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Nov 2025
www.science.org www.science.org

Single coadministration of erythrocyte-uricase conjugate and immunosuppressant induces durable immune tolerance for gout therapy

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  DOI: 10.1126/sciadv.aea5196
  
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science.org/doi/10.1126/sciadv.aea5196
Sep 2025
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Red Blood Cell-Mediated Enhancement of Hematopoietic Stem Cell Functions via a Hes1-Dependent Pathway

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  DOI: 10.1096/fj.202500885R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202500885R
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CD226 identifies effector CD8+ T cells during tuberculosis and costimulates recognition of Mycobacterium tuberculosis-infected macrophages

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sciencedirect.com/science/article/pii/S2211124725009556
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Immune targeting of triple-negative breast cancer through a clinically actionable STING agonist-CAR T cell platform

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pmc.ncbi.nlm.nih.gov/articles/PMC12281382/
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Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade

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sciencedirect.com/science/article/pii/S2666379125002149
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pharmacological rescue of mutant p53 triggers spontaneous tumor regression via immune responses

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pmc.ncbi.nlm.nih.gov/articles/PMC11970324/
Dec 2024
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Vimentin modulates regulatory T cell receptor-ligand interactions at distal pole complex, leading to dysregulated host response to viral pneumonia

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sciencedirect.com/science/article/pii/S2211124724014074
Sep 2024
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Protocol for assessing murine cell doublet engagement and subsequent effects using flow cytometry and imaging flow cytometry

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sciencedirect.com/science/article/pii/S2666166724003174
Jul 2024
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Kmt2c restricts G-CSF-driven HSC mobilization and granulocyte production in a methyltransferase-independent manner

2
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sciencedirect.com/science/article/pii/S2211124724008714
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Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer

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1. scibot 18 Jul 2024
  
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cell.com/cancer-cell/abstract/S1535-6108(24)00226-5
Jun 2024
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Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity

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sciencedirect.com/science/article/pii/S2211124724006284
May 2024
52.53.155.43 52.53.155.43

Hypomethylation-enhanced CRTC2 expression drives malignant phenotypes and primary resistance to immunotherapy in hepatocellular carcinoma

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1. scibot 02 May 2024
  
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  DOI: 10.1016/j.isci.2024.109821
  
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52.53.155.43/90443b9a27af60bb323bc92daf2d7421a807e517/PIIS2589004224010435-html.html
Apr 2024
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The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia

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sciencedirect.com/science/article/pii/S1535610824000941
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

FcγRIIB is an immune checkpoint limiting the activity of Treg-targeting antibodies in the tumor microenvironment

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1. scibot 06 Mar 2024
  
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  DOI: 10.1158/2326-6066.CIR-23-0389
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10911703/
Feb 2024
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Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma

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1. scibot 21 Feb 2024
  
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  DOI: 10.1016/j.xcrm.2024.101415
  
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  DOI: 10.1016/j.xcrm.2024.101415
  
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sciencedirect.com/science/article/pii/S2666379124000387
Jan 2024
52.53.155.43 52.53.155.43

Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors

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1. scibot 10 Jan 2024
  
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  DOI: 10.1126/sciimmunol.abq2424
  
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52.53.155.43/93ebbe5a83b6a28b0d01edad42fa81f437079176/sciimmunol.abq2424_sm-html.html
Dec 2023
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Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth

1
1. scibot 22 Dec 2023
  
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  DOI: 10.1016/j.cmet.2023.11.013
  
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sciencedirect.com/science/article/pii/S155041312300445X
www.mdpi.com www.mdpi.com

Ascomylactam C Induces an Immunogenic Cell Death Signature via Mitochondria-Associated ER Stress in Lung Cancer and Melanoma

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1. scibot 01 Dec 2023
  
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  DOI: 10.3390/md21120600
  
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mdpi.com/1660-3397/21/12/600
Nov 2023
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FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation

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1. scibot 17 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113362
  
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sciencedirect.com/science/article/pii/S2211124723013748
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Virus-induced lncRNA-BTX allows viral replication by regulating intracellular translocation of DHX9 and ILF3 to induce innate escape

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sciencedirect.com/science/article/pii/S2211124723012743
Jul 2023
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Differential effects of sugar and fat on adipose tissue inflammation

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  DOI: 10.1016/j.isci.2023.107163
  
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sciencedirect.com/science/article/pii/S2589004223012403
Apr 2023
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SIRT2 inhibition by AGK2 enhances mycobacteria-specific stem cell memory responses by modulating beta-catenin and glycolysis

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1. scibot 27 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106644
  
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sciencedirect.com/science/article/pii/S2589004223007216
Mar 2023
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Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma

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  DOI: 10.1016/j.celrep.2023.112197
  
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sciencedirect.com/science/article/pii/S2211124723002085
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Phosphoenolpyruvate regulates the Th17 transcriptional program and inhibits autoimmunity

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  DOI: 10.1016/j.celrep.2023.112205
  
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sciencedirect.com/science/article/pii/S2211124723002164
Jan 2023
52.53.155.43 52.53.155.43

SSRN-id4265019-html.html

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  DOI: 10.2139/ssrn.4265019
  
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52.53.155.43/7fa70c9c4ef484c26f104e85bcdc5ead50c41c8f/SSRN-id4265019-html.html
Nov 2022
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Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer

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  DOI: 10.1016/j.celrep.2022.111596
  
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sciencedirect.com/science/article/pii/S2211124722014619
Oct 2022
52.53.155.43 52.53.155.43

IgA deficiency destabilizes immunological homeostasis towards intestinal microbiota and increases the risk of systemic immune dysregulation

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1. scibot 27 Oct 2022
  
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  DOI: 10.1101/2021.08.20.21261620
  
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52.53.155.43/62b31cea1ac090bac2ebe32e4dfd3474fee27f84/2021.08.20.21261620v1.full-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mouse phospholipid phosphatase 6 regulates dendritic cell cholesterol, macropinocytosis, and allergen sensitization

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  DOI: 10.1016/j.isci.2022.105185
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9550614/
Sep 2022
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In vivo bioluminescence imaging of granzyme B activity in tumor response to cancer immunotherapy

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  DOI: 10.1016/j.chembiol.2022.08.006
  
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sciencedirect.com/science/article/pii/S2451945622003142
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Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance

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1. scibot 11 Sep 2022
  
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  DOI: 10.1016/j.ccell.2022.08.012
  
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sciencedirect.com/science/article/pii/S1535610822003762
Aug 2022
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Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway

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1. scibot 06 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111158
  
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sciencedirect.com/science/article/pii/S2211124722009676
Nov 2021
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Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease

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1. scibot 03 Nov 2021
  
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  DOI: 10.1016/j.cmet.2021.10.010
  
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sciencedirect.com/science/article/pii/S1550413121004885
Sep 2021
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Live Imaging of SARS-CoV-2 Infection in Mice Reveals that Neutralizing Antibodies Require Fc Function for Optimal Efficacy

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1. scibot 23 Sep 2021
  
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  DOI: 10.1016/j.immuni.2021.08.015
  
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A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism

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  DOI: 10.1016/j.celrep.2021.109748
  
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Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma

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  DOI: 10.1016/j.xcrm.2021.100399
  
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Jul 2021
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A Comprehensive Roadmap of Murine Spermatogenesis Defined by Single-Cell RNA-Seq

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1. scibot 30 Jul 2021
  
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  DOI: 10.1016/j.devcel.2018.07.025
  
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CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling

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1. scibot 24 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.06.021
  
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Mar 2021
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In vitro and ex vivo evaluation of tumor-derived exosome-induced dendritic cell dysfunction in mouse

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1. scibot 06 Mar 2021
  
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  DOI: 10.1016/j.xpro.2021.100361
  
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Feb 2021
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Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy

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1. scibot 24 Feb 2021
  
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  DOI: 10.1016/j.celrep.2021.108751
  
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Sep 2020
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Resolving Cell Cycle Speed in One Snapshot with a Live-Cell Fluorescent Reporter

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1. scibot 23 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107804
  
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Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling

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  DOI: 10.1016/j.celrep.2020.02.028
  
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Jan 2020
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The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair

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  DOI: 10.1016/j.immuni.2019.06.005
  
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Nov 2018
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A Comprehensive Roadmap of Murine Spermatogenesis Defined by Single-Cell RNA-Seq

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Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop

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