biomedcentral.com/articles/10.1186/s13098-021-00732-6
  95. cancerci.biomedcentral.com cancerci.biomedcentral.com
    Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming
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    cancerci.biomedcentral.com/articles/10.1186/s12935-021-02303-1
  96. Jul 2024
  97. www.sciencedirect.com www.sciencedirect.com
    Both enantiomers of β-aminoisobutyric acid BAIBA regulate Fgf23 via MRGPRD receptor by activating distinct signaling pathways in osteocytes
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    Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration
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  99. May 2024
  100. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Astrocyte-derived CHI3L1 signaling impairs neurogenesis and cognition in the demyelinated hippocampus
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    sciencedirect.com/science/article/pii/S2211124724005540
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of tumor-associated AXIN1 missense mutations identifies variants that activate β-catenin signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11063763/
  103. Apr 2024
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of NEK2 Promotes Chemosensitivity and Reduces KSHV-positive Primary Effusion Lymphoma Burden
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    ncbi.nlm.nih.gov/pmc/articles/PMC11003453/
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Islet resident macrophage-derived miR-155 promotes β-cell decompensation via targeting PDX1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10993184/
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ISG12a promotes immunotherapy of HBV-associated hepatocellular carcinoma through blocking TRIM21/AKT/β-Catenin/PD-L1 axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11000115/
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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  244. Jan 2020
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