58 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Mutant FOXO1 controls an oncogenic network via enhancer accessibility
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    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.xgen.2024.100537

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    sciencedirect.com/science/article/pii/S2666979X24000934
  3. Mar 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide
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    1. scibot 08 Mar 2024
      Santa CruzSc-73614; RRID:AB_1131294

      DOI: 10.1016/j.molcel.2023.12.033

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    sciencedirect.com/science/article/pii/S1097276523010791
  5. Feb 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a First-in-Class Small Molecule Inhibitor of the eIF4E-RBM38 Complex that Enhances wild-type p53 Protein Translation for Tumor Growth Suppression
    1
    1. scibot 16 Feb 2024
      RRID:AB_1131294

      DOI: 10.1158/1535-7163.MCT-22-0627

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    ncbi.nlm.nih.gov/pmc/articles/PMC10866396/
  7. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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    1. scibot 09 Feb 2024
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      DOI: 10.1101/2023.12.05.570182

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    2. scibot 09 Feb 2024
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      DOI: 10.1101/2023.12.05.570182

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    3. scibot 09 Feb 2024
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      DOI: 10.1101/2023.12.05.570182

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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  8. Nov 2023
  9. www.sciencedirect.com www.sciencedirect.com
    RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks
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    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.molcel.2023.10.012

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    sciencedirect.com/science/article/pii/S1097276523008493
  10. www.biorxiv.org www.biorxiv.org
    Recruitment of FBXO22 for Targeted Degradation of NSD2
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    1. scibot 10 Nov 2023
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      DOI: 10.1101/2023.11.01.564830

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    biorxiv.org/content/10.1101/2023.11.01.564830v1
  11. www.embopress.org www.embopress.org
    SIRT2 negatively regulates the cGAS-STING pathway by deacetylating G3BP1
    1
    1. scibot 03 Nov 2023
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      DOI: 10.15252/embr.202357500

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    embopress.org/doi/10.15252/embr.202357500
  12. Oct 2023
  13. www.sciencedirect.com www.sciencedirect.com
    Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.cell.2023.09.024

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    sciencedirect.com/science/article/pii/S0092867423010784
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    Universal features of Nsp1-mediated translational shutdown by coronaviruses
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    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.molcel.2023.09.002

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    sciencedirect.com/science/article/abs/pii/S1097276523006974
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    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
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    1. scibot 13 Oct 2023
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    sciencedirect.com/science/article/pii/S1097276523007025
  16. www.cell.com www.cell.com
    ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113099

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    cell.com/cell-reports/abstract/S2211-1247(23)01110-5
  17. Aug 2023
  18. www.sciencedirect.com www.sciencedirect.com
    The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
    1
    1. scibot 05 Aug 2023
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      DOI: 10.1016/j.isci.2023.107449

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    sciencedirect.com/science/article/pii/S2589004223015262
  19. Jul 2023
  20. 52.53.155.43 52.53.155.43
    Mapping Pregnancy-dependent Sulfhydrome Unfolds Diverse Functions of Protein Sulfhydration in Human Uterine Artery
    1
    1. scibot 15 Jul 2023
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      DOI: 10.1210/endocr/bqad107

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    52.53.155.43/0669a8fe0018bbe1ec8eb04faabbfdad366bc9e2/bqad107-html.html
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    Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin
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    1. scibot 06 Jul 2023
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      DOI: 10.1016/j.immuni.2023.06.006

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    sciencedirect.com/science/article/pii/S1074761323002637
  22. Jun 2023
  23. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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    1. scibot 28 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.047

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    sciencedirect.com/science/article/pii/S0092867423005986
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.cmet.2023.05.007

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    sciencedirect.com/science/article/pii/S1550413123001845
  25. www.sciencedirect.com www.sciencedirect.com
    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
    1
    1. scibot 09 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112616

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    sciencedirect.com/science/article/pii/S2211124723006277
  26. May 2023
  27. www.sciencedirect.com www.sciencedirect.com
    ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis
    1
    1. scibot 31 May 2023
      RRID:AB_1131294

      DOI: 10.1016/j.celrep.2023.112562

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    sciencedirect.com/science/article/pii/S2211124723005739
  28. Apr 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
    1
    1. scibot 21 Apr 2023
      RRID:AB_1131294

      DOI: 10.1158/1078-0432.CCR-22-2977

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    ncbi.nlm.nih.gov/pmc/articles/PMC10102842/
  30. Feb 2023
  31. aacrjournals.org aacrjournals.org
    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
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    1. scibot 10 Feb 2023
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      DOI: 10.1158/0008-5472.CAN-22-1533

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    aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
  32. Jan 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
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    1. scibot 20 Jan 2023
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      DOI: 10.1158/0008-5472.CAN-21-3217

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    ncbi.nlm.nih.gov/pmc/articles/PMC9298960/
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    The human pre-replication complex is an open complex
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      DOI: 10.1016/j.cell.2022.12.008

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    sciencedirect.com/science/article/pii/S0092867422015215
  35. Dec 2022
  36. aacrjournals.org aacrjournals.org
    Raptinal induces Gasdermin E-dependent pyroptosis in naive and therapy-resistant melanoma
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    1. scibot 04 Dec 2022
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      DOI: 10.1158/1541-7786.MCR-22-0040

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    aacrjournals.org/mcr/article/20/12/1811/711004/Raptinal-Induces-Gasdermin-E-Dependent-Pyroptosis
  37. Nov 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
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      DOI: 10.1158/0008-5472.CAN-22-0671

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    ncbi.nlm.nih.gov/pmc/articles/PMC9437574/
  39. Oct 2022
  40. 52.53.155.43 52.53.155.43
    mcr-22-0040-html.html
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      DOI: 10.1158/1541-7786.MCR-22-0040

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    52.53.155.43/727478f306d650986e0e949733013801988f63e4/mcr-22-0040-html.html
  41. Aug 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Pituitary adenomas evade apoptosis via noxa deregulation in Cushing’s disease
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    1. scibot 26 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111223

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    sciencedirect.com/science/article/pii/S2211124722010403
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    Chromosome silencing in vitro reveals trisomy 21 causes cell-autonomous deficits in angiogenesis and early dysregulation in Notch signaling
    1
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      DOI: 10.1016/j.celrep.2022.111174

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    sciencedirect.com/science/article/pii/S2211124722009871
  44. Jul 2022
  45. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 29 Jul 2022
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      DOI: 10.1111/bph.15904

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15904
  46. Mar 2022
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TIGAR deficiency enhances skeletal muscle thermogenesis by increasing neuromuscular junction cholinergic signaling
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      DOI: 10.7554/eLife.73360

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    ncbi.nlm.nih.gov/pmc/articles/PMC8947760/
  48. academic.oup.com academic.oup.com
    Circulating MicroRNA Profiles as Potential Biomarkers for differentiated thyroid cancer recurrence
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      DOI: 10.1210/clinem/dgac009

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac009/6503735
  49. www.sciencedirect.com www.sciencedirect.com
    Full-length and split-NanoLuc reporters identify pathogenic COL4A5 nonsense mutations susceptible to premature termination codon readthrough
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      DOI: 10.1016/j.isci.2022.103891

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    sciencedirect.com/science/article/pii/S2589004222001614
  50. Feb 2022
  51. www.sciencedirect.com www.sciencedirect.com
    Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants
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      DOI: 10.1016/j.celrep.2022.110322

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      DOI: 10.1016/j.celrep.2022.110322

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    sciencedirect.com/science/article/pii/S221112472200033X
  52. Nov 2021
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AXL cooperates with EGFR to mediate neutrophil elastase-induced migration of prostate cancer cells
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      DOI: 10.1016/j.isci.2021.103270

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    ncbi.nlm.nih.gov/pmc/articles/PMC8567381/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
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    1. scibot 05 Nov 2021
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      DOI: 10.7554/eLife.57462

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    ncbi.nlm.nih.gov/pmc/articles/PMC8555985/
  55. Oct 2021
  56. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Interleukin 6 reduces vascular smooth muscle cell apoptosis via Prep1 and is associated with aging
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      DOI: 10.1096/fj.202100943R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100943R
  57. Sep 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction
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      DOI: 10.1016/j.immuni.2021.09.001

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    sciencedirect.com/science/article/pii/S1074761321003642
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function
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    1. scibot 18 Sep 2021
      RRID:AB_1131294

      DOI: 10.7554/eLife.69269

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    ncbi.nlm.nih.gov/pmc/articles/PMC8439652/
  60. Aug 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Chemo-proteomics exploration of HDAC degradability by small molecule degraders
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      DOI: 10.1016/j.chembiol.2021.07.002

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    sciencedirect.com/science/article/pii/S2451945621003123
  62. Jul 2021
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Effects of the Antifungal Agent Ciclopirox in HPV‐Positive Cancer Cells: Repression of Viral E6/E7 Oncogene Expression and Induction of Senescence and Apoptosis
    1
    1. scibot 31 Jul 2021
      mouse anti‐Vinculin

      DOI: 10.1002/ijc.32709

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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32709
  64. academic.oup.com academic.oup.com
    Autophagy inhibition as a promising therapeutic target for laryngeal cancer
    1
    1. scibot 30 Jul 2021
      Anti-Vinculin

      DOI: 10.1093/carcin/bgz080

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    academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgz080/5485218
  65. pubs.acs.org pubs.acs.org
    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
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      RRID:AB_1131294

      DOI: 10.1021/acsptsci.9b00001

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  66. www.sciencedirect.com www.sciencedirect.com
    Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell
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    1. scibot 07 Jul 2021
      RRID:AB_1131294

      DOI: 10.1016/j.celrep.2021.109364

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    sciencedirect.com/science/article/pii/S2211124721007622
  67. Mar 2021
  68. www.sciencedirect.com www.sciencedirect.com
    A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection
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    1. scibot 17 Mar 2021
      RRID:AB_1131294

      DOI: 10.1016/j.celrep.2021.108859

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  69. Feb 2021
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
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    1. scibot 25 Feb 2021
      RRID:AB_1131294

      DOI: 10.1021/acsptsci.9b00001

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  71. Jan 2021
  72. www.sciencedirect.com www.sciencedirect.com
    A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans
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    1. scibot 05 Jan 2021
      RRID:AB_1131294

      DOI: 10.1016/j.celrep.2020.108559

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    sciencedirect.com/science/article/pii/S2211124720315485
  73. Nov 2020
  74. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TSPAN1: A Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance
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    1. scibot 11 Nov 2020
      Vinculin

      DOI: 10.3390/cancers12113269

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    pubmed.ncbi.nlm.nih.gov/33167355/
  75. Sep 2020
  76. www.sciencedirect.com www.sciencedirect.com
    Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses
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    1. scibot 14 Sep 2020
      RRID:AB_1131294

      DOI: 10.1016/j.celrep.2019.12.028

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    sciencedirect.com/science/article/pii/S221112471931678X
  77. www.sciencedirect.com www.sciencedirect.com
    Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module
    1
    1. scibot 09 Sep 2020
      RRID:AB_1131294

      DOI: 10.1016/j.celrep.2020.01.024

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    sciencedirect.com/science/article/pii/S2211124720300334
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of different L1 isoforms of Mastomys natalensis papillomavirus as mechanism to circumvent adaptive immunity
    1
    1. scibot 08 Sep 2020
      RRID:AB_1131294

      DOI: 10.7554/eLife.57626

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    ncbi.nlm.nih.gov/pmc/articles/PMC7402679/
  79. www.jneurosci.org www.jneurosci.org
    Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development
    1
    1. scibot 03 Sep 2020
      anti-vinculin

      DOI: 10.1523/JNEUROSCI.1707-19.2020

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    jneurosci.org/content/40/25/4824
  80. Jan 2020
  81. www.sciencedirect.com www.sciencedirect.com
    A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas
    1
    1. scibot 13 Jan 2020
      RRID:AB_1131294

      DOI: 10.1016/j.devcel.2019.07.022

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    sciencedirect.com/science/article/pii/S1534580719306288
  82. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_1131294

      DOI: 10.1016/j.devcel.2019.04.014

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    sciencedirect.com/science/article/pii/S1534580719302849
  83. www.sciencedirect.com www.sciencedirect.com
    Decreased Expression of Cilia Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Humans
    1
    1. scibot 13 Jan 2020
      RRID:AB_1131294

      DOI: 10.1016/j.celrep.2019.02.056

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    sciencedirect.com/science/article/pii/S2211124719302359
  84. Nov 2017
  85. www.sciencedirect.com www.sciencedirect.com
    Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function
    1
    1. scibot 08 Nov 2017
      RRID:AB_1131294

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1535610817304063