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Single cell CRISPR screen identifies antagonism between Nsd1-H3K36me2 and Ezh2-H3K27me3 orchestrates pluripotency transition

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1. scibot 18 Jul 2026
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.stemcr.2026.103016
  
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sciencedirect.com/science/article/pii/S2213671126002274
Jul 2026
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Thyroid cancer-associated EZH1 Q571R mutation drives chromatin compaction and H3K27me3 invasion into active chromatin

1
1. scibot 07 Jul 2026
  
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  DOI: 10.1016/j.molcel.2026.06.021
  
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sciencedirect.com/science/article/pii/S1097276526004107
Apr 2026
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mct-25-0268-html.html

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1. scibot 12 Apr 2026
  
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  RRID:AB_1281338
  
  DOI: 10.1158/1535-7163.MCT-25-0268
  
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54.241.53.176/a412b4ecb928f944e0b118b139f1e81bba8c2102/mct-25-0268-html.html
Jun 2025
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Bivalent chromatin instructs lineage specification during hematopoiesis

1
1. scibot 18 Jun 2025
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.cell.2025.05.011
  
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sciencedirect.com/science/article/pii/S0092867425005616
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors

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1. scibot 13 Feb 2025
  
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  RRID:AB_1281338
  
  DOI: 10.1083/jcb.202308064
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11318668/
Oct 2024
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Multiplexed chromatin immunoprecipitation sequencing for quantitative study of histone modifications and chromatin factors

1
1. scibot 08 Oct 2024
  
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  RRID:AB_1281338
  
  DOI: 10.1038/s41596-024-01058-z
  
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link.springer.com/article/10.1038/s41596-024-01058-z
Sep 2024
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Activation of automethylated PRC2 by dimerization on chromatin

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.molcel.2024.08.025
  
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sciencedirect.com/science/article/pii/S1097276524007020
Mar 2024
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MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors

2
1. scibot 07 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109188
  
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2. scibot 06 Mar 2024
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.isci.2024.109188
  
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sciencedirect.com/science/article/pii/S2589004224004097
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Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice

2
1. scibot 06 Mar 2024
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.celrep.2024.113875
  
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2. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113875
  
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sciencedirect.com/science/article/pii/S2211124724002031
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Alternative splicing decouples local from global PRC2 activity

2
1. scibot 06 Mar 2024
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.molcel.2024.02.011
  
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2. scibot 06 Mar 2024
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.molcel.2024.02.011
  
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sciencedirect.com/science/article/pii/S1097276524001308
Sep 2023
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Discordant interactions between YAP1 and polycomb group protein SCML2 determine cell fate

1
1. scibot 30 Sep 2023
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.isci.2023.107964
  
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sciencedirect.com/science/article/pii/S2589004223020412
Jun 2023
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Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity

1
1. scibot 02 Jun 2023
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.ccell.2023.05.005
  
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sciencedirect.com/science/article/pii/S1535610823001733
Jan 2023
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Remarkable Synergy When Combining EZH2 Inhibitors with YM155 Is H3K27me3-Independent

1
1. scibot 04 Jan 2023
  
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  RRID:AB_1281338
  
  DOI: 10.3390/cancers15010208
  
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mdpi.com/2072-6694/15/1/208
Mar 2022
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The KRAS-G12D mutation induces Metabolic Vulnerability in B-cell Acute Lymphoblastic Leukemia

1
1. scibot 02 Mar 2022
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.isci.2022.103881
  
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sciencedirect.com/science/article/pii/S2589004222001511
Nov 2021
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Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks

1
1. scibot 10 Nov 2021
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.molcel.2021.10.008
  
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sciencedirect.com/science/article/pii/S1097276521008376
Sep 2021
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NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis

1
1. scibot 23 Sep 2021
  
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  9728S
  
  DOI: 10.1016/j.molcel.2021.08.034
  
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sciencedirect.com/science/article/pii/S1097276521007140
Apr 2021
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SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways

1
1. scibot 17 Apr 2021
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.ccell.2020.05.022
  
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  RRID:AB_1281338 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610820302725
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SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy

1
1. scibot 17 Apr 2021
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.ccell.2020.04.014
  
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sciencedirect.com/science/article/pii/S1535610820302130
Feb 2021
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Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants

1
1. scibot 25 Feb 2021
  
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  AB_1281338
  
  DOI: 10.1016/j.stem.2021.01.016
  
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sciencedirect.com/science/article/pii/S1934590921000163
Nov 2020
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H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation

1
1. scibot 25 Nov 2020
  
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  DOI: 10.1016/j.celrep.2020.108390
  
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sciencedirect.com/science/article/pii/S2211124720313796
Sep 2020
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Domain Model Explains Propagation Dynamics and Stability of Histone H3K27 and H3K36 Methylation Landscapes

1
1. scibot 16 Sep 2020
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.celrep.2019.12.060
  
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sciencedirect.com/science/article/pii/S2211124719317176
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Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis

1
1. scibot 12 Sep 2020
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.celrep.2020.107990
  
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sciencedirect.com/science/article/pii/S221112472030975X
Jan 2020
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Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.molcel.2019.11.021
  
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sciencedirect.com/science/article/pii/S1097276519308901
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Quantitative Multiplexed ChIP Reveals Global Alterations that Shape Promoter Bivalency in Ground State Embryonic Stem Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.celrep.2019.08.046
  
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sciencedirect.com/science/article/pii/S2211124719310940
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PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1281338
  
  DOI: 10.1016/j.molcel.2019.08.012
  
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sciencedirect.com/science/article/pii/S1097276519306288
Nov 2018
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Capturing the Onset of PRC2-Mediated Repressive Domain Formation

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276518303976
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Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2

1
1. scibot 05 Nov 2018
  
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  9728
  
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sciencedirect.com/science/article/pii/S1097276518302223
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Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276518302235
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The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276518301722
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Early-Life Gene Expression in Neurons Modulates Lasting Epigenetic States

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0092867417311418