Hypothesis

30 Matching Annotations

Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RNF20-mediated H2B monoubiquitination protects stalled forks from degradation and promotes fork restart

1
1. scibot 12 Aug 2025
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1038/s44319-025-00497-3
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12331980/
May 2025
www.sciencedirect.com www.sciencedirect.com

Genomic context influences translesion synthesis DNA polymerase-dependent mechanisms of micronuclei induction by G-quadruplexes

1
1. scibot 17 May 2025
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.celrep.2025.115706
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725004772
Aug 2024
www.sciencedirect.com www.sciencedirect.com

RTEL1 helicase counteracts RAD51-mediated homologous recombination and fork reversal to safeguard replicating genomes

1
1. scibot 20 Aug 2024
  
  in Public
  
  AB_1603759
  
  DOI: 10.1016/j.celrep.2024.114594
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724009239
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Small-Molecule Inhibition of CBX4/7 Hypersensitises Homologous Recombination-Impaired Cancer to Radiation by Compromising CtIP-Mediated DNA End Resection

1
1. scibot 15 Jun 2024
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.3390/cancers16112155
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11172190/
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein

1
1. scibot 27 Jul 2023
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.molcel.2023.06.031
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276523005075
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis

1
1. scibot 17 Jun 2023
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.molcel.2022.12.004
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7614657/
Nov 2022
www.sciencedirect.com www.sciencedirect.com

POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells

1
1. scibot 18 Nov 2022
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.celrep.2022.111716
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722015947
academic.oup.com academic.oup.com

Multiple-low-dose therapy: effective killing of high-grade serous ovarian cancer cells with ATR and CHK1 inhibitors

1
1. scibot 15 Nov 2022
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1093/narcan/zcac036
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

academic.oup.com/narcancer/article/4/4/zcac036/6825304
Jun 2022
www.sciencedirect.com www.sciencedirect.com

A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism

1
1. scibot 25 Jun 2022
  
  in Public
  
  AB_1603759
  
  DOI: 10.1016/j.isci.2022.104591
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S258900422200863X
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks

1
1. scibot 08 Apr 2022
  
  in Public
  
  RRID: AB_1603759
  
  DOI: 10.1016/j.isci.2022.104142
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004222004126
Feb 2022
www.sciencedirect.com www.sciencedirect.com

HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia

1
1. scibot 18 Feb 2022
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.molcel.2022.01.014
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276522000570
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sesquiterpene Lactones Potentiate Olaparib-Induced DNA Damage in p53 Wildtype Cancer Cells

1
1. scibot 16 Feb 2022
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.3390/ijms23031116
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8835362/
Nov 2021
www.sciencedirect.com www.sciencedirect.com

A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization

1
1. scibot 18 Nov 2021
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.molcel.2021.10.017
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276521009096
Oct 2021
link.springer.com link.springer.com

Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models

1
1. scibot 19 Oct 2021
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1186/s13046-021-02124-0
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

link.springer.com/article/10.1186/s13046-021-02124-0
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 29 Jul 2021
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.molcel.2018.10.036
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276518308967
www.sciencedirect.com www.sciencedirect.com

Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors

1
1. scibot 29 Jul 2021
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.molcel.2018.02.022
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276518301412
www.sciencedirect.com www.sciencedirect.com

EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart

1
1. scibot 03 Jul 2021
  
  in Public
  
  Ab79398
  
  DOI: 10.1016/j.molcel.2021.05.027
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_1603759
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276521004202
www.cell.com www.cell.com

Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency

1
1. scibot 03 Jul 2021
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.molcel.2021.06.011
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

cell.com/molecular-cell/fulltext/S1097-2765(21)00458-5
May 2021
www.sciencedirect.com www.sciencedirect.com

Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.molcel.2020.07.010
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276520304767
www.sciencedirect.com www.sciencedirect.com

Homology-directed repair protects the replicating genome from metabolic assaults

1
1. scibot 06 May 2021
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.devcel.2021.01.011
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580721000691
Mar 2021
www.sciencedirect.com www.sciencedirect.com

TRPS1 drives heterochromatic origin refiring and cancer genome evolution

1
1. scibot 10 Mar 2021
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.celrep.2021.108814
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721001285
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.celrep.2020.01.067
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720300929
www.sciencedirect.com www.sciencedirect.com

The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency

1
1. scibot 13 Sep 2020
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.celrep.2020.107985
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720309700
www.sciencedirect.com www.sciencedirect.com

The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells

1
1. scibot 09 Sep 2020
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.celrep.2020.107849
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_1603759
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720308305
Jan 2020
www.sciencedirect.com www.sciencedirect.com

RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.chembiol.2019.12.005
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945619304015
www.sciencedirect.com www.sciencedirect.com

ATR Signaling Uncouples the Role of RAD51 Paralogs in Homologous Recombination and Replication Stress Response

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.celrep.2019.09.008
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719311854
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.molcel.2018.11.036
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276518310062
www.sciencedirect.com www.sciencedirect.com

DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_1603759
  
  DOI: 10.1016/j.ccell.2019.02.004
  
  Resource: (Abcam Cat# ab79398, RRID:AB_1603759)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1603759
  
  What is this?
  
  RRID:AB_1603759 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819300996
Nov 2018
www.sciencedirect.com www.sciencedirect.com

BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_1603759
  
  Resource used:
  
  (Abcam Cat# ab79398, RRID:AB_1603759)
  
  SciCrunch record: RRID:AB_1603759
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_1603759
Visit annotations in context

Tags

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610818300199
Nov 2017
www.sciencedirect.com www.sciencedirect.com

RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_1603759
  
  Curator: @Zeljana_Babic
  
  Resource used:
  
  (Abcam Cat# ab79398, RRID:AB_1603759)
  
  SciCrunch record: RRID:AB_1603759
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_1603759 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_1603759

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276517302770