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PrPC-facilitated cell signaling activates phospholipase Cɣ1 and triggers an Arc/Arg3.1 response in mouse and iPSC-derived human neurons

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sciencedirect.com/science/article/pii/S2213671126001359
Apr 2026
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2026.04.20.719548.full-html.html

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54.241.53.176/c1c00486dbe489784861e140175fcdc5fdf9d6eb/2026.04.20.719548.full-html.html
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cardiomyocyte-specific LARP6 overexpression prevents angiotensin II-induced myocardial dysfunction and interstitial fibrosis

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  DOI: 10.1152/ajpheart.00196.2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12482548/
Sep 2025
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IGF2BP3 redirects glycolytic flux to promote one-carbon metabolism and RNA methylation

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sciencedirect.com/science/article/pii/S2211124725011015
Aug 2025
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YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition

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sciencedirect.com/science/article/pii/S2211124725009593
52.53.155.43 52.53.155.43

russell-et-al-2025-cardiomyocyte-specific-larp6-overexpression-prevents-angiotensin-ii-induced-myocardial-dysfunction-html.html

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52.53.155.43/cdc89213e8da95a53f691c27b85c44a7e3f558a7/russell-et-al-2025-cardiomyocyte-specific-larp6-overexpression-prevents-angiotensin-ii-induced-myocardial-dysfunction-html.html
Jul 2025
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Metabolomic Profiling Reveals Key Metabolic Alterations in MCF7 Tamoxifen-Resistant Cells Following EPAS1 Inhibition

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  DOI: 10.1021/acs.jproteome.5c00170
  
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pubs.acs.org/doi/10.1021/acs.jproteome.5c00170
Jun 2025
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The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway

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sciencedirect.com/science/article/pii/S1074761325002444
May 2025
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Specific degrader for fusion oncokinase kills tumors and is augmented by bimodal degrader-siRNA

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biorxiv.org/content/10.1101/2025.04.24.650501v1
Mar 2025
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Upregulation of Cathepsin S Expression Contributes to Neuronal Damage Following Kainic Acid–Induced Status Epilepticus

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  DOI: 10.1111/jnc.70037
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.70037
Jan 2025
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C9ORF72 poly-PR induces TDP-43 nuclear condensation via NEAT1 and is modulated by HSP70 activity

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sciencedirect.com/science/article/pii/S2211124724015249
Dec 2024
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Modelling quiescence exit of neural stem cells reveals a FOXG1-FOXO6 axis

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pmc.ncbi.nlm.nih.gov/articles/PMC11625887/
Nov 2024
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miRNA-mediated control of gephyrin synthesis drives sustained inhibitory synaptic plasticity

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pmc.ncbi.nlm.nih.gov/articles/PMC11549329/
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E2F3a Activates Gadd45b Gene Expression Through PPARα-Mediated Transcriptional Regulation in Hepatic Cells

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sciencedirect.com/science/article/pii/S1016847824001730
Sep 2024
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Clearing the JUNQ: the molecular machinery for sequestration, localization, and degradation of the JUNQ compartment

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  DOI: 10.3389/fmolb.2024.1427542
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11372896/
Jul 2024
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Genome-wide quantification of RNA flow across subcellular compartments reveals determinants of the mammalian transcript life cycle

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cell.com/molecular-cell/fulltext/S1097-2765(24)00511-2
May 2024
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Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model

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biorxiv.org/content/10.1101/2024.01.24.577107v1
Feb 2024
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A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells

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ncbi.nlm.nih.gov/pmc/articles/PMC10805602/
Jan 2024
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SARS-CoV-2 Antigen-Carrying Extracellular Vesicles Activate T Cell Responses in a Human Immunogenicity Model

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ncbi.nlm.nih.gov/pmc/articles/PMC10788222/
Dec 2023
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FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination

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sciencedirect.com/science/article/pii/S2211124723015358
Nov 2023
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Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition

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sciencedirect.com/science/article/pii/S1097276523008547
Oct 2023
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Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism

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sciencedirect.com/science/article/pii/S2211124723012536
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Distinct mechanisms drive sequential internalization and degradation of GABAARs during global ischemia and reperfusion injury

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cell.com/iscience/abstract/S2589-0042(23)02138-7
Sep 2023
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Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma

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  DOI: 10.1038/s41375-023-02013-9
  
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nature.com/articles/s41375-023-02013-9
Apr 2023
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Fanconi anemia-associated chromosomal radial formation is dependent on POLθ-mediated alternative end joining

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sciencedirect.com/science/article/pii/S2211124723004394
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Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals

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sciencedirect.com/science/article/pii/S1550413123001304
Mar 2023
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The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation

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sciencedirect.com/science/article/pii/S221112472300222X
Feb 2023
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Cannabidiol modulates excitatory-inhibitory ratio to counter hippocampal hyperactivity

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  DOI: 10.1016/j.neuron.2023.01.018
  
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sciencedirect.com/science/article/pii/S0896627323000661
Jun 2022
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability

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pmc.ncbi.nlm.nih.gov/articles/PMC9356996/
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Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

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sciencedirect.com/science/article/pii/S0960982222007783
Apr 2022
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RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development

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  DOI: 10.1016/j.devcel.2022.03.017
  
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sciencedirect.com/science/article/pii/S1534580722002118
Jan 2022
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Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

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  DOI: 10.1016/j.cell.2021.12.041
  
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sciencedirect.com/science/article/pii/S0092867421015634
Dec 2021
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Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity

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  DOI: 10.1016/j.celrep.2021.110142
  
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sciencedirect.com/science/article/pii/S2211124721016387
Nov 2021
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Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs

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  DOI: 10.1016/j.molcel.2021.10.018
  
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Conditional Deletion of the L-Type Calcium Channel Cav1.2 in Oligodendrocyte Progenitor Cells Affects Postnatal Myelination in Mice

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NADPH Oxidase Mediates Membrane Androgen Receptor–Induced Neurodegeneration

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1. scibot 31 Jul 2021
  
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Differential Effects of Toll-Like Receptor Activation and Differential Mediation by MAP Kinases of Immune Responses in Microglial Cells

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  DOI: 10.1007/s10571-021-01127-x
  
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Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants

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GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes

1
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  DOI: 10.1038/s41598-020-69913-z
  
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A Conserved Kinase-Based Body-Temperature Sensor Globally Controls Alternative Splicing and Gene Expression

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  DOI: 10.1016/j.molcel.2020.01.028
  
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Local miRNA-Dependent Translational Control of GABAAR Synthesis during Inhibitory Long-Term Potentiation

1
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  DOI: 10.1016/j.celrep.2020.107785
  
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Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation

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  DOI: 10.1016/j.molcel.2020.01.003
  
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ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase

1
1. scibot 04 Sep 2020
  
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  DOI: 10.1016/j.cmet.2020.03.008
  
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Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/β-catenin Signaling

1
1. scibot 04 Sep 2020
  
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  anti-GAPDH
  
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High-Throughput Assessment of Kinome-wide Activation States

1
1. scibot 13 Jan 2020
  
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  RRID:AB_11174761
  
  DOI: 10.1016/j.cels.2019.08.005
  
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Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila

1
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High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells

1
1. scibot 13 Jan 2020
  
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NADPH Oxidase Mediates Membrane Androgen Receptor–Induced Neurodegeneration

1
1. scibot 13 Jan 2020
  
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Nov 2018
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The Divalent Metal Transporter 1 (DMT1) Is Required for Iron Uptake and Normal Development of Oligodendrocyte Progenitor Cells

1
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Untitled document

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Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2

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Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin

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Untitled document

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Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets

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europepmc.org europepmc.org

The Histamine H1 Receptor Participates in the Increased Dorsal Telencephalic Neurogenesis in Embryos from Diabetic Rats.

1
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europepmc.org/articles/PMC5735119/
Nov 2017
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Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells

1
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Body Temperature Cycles Control Rhythmic Alternative Splicing in Mammals

1
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Conditional Deletion of the L-Type Calcium Channel Cav1.2 in Oligodendrocyte Progenitor Cells Affects Postnatal Myelination in Mice

1
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Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration

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