117 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways
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    1. scibot 02 Dec 2024
      AB_11178668

      DOI: 10.1016/j.celrep.2024.114984

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    sciencedirect.com/science/article/pii/S2211124724013354
  3. Nov 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Opposing roles for AMPK in regulating distinct mitophagy pathways
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    1. scibot 20 Nov 2024
      RRID:AB_11178668

      DOI: 10.1016/j.molcel.2024.10.025

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    sciencedirect.com/science/article/pii/S1097276524008657
  5. Oct 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux
    1
    1. scibot 05 Oct 2024
      RRID:AB_11178668

      DOI: 10.1016/j.chembiol.2023.06.016

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    ncbi.nlm.nih.gov/pmc/articles/PMC11426993/
  7. Sep 2024
  8. www.sciencedirect.com www.sciencedirect.com
    The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization
    1
    1. scibot 13 Sep 2024
      RRID:AB_11178668

      DOI: 10.1016/j.celrep.2024.114689

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    sciencedirect.com/science/article/pii/S2211124724010404
  9. aacrjournals.org aacrjournals.org
    Activating mTOR mutations are detrimental in nutrient-poor conditions
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    1. scibot 12 Sep 2024
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      DOI: 10.1158/0008-5472.CAN-22-0121

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    aacrjournals.org/cancerres/article/82/18/3263/709030/Activating-mTOR-Mutations-Are-Detrimental-in
  10. www.sciencedirect.com www.sciencedirect.com
    Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis
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    1. scibot 11 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114728

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    sciencedirect.com/science/article/pii/S2211124724010799
  11. Aug 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Non-canonical metabolic and molecular effects of calorie restriction are revealed by varying temporal conditions
    1
    1. scibot 22 Aug 2024
      RRID:AB_11178668

      DOI: 10.1016/j.celrep.2024.114663

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    sciencedirect.com/science/article/pii/S2211124724010143
  13. academic.oup.com academic.oup.com
    Adiponectin inhibits the progression of obesity-associated papillary thyroid carcinoma through autophagy
    1
    1. scibot 13 Aug 2024
      RRID:AB_11178668

      DOI: 10.1210/endocr/bqae030

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    academic.oup.com/endo/article-abstract/165/5/bqae030/7630457
  14. www.tandfonline.com www.tandfonline.com
    M. tuberculosis PknG manipulates host autophagy flux to promote pathogen intracellular survival
    1
    1. scibot 02 Aug 2024
      8054

      DOI: 10.1080/15548627.2021.1938912

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    tandfonline.com/doi/full/10.1080/15548627.2021.1938912
  15. www.cell.com www.cell.com
    RIPK1 Promotes Energy Sensing by the mTORC1 Pathway
    1
    1. scibot 02 Aug 2024
      ULK1

      DOI: 10.1016/j.molcel.2020.11.008

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30786-3
  16. Jul 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Cell-specific Nav1.6 knockdown reduced astrocyte-derived Aβ by reverse Na+-Ca2+ transporter-mediated autophagy in alzheimer-like mice
    1
    1. scibot 30 Jul 2024
      AB_11178668

      DOI: 10.1016/j.jare.2024.07.024

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    sciencedirect.com/science/article/pii/S2090123224003096
  18. www.sciencedirect.com www.sciencedirect.com
    Pro-survival signaling regulates lipophagy essential for multiple myeloma resistance to stress-induced death
    1
    1. scibot 18 Jul 2024
      AB_11178668

      DOI: 10.1016/j.celrep.2024.114445

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    sciencedirect.com/science/article/pii/S2211124724007745
  19. www.sciencedirect.com www.sciencedirect.com
    Increased regional activity of a pro-autophagy pathway in schizophrenia as a contributor to sex differences in the disease pathology
    1
    1. scibot 17 Jul 2024
      AB_11178668

      DOI: 10.1016/j.xcrm.2024.101652

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    sciencedirect.com/science/article/pii/S2666379124003665
  20. elifesciences.org elifesciences.org
    Novel autophagy inducers by accelerating lysosomal clustering against Parkinson’s disease
    1
    1. scibot 04 Jul 2024
      RRID:AB_11178668

      DOI: 10.7554/eLife.98649

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    elifesciences.org/articles/98649
  21. Jun 2024
  22. link.springer.com link.springer.com
    ATG16L1 induces the formation of phagophore-like membrane cups
    1
    1. scibot 06 Jun 2024
      RRID:AB_11178668

      DOI: 10.1038/s41594-024-01300-y

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    link.springer.com/article/10.1038/s41594-024-01300-y
  23. May 2024
  24. www.sciencedirect.com www.sciencedirect.com
    TBK1 is ubiquitinated by TRIM5α to assemble mitophagy machinery
    1
    1. scibot 30 May 2024
      RRID:AB_11178668

      DOI: 10.1016/j.celrep.2024.114294

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    sciencedirect.com/science/article/pii/S2211124724006223
  25. www.sciencedirect.com www.sciencedirect.com
    Leucyl-tRNA synthetase contributes to muscle weakness through mTORC1 activation and autophagy suppression in a mouse model of Duchenne Muscular Dystrophy
    1
    1. scibot 17 May 2024
      RRID:AB_11178668

      DOI: 10.1016/j.ajpath.2024.04.006

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    sciencedirect.com/science/article/pii/S0002944024001743
  26. Apr 2024
  27. www.sciencedirect.com www.sciencedirect.com
    An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade
    1
    1. scibot 02 Apr 2024
      Cell Signaling Technology8054S

      DOI: 10.1016/j.celrep.2024.114020

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    sciencedirect.com/science/article/pii/S2211124724003486
  28. Feb 2024
  29. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 16 Feb 2024
      RRID:AB_11178668

      DOI: 10.1111/bph.16283

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16283
  30. 52.53.155.43 52.53.155.43
    mTOR regulates mineralocorticoid receptor transcriptional activity by ULK1- dependent and independent mechanisms
    1
    1. scibot 15 Feb 2024
      AB_11178668

      DOI: 10.1210/endocr/bqae015

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  31. www.sciencedirect.com www.sciencedirect.com
    Proline restores mitochondrial function and reverses aging hallmarks in senescent cells
    1
    1. scibot 14 Feb 2024
      RRID:AB_11178668

      DOI: 10.1016/j.celrep.2024.113738

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    sciencedirect.com/science/article/pii/S2211124724000664
  32. Jan 2024
  33. www.sciencedirect.com www.sciencedirect.com
    Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression
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    1. scibot 11 Jan 2024
      RRID:AB_11178668

      DOI: 10.1016/j.celrep.2023.113575

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    sciencedirect.com/science/article/pii/S2211124723015875
  34. Dec 2023
  35. www.sciencedirect.com www.sciencedirect.com
    MORG1 limits mTORC1 signaling by inhibiting Rag GTPases
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    1. scibot 16 Dec 2023
      RRID:AB_11178668

      DOI: 10.1016/j.molcel.2023.11.023

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    sciencedirect.com/science/article/pii/S1097276523009681
  36. www.sciencedirect.com www.sciencedirect.com
    Nutrient-regulated control of lysosome function by signaling lipid conversion
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    1. scibot 02 Dec 2023
      RRID:AB_11178668

      DOI: 10.1016/j.cell.2023.09.027

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    sciencedirect.com/science/article/pii/S0092867423010814
  37. Nov 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Macrophage AMPK β1 activation by PF-06409577 reduces the inflammatory response, cholesterol synthesis, and atherosclerosis in mice
    1
    1. scibot 29 Nov 2023
      RRID:AB_11178668

      DOI: 10.1016/j.isci.2023.108269

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    sciencedirect.com/science/article/pii/S2589004223023465
  39. www.sciencedirect.com www.sciencedirect.com
    An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant
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    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113484

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    sciencedirect.com/science/article/pii/S2211124723014961
  40. Oct 2023
  41. 52.53.155.43 52.53.155.43
    s41586-023-06657-6_reference-html.html
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    1. scibot 06 Oct 2023
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      DOI: 10.1038/s41586-023-06657-6

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  42. Sep 2023
  43. www.biorxiv.org www.biorxiv.org
    Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
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    1. scibot 30 Sep 2023
      RRID:AB_11178668

      DOI: 10.1101/2023.09.25.559255

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    biorxiv.org/content/10.1101/2023.09.25.559255v1
  44. Aug 2023
  45. 52.53.155.43 52.53.155.43
    PIIS2589004223017029-html.html
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    1. scibot 18 Aug 2023
      RRID:AB_11178668

      DOI: 10.1016/j.isci.2023.107625

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  46. Jul 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
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    1. scibot 15 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112807

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    sciencedirect.com/science/article/pii/S2211124723008185
  48. Jun 2023
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Restored autophagy is protective against PAK3-induced cardiac dysfunction
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    1. scibot 17 Jun 2023
      RRID:AB_11178668

      DOI: 10.1016/j.isci.2023.106970

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    ncbi.nlm.nih.gov/pmc/articles/PMC10265534/
  50. www.embopress.org www.embopress.org
    Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response
    1
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      DOI: 10.15252/embj.2022113349

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    embopress.org/doi/10.15252/embj.2022113349
  51. aacrjournals.org aacrjournals.org
    Dysregulation of mitochondrial translation caused by CBFB deficiency cooperates with mutant PIK3CA and is a vulnerability in breast cancer
    1
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      DOI: 10.1158/0008-5472.CAN-22-2525

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    aacrjournals.org/cancerres/article/83/8/1280/725099/Dysregulation-of-Mitochondrial-Translation-Caused
  52. aacrjournals.org aacrjournals.org
    Targeting CHAF1B enhances Interferon activity against Myeloproliferative Neoplasm cells
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    1. scibot 02 Jun 2023
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      DOI: 10.1158/2767-9764.CRC-23-0010

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    aacrjournals.org/cancerrescommun/article/3/5/943/727012/Targeting-CHAF1B-Enhances-IFN-Activity-against
  53. May 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity
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      DOI: 10.1016/j.ccell.2023.04.016

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    sciencedirect.com/science/article/pii/S1535610823001423
  55. www.sciencedirect.com www.sciencedirect.com
    Metamorphic proteins at the basis of human autophagy initiation and lipid transfer
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    1. scibot 20 May 2023
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      DOI: 10.1016/j.molcel.2023.04.026

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    sciencedirect.com/science/article/pii/S1097276523003210
  56. www.sciencedirect.com www.sciencedirect.com
    Unconventional initiation of PINK1/Parkin mitophagy by Optineurin
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    1. scibot 19 May 2023
      RRID:AB_11178668

      DOI: 10.1016/j.molcel.2023.04.021

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    sciencedirect.com/science/article/pii/S1097276523002927
  57. Apr 2023
  58. europepmc.org europepmc.org
    A Novel Method for Visualizing In-Vivo Rates of Protein Degradation Provides Insight into how TRIM28 Regulates Muscle Size
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    1. scibot 20 Apr 2023
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      DOI: 10.1016/j.isci.2023.106526

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    europepmc.org/article/pmc/pmc10105291
  59. www.sciencedirect.com www.sciencedirect.com
    CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth
    1
    1. scibot 06 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112316

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  60. Feb 2023
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  62. Dec 2022
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    Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis
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    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
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  67. Nov 2022
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  69. Oct 2022
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    Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D
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    Hyperactivation of mTOR and AKT in a cardiac hypertrophy animal model of Friedreich ataxia
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    T cells mediate kidney tubular injury via impaired PDHA1 and Autophagy in type 1 diabetes
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  78. Jun 2022
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    Deficiency of C1QL1 reduced murine ovarian follicle reserve through intraovarian and endocrine control
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  80. Apr 2022
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    Cholesterol suppresses GOLM1-dependent selective autophagy of RTKs in hepatocellular carcinoma
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    DGAT1 activity synchronises with mitophagy to protect cells from metabolic rewiring by iron  depletion
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  83. Mar 2022
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    DRAM-4 and DRAM-5 are compensatory regulators of autophagy and cell survival in nutrient-deprived conditions
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  85. Feb 2022
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  87. Jan 2022
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    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
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  90. Sep 2021
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    PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis
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  93. Aug 2021
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  98. Jul 2021
  99. stemcellsjournals.onlinelibrary.wiley.com stemcellsjournals.onlinelibrary.wiley.com
    Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates osteogenic differentiation by modulating AMPK/ULK1‐dependent autophagy
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    Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins
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      Rabbit monoclonal Anti-ULK1

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  105. Jun 2021
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    High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol
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  107. May 2021
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    Systematic Functional Analysis of SARS-CoV-2 Proteins Uncovers Viral Innate Immune Antagonists and Remaining Vulnerabilities
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    ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system
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    Inositol Polyphosphate Multikinase Inhibits Liquid-Liquid Phase Separation of TFEB to Negatively Regulate Autophagy Activity
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  115. Mar 2021
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    Lifelong Ulk1-Mediated Autophagy Deficiency in Muscle Induces Mitochondrial Dysfunction and Contractile Weakness
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  135. Jan 2020
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    ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12–ATG5-ATG16L1 complex assembly and autophagy
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    Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons
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    The ER-Localized Transmembrane Protein TMEM39A/SUSR2 Regulates Autophagy by Controlling the Trafficking of the PtdIns(4)P Phosphatase SAC1
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    Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy
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    Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models
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    Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma
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    Helicobacter pylori Infection Modulates Host Cell Metabolism through VacA-Dependent Inhibition of mTORC1
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    The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis
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    CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis
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  156. Nov 2017
  157. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tumor necrosis factor receptor‐associated factor 6 participates in early brain injury after subarachnoid hemorrhage in rats through inhibiting autophagy and promoting oxidative stress
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    The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation
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    Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy
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    DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy
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    Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator
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      RRID:AB_11178668
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    ncbi.nlm.nih.gov/pmc/articles/PMC4931344/