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Tumors hijack macrophages for iron supply to promote bone metastasis and anemia

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1. scibot 04 Sep 2025
  
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  DOI: 10.1016/j.cell.2025.08.013
  
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sciencedirect.com/science/article/pii/S0092867425009274
Jul 2025
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Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity

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1. scibot 23 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.018
  
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Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.06.018
  
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cell.com/cell/fulltext/S0092-8674(25)00684-1
Jun 2025
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De-coupling immune parameters and toxicity associated with IL-12 agonism

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115840
  
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sciencedirect.com/science/article/pii/S2211124725006114
May 2025
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Protocol for in vivo lineage tracing of regeneration-associated macrophages from injured skeletal muscle of adult mice

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.xpro.2025.103844
  
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Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.04.007
  
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sciencedirect.com/science/article/pii/S1535610825001667
Apr 2025
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A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection

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1. scibot 24 Apr 2025
  
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An erythroid-biased FOShi hematopoietic multipotent progenitor subpopulation contributes to adaptation to chronic hypoxia

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.stem.2025.03.010
  
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Mar 2025
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Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity

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1. scibot 24 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102035
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00108-9
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TRPM2 overactivation drives hyperlipidemia-induced dysfunction of myeloid cells and neurovascular units

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.101998
  
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sciencedirect.com/science/article/pii/S2666379125000710
Jan 2025
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Bi-directional communication between intrinsic enteric neurons and ILC2s inhibits host defense against helminth infection

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1. scibot 31 Jan 2025
  
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  DOI: 10.1016/j.immuni.2025.01.004
  
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Dec 2024
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Different effects of fatty acid oxidation on hematopoietic stem cells based on age and diet

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.stem.2024.11.014
  
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1-s2.0-S2589004224027755-main-html.html

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111548
  
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52.53.155.43/db6bd63f509ce2b1671194beaf08c82cb9e01ddc/1-s2.0-S2589004224027755-main-html.html
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The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.10.044
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11671030/
Nov 2024
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The immune landscape of murine skeletal muscle regeneration and aging

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1. scibot 20 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114975
  
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sciencedirect.com/science/article/pii/S2211124724013263
Aug 2024
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CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes

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1. scibot 30 Aug 2024
  
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  DOI: 10.1016/j.immuni.2024.07.024
  
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Jul 2024
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Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114506
  
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A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation

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1. scibot 12 Jul 2024
  
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  DOI: 10.1016/j.cmet.2024.06.010
  
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Apr 2024
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Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance

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1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114072
  
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Dec 2023
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Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection.

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1. scibot 21 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108570
  
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FLT3L-dependent dendritic cells control tumor immunity by modulating Treg and NK cell homeostasis

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1. scibot 20 Dec 2023
  
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  DOI: 10.1016/j.xcrm.2023.101256
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10772324/
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Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis

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1. scibot 02 Dec 2023
  
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  DOI: 10.1016/j.cell.2023.11.002
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10757650/
Nov 2023
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Bcl6 is a subset-defining transcription factor of lymphoid tissue inducer-like ILC3

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113425
  
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CD115+ monocytes protect microbially experienced mice against E. coli-induced sepsis

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1. scibot 03 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113345
  
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Jun 2023
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R274X-mutated Phf6 increased the self-renewal and skewed T cell differentiation of hematopoietic stem cells

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1. scibot 01 Jun 2023
  
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  DOI: 10.1016/j.isci.2023.106817
  
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May 2023
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Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging

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1. scibot 05 May 2023
  
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  DOI: 10.1016/j.stem.2022.06.012
  
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sciencedirect.com/science/article/pii/S1934590922002612
Apr 2023
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Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment

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1. scibot 07 Apr 2023
  
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  DOI: 10.1016/j.cell.2023.03.011
  
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cell.com/cell/fulltext/S0092-8674(23)00271-4
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Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup

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1. scibot 07 Apr 2023
  
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  DOI: 10.1016/j.immuni.2023.03.008
  
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cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory

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1. scibot 05 Apr 2023
  
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  DOI: 10.1126/sciimmunol.abq7432
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9835709/
Mar 2023
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Endothelial and Leptin Receptor+ cells promote the maintenance of stem cells and hematopoiesis in early postnatal murine bone marrow

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  DOI: 10.1016/j.devcel.2023.02.003
  
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Jan 2023
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Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors

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  DOI: 10.1016/j.celrep.2022.111930
  
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Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice

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1. scibot 06 Jan 2023
  
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  DOI: 10.1016/j.isci.2022.105769
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9804112/
Sep 2022
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Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin

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1. scibot 21 Sep 2022
  
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  DOI: 10.1016/j.celrep.2022.111390
  
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sciencedirect.com/science/article/pii/S221112472201227X
Aug 2022
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DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential

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1. scibot 23 Aug 2022
  
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  DOI: 10.1016/j.devcel.2022.07.012
  
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Inhibition of mutant IDH1 promotes cycling of acute myeloid leukemia stem cells

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CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder

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  DOI: 10.1016/j.cmet.2022.07.005
  
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IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage

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Intestinal inflammation alters the antigen-specific immune response to a skin commensal

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Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis

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Type 1 innate lymphoid cells regulate the onset of Toxoplasma gondii-induced neuroinflammation

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  DOI: 10.1016/j.celrep.2022.110564
  
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Bacterial infection disrupts established germinal center reactions through monocyte recruitment and impaired metabolic adaptation

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Brain Innate Immune Response via miRNA-TLR7 Sensing in Polymicrobial Sepsis

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Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections

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Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment

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Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo

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RORα is critical for mTORC1 activity in T cell-mediated colitis

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Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche

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  DOI: 10.1016/j.celrep.2021.109674
  
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Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration

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Gata2 heterozygous mutant mice exhibit reduced inflammatory responses and impaired bacterial clearance

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Untitled document

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Untitled document

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  DOI: 10.1016/j.immuni.2018.10.009
  
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A safe and effective mucosal RSV vaccine in mice consisting of RSV phosphoprotein and flagellin variant

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TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling

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  DOI: 10.1016/j.celrep.2021.109386
  
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Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells

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Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population

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Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy

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An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells

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MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism

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PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression

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Isolation of stromal vascular fraction cell suspensions from mouse and human adipose tissues for downstream applications

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Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells

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Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury

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Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells

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Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development

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Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity

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  Anti-mouse CD11b (M1/70)-APC-eFluor 780
  
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Restricted Hematopoietic Progenitors and Erythropoiesis Require SCF from Leptin Receptor+ Niche Cells in the Bone Marrow

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Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation

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  DOI: 10.1016/j.immuni.2019.06.009
  
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Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria

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  DOI: 10.1016/j.chom.2019.10.007
  
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Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss

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  DOI: 10.1016/j.cell.2019.12.002
  
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Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells

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  DOI: 10.1016/j.stem.2019.02.018
  
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  DOI: 10.1016/j.immuni.2019.01.009
  
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  DOI: 10.1016/j.celrep.2019.01.025
  
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Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2

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  DOI: 10.1016/j.celrep.2019.01.016
  
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  DOI: 10.1016/j.stem.2019.01.011
  
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  DOI: 10.1016/j.stem.2018.11.022
  
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Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis

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Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets

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Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis

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