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CD40 agonism in renal cell carcinoma enhances immune checkpoint activity through myeloid cells

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1. scibot 30 Jun 2026
  
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  DOI: 10.1016/j.isci.2026.116527
  
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sciencedirect.com/science/article/pii/S2589004226019024
Jun 2026
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Type I interferon signaling in hematopoietic cells impairs neutrophil antibacterial function in the middle ear during viral co-infection

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1. scibot 04 Jun 2026
  
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  DOI: 10.1016/j.xcrm.2026.102846
  
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sciencedirect.com/science/article/pii/S2666379126002636
May 2026
www-cell-com.eproxy.lib.hku.hk www-cell-com.eproxy.lib.hku.hk

Whole-genome doubling drives immune evasion by silencing antigen presentation

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1. scibot 08 May 2026
  
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  DOI: 10.1016/j.ccell.2026.04.007
  
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www-cell-com.eproxy.lib.hku.hk/cancer-cell/fulltext/S1535-6108(26)00218-7
Apr 2026
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Lymphotoxin-beta receptor controls the development of chronic pain

1
1. scibot 23 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117269
  
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sciencedirect.com/science/article/pii/S2211124726003475
Feb 2026
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Sensory neurons drive immune exclusion by stimulating a dense extracellular matrix in the breast cancer tumor microenvironment

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  DOI: 10.1016/j.cell.2026.01.001
  
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sciencedirect.com/science/article/pii/S0092867426000486
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Meningeal blood vessel blockage enhances anti-glioblastoma immunity

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1. scibot 05 Feb 2026
  
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  DOI: 10.1016/j.cell.2025.12.045
  
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sciencedirect.com/science/article/pii/S0092867425014941
Jan 2026
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NF1 Loss Remodels Tumor Niches for Immune Evasion

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1. scibot 16 Jan 2026
  
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  DOI: 10.64898/2026.01.11.698818
  
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biorxiv.org/content/10.64898/2026.01.11.698818v1
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

DUSP11 is an intracellular innate immune checkpoint in lung adenocarcinoma

1
1. scibot 26 Nov 2025
  
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  DOI: 10.1158/2326-6066.CIR-25-0086
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12642826/
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1-s2.0-S2589004225022278-main-html.html

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1. scibot 13 Nov 2025
  
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  DOI: 10.1016/j.isci.2025.113966
  
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54.241.53.176/9d67ee9e0b95b1300362475325f611a208fd9da8/1-s2.0-S2589004225022278-main-html.html
Jul 2025
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Structure of gut microbial glycolipid modulates host inflammatory response

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1. scibot 23 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.05.016
  
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sciencedirect.com/science/article/pii/S0092867425005665
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Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma

1
1. scibot 16 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102239
  
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sciencedirect.com/science/article/pii/S266637912500312X
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The immune response against cancer is modulated by stromal cell fibronectin

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1. scibot 01 Jul 2025
  
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  DOI: 10.1016/j.neo.2025.101196
  
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sciencedirect.com/science/article/pii/S1476558625000764
Apr 2025
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Treatment of IL-18-binding protein biologics suppresses fibrotic progression in metabolic dysfunction-associated steatohepatitis

1
1. scibot 17 Apr 2025
  
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  DOI: 10.1016/j.xcrm.2025.102047
  
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sciencedirect.com/science/article/pii/S266637912500120X
Mar 2025
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Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity

1
1. scibot 27 Mar 2025
  
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  DOI: 10.1038/s41467-025-57684-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11929771/
Feb 2025
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A bladder-blood immune barrier constituted by suburothelial perivascular macrophages restrains uropathogen dissemination

1
1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.immuni.2025.02.002
  
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sciencedirect.com/science/article/pii/S107476132500069X
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Enhancing neutrophil cytotoxicity of a panel of clinical EGFR antibodies by Fc engineering to IgA3.0

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1. scibot 13 Feb 2025
  
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  RRID:AB_1659241
  
  DOI: 10.1158/1535-7163.MCT-24-0217
  
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aacrjournals.org/mct/article/23/9/1317/747340/Enhancing-Neutrophil-Cytotoxicity-of-a-Panel-of
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In vivo engineering of murine T cells using the evolved adeno-associated virus variant Ark313

1
1. scibot 06 Feb 2025
  
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  RRID:AB_1659241
  
  DOI: 10.1016/j.immuni.2025.01.009
  
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sciencedirect.com/science/article/pii/S1074761325000342
Dec 2024
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Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells

1
1. scibot 02 Dec 2024
  
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  RRID:AB_1659241
  
  DOI: 10.1016/j.celrep.2024.115023
  
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sciencedirect.com/science/article/pii/S2211124724013743
Sep 2024
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Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.celrep.2020.108677
  
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sciencedirect.com/science/article/pii/S2211124720316661
Aug 2024
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Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells

1
1. scibot 23 Aug 2024
  
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  DOI: 10.7554/eLife.76940
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
Jul 2024
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Primary nasal influenza infection rewires tissue-scale memory response dynamics

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.immuni.2024.06.005
  
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sciencedirect.com/science/article/pii/S107476132400311X
May 2024
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Distinct roles of TREM2 in central nervous system cancers and peripheral cancers

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1. scibot 24 May 2024
  
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  DOI: 10.1016/j.ccell.2024.05.001
  
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sciencedirect.com/science/article/pii/S1535610824001624
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Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy

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1. scibot 17 May 2024
  
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  DOI: 10.1016/j.ccell.2024.04.011
  
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sciencedirect.com/science/article/pii/S1535610824001351
Dec 2023
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Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma

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1. scibot 22 Dec 2023
  
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  DOI: 10.1016/j.cell.2023.11.032
  
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Machine learning analysis of the T cell receptor repertoire identifies sequence features of self-reactivity

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1. scibot 20 Dec 2023
  
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  RRID:AB_1659241
  
  DOI: 10.1016/j.cels.2023.11.004
  
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sciencedirect.com/science/article/pii/S2405471223003277
Nov 2023
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Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113447
  
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sciencedirect.com/science/article/pii/S2211124723014596
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CD115+ monocytes protect microbially experienced mice against E. coli-induced sepsis

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  DOI: 10.1016/j.celrep.2023.113345
  
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sciencedirect.com/science/article/pii/S2211124723013578
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Radial glia promote microglial development through integrin αVβ8 -TGFβ1 signaling

1
1. scibot 12 Oct 2023
  
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  DOI: 10.1101/2023.07.13.548459
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10542141/
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ß1-adrenergic blockers preserve neuromuscular function by inhibiting the production of extracellular traps during systemic inflammation in mice

1
1. scibot 12 Oct 2023
  
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  DOI: 10.3389/fimmu.2023.1228374
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10556451/
Sep 2023
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A transient wave of Bhlhe41+ resident macrophages enables remodeling of the developing infarcted myocardium

1
1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113174
  
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sciencedirect.com/science/article/pii/S2211124723011865
Aug 2023
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An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases

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1. scibot 26 Aug 2023
  
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  RRID:AB_1659241
  
  DOI: 10.1016/j.xcrm.2023.101130
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10439247/
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Original research: Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma

1
1. scibot 12 Aug 2023
  
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  RRID:AB_1659241
  
  DOI: 10.1136/jitc-2022-006457
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10414095/
Jul 2023
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Dendritic cell ICAM-1 strengthens synapses with CD8 T cells but is not required for their early differentiation

1
1. scibot 27 Jul 2023
  
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  RRID:AB_1659241
  
  DOI: 10.1016/j.celrep.2023.112864
  
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sciencedirect.com/science/article/pii/S2211124723008756
Jun 2023
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Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration

1
1. scibot 21 Jun 2023
  
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  RRID: 1659241
  
  DOI: 10.1016/j.celrep.2023.112647
  
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sciencedirect.com/science/article/pii/S2211124723006587
May 2023
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Age-dependent immune and lymphatic responses after spinal cord injury

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1. scibot 06 May 2023
  
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  RRID:AB_1659241
  
  DOI: 10.1016/j.neuron.2023.04.011
  
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sciencedirect.com/science/article/pii/S0896627323002969
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Original research: Targeting tumor vasculature to improve antitumor activity of T cells armed ex vivo with T cell engaging bispecific antibody

1
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  AB_1659241
  
  DOI: 10.1136/jitc-2023-006680
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10069597/
Mar 2023
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Original research: Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy

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  DOI: 10.1136/jitc-2022-006433
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10016286/
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Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy

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  DOI: 10.1126/sciimmunol.add8005
  
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science.org/doi/10.1126/sciimmunol.add8005
Feb 2023
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Renal control of life-threatening malarial anemia

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  DOI: 10.1016/j.celrep.2023.112057
  
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sciencedirect.com/science/article/pii/S2211124723000682
Jan 2023
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Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development

1
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  DOI: 10.1016/j.immuni.2022.11.013
  
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sciencedirect.com/science/article/pii/S1074761322006033
Aug 2022
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Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma

1
1. scibot 17 Aug 2022
  
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  DOI: 10.1016/j.immuni.2022.07.014
  
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sciencedirect.com/science/article/pii/S1074761322003491
Jun 2022
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Unravelling the sex-specific diversity and functions of adrenal gland macrophages

1
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  DOI: 10.1016/j.celrep.2022.110949
  
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Nt5e deficiency does not affect post-stroke inflammation and lesion size in a murine ischemia/reperfusion stroke model

1
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  DOI: 10.1016/j.isci.2022.104470
  
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sciencedirect.com/science/article/pii/S2589004222007416
May 2022
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Mitochondrial damage-associated molecular patterns trigger arginase-dependent lymphocyte immunoregulation

1
1. scibot 26 May 2022
  
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Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche

1
1. scibot 04 May 2022
  
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sciencedirect.com/science/article/pii/S1074761322001765
Dec 2021
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Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential

1
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Nov 2021
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COMMD10 is critical for Kupffer cell survival and controls Ly6Chi monocyte differentiation and inflammation in the injured liver

1
1. scibot 17 Nov 2021
  
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sciencedirect.com/science/article/pii/S2211124721015084
Sep 2021
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Modulating tumor infiltrating myeloid cells to enhance bispecific antibody-driven T cell infiltration and anti-tumor response

1
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  RRID:AB_1659241
  
  DOI: 10.1186/s13045-021-01156-5
  
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A subset of Kupffer cells regulates metabolism through the expression of CD36

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  DOI: 10.1016/j.immuni.2021.08.006
  
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IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer’s disease

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  DOI: 10.1016/j.celrep.2021.109574
  
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sciencedirect.com/science/article/pii/S2211124721010081
Aug 2021
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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

1
1. scibot 15 Aug 2021
  
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  DOI: 10.1016/j.ccell.2021.07.007
  
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sciencedirect.com/science/article/pii/S1535610821003846
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Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism

1
1. scibot 13 Aug 2021
  
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sciencedirect.com/science/article/pii/S2211124719303845
May 2021
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Inhibitory affinity modulation of FcγRIIA ligand binding by glycosphingolipids by inside-out signaling

1
1. scibot 19 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109142
  
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sciencedirect.com/science/article/pii/S2211124721004812
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Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis

1
1. scibot 06 May 2021
  
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  DOI: 10.1016/j.immuni.2020.06.003
  
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sciencedirect.com/science/article/pii/S1074761320302338
Apr 2021
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Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense

1
1. scibot 21 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.109012
  
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sciencedirect.com/science/article/pii/S2211124721003260
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Long-term evolution and short-term adaptation of microbiota strains and sub-strains in mice

1
1. scibot 19 Apr 2021
  
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  DOI: 10.1016/j.chom.2021.02.001
  
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sciencedirect.com/science/article/pii/S1931312821000470
Mar 2021
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Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy

1
1. scibot 09 Mar 2021
  
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  DOI: 10.1016/j.cell.2020.10.045
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7927154/
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Functional characterization of the dural sinuses as a neuroimmune interface

1
1. scibot 08 Mar 2021
  
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  DOI: 10.1016/j.cell.2020.12.040
  
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In vitro and ex vivo evaluation of tumor-derived exosome-induced dendritic cell dysfunction in mouse

1
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  DOI: 10.1016/j.xpro.2021.100361
  
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sciencedirect.com/science/article/pii/S266616672100068X
Feb 2021
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Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness

1
1. scibot 26 Feb 2021
  
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cell.com/immunity/abstract/S1074-7613(17)30190-5
Jan 2021
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Airway-Associated Macrophages in Homeostasis and Repair

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1. scibot 05 Jan 2021
  
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  DOI: 10.1016/j.celrep.2020.108553
  
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sciencedirect.com/science/article/pii/S2211124720315424
Nov 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes

1
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pubmed.ncbi.nlm.nih.gov/33147458/
Oct 2020
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PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction

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  DOI: 10.1016/j.celrep.2020.108278
  
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sciencedirect.com/science/article/pii/S2211124720312675
Sep 2020
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Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration

1
1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107796
  
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SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages

1
1. scibot 23 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.02.112
  
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Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies

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Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization

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The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis

1
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sciencedirect.com/science/article/pii/S2211124720302722
Jan 2020
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Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis

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  DOI: 10.1016/j.immuni.2019.06.010
  
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Targeting Degradation of the Transcription Factor C/EBPβ Reduces Lung Fibrosis by Restoring Activity of the Ubiquitin-Editing Enzyme A20 in Macrophages

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1659241
  
  DOI: 10.1016/j.immuni.2019.06.014
  
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  DOI: 10.1016/j.cmet.2019.05.002
  
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Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2

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  DOI: 10.1016/j.celrep.2019.01.016
  
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Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy

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Early Targeting of L-Selectin on Leukocytes Promotes Recovery after Spinal Cord Injury, Implicating Novel Mechanisms of Pathogenesis

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Identification of an Early Unipotent Neutrophil Progenitor with Pro-tumoral Activity in Mouse and Human Bone Marrow

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Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection

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Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes

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Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility

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Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain

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Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness

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Long-term intravital imaging of the multicolor-coded tumor microenvironment during combination immunotherapy

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