47 Matching Annotations
  1. Dec 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    H4K20me3-Mediated Repression of Inflammatory Genes is a Characteristic and Targetable Vulnerability of Persister Cancer Cells
    1
    1. scibot 13 Dec 2024
      RRID:AB_1642229

      DOI: 10.1158/0008-5472.CAN-24-0529

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    pmc.ncbi.nlm.nih.gov/articles/PMC7617193/
  3. Nov 2024
  4. 52.53.155.43 52.53.155.43
    can-24-0529-html.html
    1
    1. scibot 07 Nov 2024
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  5. May 2024
  6. 52.53.155.43 52.53.155.43
    2024.04.30.591961v1.full-html.html
    1
    1. scibot 09 May 2024
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      DOI: 10.1101/2024.04.30.591961

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  7. Mar 2024
  8. www.sciencedirect.com www.sciencedirect.com
    MOF-mediated acetylation of UHRF1 enhances UHRF1 E3 ligase activity to facilitate DNA methylation maintenance
    1
    1. scibot 06 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724002365
  9. Feb 2024
  10. 52.53.155.43 52.53.155.43
    The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells
    2
    1. scibot 22 Feb 2024
      RRID:AB_1642229

      DOI: 10.1152/ajpcell.00293.2023

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    2. scibot 22 Feb 2024
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      DOI: 10.1152/ajpcell.00293.2023

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    52.53.155.43/d532629e4f1cf755a6f5c302a21018f2c97350c4/reisbeck-et-al-2023-the-iron-chelator-and-oxphos-inhibitor-vlx600-induces-mitophagy-and-an-autophagy-dependent-type-of (1)-html.html
  11. journals.physiology.org journals.physiology.org
    The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells
    1
    1. scibot 16 Feb 2024
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      DOI: 10.1152/ajpcell.00293.2023

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    journals.physiology.org/doi/10.1152/ajpcell.00293.2023
  12. Dec 2023
  13. www.sciencedirect.com www.sciencedirect.com
    ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors
    1
    1. scibot 20 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113541

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    sciencedirect.com/science/article/pii/S221112472301553X
  14. Nov 2023
  15. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.ccell.2023.11.001

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    sciencedirect.com/science/article/pii/S1535610823003665
  16. Aug 2023
  17. 52.53.155.43 52.53.155.43
    MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC
    2
    1. scibot 17 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112939

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    2. scibot 11 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112939

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  18. Jul 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis
    1
    1. scibot 22 Jul 2023
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      DOI: 10.1016/j.cmet.2023.06.013

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    sciencedirect.com/science/article/pii/S1550413123002231
  20. Jun 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity
    1
    1. scibot 02 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.013

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    sciencedirect.com/science/article/pii/S0092867423005329
  22. May 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Methylated histones on mitotic chromosomes promote Topoisomerase IIα function for high fidelity chromosome segregation.
    1
    1. scibot 14 May 2023
      RRID:AB_1642229

      DOI: 10.1016/j.isci.2023.106743

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    sciencedirect.com/science/article/pii/S2589004223008209
  24. Mar 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer
    1
    1. scibot 16 Mar 2023
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      DOI: 10.1158/1078-0432.CCR-21-3603

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    ncbi.nlm.nih.gov/pmc/articles/PMC9481728/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mevalonate biosynthesis pathway regulates the development and survival of brown adipocytes
    1
    1. scibot 10 Mar 2023
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      DOI: 10.1016/j.isci.2023.106161

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    ncbi.nlm.nih.gov/pmc/articles/PMC9988578/
  27. Dec 2022
  28. www.sciencedirect.com www.sciencedirect.com
    Mechanisms of IRF2BPL-related disorders and identification of a potential therapeutic strategy
    1
    1. scibot 08 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111751

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    sciencedirect.com/science/article/pii/S2211124722016345
  29. aacrjournals.org aacrjournals.org
    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
    1
    1. scibot 03 Dec 2022
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      DOI: 10.1158/2159-8290.CD-21-1491

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    aacrjournals.org/cancerdiscovery/article/12/12/2880/711164/BAF-Complex-Maintains-Glioma-Stem-Cells-in
  30. Nov 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
    1
    1. scibot 24 Nov 2022
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      DOI: 10.1016/j.molcel.2022.11.002

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    sciencedirect.com/science/article/abs/pii/S1097276522010644
  32. www.sciencedirect.com www.sciencedirect.com
    Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
    1
    1. scibot 24 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111688

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    sciencedirect.com/science/article/pii/S2211124722015625
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    Cytoplasmic pool of U1 spliceosome protein SNRNP70 shapes the axonal transcriptome and regulates motor connectivity
    1
    1. scibot 17 Nov 2022
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      DOI: 10.1016/j.cub.2022.10.048

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    sciencedirect.com/science/article/pii/S0960982222016967
  34. Aug 2022
  35. www.sciencedirect.com www.sciencedirect.com
    CHAMP1 binds to REV7/FANCV and promotes homologous recombination repair
    1
    1. scibot 31 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111297

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    sciencedirect.com/science/article/pii/S2211124722011172
  36. 52.53.155.43 52.53.155.43
    ccr-21-3603-html.html
    1
    1. scibot 27 Aug 2022
      AB_1642229

      DOI: 10.1158/1078-0432.CCR-21-3603

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    52.53.155.43/de81104a0064110ab6f8eb2e443412de8e9dbc9e/ccr-21-3603-html.html
  37. Mar 2022
  38. academic.oup.com academic.oup.com
    Mst1/2 is necessary for satellite cell differentiation to promote muscle regeneration
    1
    1. scibot 02 Mar 2022
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      DOI: 10.1093/stmcls/sxab010

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    academic.oup.com/stmcls/advance-article/doi/10.1093/stmcls/sxab010/6511691
  39. Jan 2022
  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SKI-G-801, an AXL kinase inhibitor, blocks metastasis through inducing anti-tumor immune responses and potentiates anti-PD-1 therapy in mouse cancer models
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    1. scibot 05 Jan 2022
      3638

      DOI: 10.1002/cti2.1364

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    onlinelibrary.wiley.com/doi/10.1002/cti2.1364
  41. Aug 2021
  42. www.nature.com www.nature.com
    Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer
    1
    1. scibot 15 Aug 2021
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      DOI: 10.1038/s41467-021-24687-4

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    nature.com/articles/s41467-021-24687-4
  43. Jul 2021
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    1. scibot 28 Jul 2021
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      DOI: 10.1111/jnc.14144

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14144
  45. May 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
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    1. scibot 01 May 2021
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      DOI: 10.1016/j.cmet.2021.03.003

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    sciencedirect.com/science/article/pii/S1550413121001108
  47. Apr 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor
    1
    1. scibot 28 Apr 2021
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      DOI: 10.1016/j.chembiol.2021.04.004

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    sciencedirect.com/science/article/pii/S2451945621001598
  49. www.sciencedirect.com www.sciencedirect.com
    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
    1
    1. scibot 20 Apr 2021
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      DOI: 10.1016/j.ccell.2020.07.008

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    sciencedirect.com/science/article/pii/S153561082030369X
  50. Feb 2021
  51. academic.oup.com academic.oup.com
    Myeloid-derived Growth Factor Promotes Intestinal Glucagon-like Peptide-1 Production in Male Mice with Type 2 Diabetes
    1
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      DOI: 10.1210/endocr/bqaa003

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    academic.oup.com/endo/article/161/2/bqaa003/5698328
  52. Dec 2020
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation in amino-acid-poor environments is limited by tRNAGln charging
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    1. scibot 25 Dec 2020
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      DOI: 10.7554/eLife.62307

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    ncbi.nlm.nih.gov/pmc/articles/PMC7744096/
  54. Nov 2020
  55. www.sciencedirect.com www.sciencedirect.com
    G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program
    1
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      DOI: 10.1016/j.celrep.2020.108341

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    sciencedirect.com/science/article/pii/S2211124720313309
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    An epilepsy‐associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model
    2
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      DOI: 10.1002/jnr.24747

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      DOI: 10.1002/jnr.24747

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24747
  57. Sep 2020
  58. www.sciencedirect.com www.sciencedirect.com
    Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2
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      DOI: 10.1016/j.celrep.2020.02.007

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    sciencedirect.com/science/article/pii/S2211124720301613
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Direct Phosphorylation and Stabilization of MYC by Aurora B Kinase Promote T-cell Leukemogenesis
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    1. scibot 11 Sep 2020
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      DOI: 10.1016/j.ccell.2020.01.001

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    ncbi.nlm.nih.gov/pmc/articles/PMC7321798/
  60. www.sciencedirect.com www.sciencedirect.com
    Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage
    1
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      DOI: 10.1016/j.cell.2020.03.052

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    sciencedirect.com/science/article/pii/S0092867420303457
  61. Jan 2020
  62. www.sciencedirect.com www.sciencedirect.com
    PRC1 Catalytic Activity Is Central to Polycomb System Function
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      DOI: 10.1016/j.molcel.2019.12.001

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    sciencedirect.com/science/article/pii/S1097276519308925
  63. advances.sciencemag.org advances.sciencemag.org
    Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity
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    1. scibot 13 Jan 2020
      RRID:AB_1642229

      DOI: 10.1126/sciadv.aau7802

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    advances.sciencemag.org/content/5/9/eaau7802
  64. www.sciencedirect.com www.sciencedirect.com
    An RNA-Binding Protein Secreted by a Bacterial Pathogen Modulates RIG-I Signaling
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    1. scibot 13 Jan 2020
      RRID:AB_1642229

      DOI: 10.1016/j.chom.2019.10.004

      Resource: (Cell Signaling Technology Cat# 3638, RRID:AB_1642229)

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    sciencedirect.com/science/article/pii/S1931312819305281
  65. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_1642229

      DOI: 10.1016/j.molcel.2019.03.024

      Resource: (Cell Signaling Technology Cat# 3638, RRID:AB_1642229)

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    sciencedirect.com/science/article/pii/S109727651930228X
  66. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_1642229

      DOI: 10.1016/j.cell.2019.03.032

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    sciencedirect.com/science/article/pii/S0092867419303277
  67. www.sciencedirect.com www.sciencedirect.com
    MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis
    1
    1. scibot 12 Jan 2020
      RRID:AB_1642229

      DOI: 10.1016/j.molcel.2018.09.031

      Resource: (Cell Signaling Technology Cat# 3638, RRID:AB_1642229)

      Curator: @Jmenke

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      RRID:AB_1642229 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276518308025
  68. Nov 2018
  69. www.sciencedirect.com www.sciencedirect.com
    MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation
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    sciencedirect.com/science/article/pii/S1535610818302691
  70. www.sciencedirect.com www.sciencedirect.com
    EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation
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    1. scibot 05 Nov 2018
      RRID:AB_1642229

      Curator: @anp055

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    sciencedirect.com/science/article/pii/S1535610818302290
  71. Nov 2017
  72. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of histone deacetylase 1 or 2 reduces induced cytokine expression in microglia through a protein synthesis independent mechanism
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      RRID:AB_1642229

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14144/full