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  1. Last 7 days
  2. www.nature.com www.nature.com
    USP39 regulates pyruvate handling in non-small cell lung cancer
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  3. Dec 2024
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    Mapping functional elements of the DNA damage response through base editor screens
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    Paclitaxel triggers molecular and cellular changes in the choroid plexus
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    Two-ended recombination at a Flp-nickase-broken replication fork
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  7. Nov 2024
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    Opposing roles for AMPK in regulating distinct mitophagy pathways
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  9. Sep 2024
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    Facilitation of dopamine‐dependent long‐term potentiation in the medial prefrontal cortex of male rats follows the behavioral effects of stress
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  11. Jul 2024
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    Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation
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    Focal adhesion-mediated directional cell migration guided by gradient-stretched substrate
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    cell.com/iscience/fulltext/S2589-0042(24)01671-7
  14. May 2024
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    Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism
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  16. Apr 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Type I interferon regulation by USP18 is a key vulnerability in cancer
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    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
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    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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    Temporal dynamics and stoichiometry in human Notch signaling from Notch synaptic complex formation to nuclear entry of the Notch intracellular domain
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    sciencedirect.com/science/article/pii/S1534580724001898
  21. Mar 2024
  22. www.sciencedirect.com www.sciencedirect.com
    A unique chaperoning mechanism in class A JDPs recognizes and stabilizes mutant p53
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    sciencedirect.com/science/article/pii/S1097276524001370
  23. Feb 2024
  24. www.sciencedirect.com www.sciencedirect.com
    Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons
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    sciencedirect.com/science/article/pii/S2589004224003870
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    Increased matrix stiffness enhances pro-tumorigenic traits in a physiologically relevant breast tissue- monocyte 3D model
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      DOI: 10.1016/j.actbio.2024.02.021

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    sciencedirect.com/science/article/pii/S1742706124000898
  26. Jan 2024
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    ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1
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    sciencedirect.com/science/article/pii/S1534580723006986
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    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
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    sciencedirect.com/science/article/pii/S1534580723003945
  29. Dec 2023
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    A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas
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  31. Nov 2023
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    Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition
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    Global identification of SWI/SNF targets reveals compensation by EP400
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    Efficient exon skipping by base-editor-mediated abrogation of exonic splicing enhancers
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  35. Oct 2023
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    KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation
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    End binding-3 inhibitor activates regenerative program in age-related macular degeneration
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    sciencedirect.com/science/article/pii/S266637912300397X
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    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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    sciencedirect.com/science/article/pii/S1097276523007505
  39. 52.53.155.43 52.53.155.43
    Metformin Improves the Prerequisites for FGF21 Signaling in Patients with Type 2 Diabetes
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      DOI: 10.1210/clinem/dgad583

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    52.53.155.43/cc45dcfbebfa73b37f4edd139d2ebee0e2e7d2ed/dgad583-html.html
  40. Sep 2023
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    BPS Publications
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      DOI: 10.1111/bph.16196

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16196
  42. Jun 2023
  43. www.sciencedirect.com www.sciencedirect.com
    Coordinated linear and rotational movements of endothelial cells compartmentalized by VE-cadherin drive angiogenic sprouting
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      DOI: 10.1016/j.isci.2023.107051

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    sciencedirect.com/science/article/pii/S2589004223011288
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    FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
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      DOI: 10.1016/j.celrep.2023.112668

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    sciencedirect.com/science/article/pii/S2211124723006794
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Annexin A6 mediates calcium-dependent exosome secretion during plasma membrane repair
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      DOI: 10.7554/eLife.86556

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    ncbi.nlm.nih.gov/pmc/articles/PMC10241516/
  46. May 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Mechanical pressure-induced dedifferentiation of myofibroblasts inhibits scarring via SMYD3/ITGBL1 signaling
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    sciencedirect.com/science/article/pii/S1534580723001909
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    16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice
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    sciencedirect.com/science/article/pii/S2211124723004965
  49. Apr 2023
  50. www.sciencedirect.com www.sciencedirect.com
    Nuclear translocation of cGAS orchestrates VEGF-A-mediated angiogenesis
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      DOI: 10.1016/j.celrep.2023.112328

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    sciencedirect.com/science/article/pii/S221112472300339X
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    Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
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      DOI: 10.1016/j.cell.2023.02.035

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    sciencedirect.com/science/article/pii/S0092867423002131
  52. Feb 2023
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity
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      DOI: 10.1158/2159-8290.CD-22-0528

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    ncbi.nlm.nih.gov/pmc/articles/PMC9901536/
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    Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria
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      DOI: 10.1016/j.cell.2022.12.038

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    sciencedirect.com/science/article/pii/S0092867422015811
  55. Dec 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Huntingtin exon 1 deletion does not alter the subcellular distribution of huntingtin and gene transcription in mice
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      DOI: 10.3389/fncel.2022.1021592

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  57. Nov 2022
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    Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci
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  59. Oct 2022
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    Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes
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  61. Sep 2022
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    De novo sphingolipid biosynthesis necessitates detoxification in cancer cells
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    Target protein localization and its impact on PROTAC-mediated degradation
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  64. Aug 2022
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    Identification of Src as a Therapeutic Target in Oesophageal Adenocarcinoma through Functional Genomic and High-Throughput Drug Screening Approaches
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    Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity
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  67. Jul 2022
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    FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma
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  69. Jun 2022
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    A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency
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    Elevated levels of follicular fatty acids induce ovarian inflammation via ERK1/2 and inflammasome activation in PCOS
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  72. May 2022
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    A novel methodological approach to simultaneously extract high-quality total RNA and proteins from cortical and trabecular bone
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  74. Apr 2022
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    Canonical Wnt Signaling Induces Focal Adhesion and Integrin Beta-1 Endocytosis
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  76. Mar 2022
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    A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
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  78. Feb 2022
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    A M1 muscarinic acetylcholine receptor positive allosteric modulator improves pathology and cognitive deficits in female APPswe/PSEN1ΔE9 mice
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  80. Dec 2021
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    Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis
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  82. Nov 2021
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    Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine
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    Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer
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  85. Oct 2021
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    Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells
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  87. Sep 2021
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    Prolyl oligopeptidase inhibition reduces alpha-synuclein aggregation in a cellular model of multiple system atrophy
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    Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity
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  90. Aug 2021
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mouse screen reveals multiple new genes underlying mouse and human hearing loss
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  94. Jul 2021
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    Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis
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  96. May 2021
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    SeqStain is an efficient method for multiplexed, spatialomic profiling of human and murine tissues
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    Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
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  99. Apr 2021
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    Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer
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    Low expression of the PPARγ-regulated gene thioredoxin-interacting protein accompanies human melanoma progression and promotes experimental lung metastases
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      DOI: 10.1038/s41598-021-86329-5

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  102. Mar 2021
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    Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation
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  104. Dec 2020
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    Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
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  106. Nov 2020
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    PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage
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  108. Sep 2020
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    Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue
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    The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction
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    Goldfish adipocytes are pancreatic beta cell‐like, glucose‐responsive insulin‐producing cells
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  112. Jan 2020
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    Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions
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    Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles
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    Species specific differences in use of ANP32 proteins by influenza A virus
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    PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux
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    Differentiation of adipose-derived stem cells to functional CD105<Superscript>neg</Superscript> CD73<Superscript>low</Superscript> melanocyte precursors guided by defined culture condition
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      RRID:AB_11144129

      DOI: 10.1016/j.cmet.2019.01.014

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  120. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 12 Jan 2020
      RRID:AB_11144129

      DOI: 10.1016/j.ccell.2019.03.001

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  121. Nov 2018
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    sciencedirect.com/science/article/pii/S2211124718314773
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand
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      Curator: @evieth

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  124. Nov 2017
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    Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms
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      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0092867417306943