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The E3 ligase RNF32 controls the IκB kinase complex and NF-κB signaling in intestinal stem cells

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  DOI: 10.1016/j.molcel.2025.10.005
  
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sciencedirect.com/science/article/pii/S1097276525008226
Sep 2025
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Ubiquitination-activated TAB–TAK1–IKK–NF-κB axis modulates gene expression for cell survival in the lysosomal damage response

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  DOI: 10.7554/eLife.106901
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12459955/
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The E3 ubiquitin ligase SIAH1 targets a bacterial pore-forming toxin to facilitate xenophagy

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  DOI: 10.1016/j.celrep.2025.116257
  
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sciencedirect.com/science/article/pii/S2211124725010289
Aug 2025
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A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia

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sciencedirect.com/science/article/pii/S0092867425008657
Jun 2024
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Bacterial esterases reverse lipopolysaccharide ubiquitylation to block host immunity

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sciencedirect.com/science/article/pii/S193131282400132X
Apr 2024
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Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation

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  DOI: 10.1038/s41594-024-01294-7
  
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Individual Atg8 paralogs and a bacterial metabolite sequentially promote hierarchical CASM-xenophagy induction and transition

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Feb 2024
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Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation

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  DOI: 10.1101/2023.12.20.572718
  
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biorxiv.org/content/10.1101/2023.12.20.572718v1
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Prenatal hormone stress triggers embryonic cardiac hypertrophy outcome by ubiquitin-dependent degradation of mitochondrial mitofusin 2

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Dec 2023
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NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62

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ncbi.nlm.nih.gov/pmc/articles/PMC10730909/
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Ubiquiton—An inducible, linkage-specific polyubiquitylation tool

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  DOI: 10.1016/j.molcel.2023.11.016
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10804999/
Nov 2023
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The ubiquitin conjugase Rad6 mediates ribosome pausing during oxidative stress

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Oct 2023
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Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival

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1. scibot 13 Oct 2023
  
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  DOI: 10.1101/2023.10.06.560832
  
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biorxiv.org/content/10.1101/2023.10.06.560832v1
Aug 2023
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Art2 mediates selective endocytosis of methionine transporters during adaptation to sphingolipid depletion

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  DOI: 10.1242/jcs.260675
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10399987/
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Senescent cells form nuclear foci that contain the 26S proteasome

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sciencedirect.com/science/article/pii/S2211124723008914
Jul 2023
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NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-condensation with p62

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1. scibot 19 Jul 2023
  
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  DOI: 10.1101/2023.06.05.543428
  
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52.53.155.43/5185b06857919afc7fae38712332798a8a903a3a/2023.06.05.543428v1.full-html.html
Feb 2023
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Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin β-1 granules

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1. scibot 24 Feb 2023
  
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sciencedirect.com/science/article/pii/S2211124723001456
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The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system

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  DOI: 10.1038/s41467-023-36058-2
  
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nature.com/articles/s41467-023-36058-2
Nov 2022
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LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus

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1. scibot 19 Nov 2022
  
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  DOI: 10.15252/embj.2022112006
  
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embopress.org/doi/10.15252/embj.2022112006
Oct 2022
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The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma

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nature.com/articles/s41419-022-05318-2
Sep 2022
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Identification of CUL4A-DDB1-WDFY1 as an E3 ubiquitin ligase complex involved in initiation of lysophagy

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The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction

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Aug 2022
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The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity

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  DOI: 10.1016/j.cell.2016.07.019
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5002269/
May 2022
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Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes

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1. scibot 26 May 2022
  
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Mar 2022
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A trio of ubiquitin ligases sequentially drives ubiquitylation and autophagic degradation of dysfunctional yeast proteasomes

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Linkage reprogramming by tailor-made E3s reveals polyubiquitin chain requirements in DNA-damage bypass

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Oct 2021
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TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease

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  DOI: 10.1016/j.neuron.2021.09.031
  
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Humanin-induced autophagy plays important roles in skeletal muscle function and lifespan extension

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Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains

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  DOI: 10.1016/j.celrep.2021.109777
  
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sciencedirect.com/science/article/pii/S2211124721012316
Aug 2021
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Untitled document

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  DOI: 10.1016/j.celrep.2019.04.015
  
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Untitled document

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  DOI: 10.1016/j.celrep.2019.02.067
  
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Untitled document

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  DOI: 10.7554/eLife.22416
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5340530/
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Rewiring of the ubiquitinated proteome determines ageing in C. elegans

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  DOI: 10.1038/s41586-021-03781-z
  
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Untitled document

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  DOI: 10.7554/eLife.24425
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5484619/
Jul 2021
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Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death

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1. scibot 31 Jul 2021
  
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  Rabbit monoclonal anti-K63 Ubiquitin
  
  DOI: 10.1016/j.celrep.2019.11.014
  
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sciencedirect.com/science/article/pii/S2211124719314858
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Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination

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1. scibot 23 Jul 2021
  
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  DOI: 10.1083/jcb.202006043
  
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rupress.org/jcb/article/220/6/e202006043/211984/Parkin-independent-mitophagy-via-Drp1-mediated
Apr 2021
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Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome

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1. scibot 23 Apr 2021
  
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  RRID:AB_1587580
  
  DOI: 10.1016/j.cell.2021.03.048
  
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Nov 2020
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Identification of ubiquitin Ser57 kinases regulating the oxidative stress response in yeast

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1. scibot 12 Nov 2020
  
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  DOI: 10.7554/eLife.58155
  
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Sep 2020
rupress.org rupress.org

Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy

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1. scibot 11 Sep 2020
  
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  RRID:AB_1587580
  
  DOI: 10.1083/jcb.201912144
  
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genesdev.cshlp.org genesdev.cshlp.org

Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne

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1. scibot 04 Sep 2020
  
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  K63
  
  DOI: 10.1101/gad.332395.119
  
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Structural Basis for the Inhibitory Effects of Ubistatins in the Ubiquitin-Proteasome Pathway

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  RRID:AB_1587580
  
  DOI: 10.1016/j.str.2017.10.007
  
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AUTACs: Cargo-Specific Degraders Using Selective Autophagy

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1. scibot 13 Jan 2020
  
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  RRID:AB_1587580
  
  DOI: 10.1016/j.molcel.2019.09.009
  
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The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8

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  RRID:AB_1587580
  
  DOI: 10.15252/embj.2019102361
  
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MST1 Negatively Regulates TNFα-Induced NF-κB Signaling through Modulating LUBAC Activity

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1. scibot 13 Jan 2020
  
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  RRID:AB_1587580
  
  DOI: 10.1016/j.molcel.2019.01.022
  
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Nov 2018
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Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy

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1. scibot 05 Nov 2018
  
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Metal Sensing by the IRT1 Transporter-Receptor Orchestrates Its Own Degradation and Plant Metal Nutrition

1
1. scibot 05 Nov 2018
  
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  RRID:AB_1587580
  
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Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

1
1. scibot 05 Nov 2018
  
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  RRID:AB_1587580
  
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Nov 2017
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Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling

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Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling

1
1. scibot 08 Nov 2017
  
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  AB_1587580
  
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Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy

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1. scibot 08 Nov 2017
  
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  AB_1587580
  
  Curator: @chewbeccax
  
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elifesciences.org elifesciences.org

Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses

1
1. scibot 08 Nov 2017
  
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  AB_1587580
  
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elifesciences.org/articles/24425
elifesciences.org elifesciences.org

YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB

1
1. scibot 08 Nov 2017
  
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  AB_1587580
  
  Curator: @kaitlinsung
  
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Untitled document

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europepmc.org/articles/PMC5002269/table/undtbl1/
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Untitled document

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Untitled document

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The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity

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  AB_1587580
  
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