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Sep 2026
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SERINC2-mediated phosphatidylserine remodeling activates protrusion-localized AXL signaling to promote brain metastasis

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sciencedirect.com/science/article/pii/S2211124726010405
Aug 2026
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JI017 Sensitizes EGFR-T790M NSCLC to Erlotinib by Extinguishing the STAT3–Survivin Axis

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pmc.ncbi.nlm.nih.gov/articles/PMC13438235/
Jul 2026
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Acquisition of resistance to RAS inhibition is associated with the upregulation of macropinocytosis through both PI3K-dependent and -independent signaling

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AXL phosphosite mapping links FAK1 and YAP1 signaling to erlotinib resistance in EGFR-mutant lung cancer

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Cryopreservable dopaminergic progenitors derived from human iPSCs with accelerated loss of pluripotency and early functional restoration in Parkinsonian rats

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pmc.ncbi.nlm.nih.gov/articles/PMC13316032/
May 2026
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A regulatory circuitry driving a noradrenergic to mesenchymal transition highlights YAP/TAZ as critical players in neuroblastoma plasticity

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Mar 2026
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Transient proliferation by reversible YAP and mitogen control of the cyclin D1/p27 ratio

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pmc.ncbi.nlm.nih.gov/articles/PMC12957376/
Feb 2026
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VAV2 drives EGFR-mediated Rac1 responses in prostate cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC12324970/
Jan 2026
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Enhancing Tyro3 signaling ameliorates IL-1β production through STAT1 in Alzheimer's disease models

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CDK4/6 inhibition overcomes venetoclax resistance mechanisms with enhanced combination activity in acute myeloid leukemia

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pmc.ncbi.nlm.nih.gov/articles/PMC12866115/
Dec 2025
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Modeling human embryo implantation in vitro

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A BRN2:MYC transcriptional axis regulates interconversion between therapy-resistant and tumorigenic phenotypes in melanoma

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Nov 2025
54.241.53.176 54.241.53.176

1-s2.0-S2589004225023776-main-html.html

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Sep 2025
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PKN2 is a dependency of the mesenchymal-like cancer cell state

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pmc.ncbi.nlm.nih.gov/articles/PMC11875962/
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Elevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells

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pmc.ncbi.nlm.nih.gov/articles/PMC12398951/
Jul 2025
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SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung Adenocarcinoma

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pmc.ncbi.nlm.nih.gov/articles/PMC11695159/
Jun 2025
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Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation

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  DOI: 10.1016/j.chembiol.2025.05.005
  
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sciencedirect.com/science/article/pii/S2451945625001667
Apr 2025
52.53.155.43 52.53.155.43

PDF-html.html

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52.53.155.43/009f5d6e39c430064ce0b832cf798a7e9caafb80/PDF-html.html
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Fatty acid uptake activates an AXL–CAV1–β-catenin axis to drive melanoma progression

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pmc.ncbi.nlm.nih.gov/articles/PMC11960706/
Feb 2025
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AXL promotes lymphangiogenesis by amplifying VEGF-C-mediated AKT pathway

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  DOI: 10.1007/s00018-024-05542-3
  
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link.springer.com/article/10.1007/s00018-024-05542-3
Sep 2024
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Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription

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Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma

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A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib

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Aug 2024
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Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread

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May 2024
52.53.155.43 52.53.155.43

Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation

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52.53.155.43/5631ba0ece03be5b6bc39fba9c8a58e52d07c519/2024.01.21.576568v1.full-html.html
Apr 2024
aacrjournals.org aacrjournals.org

AXL/WRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2+ breast cancer

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  DOI: 10.1158/0008-5472.CAN-23-1459
  
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aacrjournals.org/cancerres/article/84/5/675/734930/AXL-WRNIP1-Mediates-Replication-Stress-Response
Aug 2023
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L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab

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Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer

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Jun 2023
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LZTR1 mutation mediates oncogenesis through stabilization of EGFR and AXL

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  DOI: 10.1158/2159-8290.CD-22-0376
  
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Feb 2023
52.53.155.43 52.53.155.43

cd-22-0376-html.html

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CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance

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  DOI: 10.1016/j.ccell.2023.01.007
  
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Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

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  DOI: 10.1016/j.molcel.2023.01.015
  
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Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease

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  DOI: 10.1016/j.immuni.2023.01.008
  
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sciencedirect.com/science/article/pii/S1074761323000183
Jan 2023
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ER-001259851-000, a novel selective inhibitor of AXL, overcomes resistance to antimitotic drugs

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  DOI: 10.1158/1535-7163.MCT-21-0879
  
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aacrjournals.org/mct/article/22/1/12/711996/ER-851-a-Novel-Selective-Inhibitor-of-AXL
Aug 2022
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ABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brain

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  DOI: 10.1016/j.celrep.2022.111268
  
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Jul 2022
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Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity

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Mar 2022
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AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells

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Feb 2022
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A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells

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Jan 2022
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SKI-G-801, an AXL kinase inhibitor, blocks metastasis through inducing anti-tumor immune responses and potentiates anti-PD-1 therapy in mouse cancer models

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onlinelibrary.wiley.com/doi/10.1002/cti2.1364
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BRAFV600E induces reversible mitotic arrest in human melanocytes via microrna-mediated suppression of AURKB

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  DOI: 10.7554/eLife.70385
  
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Nov 2021
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FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma

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Aug 2021
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The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway

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Jul 2021
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The effect of Zika virus infection in the ferret

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  DOI: 10.1002/cne.24640
  
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Apr 2021
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Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma

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Oct 2020
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Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells

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Sep 2020
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Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis

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Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

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Jan 2020
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Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity

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A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis

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The effect of Zika virus infection in the ferret

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OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ

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  DOI: 10.1016/j.molcel.2018.10.030
  
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sciencedirect.com/science/article/pii/S1097276518308906
Nov 2018
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Untitled document

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ncbi.nlm.nih.gov/pmc/articles/PMC6075866/
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Systematic Functional Annotation of Somatic Mutations in Cancer

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Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress

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sciencedirect.com/science/article/pii/S1535610818301223
Nov 2017
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Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids

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