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  1. Last 7 days
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    Synthetic organizer cells guide development via spatial and biochemical instructions
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    1. scibot 21 Dec 2024
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    sciencedirect.com/science/article/pii/S0092867424013230
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    Generation and characterization of novel induced pluripotent stem cell (iPSC) lines derived from three symptomatic carriers of a pathogenic MYH11 variant and two non-carrier relatives
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    sciencedirect.com/science/article/pii/S1873506124003283
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    Generation of a genetically encoded voltage indicator MARINA reporter human iPS cell line using Cas9 (VULSCi002-A-2)
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  5. Dec 2024
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    Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate
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    sciencedirect.com/science/article/pii/S1534580724006993
  7. Sep 2024
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    mTOR activity paces human blastocyst stage developmental progression
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    Piplartine attenuates aminoglycoside-induced TRPV1 activity and protects from hearing loss in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11392653/
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    Human induced pluripotent stem cell line (FDHSi005-A) derived from a patient with a deep intronic variant in the GNE gene
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    sciencedirect.com/science/article/pii/S1873506124002605
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    Protocol for generating human cortical organoids enriched in outer radial glia by guided differentiation
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    sciencedirect.com/science/article/pii/S2666166724004453
  12. Aug 2024
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    Generating a human induced pluripotent stem cell line (XACHi018-A) from a Timothy syndrome infant carrying heterozygous CACNA1C c.1216G>A (p.G406R) mutation
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    sciencedirect.com/science/article/pii/S1873506124002113
  14. Jul 2024
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    Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation
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    sciencedirect.com/science/article/pii/S2666379124003732
  16. 52.53.155.43 52.53.155.43
    Substrate Stiffness Alters Layer Architecture and Biophysics of Human Induced Pluripotent Stem Cells to Modulate their Differentiation Potential
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  17. www.cell.com www.cell.com
    Human trophectoderm becomes multi-layered by internalization at the polar region
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      DOI: 10.1016/j.devcel.2024.05.028

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    cell.com/developmental-cell/abstract/S1534-5807(24)00362-9
  18. Jun 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inflammatory Response and Defects on Myelin Integrity in the Olfactory System of K18hACE2 Mice Infected with SARS-CoV-2
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      DOI: 10.1523/ENEURO.0106-24.2024

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    ncbi.nlm.nih.gov/pmc/articles/PMC11185043/
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    Bidirectional activation of stem-like programs between metastatic cancer and alveolar type 2 cells within the niche
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    Inhibition of HDAC activity directly reprograms murine embryonic stem cells to trophoblast stem cells
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    sciencedirect.com/science/article/pii/S1534580724003265
  22. May 2024
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    Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids
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    sciencedirect.com/science/article/pii/S1934590924001462
  24. Apr 2024
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    Mannose controls mesoderm specification and symmetry breaking in mouse gastruloids
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    Reprogramming fibroblast into human iBlastoids
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      DOI: 10.1038/s41596-024-00984-2

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    nature.com/articles/s41596-024-00984-2
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    Generation of human cerebral organoids with a structured outer subventricular zone
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    sciencedirect.com/science/article/pii/S2211124724003590
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    Protocol for generating mouse morula-like cells resembling 8- to 16-cell stage embryo cells
    2
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      DOI: 10.1016/j.xpro.2024.102934

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    sciencedirect.com/science/article/pii/S2666166724000996
  29. Mar 2024
  30. www.sciencedirect.com www.sciencedirect.com
    Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders
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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALK upregulates POSTN and WNT signaling to drive neuroblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11101011/
  32. Jan 2024
  33. www.sciencedirect.com www.sciencedirect.com
    Human fetal brain self-organizes into long-term expanding organoids
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  34. Dec 2023
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    Generation of two induced pluripotent stem cell lines from two sporadic amyotrophic lateral sclerosis patients
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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Shh from mossy cells contributes to preventing NSC pool depletion after seizure-induced neurogenesis and in aging
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      DOI: 10.7554/eLife.91263

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    ncbi.nlm.nih.gov/pmc/articles/PMC10712957/
  37. Nov 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Tsc2 coordinates neuroprogenitor differentiation
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    sciencedirect.com/science/article/pii/S2589004223025191
  39. Oct 2023
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    In vitro generation of mouse morula-like cells
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      DOI: 10.1016/j.devcel.2023.09.013

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  41. 52.53.155.43 52.53.155.43
    Embryo model completes gastrulation to neurulation and organogenesis
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      DOI: 10.1038/s41586-022-05246-3

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    52.53.155.43/97408a7bbb703adcbeedb4a1878d0ca4ae156bc9/s41596-023-00891-y (1)-html.html
  42. 52.53.155.43 52.53.155.43
    Transgene directed induction of a stem cell-derived human embryo model
    1
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      DOI: 10.1101/2023.06.15.545082

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    52.53.155.43/5a401c55d861c2dcc062c9d148face33c192a62e/2023.06.15.545082v1.full-html.html
  43. Aug 2023
  44. www.biorxiv.org www.biorxiv.org
    Shh from mossy cells contributes to preventing NSC pool depletion after seizure-induced neurogenesis and in aging
    1
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      DOI: 10.1101/2023.08.21.554173

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    biorxiv.org/content/10.1101/2023.08.21.554173v1
  45. Jul 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Organ function is preserved despite reorganization of niche architecture in the hair follicle
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      DOI: 10.1016/j.stem.2023.06.003

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    sciencedirect.com/science/article/pii/S193459092300214X
  47. Jun 2023
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deconstructing olfactory epithelium developmental pathways in olfactory neuroblastoma
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      DOI: 10.1158/2767-9764.CRC-23-0013

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    ncbi.nlm.nih.gov/pmc/articles/PMC10243222/
  49. May 2023
  50. www.sciencedirect.com www.sciencedirect.com
    Multimodal characterization of murine gastruloid development
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      DOI: 10.1016/j.stem.2023.04.018

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    sciencedirect.com/science/article/pii/S1934590923001704
  51. www.mdpi.com www.mdpi.com
    Hedgehog Signaling Pathway Orchestrates Human Lung Branching Morphogenesis
    1
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      DOI: 10.3390/ijms23095265

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    mdpi.com/1422-0067/23/9/5265/htm
  52. Apr 2023
  53. www.sciencedirect.com www.sciencedirect.com
    Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone
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      DOI: 10.1016/j.celrep.2023.112371

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    sciencedirect.com/science/article/pii/S2211124723003820
  54. Mar 2023
  55. www.sciencedirect.com www.sciencedirect.com
    The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool
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      DOI: 10.1016/j.celrep.2023.112242

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    sciencedirect.com/science/article/pii/S221112472300253X
  56. Jan 2023
  57. www.sciencedirect.com www.sciencedirect.com
    Controlling organoid symmetry breaking uncovers an excitable system underlying human axial elongation
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      DOI: 10.1016/j.cell.2022.12.043

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    sciencedirect.com/science/article/pii/S0092867422015860
  58. www.sciencedirect.com www.sciencedirect.com
    Controlling human organoid symmetry breaking reveals signaling gradients drive segmentation clock waves
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      DOI: 10.1016/j.cell.2022.12.042

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    sciencedirect.com/science/article/pii/S0092867422015859
  59. Oct 2022
  60. www.sciencedirect.com www.sciencedirect.com
    Generation of two heterozygous GAA mutation-carrying human induced pluripotent stem cell lines (XACHi005-A, XACHi006-A) from parents of an infant with Pompe disease
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  61. Sep 2022
  62. www.sciencedirect.com www.sciencedirect.com
    Generation of knock-in degron tags for endogenous proteins in mice using the dTAG system
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  63. www.sciencedirect.com www.sciencedirect.com
    Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development
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  64. Jun 2022
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model
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  66. Apr 2022
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oral and Injected Tamoxifen Alter Adult Hippocampal Neurogenesis in Female and Male Mice
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  68. www.sciencedirect.com www.sciencedirect.com
    Progenitor potential of lung epithelial organoid cells in a transplantation model
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  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Integrated age-related immunohistological changes occur in human olfactory epithelium and olfactory bulb
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  70. Feb 2022
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of the neurogenic niche in the aging dentate gyrus using iterative immunofluorescence imaging
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  72. Jan 2022
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects
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  74. Nov 2021
  75. www.sciencedirect.com www.sciencedirect.com
    Modulating mesendoderm competence during human germ layer differentiation
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  76. Sep 2021
  77. www.sciencedirect.com www.sciencedirect.com
    Visualization of individual cell division history in complex tissues using iCOUNT
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  78. Aug 2021
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  80. Jul 2021
  81. dev.biologists.org dev.biologists.org
    Yap and its subcellular localization have distinct compartment-specific roles in the developing lung
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      rat anti-Sox2

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  82. Jun 2021
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative analysis of signaling responses during mouse primordial germ cell specification
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      DOI: 10.1242/bio.058741

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  84. May 2021
  85. elifesciences.org elifesciences.org
    The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos
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      RRID:AB_11219471

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  86. www.sciencedirect.com www.sciencedirect.com
    Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population
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      RRID:AB_11219471

      DOI: 10.1016/j.devcel.2020.10.014

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  87. Apr 2021
  88. www.sciencedirect.com www.sciencedirect.com
    Declining lamin B1 expression mediates age-dependent decreases of hippocampal stem cell activity
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      RRID:AB_11219471

      DOI: 10.1016/j.stem.2021.01.015

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  89. Feb 2021
  90. www.sciencedirect.com www.sciencedirect.com
    Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population
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      RRID:AB_11219471

      DOI: 10.1016/j.stem.2021.01.003

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    sciencedirect.com/science/article/pii/S1934590921000035
  91. Jan 2021
  92. www.sciencedirect.com www.sciencedirect.com
    Establishment of human embryonic stem cell WAe009-A-48 carrying a Long QT syndrome mutation in SCN5A
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      RRID:AB_11219471

      DOI: 10.1016/j.scr.2021.102194

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    sciencedirect.com/science/article/pii/S1873506121000404
  93. Dec 2020
  94. www.sciencedirect.com www.sciencedirect.com
    Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency
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      RRID:AB_11219471

      DOI: 10.1016/j.stem.2020.11.005

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    sciencedirect.com/science/article/pii/S1934590920305439
  95. Nov 2020
  96. onlinelibrary.wiley.com onlinelibrary.wiley.com
    An epilepsy‐associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model
    1
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      RRID:AB_11219471

      DOI: 10.1002/jnr.24747

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  97. Sep 2020
  98. www.sciencedirect.com www.sciencedirect.com
    Generation of a human embryonic stem cell line (WAe009-A-43) carrying a Long QT syndrome related mutation in KCNH2 gene
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    1. scibot 05 Sep 2020
      RRID:AB_11219471

      DOI: 10.1016/j.scr.2020.101976

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    sciencedirect.com/science/article/pii/S1873506120302774
  99. Jan 2020
  100. www.sciencedirect.com www.sciencedirect.com
    Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation
    1
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      RRID:AB_11219471

      DOI: 10.1016/j.devcel.2019.11.002

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    sciencedirect.com/science/article/pii/S1534580719309104
  101. www.jneurosci.org www.jneurosci.org
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      AB_11219471

      DOI: 10.1523/JNEUROSCI.3261-17.2018

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    jneurosci.org/content/38/31/6806
  102. Nov 2018
  103. www.sciencedirect.com www.sciencedirect.com
    3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
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  104. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1534580718301588
  105. europepmc.org europepmc.org
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning
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      Curator: @evieth

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  107. europepmc.org europepmc.org
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