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Nuclear TRiC states captured in situ

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Identification and regulation of an ACC1-associated lipogenic metabolon in liver

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  DOI: 10.1016/j.molcel.2026.10.017
  
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Microbial metabolism of methotrexate produces a STAT3 signaling molecule that alleviates gut inflammation

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  DOI: 10.1016/j.chom.2026.10.005
  
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sciencedirect.com/science/article/pii/S1931312826004397
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Presynaptic filopodia form kinapses and promote convective membrane flow to sustain synchronous neurotransmitter release

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  DOI: 10.1126/sciadv.aei2661
  
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Electroconductive patch promotes heart repair by directing epicardial cells toward endothelial fate

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  DOI: 10.1016/j.stem.2026.10.006
  
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Acute peripheral nerve injury induces coordinated VNUT upregulation in primary sensory neurons and satellite glial cells in sensory ganglia

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  DOI: 10.1016/j.neulet.2026.138778
  
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Glia proliferation and heterogeneity in CMT1A: Involvement of RUNX2-Schwann cells and endoneurial fibroblasts

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Genetic GHSR deficiency and LEAP2 treatment enhance the glucose-lowering effects of liraglutide in male mice in a metabolic state-dependent manner

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sciencedirect.com/science/article/pii/S0024320526005631
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Deciphering early tau pathology events using an Alzheimer’s disease-seeded organotypic hippocampal slice culture model

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  DOI: 10.1016/j.isci.2026.118083
  
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Axonal transcriptome remodeling during PGE2 induced sensitization identifies Tnfrsf12a/FN14 as a regulator of sensory neuron excitability

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Subchronic methylmercury exposure disrupts forebrain inhibitory circuits and induces psychomotor abnormalities in mice

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  DOI: 10.1016/j.envpol.2026.129439
  
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Clusterin, through exercise-mediated liver-heart crosstalk, promotes heart regeneration after myocardial infarction

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1. scibot 05 Nov 2026
  
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  DOI: 10.1016/j.celrep.2026.118234
  
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Exposure to immune stimuli augments alveolar macrophages to acquire neutrophil antimicrobial molecules to prevent bacterial pneumonia

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1. scibot 05 Nov 2026
  
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  DOI: 10.1016/j.celrep.2026.118229
  
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A stress-adapted fiber state promotes clonal expansion of deleted mitochondrial DNA

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1. scibot 05 Nov 2026
  
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  DOI: 10.1016/j.celrep.2026.117995
  
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Oct 2026
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CK2 and DBT promote temperature compensation of the Drosophila circadian clock via distinct pathways

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1. scibot 31 Oct 2026
  
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  DOI: 10.1016/j.isci.2026.118004
  
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jnc70561-sup-0001-supinfo-html.html

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1. scibot 29 Oct 2026
  
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  DOI: 10.1111/jnc.70561
  
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54.241.53.176/f55dd922acc06a08b707fb6494d062b9e7249521/jnc70561-sup-0001-supinfo-html.html
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CASTOR1 functional inactivation drives KRAS-mutant NSCLC and therapy resistance by a noncanonical mechanism of tumor suppression

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1. scibot 28 Oct 2026
  
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  DOI: 10.1126/sciadv.aeb9836
  
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Direct CDK1 engagement underlies carbaryl-induced genotoxic cell cycle arrest

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1. scibot 23 Oct 2026
  
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  DOI: 10.64898/2026.10.01.756001
  
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54.241.53.176/52a1bc1c868f7162e25ca2c165a2f8f4cdced68e/2026.10.01.756001v2.full-html.html
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Generation of hypoimmunogenic cardiomyocytes from human induced pluripotent stem cells with TAPBP knockout

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1. scibot 22 Oct 2026
  
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  DOI: 10.1016/j.isci.2026.117933
  
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Selective USP32 inhibition reveals endosomal ubiquitin signaling and enables cell-permeable activity-based probes

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1. scibot 22 Oct 2026
  
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  DOI: 10.1016/j.chembiol.2026.09.018
  
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sciencedirect.com/science/article/pii/S2451945626003673
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Social Isolation Causes Behavioural Abnormalities and Reduces Synaptic Proteins in the Brains of Drosophila

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  DOI: 10.3390/biology15191721
  
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mdpi.com/2079-7737/15/19/1721
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Neural coordination of wing and leg movements during a terrestrial threat display

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  DOI: 10.1016/j.cub.2026.09.056
  
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Prospero prevents lineage-specific loss and gain by regulating cyclin E and mitosis during Drosophila neurogenesis

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  DOI: 10.1038/s44319-026-00947-6
  
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link.springer.com/article/10.1038/s44319-026-00947-6
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Striatal astrocyte μ-crystallin (Crym) loss contributes to early-stage Huntington’s disease pathophysiology

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1. scibot 15 Oct 2026
  
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  DOI: 10.1016/j.neuron.2026.08.027
  
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cell.com/neuron/fulltext/S0896-6273(26)00678-1
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Molecular mechanisms underlying the effectiveness of triiodothyroacetic acid (Triac) in patients with resistance to thyroid hormone β (RTHβ): a multicentre, international, retrospective cohort study

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  DOI: 10.1016/j.ebiom.2026.106512
  
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Integrated Genetic Screening Identifies FEN1 as a Selective Vulnerability and Temozolomide Resistance Mediator in Glioblastoma Stem Cells

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1. scibot 12 Oct 2026
  
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  DOI: 10.1158/2767-9764.CRC-26-0150
  
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Lipid metabolism remodeling in human cardiomyocyte differentiation and maturation

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  DOI: 10.1016/j.isci.2026.117821
  
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Dopamine-induced mitochondrial dysfunction activates cGAS-sTING to drive IL-6 secretion in macrophages

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  DOI: 10.1016/j.celrep.2026.118118
  
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Generation of a PKP2 (c.1171-2 A > G) mutant human embryonic stem cell line using adenine base editing

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1. scibot 10 Oct 2026
  
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  DOI: 10.1016/j.scr.2026.104113
  
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Targeting BCL11B-mediated JAK2/STAT3 activation: A novel therapeutic strategy for Parkinson’s disease

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  DOI: 10.1016/j.isci.2026.117833
  
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DND1-NANOS3 shapes the PGC transcriptome via a heptanucleotide sequence in mRNA 3′ UTRs

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  DOI: 10.1016/j.molcel.2026.09.010
  
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Spatial Lipidomics and Transcriptomics Reveal Nicotine-Mediated Restoration of Lipid Homeostasis in Parkinson’s Disease

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1. scibot 08 Oct 2026
  
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  DOI: 10.1016/j.jlr.2026.101163
  
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sciencedirect.com/science/article/pii/S0022227526001938
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Deoxysphingolipids activate cGAS-STING and enhance antitumor immunity

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  DOI: 10.1016/j.celrep.2026.118089
  
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Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

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1. scibot 08 Oct 2026
  
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  DOI: 10.1002/advs.77733
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13624869/
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STX1B variant-specific synaptic dysfunction is associated with network hyperexcitability in human iPSC-derived neurons

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1. scibot 07 Oct 2026
  
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  DOI: 10.1016/j.ebiom.2026.106451
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13560554/
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Berberine and Etoposide Exert Synergistic Anticancer Effects in A431 Epidermoid Carcinoma Cells

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1. scibot 06 Oct 2026
  
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  DOI: 10.1021/acsomega.6c06421
  
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Cervical lymphadenectomy impairs brain lymphatic clearance and synaptic proteostasis

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A TMEM119-tankyrase axis restrains microglial phagocytosis to maintain memory and enables pharmacological forgetting

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Proteomic and functional profiling of suspended jejunal enteroids reveals pharmacokinetic fidelity to native intestine

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Physiological elasticity and topography modulate in vitro prostate cancer cell behavior

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Circadian control of dopaminergic signaling to the mushroom body regulates sleep through rhythmic Pka-C1 transcription in Drosophila

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Targeted O-GlcNAcylation enables functional rewiring of c-Myc

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Methyl-donor inhibitors relax 3D genome structures to promote totipotent reprogramming

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p63 and p73 drive cutaneous squamous cell carcinoma through convergent transcriptional control of EGFR signaling

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A bifunctional ARHGEF17-AS1 locus encodes MSEP, a protein that supports mitotic spindle organization

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Cargo crosslinking nucleates AP-1 lattice formation

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Loss of polr1c disrupts myelination in a zebrafish model of POLR1C-associated disease

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AAV-delivered TurboRFP enables streamlined tracing and analysis of corticospinal tract sprouting

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RhoA through its various effectors mediate mitochondrial fragmentation in polycystic kidney disease

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Adipose ILC2s depend on acetyl-CoA carboxylase 1 to maintain metabolic health

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Post-transcriptional regulation maintains neurogenic potential of human neural progenitor cells

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Macrophages promote collagen deposition through circadian regulation of fibroblasts

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Excessive activation of the RAS/MAPK pathway triggers adult-onset motor axonal degeneration

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The spindle-associated antisense RNA ARHGEF17-AS1 functionally contributes to mitotic spindle integrity

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Spatially varying mRNA decay contributes to sharpening the even-skipped expression pattern in the Drosophila embryo

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Lymph node extracellular matrix skews the immune function of human fibroblastic reticular cells

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Kappa opioids suppress histaminergic itch by inhibiting mediodorsal thalamus-projecting claustrum glutamatergic neurons

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SARS-CoV-2 spike-armed vesicular stomatitis virus recapitulates severe COVID-19 acute respiratory distress syndrome in mice

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FEBS Press

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Versatile twin layer macromolecular fibers for advanced tissue engineering applications

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The insulin/IGF axis is critically important for controlling gene transcription in the podocyte

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IGF2 acts downstream of Hippo signaling to regulate organ growth and restore liver regeneration in aging

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Linalool enables reversible immobilization for high-resolution in vivo imaging during regeneration in Schmidtea mediterranea

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A microbial chromatin remodeler drives gastric cancer progression and immune evasion by reprogramming the host epigenome

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Eimeria bovis-infected host cell-bystander cell interactions are essential for effective macromeront formation

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ATP13A4 gates extracellular polyamine levels to control excitatory synaptogenesis

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Insulin receptor substrate 2 regulates placental syncytiotrophoblast differentiation at the maternal-fetal interface

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Aging microenvironment induces CD8+ T cell exhaustion by suppressing hepatic β-hydroxybutyrylate synthesis

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Local lactate-driven H3K18 lactylation impairs anti-influenza immunity through NRF2-dependent dendritic cell dysfunction

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HDAC1 lactylation drives diabetic retinopathy by orchestrating a pro-angiogenic epigenetic program

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The complete gustatory connectome of adult Drosophila reveals how taste guides feeding, foraging, and social behavior

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s12951-026-04972-4_reference-html.html

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Fast tumor accumulation and payload release of c-Met targeting aptamer-drug conjugate enables robust anti-tumor efficacy

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An IRAK1-snRNA axis activates ATM to promote accurate repair within transcriptionally active chromatin

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Single-cell transcriptomics reveals that tenocyte-derived MIF contributes to tendon injury pathogenesis

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MORC1 coordinates TRIM28 interaction and nuclear condensate formation for transposon silencing

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STX1B variant-specific synaptic dysfunction is associated with network hyperexcitability in human iPSC-derived neurons

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Sex-specific effects of therapeutic hypothermia on short- and long-term microglial and astrocytic reactivity after severe neonatal hypoxia–ischemia

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PIWIL4 regulates gene expression and piRNA levels in RSV-infected airway epithelial cells

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FASN-mediated de novo lipogenesis promotes ceramide accumulation and myocardial damage in arrhythmogenic cardiomyopathy

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Stroma-oriented tumor microenvironment facilitates intraosseous ameloblastoma tumor growth

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TRPV4-driven ATP release activates CFTR through ADORA2B and P2RY2 receptors in the airway epithelium

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Targeting pro-senescent PTGS2+ macrophages alleviates chondrocyte senescence and osteoarthritis progression

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Sphingosine kinase 2 regulates adipocyte browning and whole-body metabolism

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Male and female mice scent mark during social communication regardless of sexual motivation or partner identity

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Adaptive immune responses are not causal to SGN death after kanamycin-induced hair cell loss

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Metabolic and developmental rate divergence between serially homologous cells underlies an evolutionary innovation in Drosophila

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Complementary roles of cell-type-specific plasticity in shaping neocortical dynamics for learning action timing

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Repurposing Nelfinavir: AIM2 inflammasome-associated anti-tumor effects in Glioblastoma

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Anatomical Investigation Reveals a Second Olfactory System in Locusts

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Hcp1 mediates multinucleated giant cell formation through redirecting arginine metabolism during Burkholderia pseudomallei infection

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GATA1 repression-mediated ADRB2/cAMP/PKA signaling activation underlies the antidepressant effects of targeted geniposide delivery

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Dynamic characterization of pathological and functional deterioration in a mouse model of optic neuritis related to neuromyelitis optica spectrum disorder

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Astrocytic NFIX regulates thalamocortical circuits through GABA and purinergic signaling

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FKBP51 inhibition by SAFit2 modulates tau pathology and cognitive deficits in PS19 mice

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AURORA A interacts with DICER and SETD2 to promote S-phase progression

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Human iPSC-derived heart valve-like assembloids model valve development and disease pathology

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Exercise is associated with attenuated aging-related osteoporosis through TMAO alpha Klotho inflammasome signaling

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Elongating human heart organoids recapitulate early cardiac morphogenesis and axial organization

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RASA1 deficiency aggravates the lesion burden of cerebral cavernous malformations via the Ras/Raf/MAPK pathway

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KATP channel functional remodeling is associated with neuroinflammatory and dopaminergic alterations under metabolic stress in female mice

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Aβ Antibodies Target Not Only Amyloid Plaques But Also Distinct Brain Cells And Vessels

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Neuron type-specific translatomes in dorsal hippocampus during early memory consolidation

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Glutamine-restricted diets restore sensitivity to KRASG12D inhibitor through the reversal of ANXA1 mediated metabolic reprogramming

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A macrophage-intestinal organoid co-culture model captures balanced epithelial homeostasis and inflammation

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Simultaneous, real-time tracking of many neuromodulatory signals with multiplexed optical recording of sensors on a micro-endoscope

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  DOI: 10.1016/j.neuron.2026.07.008
  
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α-Satellite RNA maintains centromeric cohesion through R-loops

1
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Targeting host lipogenesis with a diarylamide inhibitor disrupts SARS-CoV-2 replication

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The deficiency of KIF2C leads to abnormal distribution of cortical neurons and behavioral deficits in mice

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Torsins organize CLCC1 assembly to safeguard ER bilayer and lipid homeostasis

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CD163+ red pulp macrophages interact with marginal metallophilic macrophages during blood-stage malaria to maintain splenic architecture

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CRISPR/Cas9-mediated generation of a homozygous MT4 knockout mouse embryonic stem cell line

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BPS Publications

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Glycolytic suppression of cell adhesion promotes thyroid morphogenesis in response to nutrition

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Milk osteopontin alters the infant microbiome to drive DC hematopoiesis and disease tolerance

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Repurposing simeprevir uncovers a druggable KPNB1-p65-BCL2 survival axis in cancer

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Transcriptional regulation of disease-relevant microglial activation programs

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Fstl1 determines luminal size of mouse trachea through negative regulation of BMP4 signaling

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Acute AKT signaling increases glucose phosphorylation and contribution to glycogen in hepatocytes

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Human-specific SRGAP2 paralogs synchronize neotenic microglial maturation and synaptic development

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Developmentally Regulated Expression and Activity of Sulphotransferases in the Rat Choroid Plexuses

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Divergent co-transmission by a predictive motor circuit modulates auditory processing

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Therapeutic Gfral silencing via antisense oligonucleotides ameliorates cancer-associated cachexia and extends survival in tumor-bearing mice

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The actin crosslinker Fimbrin is required for force sensing at tricellular junctions

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Lactation increases food seeking and palatable feeding through mesolimbic dopamine signaling in mice

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High and intermittent hydrostatic pressure promotes maturation of engineered cardiac tissues derived from human pluripotent stem cells

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Efficient generation of human cDC1-like cells to detect and enhance tumor-reactive T cells via CD4+ T cell help

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Condensates of the chromatin regulator ANKRD11 restrict hypertranscribed genes to safeguard development

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Host transcriptional corepressor TLE1 is commonly exploited by RNA viruses for replication

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A single-component optogenetic toolkit for reversible visualization and programmable control of microtubule dynamics

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AXL phosphosite mapping links FAK1 and YAP1 signaling to erlotinib resistance in EGFR-mutant lung cancer

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Identification of a novel isoform of Slc26a4 by single-cell RNA-sequencing of pendrin-expressing cells in the cochlea

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1-s2.0-S2212877826001043-main-html.html

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Localized mRNAs and protein synthesis in cortical layer 1

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The autoimmune regulator (AIRE) is a target of the E3-Ubiquitin ligase Seven-in-absentia homolog 1 (SIAH1)

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Ethological learning during the critical period resets synaptic setpoints in mouse binocular visual cortex

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Amyloid-bodies in the evolution of malignancies

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Oxygen-stable streptolysin O variant enables mitochondrial ATP synthesis analysis in minimal cells blood and tissues

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Complex II inhibitor-loaded hollow piezoelectric nanocarriers potentiate respiration-driven piezocatalytic therapy for malignant pleural effusion

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Medial entorhinal-hippocampal desynchronization parallels the emergence of memory impairment in a mouse model of Alzheimer’s disease pathology

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Aberrant Pain Phenotypes Emerge Following Prenatal Hypoxic-Ischemic Injury in a Rabbit Model of Cerebral Palsy

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IDH1 Reprograms Nucleotide Metabolism by Inducing Chromatin Remodeling and DHODH Transcription to Drive Chemoresistance in Nasopharyngeal Carcinoma

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Orb2 RNA-binding activity promotes neural stem cell development and brain growth in Drosophila larvae

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MEN1 Promotes Ferroptosis by Disrupting CD44 Alternative Splicing to Suppress Lung Cancer

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Cytotoxic CD8+ T Cells Downregulate GPX4 to Promote Ferroptosis in Melanoma that Drives Antitumor Immunity

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Identification of novel genes with enriched expression in human intermediate progenitors reveals a key role for CDKN3 in cortical development

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A telomerase-SUCLG2 signaling axis drives drug resistance by protecting persister cells

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Development of an in vivo, screenable, split-luciferase based model of huntingtin multimerization

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A human iPSC model with LATS1/2 knockdown (MUSIi012-A-9) for investigating Hippo signaling in stem cell

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Generation of two CASK patient-derived human induced pluripotent stem cell lines to study CASK-related disorders

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Depletion of CX3CR1+ macrophages results in disrupted functionality and immune surveillance within epididymis and testis

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An IGF2BP3-dependent metabolic circuit governs macrophage recruitment and immunosuppression in glioblastoma

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Chronic glucocorticoid exposure disrupts lactate homeostasis and hippocampal neurogenesis by reducing cerebrovascular monocarboxylate transporter 1, leading to behavioral abnormalities in mice

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Targeting cytokine-like protein FAM3D alleviates atherosclerosis

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Gut commensal Bacteroides-derived pantothenic acid alleviates metabolic syndrome

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A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss

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Prefrontal-medullary circuitry is necessary for sex-specific responses to metabolic stress in rats

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BPS Publications

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BPS Publications

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Trans-synaptic signaling through GRID1/glutamate receptor delta-1 and CBLN1/cerebellin-1 facilitates autophagic flux in central amygdala and prevents chronic pain

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Myc sustains sex-biased organ zonation in the Drosophila intestine

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TUSC3 serves as a rate-limiting gatekeeper of a glycan-mediated ER triage checkpoint for BMP4/Dpp

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Unmyelinated nerve fibers distributed in the human crural fascia of Thiel-embalmed cadavers

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ssrn-6989328-html.html

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yu-et-al-2026-mir-339-5p-impairs-myogenic-proliferation-and-differentiation-by-repressing-contractile-gene-programs-in-html.html

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Metabolic state determines the brain and direct islet effects of liraglutide on enhanced insulin secretion

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Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer

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Generation of iPSC and isogenic gene-corrected lines from a patient with Shwachman Diamond syndrome

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Cadherin regulation of endoplasmic reticulum-plasma membrane contact sites

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Dynamicity of Topoisomerase 1 binding at super-enhancers regulates TLR-responsive gene expression program in macrophages

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Cellular prion protein suppresses colitis and colorectal carcinogenesis via modulating inflammatory responses

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Disrupted mitochondrial dynamics activate RNA-sensing innate immunity through mitochondrial RNA release

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Recurrent ZC3H18 mutations stabilize oncogenic endogenous retroviral RNA

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δ-catenin controls layer-specific transcriptional maturation of astrocytes via Zbtb20

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Glucose concentration of neuronal media formulations influences PINK1-dependent mitophagy in human iNeurons

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Genetic dissection of the role of Piga and Pgap2 in the embryonic mouse brain

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Targeting CCDC90B restores intestinal stem cell function under hyperuricemic stress

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Quantitative molecular cartography of emergency myelopoiesis reveals conserved modules of hematopoietic activation

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ssrn-6932261-html.html

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  DOI: 10.2139/ssrn.6932261
  
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ssrn-6690663-html.html

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ssrn-6690772-html.html

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54.241.53.176/9a49be414064671af57d7d33ea2ae65a3384fe63/ssrn-6690772-html.html
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CNTN6 Modulates Slit-Robo Signaling in Cortical GABAergic Interneuron Migration

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  DOI: 10.1007/s12264-026-01637-y
  
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Nuclear CK1δ as a critical determinant of PER:CRY complex dynamics and circadian period

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DPY30 is an epigenetic decoupler linking replication stress to immunoediting in pancreatic cancer

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  DOI: 10.1158/0008-5472.CAN-25-3849
  
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DKK1 Targeting in Corneal Schwann Cells Rescues Axonal Regeneration and Mechanosensory Function After Corneal Injury

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Glucose concentration of neuronal media formulations influences PINK1-dependent mitophagy in human iNeurons

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The molecular mechanism of melatonin in regulating osteoporosis based on the RANKL/OPG signaling axis

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Impact of O-GlcNAcylation elevation on mitophagy and glia in the dentate gyrus

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Pro-repair properties of a human embryonic stem cell-derived astrocyte cell therapy in demyelinating disorders

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Suppression of ATM kinase signaling accelerates cellular senescence

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Electron transport chain complex I and mitochondrial fusion regulate ROS for differentiation in Drosophila neural stem cells

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Chemical Modulation of Miro1 Alleviates Cell-Type-Specific Vulnerabilities in Friedreich’s Ataxia

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STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation

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  DOI: 10.1016/j.celrep.2026.117497
  
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Spermidine suppresses glial inflammation and parkinsonian abnormalities in ATP13A2 deficiency

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  DOI: 10.64898/2026.05.23.26353575
  
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Chemogenetic activation of the amygdala core nucleus increases aggression in chickens

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Long-term reversal of Duchenne muscular dystrophy via circular arRNA-guided exon skipping in monkeys and humans

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  DOI: 10.1016/j.cell.2026.05.030
  
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Methamphetamine potentiates the use of outcome-specific associations via a hypothalamic-dopamine circuit

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