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Local delivery of IL-15 and anti-PD-L1 nanobody by in vitro-transcribed circILNb elicits superior antitumor immunity in cold tumors

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1. scibot 11 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102413
  
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sciencedirect.com/science/article/pii/S2666379125004860
Sep 2025
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Zeaxanthin augments CD8+ effector T cell function and immunotherapy efficacy

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102324
  
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sciencedirect.com/science/article/pii/S2666379125003970
May 2025
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Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.030
  
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sciencedirect.com/science/article/pii/S1074761325001931
Sep 2024
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Glioblastoma induces the recruitment and differentiation of dendritic-like “hybrid” neutrophils from skull bone marrow

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.ccell.2024.08.008
  
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sciencedirect.com/science/article/pii/S1535610824003076
Feb 2024
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EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas

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1. scibot 15 Feb 2024
  
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  DOI: 10.1158/2767-9764.CRC-23-0399
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10863487/
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Mice Generated with Induced Pluripotent Stem Cells Derived from Mucosal-Associated Invariant T Cells

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1. scibot 01 Feb 2024
  
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  DOI: 10.3390/biomedicines12010137
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10813358/
Jan 2024
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Fc-fused IL-7 provides broad antiviral effects against respiratory virus infections through IL-17A-producing pulmonary innate-like T cells

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1. scibot 21 Jan 2024
  
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  DOI: 10.1016/j.xcrm.2023.101362
  
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sciencedirect.com/science/article/pii/S2666379123005797
Dec 2023
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The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer

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1. scibot 02 Dec 2023
  
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  DOI: 10.1016/j.immuni.2023.11.002
  
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sciencedirect.com/science/article/pii/S1074761323004831
Nov 2023
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Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity

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1. scibot 25 Nov 2023
  
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  DOI: 10.1038/s41586-023-06749-3
  
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nature.com/articles/s41586-023-06749-3
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A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression

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1. scibot 17 Nov 2023
  
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  DOI: 10.1016/j.devcel.2023.10.010
  
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sciencedirect.com/science/article/pii/S1534580723005518
Aug 2023
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PIIS2211124723009622-html.html

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112951
  
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52.53.155.43/ab78471f0bcea9a54e77e384546909131002deb2/PIIS2211124723009622-html.html
Apr 2023
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cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory

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1. scibot 05 Apr 2023
  
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  DOI: 10.1126/sciimmunol.abq7432
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9835709/
Feb 2023
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Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer

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1. scibot 24 Feb 2023
  
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  DOI: 10.1016/j.ccell.2023.01.004
  
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sciencedirect.com/science/article/pii/S1535610823000041
Jan 2023
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Ablation of Adar1 in myeloid cells imprints a global antiviral state in the lung and heightens early immunity against SARS-CoV-2

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1. scibot 27 Jan 2023
  
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  DOI: 10.1016/j.celrep.2023.112038
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9842623/
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Protocol to assess the antitumor efficacy of an immunotherapeutic peptide in syngeneic orthotopic glioma mouse models

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1. scibot 21 Jan 2023
  
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  DOI: 10.1016/j.xpro.2023.102049
  
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sciencedirect.com/science/article/pii/S2666166723000072
Nov 2022
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A tick C1q protein alters infectivity of the Lyme disease agent by modulating interferon γ

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1. scibot 24 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111673
  
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sciencedirect.com/science/article/pii/S2211124722015479
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Chronic type I interferon signaling promotes lipid-peroxidation-driven terminal CD8+ T cell exhaustion and curtails anti-PD-1 efficacy

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1. scibot 16 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111647
  
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sciencedirect.com/science/article/pii/S2211124722015182
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The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity

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1. scibot 15 Nov 2022
  
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  DOI: 10.1016/j.immuni.2022.10.020
  
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sciencedirect.com/science/article/pii/S1074761322005611
Sep 2022
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Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease

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1. scibot 22 Sep 2022
  
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  DOI: 10.1016/j.chom.2022.08.018
  
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sciencedirect.com/science/article/pii/S1931312822004176
Jul 2022
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mTORC1 signaling in antigen-presenting cells of the skin restrains CD8+ T cell priming

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1. scibot 06 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111032
  
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sciencedirect.com/science/article/pii/S2211124722008269
May 2022
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Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity

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1. scibot 12 May 2022
  
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  DOI: 10.1016/j.ccell.2022.04.004
  
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sciencedirect.com/science/article/pii/S1535610822001660
Feb 2022
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Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target

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1. scibot 17 Feb 2022
  
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  DOI: 10.1038/s41467-022-28372-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8828877/
Sep 2021
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In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target

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1. scibot 28 Sep 2021
  
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  DOI: 10.1016/j.cell.2021.09.006
  
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Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development

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1. scibot 24 Sep 2021
  
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  DOI: 10.1016/j.stem.2020.08.004
  
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sciencedirect.com/science/article/pii/S1934590920304008
Aug 2021
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CXCL10/CXCR3 signaling contributes to an inflammatory microenvironment and its blockade enhances progression of murine pancreatic precancerous lesions

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1. scibot 19 Aug 2021
  
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  DOI: 10.7554/eLife.60646
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8360647/
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The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression

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1. scibot 09 Aug 2021
  
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  DOI: 10.1016/j.immuni.2018.10.013
  
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sciencedirect.com/science/article/pii/S1074761318304783
Jul 2021
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Untitled document

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  DOI: 10.1016/j.immuni.2018.08.017
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6162341/
May 2021
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Adoptive T Cell Therapy Targeting Different Gene Products Reveals Diverse and Context-Dependent Immune Evasion in Melanoma

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1. scibot 06 May 2021
  
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  DOI: 10.1016/j.immuni.2020.07.007
  
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sciencedirect.com/science/article/pii/S1074761320303149
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Core liver homeostatic co-expression networks are preserved but respond to perturbations in an organism- and disease-specific manner

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  DOI: 10.1016/j.cels.2021.04.004
  
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sciencedirect.com/science/article/pii/S2405471221001137
Nov 2020
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Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development

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1. scibot 27 Nov 2020
  
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  DOI: DOI:10.1016/j.stem.2020.08.004
  
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sciencedirect.com/science/article/pii/S1934590920304008
Jan 2020
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Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.10.010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6892583/
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N6-Methyladenosine Modification Controls Circular RNA Immunity

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2019.07.016
  
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sciencedirect.com/science/article/pii/S1097276519305465
Nov 2018
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Untitled document

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1. scibot 05 Nov 2018
  
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IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S2405471218302382