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36 Matching Annotations

May 2025
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YTHDF1 differentiates the contributing roles of mTORC1 in aging

1
1. scibot 29 May 2025
  
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  DOI: 10.1016/j.molcel.2025.05.003
  
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sciencedirect.com/science/article/pii/S1097276525004083
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Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV

1
1. scibot 17 May 2025
  
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  DOI: 10.1016/j.cmet.2025.04.015
  
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sciencedirect.com/science/article/pii/S1550413125002530
Apr 2025
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STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation in lysosomal storage disorders

1
1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.molcel.2025.03.008
  
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sciencedirect.com/science/article/pii/S1097276525002011
Mar 2025
www.cell.com www.cell.com

Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression

1
1. scibot 23 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.023
  
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cell.com/immunity/fulltext/S1074-7613(25)00090-1
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KCTD20 suppression mitigates excitotoxicity in tauopathy patient organoids

1
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  DOI: 10.1016/j.neuron.2025.02.001
  
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sciencedirect.com/science/article/pii/S089662732500114X
Feb 2025
www.jneurosci.org www.jneurosci.org

TFEB/3 govern repair Schwann cell generation and function following peripheral nerve injury

1
1. scibot 27 Feb 2025
  
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  DOI: 10.1523/JNEUROSCI.0198-24.2024
  
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jneurosci.org/content/44/35/e0198242024
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Evolutionary conserved regulation of TFEB stability by the E3 ubiquitin ligase WWP2 modulates response to stress in vivo

1
1. scibot 07 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.111838
  
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sciencedirect.com/science/article/pii/S2589004225000987
Dec 2024
www.cell.com www.cell.com

TFEB triggers a matrix degradation and invasion program in triple-negative breast cancer cells upon mTORC1 repression

1
1. scibot 29 Dec 2024
  
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  DOI: 10.1016/j.devcel.2024.12.005
  
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cell.com/developmental-cell/fulltext/S1534-5807(24)00727-5
Sep 2024
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A TBK1-independent primordial function of STING in lysosomal biogenesis

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.molcel.2024.08.026
  
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sciencedirect.com/science/article/pii/S1097276524007032
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury

1
1. scibot 24 Apr 2024
  
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  DOI: 10.7554/eLife.92243
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11034944/
Feb 2024
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hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility

1
1. scibot 24 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113769
  
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sciencedirect.com/science/article/pii/S2211124724000974
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice

1
1. scibot 24 Jan 2024
  
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  DOI: 10.3389/fcvm.2023.1323760
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10800928/
Dec 2023
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Nutrient-regulated control of lysosome function by signaling lipid conversion

1
1. scibot 02 Dec 2023
  
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  AB_11204751
  
  DOI: 10.1016/j.cell.2023.09.027
  
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sciencedirect.com/science/article/pii/S0092867423010814
Sep 2023
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Sphingosine Kinase 1 is Involved in Triglyceride Breakdown by Maintaining Lysosomal Integrity in Brown Adipocytes

1
1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.jlr.2023.100450
  
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sciencedirect.com/science/article/pii/S0022227523001232
Aug 2023
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Human microglia maturation is underpinned by specific gene regulatory networks

1
1. scibot 16 Aug 2023
  
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  RRID:AB_11204751
  
  DOI: 10.1016/j.immuni.2023.07.016
  
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sciencedirect.com/science/article/pii/S1074761323003291
52.53.155.43 52.53.155.43

PIIS2211124723009543-html.html

1
1. scibot 12 Aug 2023
  
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  RRID:AB_11204751
  
  DOI: 10.1016/j.celrep.2023.112943
  
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52.53.155.43/7a7cd2b37d518c0daab3f29f5b28b810c1030ef5/PIIS2211124723009543-html.html
Mar 2023
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Sustained alternate-day fasting potentiates doxorubicin cardiotoxicity

1
1. scibot 03 Mar 2023
  
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  RRID:AB_11204751
  
  DOI: 10.1016/j.cmet.2023.02.006
  
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sciencedirect.com/science/article/pii/S1550413123000426
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PIKFYVE inhibition mitigates disease in models of diverse forms of ALS

1
1. scibot 09 Feb 2023
  
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  RRID:AB_11204751
  
  DOI: 10.1016/j.cell.2023.01.005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10062012/
Aug 2021
europepmc.org europepmc.org

Untitled document

1
1. scibot 03 Aug 2021
  
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  DOI: 10.7554/eLife.40856
  
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europepmc.org/articles/PMC6292694/
Jul 2021
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Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

1
1. scibot 29 Jul 2021
  
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  RID:AB_11204751
  
  DOI: 10.1016/j.molcel.2019.08.005
  
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sciencedirect.com/science/article/pii/S1097276519306215
europepmc.org europepmc.org

Untitled document

1
1. scibot 27 Jul 2021
  
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  RRID:AB_11204751WB
  
  DOI: 10.7554/eLife.40856
  
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  RRID:AB_11204751 RRIDCUR:Unresolved RRIDCUR:Incorrect
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europepmc.org/abstract/MED/30520728
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Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs

1
1. scibot 14 Jul 2021
  
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  DOI: 10.1016/j.celrep.2021.109372
  
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sciencedirect.com/science/article/pii/S2211124721007701
Jun 2021
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Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome

1
1. scibot 30 Jun 2021
  
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  RRID:AB_11204751
  
  DOI: 10.1016/j.celrep.2021.109321
  
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sciencedirect.com/science/article/pii/S2211124721006975
Apr 2021
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Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons

1
1. scibot 28 Apr 2021
  
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  RRID:AB_11204751
  
  DOI: 10.1016/j.celrep.2021.109034
  
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sciencedirect.com/science/article/pii/S2211124721003508
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Dietary spermidine improves cognitive function

1
1. scibot 16 Apr 2021
  
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  RRID:AB_11204751
  
  DOI: 10.1016/j.celrep.2021.108985
  
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  RRIDCUR:Validated RRID:AB_11204751
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sciencedirect.com/science/article/pii/S2211124721002990
Jan 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS

1
1. scibot 06 Jan 2021
  
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  RRID:AB_11204751
  
  DOI: 10.7554/eLife.59419
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7758070/
Dec 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses

1
1. scibot 25 Dec 2020
  
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  DOI: 10.7554/eLife.57950
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7744099/
Oct 2020
www.jneurosci.org www.jneurosci.org

14,15-epoxyeicosatrienoic acid alleviates pathology in a mouse model of Alzheimer’s disease

1
1. scibot 22 Oct 2020
  
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  DOI: 10.1523/JNEUROSCI.1246-20.2020
  
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  RRIDCUR:Validated RRID:AB_11204751
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jneurosci.org/content/40/42/8188
Sep 2020
www.nature.com www.nature.com

Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models

1
1. scibot 03 Sep 2020
  
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  RRID:AB_11204751
  
  DOI: 10.1038/s41419-020-2322-6
  
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  RRID:AB_11204751 RRIDCUR:Validated
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nature.com/articles/s41419-020-2322-6
Jan 2020
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Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.neuron.2019.09.001
  
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sciencedirect.com/science/article/pii/S0896627319307743
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_11204751
  
  DOI: 10.1016/j.devcel.2018.10.003
  
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  Curator: @Jmenke
  
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  RRID:AB_11204751 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1534580718308244
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_11204751
  
  DOI: 10.1016/j.celrep.2018.11.077
  
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  RRID:AB_11204751 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718318680
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.7554/eLife.40856
  
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  RRID:AB_11204751 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6292694/
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Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models

1
1. scibot 12 Jan 2020
  
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  RRID:AB_11204751
  
  DOI: 10.1016/j.cmet.2018.10.005
  
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  RRID:AB_11204751 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413118306375
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Untitled document

1
1. scibot 12 Jan 2020
  
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  RRID:AB_11204751
  
  DOI: 10.1016/j.celrep.2019.02.102
  
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  Curator: @ethanbadger
  
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  RRID:AB_11204751 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719302888
Nov 2018
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Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration

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1. scibot 05 Nov 2018
  
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RRID:AB_11204751

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scibot

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sciencedirect.com/science/article/pii/S096098221731391X