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The molecular mechanism of melatonin in regulating osteoporosis based on the RANKL/OPG signaling axis

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Impact of O-GlcNAcylation elevation on mitophagy and glia in the dentate gyrus

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Pro-repair properties of a human embryonic stem cell-derived astrocyte cell therapy in demyelinating disorders

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Suppression of ATM kinase signaling accelerates cellular senescence

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Electron transport chain complex I and mitochondrial fusion regulate ROS for differentiation in Drosophila neural stem cells

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Chemical Modulation of Miro1 Alleviates Cell-Type-Specific Vulnerabilities in Friedreich’s Ataxia

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STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation

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Spermidine suppresses glial inflammation and parkinsonian abnormalities in ATP13A2 deficiency

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Chemogenetic activation of the amygdala core nucleus increases aggression in chickens

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Long-term reversal of Duchenne muscular dystrophy via circular arRNA-guided exon skipping in monkeys and humans

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Methamphetamine potentiates the use of outcome-specific associations via a hypothalamic-dopamine circuit

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Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of aged APP knock-in mice

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Epithelial cell expansion drives cyst progression in genetic models of autosomal recessive polycystic kidney disease

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The modulation of AUF1 regulates the R-loop resolution activating the immune response in DDR

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Spatial and temporal single cell multi-omics in mice reveals macrophage-SFRP4+ stroma interactions promoting endometrial regeneration via TNF-α

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Deep learning of functional perturbations from condensate morphology

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2026.05.25.727656.full-html.html

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The heat shock transcription factor, HSF1, stimulates the catalytic engagement of topoisomerase IIβ over topoisomerase IIα

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Rosavin mitigates hepatic fibrosis via KLF14-mediated suppression of P2X7 receptor-dependent inflammatory signaling cascades

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Novel Mechanism of and Therapeutic Approach for Anthracycline-Induced Cardiotoxicity

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Motor-to-Limbic Design of Direct Synaptic Communication between Dopamine Neurons in the Midbrain

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Enhanced formaldehyde clearance ameliorates differentiation-induced genotoxicity in Fanconi anemia mutant cells

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RNA-binding protein diversity and NLS arginines regulate FUS mixing in mRNA-rich compartments

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Non-centromeric CENP-A regulates epithelial-mesenchymal plasticity and heterogeneity in human cells

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The Neuroanatomy of the Hawaiian Bobtail Squid Juvenile Bacterial Light Organ

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Assessment of Cell-Type-Specific Excitatory Synaptic Strength in the Dorsolateral Striatum of Goal-Directed and Habitual Cocaine-Seeking Behavior

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Melatonin alleviates neuroinflammation in ischemic stroke by regulating cyclic GMP-AMP synthase– mediated microglial pyroptosis signaling

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Lipidomic and sterolomic profiles of different brain regions in the mouse model of Alzheimer’s disease

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Breaking Barriers: Proof of Concept for Selective Coronary Endothelial Decellularization in Whole Porcine Hearts for Xenotransplantation

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Human retinal organoids functionally bridge a transected optic nerve in a rat model

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A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth

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Protocol for cell cycle-resolved high-content imaging of transcription condensate dynamics in human cells

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  DOI: 10.1016/j.xpro.2026.104589
  
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Alphaviral non-structural protein-host RBP co-condensation as a mechanism to sustain virus replication

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Global transcriptional changes across multiple isogenic C9orf72 patient iPSC-derived neurons

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RpS12-mediated induction of the Xrp1short isoform links ribosomal protein mutations to cell competition

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TLR4-paxillin-Rac1 signaling mediates LPS-induced dysregulation of keratinocyte function

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A versatile nanobody platform for live and super-resolution imaging of synaptic vesicle dynamics and plasticity in rodent and human neurons

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Slow-wave sleep engages brainstem circuitry to prevent stress-induced anxiety

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Wake-active brainstem GABA neurons signal sleep pressure by upregulating AMPA receptors to drive recovery sleep

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Adhesion-controlled mechanics of the glial niche regulate neural stem cell proliferative potential

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Vitamin B12 ameliorates gut epithelial injury via modulating the HIF-1 pathway and gut microbiota

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Generation of hiPSCs (JUCGRMi008-A) from a β-propeller protein-associated neurodegeneration patient with WDR45 mutation

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S-acylation of TDP43 regulates its condensation in amyotrophic lateral sclerosis

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Connexin Regulation and Modulation of Neural Stem Cell Differentiation Induced by Cell-Permeable Itaconate

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  DOI: 10.1002/jcp.70185
  
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Ferroptosis inhibition enhances liver and lung graft function

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Hugin-AstA circuitry is a novel central energy sensor that directly regulates sweet sensation in Drosophila and mouse

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Regulation of AP1 adaptor assembly by the bi-handed chaperone MEA1

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Olfactomedin4 marks luminal progenitor cells that give rise to secretory cell lineage in the mouse cervix

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Hepatic expression of APOE3 Christchurch mitigates APOE4-related Alzheimer’s disease pathologies in mice

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CLDN6 Expression Plasticity in Ovarian Cancer: Insights into Therapeutic Optimization for CLDN6-Targeted Immunotherapy

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GPR180 deficiency impairs mitochondrial function and insulin secretion in pancreatic β-cells

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It’s Not Rewarding for Mitochondria: Dopamine-Induced Mitochondrial Dysfunction Activates cGAS-STING to Drive IL-6 Secretion in Macrophages

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The circadian gene Dec2 promotes pancreatic cancer progression and dormancy through immune evasion

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Cerebellar acceleration of learning in an evidence-accumulation task

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Tissue tension fosters macrophage-driven lipid peroxidation-induced DNA damage

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A supracellular actin network transmits forces over long distances at the apical surface of squamous carcinoma cells

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BPS Publications

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  DOI: 10.1111/bph.70440
  
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Acyltransferase ZDHHC22 promotes N-Myc transcriptional activation to drive neuroblastoma progression and chemoresistance

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Ubiquilin1 restricts influenza viral replication through trapping vRNP in the late endosomes

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Gastric epithelium from BRCA1 and BRCA2 carriers harbors increased double-stranded DNA damage and enhanced growth potential

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TRIP8bnano peptide prevents cAMP binding to HCN2 channels alleviating pain-like behaviors in rats with neuropathic pain

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Clathrin-independent endocytosis and retrograde transport in cancer cells tune immune synapse organization and CD8 T cell response

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Resilience to Cardiac Aging in Greenland Shark Somniosus microcephalus

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Functional signatures of de novo GABBR1 and GABBR2 variants associated with neurodevelopmental disorders

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Broad Glucagon-Like Peptide-1 (GLP-1) Receptor Distribution Enhances Glutamatergic Transmission Throughout the Mouse Cerebellar Cortex.

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A skeletal muscle atlas shows neuromuscular junction adaptations to growth and atrophy

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Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin

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Redox regulation of neuroinflammatory pathways contributes to damage in Alzheimer’s disease brain

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Supplementary file-html.html

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PHF2 regulates grip strength via demethylation at the promoter region of the Mef2c

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Interaction of Plasmodium yoelii tryptophan-rich antigen 7 with CD71 on macrophage membrane regulates host inflammatory response

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Physiological Respiration Pressure-Driven Piezocatalytic Therapy for Malignant Ascites with a Gold-Core Magnified Mesoporous Piezoelectric Nanoplatform

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  DOI: 10.1016/j.biomaterials.2026.124233
  
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RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal Metastasis

1
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Peptide-Mediated Delivery of α-Synuclein Targeting ASO: Pharmacokinetics, Safety, and CNS Efficacy in a Synucleinopathy Model

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Noninvasive Focal Gene Delivery into the Cerebellum of Non-Human Primates using Focused Ultrasound

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The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

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Dopamine neuron specific RNA-sequencing reveals Neprilysin 1 acts downstream of the cohesin complex to suppress learning

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Disease-causing mutations in Synaptotagmin can act via dominant-negative, gain-of-function or haploinsufficient mechanisms

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Cadherin-engineered microspheres enable scalable biofabrication of multilineage liver organoids

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1-s2.0-S2589004226011119-main-html.html

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hwang-cho-2026-primary-cilia-mediate-stress-vulnerability-and-exercise-induced-antidepressant-adaptation-evidence-for-html.html

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Electromagnetic field-inducible in vivo gene switch for remote spatiotemporal control of gene expression

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The Role of Disulfide Bonds in the GluN1 Subunit in the Early Trafficking and Functional Properties of GluN1/GluN2 and GluN1/GluN3 NMDA Receptors

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Rac1 Constrains Memory Consolidation

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1-s2.0-S2589004226010862-main-html.html

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Asymmetric Lateral Habenula Function and Peripheral Neural Mechanisms in Regulating Itch-Evoked Scratching

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Acute requirement for the hippocampus in putatively conscious vision revealed by a mouse model of blindsight

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A novel conserved protein associates with the IFT-A complex to mediate nuclear translocation of β-catenin in Wg/Wnt-signaling

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Yellow Fever Virus Interactomes Reveal Common and Divergent Strategies of Replication and Evolution for Mosquito-borne Flaviviruses

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Three donor-matched iPSC lines derived from human postmortem dura mater for modeling neurodegenerative diseases

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Generation of three hiPSC clones from a frontotemporal dementia (FTD) patient with a heterozygous MAPT mutation p.K298_H299insQ (c.896_897insACA)

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1-s2.0-S2589004226010151-main-html.html

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Nonsense-mediated mRNA decay inhibition reshapes the cancer immunopeptidome

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TUB-040, a Homogeneous and Hydrophilic NaPi2b-Targeting ADC with Stably Linked Exatecan, Exhibits Long-lasting Antitumor Activity and a Well-Tolerated Safety Profile

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Development of multivalent FAP-targeted Small Molecule-Drug Conjugates with tailored MMAE release kinetics

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Harnessing senolytics and PARP inhibition to expand the antitumor activity of CDK4/6 inhibitors in prostate cancer

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Wg/Wnt-signaling-induced nuclear translocation of β-catenin is attenuated by a β-catenin peptide through its interference with the IFT-A complex

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Human promoter-driven AAV tools enable precision gene therapy targeting cochlear hair cells

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Clinical-scale bioreactor production of hiPSC-derived extracellular vesicles modulates miRNA and protein cargo to enhance angiogenic function

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TMEM145 is a principal component of outer hair cell stereocilia

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Unveiling the molecular architecture of T cells and immune synapses with cryo-expansion microscopy

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A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive-Free, Topography-Driven Osteogenesis

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advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202504865
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Cocaine-Induced Immediate-Early Gene Expression in the Nucleus Accumbens: Roles of Separate cAMP Sensors

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Metabolic stress sensing by epithelial RXRα links westernization of diet with Crohn’s disease

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Mar 2026
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Synthetic M13 phage engagers expand CAR-T cell antigen recognition to overcome tumor heterogeneity

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A septal inhibitory circuit constrains alcohol reward and mediates liraglutide’s suppressive effects on alcohol intake in mice

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  DOI: 10.1016/j.neuron.2026.02.019
  
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Neurovascular large artery dilatation increases the risk for Alzheimer's disease pathology

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Electrophysiological development and functional plasticity in dissociated human cerebral organoids across multiple cell lines

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A genetic strategy for targeting local astrocytes in adult Drosophila

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Innate Immune Receptor NLRX1: Potential Modulator of Glioblastoma Pathophysiology

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Sequential formation of Drosophila circuit asymmetry via prolonged structural plasticity

1
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Microglia-mediated protection against Alzheimer’s disease pathology and detrimental effects in white matter revealed by Ptpn6 deletion

1
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p16High-expressing immune cells control disease tolerance as a defense and health span-extending strategy

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Non-gonadal PIWIL1/Aubergine drives regenerative and tumorigenic stem cell proliferation and tumorigenesis in the intestine

1
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JAK/STAT1-interferon-ISGylation networks in breast cancer resistance to inhibitors of FOXM1 and CDK4/6

1
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CAR-M2 immunotherapy resolves renal fibrosis via revascularization and apoptosis of profibrotic Cxcr2+ endothelial cells

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The nBAF complex subunit CREST/SS18L1 regulates hippocampal memory processes via tyrosine 397 and histone acetyltransferase CBP

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STING signaling modulation by COPII cargo recognition

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Brain-gonad axes harmonize male mating drive and reproductive strategy via steroid hormones

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Polθ activity modulates sensitivity to standard therapies in DNMT3A-deficient leukemia

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ER-tethering directs TREX1 penetration of a BAF-dependent barrier at micronuclei

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Young Regulatory T Cell-Derived Extracellular Vesicles Improve Mitochondrial Function and Angiogenesis and Suppress Inflammation in Senescent Brain and Heart

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Overexpression of the ERG oncogene in prostate cancer identifies candidates for PARP inhibitor-based radiosensitization

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IL-9 promotes migratory dissemination of malignant T-cells by activating the HIF-1α-Cofilin-1 axis in cutaneous T-cell lymphoma

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Chimeric brain models to study human glial-neuronal and macroglial-microglial interactions

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Radiation-induced autophagy regulates fibroblast mitochondrial metabolism and crosstalk with triple-negative breast cancer cells

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Loss of p53 exacerbates autoimmunity by reprogramming propionyl-CoA metabolism and histone modifications in Treg cells

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Microbiome-produced nicotinic acid controls colon regional identity and injury susceptibility

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Abrogation of presynaptic facilitation at hippocampal mossy fiber synapses disrupts neural ensemble activity and spatial memory

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CBP-IDRs regulate acetylation and gene expression

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Generation of a human induced pluripotent stem cell line (FLENIi004-A) from an Autosomal-Dominant Alzheimer’s disease PSEN1 p.M146L patient

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HIF-1α+ CD4+ T cells coordinate a tissue-resident immune cell network in the lung

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NAD+ hydrolysis catalyzed by SelO is required for mitochondrial homeostasis

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MYH9 mutations differentially stabilize non-muscle myosin II filaments and induce distinct cellular aggregation phenotypes

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1-s2.0-S2589004226006176-main-html.html

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Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

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SSRN-id4461873-html.html

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ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

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2026.02.24.707778.full-html.html

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Reconstruction of T cell infiltration in an osteosarcoma PDX-organoid interactive biobank for personalized immunotherapy

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A pair of interneurons that confer positive real-time valence to sweet sensation in Drosophila

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MafB is a conserved transcriptional regulator of macrophage development and functional identity across tissues and species

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Inhibitory circuits control leg movements during Drosophila grooming

1
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Morphological innovation without gene co-option: the Drosophila sex comb evolved via changes in developmental tempo and energy metabolism

1
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Ethanol Alters DNMT1/3a/3b Expression Profile, Promotes Persistent DNA Hypomethylation in Human Brain Endothelial Cells and Impairs Late Cortical Angiogenesis

2
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MEDAG functions as an A-kinase-anchoring protein in adipocytes

1
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54.241.53.176 54.241.53.176

1-s2.0-S2589004226005055-main-html.html

1
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GPR3 is an immediate-early gene-like GPCR regulating CREB-dependent neuronal differentiation

1
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Progesterone-driven stabilization of hybrid E/M states in amniotic epithelial cells enhances regeneration and immune modulatory capacities

1
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Spatial transcriptomics reveals the molecular signatures of prodromal and advanced α-synucleinopathy

1
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Ttc21b is required for proper forebrain neural progenitor proliferation

1
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  DOI: 10.1242/dmm.052392
  
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Protocol to enhance pre-sexual and sexual differentiation of Toxoplasma gondii using retinal cells and intestinal organoid-derived monolayers

1
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Red blood cells serve as a primary glucose sink to improve glucose tolerance at altitude

1
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  DOI: 10.1016/j.cmet.2026.01.019
  
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Local heterochromatin enrichment promotes telomere clustering and PML nuclear body assembly at telomeres

1
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Dynamic map illuminates Hippo-cMyc module crosstalk driving cardiomyocyte proliferation

1
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The succinate prodrug NV354 prevents brain lesions and late-stage motor dysfunction in mitochondrial complex I deficiency

1
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Lipid droplet-induced T cell death sustains autoimmune tissue inflammation

1
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Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux

1
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The ANGPTL3-integrin α5 axis drives retinal vascular leakage in diabetic retinopathy

1
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  DOI: 10.1186/s12967-026-07710-4
  
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Targeting PDK4 attenuates neointimal hyperplasia and regulates VSMC phenotypic Switching, Apoptosis, and autophagy

1
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Dynamic assessment of a humanized bone tumour microenvironment reveals insights into osteosarcoma primary tumour remodelling and lung metastases

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Sex peptide targets distinct higher order processing neurons in the brain to induce the female post-mating response

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54.241.53.176 54.241.53.176

2026.01.30.702807v1.full-html.html

1
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54.241.53.176/a1fb126143f6ebd2aa86840167c32224c61cfe36/2026.01.30.702807v1.full-html.html
54.241.53.176 54.241.53.176

1-s2.0-S2589004226003561-main-html.html

1
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Impact of Tau overexpression on DNA replication dynamics in centromeres of human neural progenitor cells

1
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Ploidy and neuron size impact nervous system development and function in Xenopus

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Cellular Mg2+ decrease causes a distinctive NF-κB-dependent form of cell death

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Tfam-mediated metabolic perturbation in RORγt+ lymphocytes impacts intestinal tissue homeostasis and promotes GATA3+RORγt+ innate lymphoid cells

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Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestration

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  DOI: 10.1083/jcb.202501207
  
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Bi-handed assembly chaperones regulate protein complex assembly through an intramolecular handover mechanism

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  DOI: 10.1126/sciadv.adw9158
  
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54.241.53.176 54.241.53.176

1-s2.0-S258900422600324X-main-html.html

1
1. scibot 10 Feb 2026
  
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FDCA Attenuates Neuronal Ferroptosis and Reduces Hemorrhagic Transformation After Ischemic Stroke with High Glucose

1
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Bi-handed assembly chaperones regulate protein complex assembly through an intramolecular handover mechanism

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  RRID:AB_142165
  
  DOI: 10.1126/sciadv.adw9158
  
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Precise control of transcription condensates across S phase balances linker histone expression with DNA replication, ensuring genome stability

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  DOI: 10.1016/j.molcel.2026.01.005
  
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Multi-omic analysis of guided and unguided forebrain organoids reveals differences in cellular composition and metabolic profiles

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  DOI: 10.1016/j.crmeth.2025.101295
  
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Delphinidin modulates neuroinflammation and behavioral deficits in a Parkinson’s disease mouse model

1
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  DOI: 10.1038/s41531-025-01244-0
  
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Just a little prick: careful cell contacts enabled by ceramic nanostraws

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1. scibot 04 Feb 2026
  
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  RRID:AB_143165
  
  DOI: 10.1007/s00424-026-03150-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12862038/
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Targeting the tumor cell-intrinsic ITGB2 axis inhibits melanoma progression

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1. scibot 01 Feb 2026
  
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  DOI: 10.1186/s12943-025-02527-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12744402/
Jan 2026
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Mitigating xenogeneic barriers to chimerism through Cas13-induced host attenuation

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1. scibot 30 Jan 2026
  
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  DOI: 10.1016/j.devcel.2026.01.001
  
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sciencedirect.com/science/article/pii/S1534580726000018
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Dorsal Raphe VIP Neurons Are Critical for Survival-Oriented Vigilance

2
1. scibot 29 Jan 2026
  
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  DOI: 10.1002/advs.202523809
  
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2. scibot 29 Jan 2026
  
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  DOI: 10.1002/advs.202523809
  
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202523809
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African pygmy mouse iPSCs as a model for in vitro embryogenesis, interspecies chimerism, and blastocyst complementation

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1. scibot 29 Jan 2026
  
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  DOI: 10.1016/j.crmeth.2025.101293
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12946758/
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MITF, TFEB, and TFE3 drive distinct adaptive gene expression programs and immune infiltration in melanoma

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1. scibot 28 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116499
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12828906/
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Aβ antibodies target not only amyloid plaques but also distinct brain cells and vessels

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1. scibot 28 Jan 2026
  
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  DOI: 10.1002/alz.71121
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12823779/
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Enhancer-based AAV approach for selective AADC delivery reduces motor symptoms and dyskinesia in Parkinson’s mouse models

1
1. scibot 27 Jan 2026
  
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  DOI: 10.64898/2026.01.20.700641
  
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54.241.53.176 54.241.53.176

2026.01.21.700886v1.full-html.html

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1. scibot 27 Jan 2026
  
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  AB_143165
  
  DOI: 10.64898/2026.01.21.700886
  
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54.241.53.176/bdd50a9018c213744bdf3c237d3ef5763deb458b/2026.01.21.700886v1.full-html.html
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Trigeminal ganglion interferon-γ signaling drives orofacial neuropathic pain in rats

1
1. scibot 23 Jan 2026
  
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  DOI: 10.1186/s10194-025-02242-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12801634/
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A coordinated haptic mechanism ensures efficient DNA sampling by the 8-oxoguanine glycosylase OGG1

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116872
  
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MYC binding to nascent RNA suppresses innate immune signaling by R-loop-derived RNA-DNA hybrids

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.cell.2025.12.019
  
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A neural connectivity atlas for fly flight control

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1. scibot 22 Jan 2026
  
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  DOI: 10.1016/j.cub.2025.12.024
  
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Paper-html.html

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  DOI: 10.1002/advs.202509733
  
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54.241.53.176/c6fac447a76ee033d00fb2f428e99ba927459b75/Paper-html.html
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A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking

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  DOI: 10.1083/jcb.202507084
  
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54.241.53.176 54.241.53.176

1-s2.0-S2589004226000532-main-html.html

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1. scibot 15 Jan 2026
  
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  DOI: 10.1016/j.isci.2026.114678
  
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54.241.53.176/083ea85753a70ebe103fed51d389580a2ae119f0/1-s2.0-S2589004226000532-main-html.html
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A combinatorial transcription factor screening platform for immune cell reprogramming

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1. scibot 15 Jan 2026
  
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  DOI: 10.1016/j.cels.2025.101457
  
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sciencedirect.com/science/article/pii/S240547122500290X
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NFAT mediates pro-tumorigenic inflammation in cancer-associated fibroblasts in pancreatic ductal adenocarcinoma

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1. scibot 15 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116849
  
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sciencedirect.com/science/article/pii/S2211124725016213
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BMSC-Derived Exosomal miR-21a-5p Ameliorates Blood–Brain Barrier Injury and Hemorrhagic Transformation

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1. scibot 15 Jan 2026
  
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  DOI: 10.1007/s12035-025-05650-6
  
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link.springer.com/article/10.1007/s12035-025-05650-6
elifesciences.org elifesciences.org

Establishing synthetic ribbon-type active zones in a heterologous expression system

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1. scibot 15 Jan 2026
  
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  DOI: 10.7554/eLife.98254
  
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RNF216 Variants Found in Patients With Dementia, Hypogonadotropic Hypogonadism, and Severe Ataxia Deregulate Autophagy

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1. scibot 13 Jan 2026
  
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  DOI: 10.1210/clinem/dgaf640
  
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dx.doi.org/10.1210/clinem/dgaf640

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