43 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Zinc finger protein 593 promotes breast cancer development by ensuring DNA damage repair and cell-cycle progression
    1
    1. scibot 17 Dec 2024
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      DOI: 10.1016/j.isci.2024.111513

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    sciencedirect.com/science/article/pii/S2589004224027408
  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    m6A-modified cenRNA stabilizes CENPA to ensure centromere integrity in cancer cells
    1
    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.040

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    sciencedirect.com/science/article/pii/S0092867424009693
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 Is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma
    1
    1. scibot 05 Sep 2024
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      DOI: 10.1158/1078-0432.CCR-23-3720

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    ncbi.nlm.nih.gov/pmc/articles/PMC11369621/
  6. Jul 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment of human cerebral organoid systems to model early neural development and assess the central neurotoxicity of environmental toxins
    1
    1. scibot 17 Jul 2024
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      DOI: 10.4103/NRR.NRR-D-23-00928

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    ncbi.nlm.nih.gov/pmc/articles/PMC11246146/
  8. Jun 2024
  9. www.sciencedirect.com www.sciencedirect.com
    LEUTX regulates porcine embryonic genome activation in somatic cell nuclear transfer embryos
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114372

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    sciencedirect.com/science/article/pii/S2211124724007009
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reversion from basal histone H4 hypoacetylation at the replication fork increases DNA damage in FANCA deficient cells
    1
    1. scibot 05 Jun 2024
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      DOI: 10.1371/journal.pone.0298032

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    ncbi.nlm.nih.gov/pmc/articles/PMC11142588/
  11. May 2024
  12. 52.53.155.43 52.53.155.43
    2024.02.25.581951v1.full-html.html
    1
    1. scibot 16 May 2024
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      DOI: 10.1038/nature12362

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    52.53.155.43/3cbbb6c4022cb0d94766603ef526c2fd13dcbc89/2024.02.25.581951v1.full-html.html
  13. Apr 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.celrep.2024.113924

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    ncbi.nlm.nih.gov/pmc/articles/PMC11025316/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Babaodan overcomes cisplatin resistance in cholangiocarcinoma via inhibiting YAP1
    1
    1. scibot 10 Apr 2024
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      DOI: 10.1080/13880209.2024.2331060

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    ncbi.nlm.nih.gov/pmc/articles/PMC10997361/
  16. Mar 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
    2
    1. scibot 21 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113924

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    2. scibot 21 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113924

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    ncbi.nlm.nih.gov/pmc/articles/PMC11025316/
  18. Feb 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycolysis Induced by METTL14 Is Essential for Macrophage Phagocytosis and Phenotype in Cervical Cancer
    1
    1. scibot 02 Feb 2024
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      DOI: 10.4049/jimmunol.2300339

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    ncbi.nlm.nih.gov/pmc/articles/PMC10828180/
  20. Jan 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TDP-43 chronic deficiency leads to dysregulation of transposable elements and gene expression by affecting R-loop and 5hmC crosstalk
    1
    1. scibot 09 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113662

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    ncbi.nlm.nih.gov/pmc/articles/PMC10857847/
  22. www.sciencedirect.com www.sciencedirect.com
    Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD
    1
    1. scibot 06 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.013

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    sciencedirect.com/science/article/pii/S1550413123004643
  23. Oct 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113270

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    sciencedirect.com/science/article/pii/S2211124723012822
  25. www.cell.com www.cell.com
    Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.isci.2023.108082

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    cell.com/iscience/abstract/S2589-0042(23)02159-4
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The biological effects of terahertz wave radiation-induced injury on neural stem cells
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.isci.2023.107418

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    ncbi.nlm.nih.gov/pmc/articles/PMC10523010/
  27. Aug 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ATR inhibitor VE-821 increases the sensitivity of gastric cancer cells to cisplatin
    1
    1. scibot 10 Aug 2023
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      DOI: 10.1016/j.tranon.2023.101743

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    ncbi.nlm.nih.gov/pmc/articles/PMC10400920/
  29. Jul 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Premature aging and reduced cancer incidence associated with near-complete body-wide Myc inactivation
    1
    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112830

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    sciencedirect.com/science/article/pii/S2211124723008410
  31. May 2023
  32. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Integrative transcriptomics and cell systems analyses reveal protective pathways controlled by Igfbp-3 in anthracycline-induced cardiotoxicity
    1
    1. scibot 24 May 2023
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      DOI: 10.1096/fj.202201885RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201885RR
  33. Feb 2023
  34. www.embopress.org www.embopress.org
    Unravelling homologous recombination repair deficiency and therapeutic opportunities in soft tissue and bone sarcoma
    1
    1. scibot 15 Feb 2023
      RRID:AB_1640564

      DOI: 10.15252/emmm.202216863

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    embopress.org/doi/10.15252/emmm.202216863
  35. www.mdpi.com www.mdpi.com
    Asparagine and Glutamine Deprivation Alters Ionizing Radiation Response, Migration and Adhesion of a p53null Colorectal Cancer Cell Line
    1
    1. scibot 08 Feb 2023
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      DOI: 10.3390/ijms24032983

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    mdpi.com/1422-0067/24/3/2983
  36. Dec 2022
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cystatin B deficiency results in sustained histone H3 tail cleavage in postnatal mouse brain mediated by increased chromatin-associated cathepsin L activity
    1
    1. scibot 16 Dec 2022
      RRID:AB_1640564

      DOI: 10.3389/fnmol.2022.1069122

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    ncbi.nlm.nih.gov/pmc/articles/PMC9749902/
  38. Oct 2022
  39. aacrjournals.org aacrjournals.org
    Selenium modulates cancer cell response to pharmacologic ascorbate
    1
    1. scibot 27 Oct 2022
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      DOI: 10.1158/0008-5472.CAN-22-0408

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    aacrjournals.org/cancerres/article/82/19/3486/709413/Selenium-Modulates-Cancer-Cell-Response-to
  40. Aug 2022
  41. www.sciencedirect.com www.sciencedirect.com
    SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis
    1
    1. scibot 17 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111233

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    sciencedirect.com/science/article/pii/S2211124722010506
  42. Jul 2022
  43. www.sciencedirect.com www.sciencedirect.com
    HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs
    1
    1. scibot 13 Jul 2022
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      DOI: 10.1016/j.celrep.2022.111038

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    sciencedirect.com/science/article/pii/S2211124722008324
  44. Dec 2021
  45. www.sciencedirect.com www.sciencedirect.com
    IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer
    1
    1. scibot 22 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110138

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    sciencedirect.com/science/article/pii/S221112472101634X
  46. Oct 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males
    1
    1. scibot 13 Oct 2021
      RRID:AB_1640564

      DOI: 10.1016/j.celrep.2021.109813

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    sciencedirect.com/science/article/pii/S2211124721012778
  48. Jul 2021
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 30 Jul 2021
      RRID:AB_1640564

      DOI: 10.1016/j.molcel.2018.08.020

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    ncbi.nlm.nih.gov/pmc/articles/PMC6202423/
  50. Jun 2021
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An Integrated Analysis of the Response of Colorectal Adenocarcinoma Caco-2 Cells to X-Ray Exposure
    1
    1. scibot 22 Jun 2021
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      DOI: 10.3389/fonc.2021.688919

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    ncbi.nlm.nih.gov/pmc/articles/PMC8209426/
  52. May 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Cas9 deactivation with photocleavable guide RNAs
    1
    1. scibot 08 May 2021
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      DOI: 10.1016/j.molcel.2021.02.007

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    sciencedirect.com/science/article/pii/S1097276521000939
  54. Apr 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: the polyG diseases
    1
    1. scibot 22 Apr 2021
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      DOI: 10.1016/j.neuron.2021.03.038

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    sciencedirect.com/science/article/pii/S0896627321002269
  56. Feb 2021
  57. www.sciencedirect.com www.sciencedirect.com
    A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia
    1
    1. scibot 28 Feb 2021
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      DOI: 10.1016/j.molcel.2020.11.040

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    sciencedirect.com/science/article/pii/S1097276520308406
  58. www.sciencedirect.com www.sciencedirect.com
    Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site
    1
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      DOI: 10.1016/j.ccell.2020.11.013

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    sciencedirect.com/science/article/pii/S153561082030605X
  59. Sep 2020
  60. www.sciencedirect.com www.sciencedirect.com
    The Mitochondrial Protein MAVS Stabilizes p53 to Suppress Tumorigenesis
    1
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      DOI: 10.1016/j.celrep.2019.12.051

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    sciencedirect.com/science/article/pii/S2211124719317085
  61. www.sciencedirect.com www.sciencedirect.com
    Cas12a Base Editors Induce Efficient and Specific Editing with Low DNA Damage Response
    1
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      DOI: 10.1016/j.celrep.2020.107723

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    sciencedirect.com/science/article/pii/S2211124720307002
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice
    1
    1. scibot 16 Sep 2020
      RRID:AB_1640564

      DOI: 10.7554/eLife.55828

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    ncbi.nlm.nih.gov/pmc/articles/PMC7324161/
  63. www.sciencedirect.com www.sciencedirect.com
    Systematic Characterization of Recurrent Genomic Alterations in Cyclin-Dependent Kinases Reveals Potential Therapeutic Strategies for Cancer Treatment
    1
    1. scibot 15 Sep 2020
      RRID:AB_1640564

      DOI: 10.1016/j.celrep.2020.107884

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    sciencedirect.com/science/article/pii/S2211124720308652
  64. Jan 2020
  65. elifesciences.org elifesciences.org
    Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria
    1
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      RRID:AB_1640564

      DOI: 10.7554/eLife.34836

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    elifesciences.org/articles/34836
  66. Nov 2018
  67. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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  68. europepmc.org europepmc.org
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  70. www.sciencedirect.com www.sciencedirect.com
    Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability
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