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MHC-II-restricted neoantigen vaccine reverses immune microenvironment and overcomes resistance to immune-checkpoint inhibitors in cold tumors

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.medj.2025.100936
  
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sciencedirect.com:5037/science/article/pii/S2666634025003630
Jul 2025
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.001
  
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sciencedirect.com/science/article/pii/S1074761325002481
Jun 2025
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Diet-derived LPS determines intestinal IgA induction and repertoire characteristics independently of the microbiota

1
1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.024
  
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sciencedirect.com/science/article/pii/S1074761325002456
May 2025
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Cancer vaccine from intracellularly gelated tumor cells functionalized with CD47 blockage and damage-associated molecular pattern exposure

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1. scibot 19 May 2025
  
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  DOI: 10.1016/j.xcrm.2025.102092
  
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sciencedirect.com/science/article/pii/S266637912500165X
Apr 2025
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Immunological analysis of LC16m8 vaccine: preclinical and early clinical insights into mpox

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1. scibot 17 Apr 2025
  
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  DOI: 10.1016/j.ebiom.2025.105703
  
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sciencedirect.com/science/article/pii/S2352396425001471
Mar 2025
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Lung-resident memory B cells maintain allergic IgE responses in the respiratory tract

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.03.001
  
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sciencedirect.com/science/article/pii/S1074761325000950
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BET inhibitor in combination with BCG vaccine enhances antitumor efficacy and orchestrates T cell reprogramming for melanoma

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.101995
  
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sciencedirect.com/science/article/pii/S2666379125000680
Feb 2025
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AKR1D1 suppresses liver cancer progression by promoting bile acid metabolism-mediated NK cell cytotoxicity

1
1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.011
  
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sciencedirect.com/science/article/pii/S1550413125000117
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Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer

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1. scibot 13 Feb 2025
  
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  DOI: 10.1126/scitranslmed.adj9366
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11811823/
Dec 2024
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IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages

1
1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115039
  
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sciencedirect.com/science/article/pii/S2211124724013901
Sep 2024
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The transcription regulator ID3 maintains tumor-specific memory CD8+ T cells in draining lymph nodes during tumorigenesis

1
1. scibot 04 Sep 2024
  
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  AB_1877231
  
  DOI: 10.1016/j.celrep.2024.114690
  
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sciencedirect.com/science/article/pii/S2211124724010416
Aug 2024
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Indirect suppression of CD4 T cell activation through LAG-3-mediated trans-endocytosis of MHC class II

1
1. scibot 27 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114655
  
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sciencedirect.com/science/article/pii/S2211124724010064
Jul 2024
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Neuronal-enriched small extracellular vesicles trigger a PD-L1-mediated broad suppression of T cells in Parkinson’s disease

1
1. scibot 10 Jul 2024
  
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  RRID:AB_1877231
  
  DOI: 10.1016/j.isci.2024.110243
  
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sciencedirect.com/science/article/pii/S2589004224014688
Jun 2024
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A single infusion of engineered long-lived and multifunctional T cells confers durable remission of asthma in mice

1
1. scibot 06 Jun 2024
  
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  RRID:AB_1877231
  
  DOI: 10.1038/s41590-024-01834-9
  
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nature.com/articles/s41590-024-01834-9
May 2024
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Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor

1
1. scibot 14 May 2024
  
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  RRID:AB_1877231
  
  DOI: 10.1016/j.cell.2024.04.023
  
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sciencedirect.com/science/article/pii/S0092867424004483
Mar 2024
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Protocol to assess bioenergetics and mitochondrial fuel usage in murine autoreactive immunocytes using the Seahorse Extracellular Flux Analyzer

1
1. scibot 29 Mar 2024
  
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  RRID:AB_1877231
  
  DOI: 10.1016/j.xpro.2024.102971
  
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sciencedirect.com/science/article/pii/S2666166724001369
52.53.155.43 52.53.155.43

Low-dose Decitabine enhances the efficacy of viral cancer vaccines for immunotherapy.

1
1. scibot 12 Mar 2024
  
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  RRID:AB_1877231
  
  DOI: 10.1016/j.omton.2024.200766
  
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52.53.155.43/8c6eb3b4d009a4f511a3160975bf106d9641ff9c/1-s2.0-S2950329924000080-main-html.html
Jan 2024
52.53.155.43 52.53.155.43

Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors

1
1. scibot 10 Jan 2024
  
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  RRID:AB_1877231
  
  DOI: 10.1126/sciimmunol.abq2424
  
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52.53.155.43/93ebbe5a83b6a28b0d01edad42fa81f437079176/sciimmunol.abq2424_sm-html.html
Nov 2023
www.biorxiv.org www.biorxiv.org

One infusion of engineered long-lasting and multifunctional T cells cures asthma in mice

1
1. scibot 17 Nov 2023
  
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  RRID:AB_1877231
  
  DOI: 10.1101/2023.11.06.565713
  
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biorxiv.org/content/10.1101/2023.11.06.565713v1
Oct 2023
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The Transcription Factor IRF4 Determines the Anti-Tumor Immunity of CD8+ T cells

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.108087
  
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cell.com/iscience/abstract/S2589-0042(23)02164-8
Jun 2023
52.53.155.43 52.53.155.43

TOPK mediates immune evasion of Renal Cell Carcinoma via upregulating the expression of PD-L1

1
1. scibot 30 Jun 2023
  
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  DOI: 10.1016/j.isci.2023.107185
  
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52.53.155.43/9a5455060dac46a2102bae7baf607274e71beaee/1-s2.0-S2589004223012622-main-html.html
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MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma

1
1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.ccell.2023.05.015
  
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sciencedirect.com/science/article/pii/S1535610823001824
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Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters

1
1. scibot 08 Jun 2023
  
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  DOI: 10.1038/s41467-023-38512-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10244369/
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Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer

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1. scibot 03 Jun 2023
  
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  DOI: 10.1016/j.isci.2023.106916
  
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sciencedirect.com/science/article/pii/S2589004223009938
May 2023
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STAT3 signaling in B cells controls germinal center zone organization and recycling

1
1. scibot 18 May 2023
  
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  RRID:AB_1877231
  
  DOI: 10.1016/j.celrep.2023.112512
  
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sciencedirect.com/science/article/pii/S2211124723005235
Apr 2023
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An optimized IL-12-Fc expands its therapeutic window, achieving strong activity against mouse tumors at tolerable drug doses

1
1. scibot 14 Apr 2023
  
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  DOI: 10.1016/j.medj.2023.03.007
  
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sciencedirect.com/science/article/pii/S2666634023001034
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Spleen fibroblastic reticular cell-derived acetylcholine promotes lipid metabolism to drive autoreactive B cell responses

1
1. scibot 06 Apr 2023
  
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  DOI: 10.1016/j.cmet.2023.03.010
  
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sciencedirect.com/science/article/pii/S1550413123000888
Mar 2023
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Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment

1
1. scibot 16 Mar 2023
  
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  DOI: 10.1016/j.ccell.2023.02.005
  
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sciencedirect.com/science/article/pii/S1535610823000338
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Controlled release of enhanced cross-hybrid IgGA Fc PD-L1 inhibitors using oncolytic adenoviruses

1
1. scibot 16 Mar 2023
  
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  RRID:AB_1877231
  
  DOI: 10.1016/j.omto.2023.01.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9995465/
Feb 2023
www.embopress.org www.embopress.org

Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer

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1. scibot 23 Feb 2023
  
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  RRID:AB_1877231
  
  DOI: 10.15252/embr.202256524
  
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embopress.org/doi/10.15252/embr.202256524
Jan 2023
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Protocol to assess the antitumor efficacy of an immunotherapeutic peptide in syngeneic orthotopic glioma mouse models

1
1. scibot 21 Jan 2023
  
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  RRID:AB_1877231
  
  DOI: 10.1016/j.xpro.2023.102049
  
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sciencedirect.com/science/article/pii/S2666166723000072
Nov 2022
www.researchsquare.com www.researchsquare.com

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1. scibot 11 Nov 2022
  
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  RRID:AB_1877231
  
  DOI: 10.21203/rs.3.rs-658360/v1
  
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researchsquare.com/article/rs-7072571/'https://www.researchsquare.com/article/rs-7072571/v1
Feb 2022
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SARS-CoV-2 variants of concern display enhanced intrinsic pathogenic properties and expanded organ tropism in mouse models

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1. scibot 11 Feb 2022
  
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  DOI: 10.1016/j.celrep.2022.110387
  
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2. scibot 09 Feb 2022
  
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  DOI: 10.1016/j.celrep.2022.110387
  
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sciencedirect.com/science/article/pii/S2211124722001085
Dec 2021
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Genome-wide fitness gene identification reveals Roquin as a potent suppressor of CD8 T cell expansion and anti-tumor immunity

1
1. scibot 08 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110083
  
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Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity

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  RRID:AB_1877231
  
  DOI: 10.1016/j.immuni.2021.11.004
  
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Novel oncolytic adenovirus expressing enhanced cross-hybrid IgGA Fc PD-L1 inhibitor activates multiple immune effector populations leading to enhanced tumor killing in vitro, in vivo and with patient-derived tumor organoids

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1. scibot 16 Aug 2021
  
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  DOI: 10.1136/jitc-2021-003000
  
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Jul 2021
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The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis

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1. scibot 28 Jul 2021
  
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  PD-1 PE (clone 29F.1A12)
  
  DOI: 10.1016/j.immuni.2019.05.022
  
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Untitled document

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  DOI: 10.1016/j.immuni.2018.10.012
  
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Jun 2021
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A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens

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1. scibot 26 Jun 2021
  
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  DOI: 10.1016/j.isci.2021.102699
  
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Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

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1. scibot 25 Jun 2021
  
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  DOI: 10.1016/j.cell.2021.05.038
  
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NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion

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1. scibot 30 Apr 2021
  
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  RRID:AB_1877231
  
  DOI: 10.1016/j.cmet.2020.10.021
  
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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

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  DOI: 10.1016/j.immuni.2021.03.007
  
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Jan 2020
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Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cell.2019.07.044
  
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Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.07.065
  
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Nov 2018
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Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors

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Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation

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1. scibot 05 Nov 2018
  
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Small Interfering RNA-Mediated Control of Virus Replication in the CNS Is Therapeutic and Enables Natural Immunity to West Nile Virus

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1. scibot 05 Nov 2018
  
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