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49 Matching Annotations

Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

VAV2 drives EGFR-mediated Rac1 responses in prostate cancer

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  DOI: 10.1158/1541-7786.MCR-24-0957
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12324970/
Jan 2026
dx.doi.org dx.doi.org

Enhancing Tyro3 signaling ameliorates IL-1β production through STAT1 in Alzheimer's disease models

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1. scibot 13 Jan 2026
  
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  DOI: 10.1093/jleuko/qiaf157
  
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dx.doi.org/10.1093/jleuko/qiaf157
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CDK4/6 inhibition overcomes venetoclax resistance mechanisms with enhanced combination activity in acute myeloid leukemia

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  DOI: 10.1016/j.xcrm.2025.102526
  
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sciencedirect.com/science/article/pii/S2666379125005993
Dec 2025
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Modeling human embryo implantation in vitro

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  DOI: 10.1016/j.cell.2025.10.027
  
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sciencedirect.com/science/article/pii/S0092867425012322
www.sciencedirect.com:5037 www.sciencedirect.com:5037

A BRN2:MYC transcriptional axis regulates interconversion between therapy-resistant and tumorigenic phenotypes in melanoma

1
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  DOI: 10.1016/j.celrep.2025.116675
  
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sciencedirect.com:5037/science/article/pii/S2211124725014470
Nov 2025
54.241.53.176 54.241.53.176

1-s2.0-S2589004225023776-main-html.html

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1. scibot 22 Nov 2025
  
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54.241.53.176/45c1150ef63729076f54080b9c6f662af1149eab/1-s2.0-S2589004225023776-main-html.html
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PKN2 is a dependency of the mesenchymal-like cancer cell state

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  DOI: 10.1158/2159-8290.CD-24-0928
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11875962/
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Elevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells

1
1. scibot 07 Sep 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-3267
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12398951/
Jul 2025
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SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung Adenocarcinoma

1
1. scibot 04 Jul 2025
  
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  DOI: 10.1158/0008-5472.CAN-23-3256
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11695159/
Jun 2025
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Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation

1
1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.chembiol.2025.05.005
  
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sciencedirect.com/science/article/pii/S2451945625001667
Apr 2025
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 10 Apr 2025
  
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  DOI: 10.1158/1541-7786.mcr-24-0957
  
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52.53.155.43/009f5d6e39c430064ce0b832cf798a7e9caafb80/PDF-html.html
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Fatty acid uptake activates an AXL–CAV1–β-catenin axis to drive melanoma progression

1
1. scibot 05 Apr 2025
  
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  DOI: 10.1101/gad.351985.124
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11960706/
Feb 2025
link.springer.com link.springer.com

AXL promotes lymphangiogenesis by amplifying VEGF-C-mediated AKT pathway

1
1. scibot 28 Feb 2025
  
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  RRID:AB_11217435
  
  DOI: 10.1007/s00018-024-05542-3
  
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link.springer.com/article/10.1007/s00018-024-05542-3
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription

1
1. scibot 26 Sep 2024
  
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  DOI: 10.1038/s44319-024-00217-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11387499/
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Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma

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1. scibot 12 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114721
  
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sciencedirect.com/science/article/pii/S2211124724010726
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A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.xcrm.2024.101703
  
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sciencedirect.com/science/article/pii/S2666379124004245
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread

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1. scibot 21 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114484
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11316253/
May 2024
52.53.155.43 52.53.155.43

Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation

1
1. scibot 04 May 2024
  
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  AB_11217435
  
  DOI: 10.1101/2024.01.21.576568
  
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52.53.155.43/5631ba0ece03be5b6bc39fba9c8a58e52d07c519/2024.01.21.576568v1.full-html.html
Apr 2024
aacrjournals.org aacrjournals.org

AXL/WRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2+ breast cancer

1
1. scibot 19 Apr 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-1459
  
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aacrjournals.org/cancerres/article/84/5/675/734930/AXL-WRNIP1-Mediates-Replication-Stress-Response
Aug 2023
52.53.155.43 52.53.155.43

L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab

2
1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.xcrm.2023.101142
  
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2. scibot 10 Aug 2023
  
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  RRID:AB_11217435
  
  DOI: 10.1016/j.xcrm.2023.101142
  
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52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
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Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer

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  DOI: 10.1016/j.ccell.2023.07.005
  
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sciencedirect.com/science/article/pii/S1535610823002453
Jun 2023
dx.doi.org dx.doi.org

LZTR1 mutation mediates oncogenesis through stabilization of EGFR and AXL

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1. scibot 08 Jun 2023
  
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  DOI: 10.1158/2159-8290.CD-22-0376
  
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dx.doi.org/10.1158/2159-8290.CD-22-0376
Feb 2023
52.53.155.43 52.53.155.43

cd-22-0376-html.html

1
1. scibot 17 Feb 2023
  
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  RRID:AB_11217435
  
  DOI: 10.1158/2159-8290.CD-22-0376
  
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52.53.155.43/a051cdc9b66cfe47aeb3f39770c1ce7cd380afb2/cd-22-0376-html.html
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CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance

1
1. scibot 16 Feb 2023
  
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  RRID:AB_11217435
  
  DOI: 10.1016/j.ccell.2023.01.007
  
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sciencedirect.com/science/article/pii/S1535610823000077
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Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

1
1. scibot 03 Feb 2023
  
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  RRID:AB_11217435
  
  DOI: 10.1016/j.molcel.2023.01.015
  
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sciencedirect.com/science/article/pii/S1097276523000382
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Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease

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1. scibot 03 Feb 2023
  
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  DOI: 10.1016/j.immuni.2023.01.008
  
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sciencedirect.com/science/article/pii/S1074761323000183
Jan 2023
aacrjournals.org aacrjournals.org

ER-001259851-000, a novel selective inhibitor of AXL, overcomes resistance to antimitotic drugs

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1. scibot 14 Jan 2023
  
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  RRID:AB_11217435
  
  DOI: 10.1158/1535-7163.MCT-21-0879
  
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aacrjournals.org/mct/article/22/1/12/711996/ER-851-a-Novel-Selective-Inhibitor-of-AXL
Aug 2022
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ABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brain

1
1. scibot 31 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111268
  
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sciencedirect.com/science/article/pii/S2211124722010865
Jul 2022
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Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity

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  DOI: 10.1016/j.ccell.2022.06.006
  
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sciencedirect.com/science/article/pii/S1535610822002707
Mar 2022
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AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells

1
1. scibot 18 Mar 2022
  
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  DOI: 10.1016/j.xcrm.2022.100554
  
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sciencedirect.com/science/article/pii/S266637912200060X
Feb 2022
www.sciencedirect.com www.sciencedirect.com

A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells

1
1. scibot 23 Feb 2022
  
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  DOI: 10.1016/j.molcel.2022.01.022
  
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sciencedirect.com/science/article/pii/S1097276522000879
Jan 2022
onlinelibrary.wiley.com onlinelibrary.wiley.com

SKI-G-801, an AXL kinase inhibitor, blocks metastasis through inducing anti-tumor immune responses and potentiates anti-PD-1 therapy in mouse cancer models

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1. scibot 05 Jan 2022
  
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  8661
  
  DOI: 10.1002/cti2.1364
  
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onlinelibrary.wiley.com/doi/10.1002/cti2.1364
Dec 2021
elifesciences.org elifesciences.org

BRAFV600E induces reversible mitotic arrest in human melanocytes via microrna-mediated suppression of AURKB

1
1. scibot 01 Dec 2021
  
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  DOI: 10.7554/eLife.70385
  
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elifesciences.org/articles/70385
Nov 2021
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FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma

1
1. scibot 03 Nov 2021
  
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  RRID:AB_11217435
  
  DOI: 10.1016/j.celrep.2021.109905
  
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The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway

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The effect of Zika virus infection in the ferret

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1. scibot 31 Jul 2021
  
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Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma

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Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells

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Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis

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Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

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Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity

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A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis

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The effect of Zika virus infection in the ferret

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OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ

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  DOI: 10.1016/j.molcel.2018.10.030
  
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Nov 2018
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Untitled document

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Systematic Functional Annotation of Somatic Mutations in Cancer

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Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress

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Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids

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