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Uncovering the individual immunotherapeutic roles of PTPN1 and PTPN2 in T cells during dual inhibition

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1. scibot 15 Oct 2025
  
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  DOI: 10.1016/j.isci.2025.113610
  
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sciencedirect.com/science/article/pii/S2589004225018711
Jun 2025
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Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy

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1. scibot 03 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.006
  
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sciencedirect.com/science/article/pii/S1074761325002274
May 2025
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Stress-induced pro-inflammatory glioblastoma stem cells secrete TNFAIP6 to enhance tumor growth and induce suppressive macrophages

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1. scibot 22 May 2025
  
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  DOI: 10.1016/j.devcel.2025.04.027
  
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sciencedirect.com/science/article/pii/S1534580725002874
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Memory T‐Cell Phenotype in Cutaneous T‐Cell Lymphoma Is Modified by Germline Gene Gametocyte Specific Factor 1

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1. scibot 20 May 2025
  
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  DOI: 10.1111/exd.70123
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12078864/
Mar 2025
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Phosphatase PHLPP1 is an alveolar-macrophage-intrinsic transcriptional checkpoint controlling pulmonary fibrosis

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1. scibot 13 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115399
  
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sciencedirect.com/science/article/pii/S2211124725001706
Feb 2025
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Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

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1. scibot 11 Feb 2025
  
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  DOI: 10.1016/j.ccell.2025.01.004
  
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sciencedirect.com/science/article/pii/S1535610825000224
Aug 2024
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Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression

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1. scibot 28 Aug 2024
  
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  DOI: 10.1016/j.devcel.2024.08.003
  
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sciencedirect.com/science/article/pii/S1534580724004866
Apr 2024
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25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages

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1. scibot 19 Apr 2024
  
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  DOI: 10.1016/j.immuni.2024.03.021
  
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sciencedirect.com/science/article/pii/S1074761324001420
Jan 2024
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Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging

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1. scibot 23 Jan 2024
  
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  DOI: 10.1016/j.immuni.2024.01.001
  
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sciencedirect.com/science/article/pii/S1074761324000268
Oct 2023
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High-throughput identification of Toxoplasma gondii effector proteins that target host cell transcription

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1. scibot 13 Oct 2023
  
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  RRID:AB_11220421
  
  DOI: 10.1016/j.chom.2023.09.003
  
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sciencedirect.com/science/article/pii/S1931312823003700
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cyclo (MQCNS) has the potential to treat ischemic stroke

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1. scibot 25 Jul 2023
  
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  RRID:AB_11220421
  
  DOI: 10.4103/1673-5374.371367
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10360098/
May 2023
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MTHFD2 reprograms macrophage polarization by inhibiting PTEN

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1. scibot 11 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112481
  
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sciencedirect.com/science/article/pii/S2211124723004928
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The glycolysis/HIF-1α axis defines the inflammatory role of IL-4-primed macrophages

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1. scibot 11 May 2023
  
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  RRID:AB_11220421
  
  DOI: 10.1016/j.celrep.2023.112471
  
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sciencedirect.com/science/article/pii/S2211124723004825
Apr 2023
aacrjournals.org aacrjournals.org

CD142 Identifies Neoplastic Desmoid Tumor Cells, Uncovering Interactions Between Neoplastic and Stromal Cells That Drive Proliferation

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1. scibot 28 Apr 2023
  
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  DOI: 10.1158/2767-9764.CRC-22-0403
  
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aacrjournals.org/cancerrescommun/article/3/4/697/726086/CD142-Identifies-Neoplastic-Desmoid-Tumor-Cells
Jan 2023
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 14 Jan 2023
  
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  RRID:AB_11220421
  
  DOI: 10.1111/bph.15993
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15993
Nov 2022
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FABP5 controls macrophage alternative activation and allergic asthma by selectively programming long-chain unsaturated fatty acid metabolism

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1. scibot 16 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111668
  
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sciencedirect.com/science/article/pii/S221112472201542X
Sep 2022
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Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance

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1. scibot 11 Sep 2022
  
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  RRID:AB_11220421
  
  DOI: 10.1016/j.ccell.2022.08.012
  
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sciencedirect.com/science/article/pii/S1535610822003762
Aug 2022
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STAT6 in mitochondrial outer membrane impairs mitochondrial fusion by inhibiting MFN2 dimerization

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1. scibot 30 Aug 2022
  
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  RRID:AB_11220421
  
  DOI: 10.1016/j.isci.2022.104923
  
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sciencedirect.com/science/article/pii/S2589004222011956
Apr 2022
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Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C

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1. scibot 09 Apr 2022
  
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  DOI: 10.1016/j.immuni.2022.03.009
  
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sciencedirect.com/science/article/pii/S1074761322001327
Mar 2022
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PTIP governs NAD+ metabolism by regulating CD38 expression to drive macrophage inflammation

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1. scibot 31 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110603
  
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sciencedirect.com/science/article/pii/S2211124722003515
onlinelibrary.wiley.com onlinelibrary.wiley.com

BET protein inhibition in macrophages enhances dorsal root ganglion neurite outgrowth in female mice

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1. scibot 01 Mar 2022
  
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  DOI: 10.1002/jnr.25036
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.25036
Oct 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RSV infection-elicited high MMP-12–producing macrophages exacerbate allergic airway inflammation with neutrophil infiltration

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1. scibot 28 Oct 2021
  
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  DOI: 10.1016/j.isci.2021.103201
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8524145/
May 2021
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An active marine halophenol derivative attenuates lipopolysaccharide-induced acute liver injury in mice by improving M2 macrophage-mediated therapy

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1. scibot 29 May 2021
  
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  RRID:AB_11220421
  
  DOI: 10.1016/j.intimp.2021.107676
  
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sciencedirect.com/science/article/pii/S156757692100312X
Dec 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions

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1. scibot 09 Dec 2020
  
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  RRID:AB_11220421
  
  DOI: 10.1093/hmg/ddaa209
  
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  RRID:AB_11220421 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7689298/
Jan 2020
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Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses

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1. scibot 13 Jan 2020
  
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  RRID:AB_11220421
  
  DOI: 10.1016/j.immuni.2019.06.007
  
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  RRID:AB_11220421 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761319302778
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A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.ccell.2019.10.002
  
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sciencedirect.com/science/article/pii/S1535610819304763