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HEB collaborates with TCR signaling to upregulate Id3 and enable γδT17 cell maturation in the fetal thymus

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1. scibot 25 Apr 2026
  
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  DOI: 10.7554/eLife.109197
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13102393/
Apr 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004226010990-main-html.html

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1. scibot 15 Apr 2026
  
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  DOI: 10.1016/j.isci.2026.115724
  
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54.241.53.176/3e4dd64cfd78cb2c721fb48c4f44096804ced4e8/1-s2.0-S2589004226010990-main-html.html
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Distinct tissue niches contribute to prostate tissue-resident memory CD8+ T cell differentiation and heterogeneity

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1. scibot 02 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.03.003
  
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sciencedirect.com/science/article/pii/S1074761326001147
Mar 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004226008801-main-html.html

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.isci.2026.115505
  
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54.241.53.176/fe113be5e0479b752456981d23467ff50eff5555/1-s2.0-S2589004226008801-main-html.html
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Myofibroblast programming blocks differentiation of TLS-organizing fibroblastic reticular cells in pancreatic cancer

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.ccell.2026.03.004
  
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sciencedirect.com/science/article/pii/S153561082600156X
Feb 2026
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B lymphocytes that enter the germinal center late preferentially differentiate into memory cells that recognize subdominant epitopes

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1. scibot 27 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.027
  
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sciencedirect.com/science/article/pii/S1074761326000488
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Local antibody feedback enforces a checkpoint on affinity maturation in the germinal center and promotes epitope spreading

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.011
  
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sciencedirect.com/science/article/pii/S1074761326000324
Jan 2026
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MyD88 signaling in myeloid cells induces gastrointestinal tract injury and systemic inflammation after West Nile virus infection

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1. scibot 22 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116852
  
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sciencedirect.com/science/article/pii/S2211124725016249
Nov 2025
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Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8+ T cell immunity against melanoma

1
1. scibot 05 Nov 2025
  
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  DOI: 10.1016/j.immuni.2025.10.004
  
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sciencedirect.com/science/article/pii/S1074761325004340
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Optimal CXCR5 expression during Tfh maturation involves the Bhlhe40-Pou2af1 axis

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1. scibot 23 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116470
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12744931/
Aug 2025
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Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control

1
1. scibot 06 Aug 2025
  
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  DOI: 10.1016/j.cmet.2025.07.006
  
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sciencedirect.com/science/article/pii/S155041312500333X
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PIM kinase control of CD8 T cell protein synthesis and cell trafficking

1
1. scibot 22 May 2025
  
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  RRID:AB_1272185
  
  DOI: 10.7554/eLife.98622
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12074636/
Apr 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225007497-main-html.html

1
1. scibot 24 Apr 2025
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.isci.2025.112488
  
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52.53.155.43/dc000beb0032bb6d75063610e91edb7d9a897a11/1-s2.0-S2589004225007497-main-html.html
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An erythroid-biased FOShi hematopoietic multipotent progenitor subpopulation contributes to adaptation to chronic hypoxia

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.stem.2025.03.010
  
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sciencedirect.com/science/article/pii/S1934590925001006
Mar 2025
www.cell.com www.cell.com

Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity

1
1. scibot 24 Mar 2025
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.xcrm.2025.102035
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00108-9
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Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs

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1. scibot 20 Mar 2025
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.cell.2025.02.014
  
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sciencedirect.com/science/article/pii/S0092867425001990
Feb 2025
aacrjournals.org aacrjournals.org

Interferon-a potentiates anti-PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment

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1. scibot 14 Feb 2025
  
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  RRID:AB_1272185
  
  DOI: 10.1158/2159-8290.CD-21-1022
  
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aacrjournals.org/cancerdiscovery/article/12/7/1718/705192/IFN-Potentiates-Anti-PD-1-Efficacy-by-Remodeling
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Inositol polyphosphate multikinase regulates Th1 and Th17 cell differentiation by controlling Akt-mTOR signaling

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1. scibot 13 Feb 2025
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.celrep.2025.115281
  
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sciencedirect.com/science/article/pii/S221112472500052X
Jan 2025
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Antigen affinity and site of immunization dictate B cell recall responses

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1. scibot 16 Jan 2025
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.celrep.2024.115221
  
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sciencedirect.com/science/article/pii/S2211124724015729
Nov 2024
pubs.acs.org pubs.acs.org

Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting β-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells

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1. scibot 29 Nov 2024
  
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  DOI: 10.1021/acs.jmedchem.3c02079
  
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pubs.acs.org/doi/10.1021/acs.jmedchem.3c02079
Aug 2024
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LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity

1
1. scibot 20 Aug 2024
  
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  AB_1272185
  
  DOI: 10.1016/j.cell.2024.07.018
  
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sciencedirect.com/science/article/pii/S0092867424007785
pubs.acs.org pubs.acs.org

Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting β-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells

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1. scibot 02 Aug 2024
  
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  DOI: 10.1021/acs.jmedchem.3c02079
  
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pubs.acs.org/doi/10.1021/acs.jmedchem.3c02079
Jul 2024
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Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function

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1. scibot 25 Jul 2024
  
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  AB_1272185
  
  DOI: 10.1016/j.celrep.2024.114506
  
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sciencedirect.com/science/article/pii/S2211124724008350
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Brain intratumoural astatine-211 radiotherapy targeting syndecan-1 leads to durable glioblastoma remission and immune memory in female mice

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1. scibot 17 Jul 2024
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.ebiom.2024.105202
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11246004/
Jun 2024
www.cell.com www.cell.com

The alarmin IL-33 exacerbates pulmonary inflammation and immune dysfunction in SARS-CoV-2 infection

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1. scibot 30 Jun 2024
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.isci.2024.110117
  
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cell.com/iscience/abstract/S2589-0042(24)01342-7
Apr 2024
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Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy

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1. scibot 24 Apr 2024
  
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  AB_1272185
  
  DOI: 10.1016/j.celrep.2024.114141
  
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sciencedirect.com/science/article/pii/S2211124724004698
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PUS1 regulates erythropoiesis via tRNA pseudouridylation and cytoplasmic translation

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1. scibot 09 Mar 2024
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.isci.2024.109265
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10915626/
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Differentiation route determines the functional outputs of adult megakaryopoiesis

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1. scibot 06 Mar 2024
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.immuni.2024.02.006
  
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sciencedirect.com/science/article/pii/S1074761324000827
Aug 2023
52.53.155.43 52.53.155.43

Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis

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1. scibot 16 Aug 2023
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.isci.2023.107626
  
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52.53.155.43/7577b316449823f049fb40596d10129f31e9ac4b/PIIS2589004223017030-html.html
Jun 2023
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Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression

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1. scibot 08 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112599
  
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sciencedirect.com/science/article/pii/S2211124723006101
Mar 2023
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B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection

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1. scibot 11 Mar 2023
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.immuni.2023.02.003
  
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sciencedirect.com/science/article/pii/S1074761323000778
Feb 2023
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DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell development

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1. scibot 17 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112106
  
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sciencedirect.com/science/article/pii/S2211124723001171
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Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria

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1. scibot 03 Feb 2023
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.cell.2022.12.038
  
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sciencedirect.com/science/article/pii/S0092867422015811
Jan 2023
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Continuous germinal center invasion contributes to the diversity of the immune response

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1. scibot 28 Jan 2023
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.cell.2022.11.032
  
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Design, synthesis and biological evaluation of quercetin derivatives as novel β-catenin/B-cell lymphoma 9 protein−protein interaction inhibitors

1
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A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice

1
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  DOI: 10.7554/eLife.81453
  
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Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment

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  DOI: 10.1016/j.cell.2022.10.006
  
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Tumor-infiltrated activated B cells suppress liver metastasis of colorectal cancers

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Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus

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Jun 2022
52.53.155.43 52.53.155.43

cd-21-1022-html.html

3
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  DOI: 10.1158/2159-8290.CD-21-1022
  
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  DOI: 10.1158/2159-8290.cd-21-1022
  
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Maternal-fetal conflict averted by progesterone- induced FOXP3+ regulatory T cells

1
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  DOI: 10.1016/j.isci.2022.104400
  
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Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells

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YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation

1
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Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation

1
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  DOI: 10.1016/j.ccell.2021.10.008
  
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Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis

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Oct 2021
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PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory

1
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  DOI: 10.1016/j.celrep.2021.109804
  
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Sep 2021
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Brief homogeneous TCR signals instruct common iNKT progenitors whose effector diversification is characterized by subsequent cytokine signaling

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  DOI: 10.1016/j.immuni.2021.09.003
  
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PD-1+ Tcf1+ CD8+ T cells from established chronic infection can form memory while retaining a stableimprint of persistent antigen exposure

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  DOI: 10.1016/j.celrep.2021.109672
  
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Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells

1
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  DOI: 10.1016/j.immuni.2018.01.013
  
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A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment

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  DOI: 10.7554/eLife.37851
  
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Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function

1
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  DOI: 10.1016/j.immuni.2018.09.014
  
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Jul 2021
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Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

1
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  CD8a Monoclonal Antibody, APC-eFluor 780
  
  DOI: 10.1016/j.molcel.2019.08.005
  
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Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells

1
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  DOI: 10.1016/j.immuni.2018.01.013
  
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Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice

1
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  DOI: 10.1016/j.cell.2016.07.030
  
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An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αβ T Cell Development

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Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation

1
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  DOI: 10.1016/j.immuni.2020.09.005
  
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The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation

1
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Mar 2021
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Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells

1
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  Anti-mouse CD8-eF780 (53-6.7)
  
  DOI: 10.1016/j.xpro.2021.100389
  
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Feb 2021
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Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates

1
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  DOI: 10.1016/j.cell.2020.09.063
  
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CD103+ cDC1 and endogenous CD8+ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function

1
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  DOI: 10.1038/s41467-020-19833-3
  
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Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy

1
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  DOI: 10.1016/j.immuni.2020.04.007
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7784612/
Dec 2020
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Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates

1
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  RRID: AB_1272185
  
  DOI: 10.1016/j.cell.2020.09.063
  
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cell.com/cell/abstract/S0092-8674(20)31304-0
Sep 2020
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Protein Kinase A Catalytic Subunit Is a Molecular Switch that Promotes the Pro-tumoral Function of Macrophages

1
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  DOI: 10.1016/j.celrep.2020.107643
  
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B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer’s Patches

1
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  DOI: 10.1016/j.celrep.2020.01.032
  
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C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor

1
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CD8+ T Cell Functional Exhaustion Overrides Pregnancy-Induced Fetal Antigen Alloimmunization

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  DOI: 10.1016/j.celrep.2020.107784
  
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MicroRNA-9 Fine-Tunes Dendritic Cell Function by Suppressing Negative Regulators in a Cell-Type-Specific Manner

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  DOI: 10.1016/j.celrep.2020.107585
  
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sciencedirect.com/science/article/pii/S2211124720305349
Jan 2020
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γδ-T cells promote IFN-γ–dependent Plasmodium pathogenesis upon liver-stage infection

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1. scibot 13 Jan 2020
  
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  RRID:AB_1272185
  
  DOI: 10.1073/pnas.1814440116
  
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  Curator: @evieth
  
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Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus

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1. scibot 13 Jan 2020
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.immuni.2019.09.001
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1074761319303723
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Protein Amounts of the MYC Transcription Factor Determine Germinal Center B Cell Division Capacity

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1. scibot 13 Jan 2020
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.immuni.2019.06.013
  
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Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population

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1. scibot 13 Jan 2020
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.celrep.2019.11.042
  
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Quantitative Difference in PLZF Protein Expression Determines iNKT Lineage Fate and Controls Innate CD8 T Cell Generation

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1. scibot 13 Jan 2020
  
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  RRID:AB_1272185
  
  DOI: 10.1016/j.celrep.2019.05.012
  
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sciencedirect.com/science/article/pii/S2211124719306230
Nov 2018
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LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance

1
1. scibot 05 Nov 2018
  
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  RRID:AB_1272185
  
  Curator: @Jmenke
  
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Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia

1
1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6097876/
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Untitled document

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1535610818303131
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Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors

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1. scibot 05 Nov 2018
  
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Co-inhibitory Molecule B7 Superfamily Member 1 Expressed by Tumor-Infiltrating Myeloid Cells Induces Dysfunction of Anti-tumor CD8+ T Cells

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1. scibot 05 Nov 2018
  
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  RRID:AB_1272185
  
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sciencedirect.com/science/article/pii/S1074761318301158
Nov 2017
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Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis

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1. scibot 08 Nov 2017
  
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  AB_1272185
  
  Curator: @chewbeccax
  
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sciencedirect.com/science/article/pii/S1931312817302056

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