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Synaptophysin density underestimates synapse counts in the human brain – An anatomical study on synaptoporin protein expression

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1. scibot 25 Jun 2026
  
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  DOI: 10.1016/j.nbd.2026.107503
  
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sciencedirect.com/science/article/pii/S0969996126002482
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Synaptic alterations are preceding the axonal loss in optic atrophy of Wolfram syndrome mouse model

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1. scibot 13 Jun 2026
  
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  DOI: 10.3389/fnins.2026.1838257
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13236678/
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APOE is a presynaptic protein that accumulates with age and modulates neurotransmitter release

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1. scibot 06 Jun 2026
  
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  DOI: 10.64898/2026.04.20.719736
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13131475/
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A versatile nanobody platform for live and super-resolution imaging of synaptic vesicle dynamics and plasticity in rodent and human neurons

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1. scibot 21 May 2026
  
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  DOI: 10.1186/s12951-026-04489-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13185310/
Feb 2026
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Early life stress and disruption of the ageing trajectory in female rats: Insights into the origins and mechanisms underlying the risk of hypertension

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1. scibot 05 Feb 2026
  
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  DOI: 10.1113/EP093539
  
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physoc.onlinelibrary.wiley.com/doi/10.1113/EP093539
Dec 2025
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1-s2.0-S2589004225026768-main-html.html

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1. scibot 23 Dec 2025
  
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  DOI: 10.1016/j.isci.2025.114415
  
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54.241.53.176/ae86a4d7bd2bb12007a33d73a877aa48c665ccf6/1-s2.0-S2589004225026768-main-html.html
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Strikingly different neurotransmitter release strategies in dopaminergic subclasses

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1. scibot 18 Dec 2025
  
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  DOI: 10.7554/eLife.105271
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12707814/
Oct 2025
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Time-restricted feeding provides limited microglial immunometabolic improvements in diet-induced obese rats

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1. scibot 09 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116380
  
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sciencedirect.com/science/article/pii/S2211124725011519
Jul 2025
www.biorxiv.org www.biorxiv.org

Piccolo Regulates Secretion of the Extracellular Matrix Components Brevican and Tenascin R from Astrocytes to Drive Synapse Formation: Implications for Pontocerebellar Hypoplasia Type 3 (PCH3)

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1. scibot 08 Jul 2025
  
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  DOI: 10.1101/2025.07.03.662734
  
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biorxiv.org/content/10.1101/2025.07.03.662734v1
May 2025
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The Serine/Threonine Kinase NDR2 Regulates Integrin Signaling, Synapse Formation, and Synaptic Plasticity in the Hippocampus

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1. scibot 31 May 2025
  
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  DOI: 10.1111/jnc.70094
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12120816/
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Effect of Small Extracellular Vesicles Produced by Mesenchymal Stem Cells on 5xFAD Mice Hippocampal Cultures

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1. scibot 21 May 2025
  
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  DOI: 10.3390/ijms26094026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12071690/
Apr 2025
elifesciences.org elifesciences.org

Rab10 regulates neuropeptide release by maintaining Ca2+ homeostasis and protein synthesis

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1. scibot 03 Apr 2025
  
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  DOI: 10.7554/eLife.94930
  
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elifesciences.org/articles/94930
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CaV2.1 mediates presynaptic dysfunction induced by amyloid β oligomers

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1. scibot 01 Apr 2025
  
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  RRID:AB_1210382
  
  DOI: 10.1016/j.celrep.2025.115451
  
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sciencedirect.com/science/article/pii/S2211124725002220
Jan 2025
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Catecholaminergic dysfunction drives postural and locomotor deficits in a mouse model of spinal muscular atrophy

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1. scibot 07 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115147
  
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sciencedirect.com/science/article/pii/S2211124724014980
Dec 2024
52.53.155.43 52.53.155.43

Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport

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1. scibot 06 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.114357
  
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2. scibot 06 Dec 2024
  
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  RRID:AB_1210382
  
  DOI: 10.1016/j.celrep.2024.114357
  
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52.53.155.43/a5cd2a76f55670a4ac26cd7a0c2f7cbc81f1256c/Endoplasmic reticulum morphology regulation by RTN4 modulates neu-html.html
Sep 2024
www.cell.com www.cell.com

Divergent sensory pathways of sneezing and coughing

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.009
  
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cell.com/cell/fulltext/S0092-8674(24)00900-0
Jul 2024
52.53.155.43 52.53.155.43

Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport

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1. scibot 16 Jul 2024
  
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  RRID:AB_1210382
  
  DOI: 10.1016/j.celrep.2024.114357
  
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52.53.155.43/a5cd2a76f55670a4ac26cd7a0c2f7cbc81f1256c/Endoplasmic reticulum morphology regulation by RTN4 modulates neu-html.html
Apr 2024
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Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation in a GM1-gangliosidosis model

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1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114117
  
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sciencedirect.com/science/article/pii/S2211124724004455
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors

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1. scibot 27 Mar 2024
  
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  RRID:AB_1210382
  
  DOI: 10.1083/jcb.202307092
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10959120/
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Depletion of SMN protein in mesenchymal progenitors impairs the development of bone and neuromuscular junction in spinal muscular atrophy

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1. scibot 23 Mar 2024
  
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  DOI: 10.7554/eLife.92731
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10945524/
Feb 2024
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DLK signaling in axotomized neurons triggers complement activation and loss of upstream synapses

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113801
  
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sciencedirect.com/science/article/pii/S2211124724001293
Jan 2024
www.jneurosci.org www.jneurosci.org

Microglial Refinement of A-Fiber Projections in the Postnatal Spinal Cord Dorsal Horn Is Required for Normal Maturation of Dynamic Touch

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1. scibot 18 Jan 2024
  
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  DOI: 10.1523/JNEUROSCI.1354-23.2023
  
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jneurosci.org/content/44/2/e1354232023
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Synaptotagmin 9 Modulates Spontaneous Neurotransmitter Release in Striatal Neurons by Regulating Substance P Secretion

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1. scibot 18 Jan 2024
  
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  DOI: 10.1523/JNEUROSCI.1857-22.2023
  
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jneurosci.org/content/43/9/1475
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Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines

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1. scibot 18 Jan 2024
  
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  DOI: 10.1126/sciadv.ade1282
  
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science.org/doi/10.1126/sciadv.ade1282
Oct 2023
52.53.155.43 52.53.155.43

Tomosyns attenuate SNARE assembly and synaptic depression by binding to VAMP2-containing template complexes

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1. scibot 14 Oct 2023
  
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  RRID:AB_1210382
  
  DOI: 10.1101/2023.06.20.545669
  
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52.53.155.43/2bd44719e62866e4ff8df20b24d9e1fdce67593c/2023.06.20.545669.full-html.html
currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com

A Human Neuron/Astrocyte Co-culture to Model Seeded and Spontaneous Intraneuronal Tau Aggregation

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1. scibot 07 Oct 2023
  
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  DOI: 10.1002/cpz1.900
  
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currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.900
Aug 2023
rupress.org rupress.org

Presynapses contain distinct actin nanostructures

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1. scibot 29 Aug 2023
  
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  RRID:AB_1210382
  
  DOI: 10.1083/jcb.202208110
  
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rupress.org/jcb/article/222/10/e202208110/276185/Presynapses-contain-distinct-actin
Jul 2023
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Generation of mouse hippocampal brain organoids from primary embryonic neural stem cells

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1. scibot 22 Jul 2023
  
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  DOI: 10.1016/j.xpro.2023.102413
  
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sciencedirect.com/science/article/pii/S2666166723003805
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The kinesin Kif21b binds myosin Va and mediates changes in actin dynamics underlying homeostatic synaptic downscaling

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1. scibot 07 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112743
  
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sciencedirect.com/science/article/pii/S2211124723007544
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Morphology of Schwann Cell Processes Supports Renal Sympathetic Nerve Terminals With Local Distribution of Adrenoceptors

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1. scibot 04 Jul 2023
  
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  DOI: 10.1369/00221554221106812
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9284235/
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitofusin 2 sustains the axonal mitochondrial network to support presynaptic Ca2+ homeostasis and the synaptic vesicle cycle in rat hippocampal axons

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1. scibot 16 May 2023
  
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  DOI: 10.1523/JNEUROSCI.1356-22.2023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10175236/
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N-glycoproteomics of brain synapses and synaptic vesicles

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1. scibot 12 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112368
  
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sciencedirect.com/science/article/pii/S2211124723003790
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines

1
1. scibot 27 Apr 2023
  
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  AB_1210382
  
  DOI: 10.1126/sciadv.ade1282
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10115456/
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Synaptic vesicle proteins are selectively delivered to axons in mammalian neurons

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1. scibot 04 Feb 2023
  
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  RRID:AB_1210382
  
  DOI: 10.7554/eLife.82568
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9894587/
Jan 2023
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Intraneuronal tau aggregation induces the integrated stress response in astrocytes

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Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy

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Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones

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Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues

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SARS-CoV-2 infects neurons and induces neuroinflammation in a non-human primate model of COVID-19

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SMN controls neuromuscular junction integrity through U7 snRNP

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Melanopsin retinal ganglion cells mediate light-promoted brain development

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Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment

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Rebuilding essential active zone functions within a synapse

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Control of mammalian locomotion by ventral spinocerebellar tract neurons

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Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity

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Silencing long ascending propriospinal neurons after spinal cord injury improves hindlimb stepping in the adult rat

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Central synaptopathy is the most conserved feature of motor circuit pathology across spinal muscular atrophy mouse models

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Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells

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Morphological assessment of GABA and glutamate inputs to GnRH neurons in intact female mice using expansion microscopy

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Surface charge manipulation and electrostatic immobilization of synaptosomes for super-resolution imaging: a study on tau compartmentalization

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Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons

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Untitled document

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Jul 2021
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cindr, the Drosophila Homolog of the CD2AP Alzheimer’s Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis

1
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  guinea pig anti-Synaptophysin
  
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Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies

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Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity

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Relaxin-3 Innervation From the Nucleus Incertus to the Parahippocampal Cortex of the Rat

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Glycinergic axonal inhibition subserves acute spatial sensitivity to sudden increases in sound intensity

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Sneezing reflex is mediated by a peptidergic pathway from nose to brainstem

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PKC-phosphorylation of Liprin-α3 triggers phase separation and controls presynaptic active zone structure

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May 2021
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Aberrant axo-axonic synaptic reorganization in the phosphorylated L1-CAM/calcium channel subunit alpha2 delta-1-containing central terminals of injured c-fibers in the spinal cord of a neuropathic pain model

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Mar 2021
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Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR

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Presynaptic activity and protein turnover are correlated at the single-synapse level

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Feb 2021
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Rho‐Kinase Inhibition by Fasudil Modulates Presynaptic Vesicle Dynamics

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Highly redundant neuropeptide volume co-transmission underlying episodic activation of the GnRH neuron dendron

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Nov 2020
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Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry

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Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and Immunosuppression

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Oct 2020
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Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain

1
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Sep 2020
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Prelimbic cortical targets of ventromedial thalamic projections include inhibitory interneurons and corticostriatal pyramidal neurons in the rat

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Acute disruption of the synaptic vesicle membrane protein synaptotagmin 1 using knockoff in mouse hippocampal neurons

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  DOI: 10.7554/eLife.56469
  
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CtBP1-Mediated Membrane Fission Contributes to Effective Recycling of Synaptic Vesicles

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Microglia Regulate Pruning of Specialized Synapses in the Auditory Brainstem

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AMPAR Auxiliary Protein SHISA6 Facilitates Purkinje Cell Synaptic Excitability and Procedural Memory Formation

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Different dendritic domains of the GnRH neuron underlie the pulse and surge modes of GnRH secretion in female mice

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  DOI: 10.7554/eLife.53945
  
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The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice

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Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder

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A Comprehensive Structure-Function Study of Neurogenin3 Disease-Causing Alleles during Human Pancreas and Intestinal Organoid Development

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  DOI: 10.1016/j.devcel.2019.05.017
  
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Arterial Baroreceptors Sense Blood Pressure through Decorated Aortic Claws

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Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy

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SALM1 controls synapse development by promoting F‐actin/PIP2‐dependent Neurexin clustering

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  DOI: 10.15252/embj.2018101289
  
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embopress.org/doi/full/10.15252/embj.2018101289
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The Classical Complement Pathway Mediates Microglia-Dependent Remodeling of Spinal Motor Circuits during Development and in SMA

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The RAB3-RIM Pathway Is Essential for the Release of Neuromodulators

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  DOI: 10.1016/j.neuron.2019.09.015
  
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Untitled document

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  DOI: 10.1016/j.neuron.2019.01.001
  
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Untitled document

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  DOI: 10.1016/j.neuron.2019.01.014
  
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Untitled document

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  DOI: 10.1016/j.celrep.2019.04.058
  
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Nov 2018
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The Presynaptic Protein Mover Is Differentially Expressed Across Brain Areas and Synapse Types

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RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes

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Rbfox1 Regulates Synaptic Transmission through the Inhibitory Neuron-Specific vSNARE Vamp1

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Dense‐Core Vesicle biogenesis and exocytosis in neurons lacking Chromogranins A and B

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onlinelibrary.wiley.com/doi/10.1111/jnc.14263/full
Nov 2017
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Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking

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Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons

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1. scibot 08 Nov 2017
  
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Structured Dendritic Inhibition Supports Branch-Selective Integration in CA1 Pyramidal Cells

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