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Fatty acid uptake mediated by FABP4 promotes the formation of CD8+T cell senescence through lipid peroxidation in the adipocyte-rich microenvironment of Ovarian Cancer

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Jan 2026
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Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer

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sciencedirect.com/science/article/pii/S266637912500607X
Dec 2025
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Positioning and reversible suppression of CCR7+ dendritic cells in perivascular tumor niches shape cancer immunity

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Aberrant hypothalamic neuronal activity blunts glucocorticoid diurnal rhythms in murine breast cancer

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Oct 2025
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TET2-mutant clonal hematopoiesis enhances macrophage antigen presentation and improves immune checkpoint therapy in solid tumors

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Spliceosome inhibition induces Z-RNA and ZBP1-driven cell death in small cell lung cancer

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Endogenous CD4+ T cells that recognize ALK and the NPM1::ALK fusion protein can be expanded from human peripheral blood

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Jul 2025
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A fluorescent STING ligand sensor for high-throughput screening of compounds that can enhance tumor immunotherapy

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sciencedirect.com/science/article/pii/S2667237525001420
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Sca-1 expression depicts pro-inflammatory murine neutrophils under steady-state and pathological conditions

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Jun 2025
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Bile acids activate cancer-associated fibroblasts and induce an immunosuppressive microenvironment in cholangiocarcinoma

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May 2025
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Overcoming NK-mediated rejection by anti-3rd-party central memory veto CD8 T cells through downregulation of DNAM-1 on alloreactive NK cells

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1. scibot 16 May 2025
  
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Bone metastases diminish extraosseous response to checkpoint blockade immunotherapy through osteopontin-producing osteoclasts

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Apr 2025
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Treatment of IL-18-binding protein biologics suppresses fibrotic progression in metabolic dysfunction-associated steatohepatitis

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An erythroid-biased FOShi hematopoietic multipotent progenitor subpopulation contributes to adaptation to chronic hypoxia

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Sex differences in DNMT3A-mutant clonal hematopoiesis and the effects of estrogen

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An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis

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Mar 2025
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Targeting tumor monocyte-intrinsic PD-L1 by rewiring STING signaling and enhancing STING agonist therapy

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1. scibot 11 Mar 2025
  
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Feb 2025
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Selective apoptosis of tumor-associated platelets boosts the anti-metastatic potency of PD-1 blockade therapy

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1. scibot 28 Feb 2025
  
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An oral tricyclic STING agonist suppresses tumor growth through remodeling of the immune microenvironment

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Jan 2025
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Splenic fibroblasts control marginal zone B cell movement and function via two distinct Notch2-dependent regulatory programs

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Dec 2024
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Targeting P4HA1 promotes CD8+ T cell progenitor expansion toward immune memory and systemic anti-tumor immunity

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cell.com/cancer-cell/abstract/S1535-6108(24)00476-8
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Staphylococcus aureus induced trained immunity in macrophages confers heterologous protection against gram-negative bacterial infection

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Vimentin modulates regulatory T cell receptor-ligand interactions at distal pole complex, leading to dysregulated host response to viral pneumonia

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Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer

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Voluntary exercise sensitizes cancer immunotherapy via the collagen inhibition-orchestrated inflammatory tumor immune microenvironment

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Aug 2024
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Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity

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The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance

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science.org/doi/10.1126/sciimmunol.abb6032
May 2024
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CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+ T cells in diabetic autoimmunity

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Mar 2024
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Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions

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Feb 2024
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Inflammatory dendritic cells restrain CD11b+CD4+ CTLs via CD200R in human NSCLC

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Jan 2024
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Tumor cell–intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling

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  DOI: 10.1126/sciadv.adi2012
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10798567/
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Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death

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  DOI: 10.1016/j.cell.2023.12.015
  
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sciencedirect.com/science/article/pii/S0092867423013478
Dec 2023
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Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms

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  DOI: 10.1016/j.xcrm.2023.101245
  
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Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing

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Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer

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CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance

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Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity

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Molecular mechanisms of snoRNA-IL-15 crosstalk in adipocyte lipolysis and NK cell rejuvenation

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The T-cell-directed vaccine BNT162b4 encoding conserved non-spike antigens protects animals from severe SARS-CoV-2 infection

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Helicobacter spp. are prevalent in wild mice and protect from lethal Citrobacter rodentium infection in the absence of adaptive immunity

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Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy

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The ion channel CALHM6 controls bacterial infection-induced cellular cross-talk at the immunological synapse

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Zika virus spreads through infection of lymph node-resident macrophages

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TNFR2+ regulatory T cells protect against bacteremic pneumococcal pneumonia by suppressing IL-17A-producing γδ T cells in the lung

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Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses

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Phospholipid metabolites of the gut microbiota promote hypoxia-induced intestinal injury via CD1d-dependent γδ T cells

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Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence

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Poroptosis: a form of cell death depending on plasma membrane nanopores formation

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Resurfaced ZIKV EDIII nanoparticle immunogens elicit neutralizing and protective responses in vivo

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BPS Publications

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Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade

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Protocol for analyzing and visualizing antiviral immune responses after acute infection of the murine oral mucosa

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Natural Tr1-like cells do not confer long-term tolerogenic memory

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  Rat monoclonal CD3 (clone 17A2)
  
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Transcriptional profiling of breast cancer‐associated lymphatic vessels reveals VCAM‐1 as regulator of lymphatic invasion and permeability

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  CD3‐PE/Cy7
  
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Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium

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Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis

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Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging

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Mechanical Stiffness Controls Dendritic Cell Metabolism and Function

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A Thermostable mRNA Vaccine against COVID-19

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Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms

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GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance

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Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation

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HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma

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Untitled document

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Untitled document

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Untitled document

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Untitled document

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Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy

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  RRID:AB_1732057
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6775781/
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Untitled document

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1. scibot 05 Nov 2018
  
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  RRID:AB_1732057
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5714502/
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Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis

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1. scibot 05 Nov 2018
  
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  RRID:AB_1732057
  
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  (BioLegend Cat# 100220, RRID:AB_1732057)
  
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  RRID:AB_1732057
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sciencedirect.com/science/article/pii/S1074761317304727

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