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A bioavailable GPX4 inhibitor for ferroptosis induction in vivo and tumor suppression

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1. scibot 07 Nov 2026
  
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  DOI: 10.1016/j.cell.2026.09.053
  
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cell.com/cell/abstract/S0092-8674(26)01200-6
Oct 2026
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Distant lymph nodes compensate for resected tumor-draining lymph nodes during cancer immunotherapy

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1. scibot 03 Oct 2026
  
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  DOI: 10.1016/j.immuni.2026.09.009
  
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sciencedirect.com/science/article/pii/S1074761326003845
Sep 2026
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Cyclin E-CDK2 regulates cancer cell transcriptional program and response to immunotherapy through BRD4

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1. scibot 04 Sep 2026
  
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  DOI: 10.1016/j.molcel.2026.08.007
  
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sciencedirect.com/science/article/pii/S109727652600554X
Aug 2026
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Sensory neurons shape γδ T cell effector programs to control psoriasiform inflammation

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1. scibot 07 Aug 2026
  
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  DOI: 10.1016/j.jid.2026.07.021
  
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sciencedirect.com/science/article/pii/S0022202X26027259
Jul 2026
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Serum meprin α levels for the detection of systemic inflammatory response syndrome

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1. scibot 21 Jul 2026
  
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  DOI: 10.1186/s10020-026-01570-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13380840/
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A MERTK-Targeting Antibody-Drug Conjugate Selectively Depletes M2 Tumor-Associated Macrophages and MERTK-Expressing Cancer Cells

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1. scibot 12 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-2998
  
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aacrjournals.org/cancerres/article/86/8/2024/782620/A-MERTK-Targeting-Antibody-Drug-Conjugate
Jun 2026
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Macrophage-mediated brain-bone marrow crosstalk promotes chronic stress-induced glioma growth

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1. scibot 22 Jun 2026
  
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sciencedirect.com/science/article/pii/S1535610826002631
May 2026
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Newly isolated human-derived Lactobacillus fermentum strain stimulates IFN-γ-secreting CD8+ T cells for enhanced anti-cancer immunity

1
1. scibot 01 May 2026
  
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  DOI: 10.1016/j.isci.2026.115642
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13125905/
Dec 2025
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Microbial-derived immunostimulatory small molecule augments anti-PD-1 therapy in lung cancer

1
1. scibot 20 Dec 2025
  
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  DOI: 10.1016/j.xcrm.2025.102519
  
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sciencedirect.com:5037/science/article/pii/S2666379125005920
Nov 2025
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Fatty acids modulate the colorectal cancer immune microenvironment via regulating the interaction and transactivation of PPARα/δ and P53

1
1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116623
  
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sciencedirect.com:5037/science/article/pii/S2211124725013956
Sep 2025
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Control of Inflammatory Response by Tissue Microenvironment

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1. scibot 24 Sep 2025
  
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  DOI: 10.1101/2024.05.10.592432
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11118380/
Jul 2025
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Structure of gut microbial glycolipid modulates host inflammatory response

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1. scibot 23 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.05.016
  
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sciencedirect.com/science/article/pii/S0092867425005665
May 2025
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Semaphorin7A and PD-L1 cooperatively drive immunosuppression during mammary involution and breast cancer

1
1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115676
  
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sciencedirect.com/science/article/pii/S2211124725004474
Feb 2025
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Enhanced viability and functional maturity of iPSC-derived islet organoids by collagen-VI-enriched ECM scaffolds

1
1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.stem.2025.02.001
  
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sciencedirect.com/science/article/pii/S1934590925000402
Nov 2024
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In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy

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1. scibot 20 Nov 2024
  
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  DOI: 10.1016/j.ccell.2024.10.009
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11561369/
Sep 2024
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Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity

1
1. scibot 27 Sep 2024
  
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  DOI: 10.1084/jem.20231835
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10965393/
Jul 2024
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Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.ccell.2024.06.001
  
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cell.com/cancer-cell/abstract/S1535-6108(24)00226-5
Mar 2024
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FcγRIIB is an immune checkpoint limiting the activity of Treg-targeting antibodies in the tumor microenvironment

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1. scibot 06 Mar 2024
  
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  DOI: 10.1158/2326-6066.CIR-23-0389
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10911703/
Dec 2023
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Metabolic diversity in commensal protists regulates intestinal immunity and trans-kingdom competition

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1. scibot 16 Dec 2023
  
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  DOI: 10.1016/j.cell.2023.11.018
  
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sciencedirect.com/science/article/pii/S0092867423012710
Nov 2023
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Prostate cancer cell-derived exosomal IL-8 fosters immune evasion by disturbing glucolipid metabolism of CD8+ T cell

1
1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113424
  
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sciencedirect.com/science/article/pii/S2211124723014365
Oct 2023
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Gut microecology may be involved in pathogenesis of Hashimoto's thyroiditis by reducing production of hydrogen sulfide

2
1. scibot 27 Oct 2023
  
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  DOI: 10.1210/clinem/dgad588
  
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  DOI: 10.1210/clinem/dgad588
  
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52.53.155.43/6ea0af8bdeaa6d30f41b089479d8363acec26b33/dgad588-html.html
Aug 2023
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CTLA-4 blockade induces CD4+ T cell IFNγ-driven microglial phagocytosis and anti-tumor function in glioblastoma

1
1. scibot 12 Aug 2023
  
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  DOI: 10.1016/j.immuni.2023.07.015
  
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sciencedirect.com/science/article/abs/pii/S107476132300328X
Apr 2023
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Restraint of IFN-γ expression through a distal silencer CNS–28 for tissue homeostasis

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1. scibot 12 Apr 2023
  
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  DOI: 10.1016/j.immuni.2023.03.006
  
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sciencedirect.com/science/article/pii/S1074761323001267
Nov 2022
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STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation

1
1. scibot 29 Nov 2022
  
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  DOI: 10.1016/j.immuni.2022.11.001
  
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sciencedirect.com/science/article/pii/S107476132200591X
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

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1. scibot 26 Jan 2022
  
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  DOI: 10.7554/eLife.74623
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8776253/
Aug 2021
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CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment

1
1. scibot 03 Aug 2021
  
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  DOI: 10.1016/j.cell.2021.07.015
  
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sciencedirect.com/science/article/pii/S0092867421008564
Apr 2021
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Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis

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1. scibot 27 Apr 2021
  
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  DOI: 10.1016/j.cell.2021.02.048
  
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sciencedirect.com/science/article/pii/S0092867421002373
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Co-option of Neutrophil Fates by Tissue Environments

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1. scibot 24 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.10.003
  
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sciencedirect.com/science/article/pii/S009286742031309X
Feb 2021
www.cell.com www.cell.com

Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies

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1. scibot 27 Feb 2021
  
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  DOI: 10.1016/j.ccell.2020.08.001
  
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cell.com/cancer-cell/abstract/S1535-6108(20)30375-5
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6775781/
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Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1934590917304551
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A Combination of Ontogeny and CNS Environment Establishes Microglial Identity

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0896627318303866
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Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1074761318300888
Nov 2017
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IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S155041311730342X