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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma
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      DOI: 10.1038/s44318-024-00299-8

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    pmc.ncbi.nlm.nih.gov/articles/PMC11649786/
  3. Nov 2024
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    Altered sphingolipid biosynthetic flux and lipoprotein trafficking contribute to trans-fat-induced atherosclerosis
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    sciencedirect.com/science/article/pii/S1550413124004121
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    Degradome analysis to identify direct protein substrates of small-molecule degraders
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  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dynamic roles of neutrophil extracellular traps in cancer cell adhesion and activation of Notch 1-mediated epithelial-to-mesenchymal transition in EGFR-driven lung cancer cells
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  7. Sep 2024
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    BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer
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      DOI: 10.1210/clinem/dgae589

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgae589/7740915
  9. Aug 2024
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    Microgravity Induces Transient EMT in Human Keratinocytes by Early Down-Regulation of E-Cadherin and Cell-Adhesion Remodeling
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      mouse anti vinculin

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  11. Jul 2024
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    Identification of the main barriers to Ku accumulation in chromatin
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    TP53INP2-dependent activation of muscle autophagy ameliorates sarcopenia and promotes healthy aging
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    A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer
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    cell.com/cell-chemical-biology/fulltext/S2451-9456(24)00273-3
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    FANCM promotes PARP inhibitor resistance by minimizing ssDNA gap formation and counteracting resection inhibition
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    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
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    Label-free three-dimensional imaging and quantitative analysis of living fibroblasts and myofibroblasts by holotomographic microscopy
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    1. scibot 16 Jul 2024
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      DOI: 10.1002/jemt.24648

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  18. Jun 2024
  19. link.springer.com link.springer.com
    Electro-elution-based purification of covalent DNA–protein cross-links
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      DOI: 10.1038/s41596-024-01004-z

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    An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors
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    The ribotoxic stress response drives UV-mediated cell death
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  22. May 2024
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    Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma
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      SANTA CRUZ BIOTECHNOLOGYCat#sc-73614

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    CDK4/6 activity is required during G2 arrest to prevent stress-induced endoreplication
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    PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer
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  26. Apr 2024
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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      DOI: 10.1093/narcan/zcae018

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    Mutant FOXO1 controls an oncogenic network via enhancer accessibility
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  29. Mar 2024
  30. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide
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      Santa CruzSc-73614; RRID:AB_1131294

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  31. Feb 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a First-in-Class Small Molecule Inhibitor of the eIF4E-RBM38 Complex that Enhances wild-type p53 Protein Translation for Tumor Growth Suppression
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  33. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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  34. Nov 2023
  35. www.sciencedirect.com www.sciencedirect.com
    RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks
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  36. www.biorxiv.org www.biorxiv.org
    Recruitment of FBXO22 for Targeted Degradation of NSD2
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  37. www.embopress.org www.embopress.org
    SIRT2 negatively regulates the cGAS-STING pathway by deacetylating G3BP1
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      DOI: 10.15252/embr.202357500

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  38. Oct 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria
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    Universal features of Nsp1-mediated translational shutdown by coronaviruses
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    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
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  42. www.cell.com www.cell.com
    ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct
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    cell.com/cell-reports/abstract/S2211-1247(23)01110-5
  43. Aug 2023
  44. www.sciencedirect.com www.sciencedirect.com
    The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
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      DOI: 10.1016/j.isci.2023.107449

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    sciencedirect.com/science/article/pii/S2589004223015262
  45. Jul 2023
  46. 52.53.155.43 52.53.155.43
    Mapping Pregnancy-dependent Sulfhydrome Unfolds Diverse Functions of Protein Sulfhydration in Human Uterine Artery
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      DOI: 10.1210/endocr/bqad107

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    Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin
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      DOI: 10.1016/j.immuni.2023.06.006

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  48. Jun 2023
  49. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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      DOI: 10.1016/j.cell.2023.05.047

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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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      DOI: 10.1016/j.cmet.2023.05.007

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    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
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    sciencedirect.com/science/article/pii/S2211124723006277
  52. May 2023
  53. www.sciencedirect.com www.sciencedirect.com
    ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis
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      DOI: 10.1016/j.celrep.2023.112562

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    sciencedirect.com/science/article/pii/S2211124723005739
  54. Apr 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
    1
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      RRID:AB_1131294

      DOI: 10.1158/1078-0432.CCR-22-2977

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  56. Feb 2023
  57. aacrjournals.org aacrjournals.org
    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
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      RRID:AB_1131294

      DOI: 10.1158/0008-5472.CAN-22-1533

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    aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
  58. Jan 2023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
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      DOI: 10.1158/0008-5472.CAN-21-3217

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  60. www.sciencedirect.com www.sciencedirect.com
    The human pre-replication complex is an open complex
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      DOI: 10.1016/j.cell.2022.12.008

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  61. Dec 2022
  62. aacrjournals.org aacrjournals.org
    Raptinal induces Gasdermin E-dependent pyroptosis in naive and therapy-resistant melanoma
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  63. Nov 2022
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
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  65. Oct 2022
  66. 52.53.155.43 52.53.155.43
    mcr-22-0040-html.html
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  67. Aug 2022
  68. www.sciencedirect.com www.sciencedirect.com
    Pituitary adenomas evade apoptosis via noxa deregulation in Cushing’s disease
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    Chromosome silencing in vitro reveals trisomy 21 causes cell-autonomous deficits in angiogenesis and early dysregulation in Notch signaling
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  70. Jul 2022
  71. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  72. Mar 2022
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TIGAR deficiency enhances skeletal muscle thermogenesis by increasing neuromuscular junction cholinergic signaling
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  74. academic.oup.com academic.oup.com
    Circulating MicroRNA Profiles as Potential Biomarkers for differentiated thyroid cancer recurrence
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      DOI: 10.1210/clinem/dgac009

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  75. www.sciencedirect.com www.sciencedirect.com
    Full-length and split-NanoLuc reporters identify pathogenic COL4A5 nonsense mutations susceptible to premature termination codon readthrough
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  76. Feb 2022
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    Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants
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  78. Nov 2021
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AXL cooperates with EGFR to mediate neutrophil elastase-induced migration of prostate cancer cells
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    TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
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      DOI: 10.7554/eLife.57462

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  81. Oct 2021
  82. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Interleukin 6 reduces vascular smooth muscle cell apoptosis via Prep1 and is associated with aging
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      DOI: 10.1096/fj.202100943R

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  83. Sep 2021
  84. www.sciencedirect.com www.sciencedirect.com
    Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction
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      DOI: 10.1016/j.immuni.2021.09.001

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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function
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      DOI: 10.7554/eLife.69269

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  86. Aug 2021
  87. www.sciencedirect.com www.sciencedirect.com
    Chemo-proteomics exploration of HDAC degradability by small molecule degraders
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      DOI: 10.1016/j.chembiol.2021.07.002

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    sciencedirect.com/science/article/pii/S2451945621003123
  88. Jul 2021
  89. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Effects of the Antifungal Agent Ciclopirox in HPV‐Positive Cancer Cells: Repression of Viral E6/E7 Oncogene Expression and Induction of Senescence and Apoptosis
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      mouse anti‐Vinculin

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  90. academic.oup.com academic.oup.com
    Autophagy inhibition as a promising therapeutic target for laryngeal cancer
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      Anti-Vinculin

      DOI: 10.1093/carcin/bgz080

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  91. pubs.acs.org pubs.acs.org
    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
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      DOI: 10.1021/acsptsci.9b00001

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    Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell
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      DOI: 10.1016/j.celrep.2021.109364

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  93. Mar 2021
  94. www.sciencedirect.com www.sciencedirect.com
    A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection
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  95. Feb 2021
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
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      DOI: 10.1021/acsptsci.9b00001

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  97. Jan 2021
  98. www.sciencedirect.com www.sciencedirect.com
    A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans
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      RRID:AB_1131294

      DOI: 10.1016/j.celrep.2020.108559

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  99. Nov 2020
  100. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TSPAN1: A Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance
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      Vinculin

      DOI: 10.3390/cancers12113269

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  101. Sep 2020
  102. www.sciencedirect.com www.sciencedirect.com
    Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses
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  103. www.sciencedirect.com www.sciencedirect.com
    Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module
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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of different L1 isoforms of Mastomys natalensis papillomavirus as mechanism to circumvent adaptive immunity
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      DOI: 10.7554/eLife.57626

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  105. www.jneurosci.org www.jneurosci.org
    Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development
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      anti-vinculin

      DOI: 10.1523/JNEUROSCI.1707-19.2020

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  106. Jan 2020
  107. www.sciencedirect.com www.sciencedirect.com
    A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas
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      RRID:AB_1131294

      DOI: 10.1016/j.devcel.2019.07.022

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  108. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      DOI: 10.1016/j.devcel.2019.04.014

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    Decreased Expression of Cilia Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Humans
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      RRID:AB_1131294

      DOI: 10.1016/j.celrep.2019.02.056

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  110. Nov 2017
  111. www.sciencedirect.com www.sciencedirect.com
    Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function
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