43 Matching Annotations
  1. Last 7 days
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    Cyclin-dependent kinase-9 and oxidative phosphorylation inhibition overcome ibrutinib resistance in mantle cell lymphoma
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    aacrjournals.org/cancerrescommun/article/6/5/1192/785363/Cyclin-Dependent-Kinase-9-and-Oxidative
  3. Jun 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SETD2 Deficiency Drives Mitochondrial DNA Leakage and Creates a Druggable Dependency on BCL-xL in Clear Cell Renal Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13244386/
  5. Apr 2026
  6. www.jci.org www.jci.org
    Combinatorial therapy regimens targeting preclinical models of melanoma resistant to immune checkpoint blockade
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    jci.org/articles/view/185220
  7. Dec 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defining the antitumor mechanism of action of a clinical-stage compound as a selective degrader of the nuclear pore complex
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    pmc.ncbi.nlm.nih.gov/articles/PMC12670082/
  9. Jul 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the WSB2–NOXA axis in cancer cells for enhanced sensitivity to BCL-2 family protein inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12286604/
  11. Apr 2025
  12. www.sciencedirect.com www.sciencedirect.com
    Downregulation of rRNA synthesis by BCL-2 induces chemoresistance in diffuse large B cell lymphoma
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    sciencedirect.com/science/article/pii/S2589004225005942
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964295/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Xuebijing injection alleviates septic acute kidney injury by modulating inflammation, mitochondrial dysfunction, and endoplasmic reticulum stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC11951319/
  15. Feb 2025
  16. 52.53.155.43 52.53.155.43
    PDF-html.html
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  17. Dec 2024
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    GW117 induces anxiolytic effects by improving hippocampal functions
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    sciencedirect.com/science/article/pii/S0091305724002211
  19. Oct 2024
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    Leucine restriction ameliorates Fusobacterium nucleatum-driven malignant progression and radioresistance in nasopharyngeal carcinoma
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    sciencedirect.com/science/article/pii/S266637912400483X
  21. Sep 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11372365/
  23. May 2024
  24. www.sciencedirect.com www.sciencedirect.com
    Venetoclax acts as an immunometabolic modulator to potentiate adoptive NK cell immunotherapy against leukemia
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    sciencedirect.com/science/article/pii/S2666379124002726
  25. Mar 2024
  26. www.nature.com www.nature.com
    Light-mediated intracellular polymerization
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    nature.com/articles/s41596-024-00970-8
  27. Nov 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10629731/
  29. Oct 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Breast Cancer Cells are Sensitized by Piperine to Radiotherapy through Estrogen Receptor-α mediated modulation of a Key NHEJ repair protein- DNA-PK
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    sciencedirect.com/science/article/pii/S0944711323004865
  31. Jun 2023
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10236151/
  33. May 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9633392/
  35. Sep 2022
  36. www.sciencedirect.com www.sciencedirect.com
    BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer
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    sciencedirect.com/science/article/pii/S2211124722011287
  37. Jun 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A
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    ncbi.nlm.nih.gov/pmc/articles/PMC9218363/
  39. Apr 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage
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    sciencedirect.com/science/article/pii/S1534580722002295
  41. Jan 2022
  42. www.sciencedirect.com www.sciencedirect.com
    AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia
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    sciencedirect.com/science/article/pii/S2211124721017010
  43. Dec 2021
  44. mct.aacrjournals.org mct.aacrjournals.org
    Antibody-drug conjugate efficacy in neuroblastoma - role of payload, resistance mechanisms, target density, and antibody internalization
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    mct.aacrjournals.org/content/20/11/2228
  45. Nov 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Interplay between protein acetylation and ubiquitination controls MCL1 protein stability
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    sciencedirect.com/science/article/pii/S2211124721014674
  47. Aug 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity
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    sciencedirect.com/science/article/pii/S1550413119300117
  49. www.sciencedirect.com www.sciencedirect.com
    ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma
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    sciencedirect.com/science/article/pii/S221112472100872X
  50. Jul 2021
  51. academic.oup.com academic.oup.com
    Untitled document
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    academic.oup.com/endo/article/157/11/4487/2758428
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    Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity
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    sciencedirect.com/science/article/pii/S1550413119300117
  53. www.sciencedirect.com www.sciencedirect.com
    Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target
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    sciencedirect.com/science/article/pii/S1357272521001060
  54. May 2021
  55. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15435
  56. Nov 2020
  57. www.authorea.com www.authorea.com
    Natural Product Trienomycin A is a STAT3 pathway inhibitor that exhibits potent in vitro and in vivo efficacy against pancreatic cancer
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    authorea.com/users/368637/articles/487712-natural-product-trienomycin-a-is-a-stat3-pathway-inhibitor-that-exhibits-potent-in-vitro-and-in-vivo-efficacy-against-pancreatic-cancer
  58. Sep 2020
  59. www.sciencedirect.com www.sciencedirect.com
    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
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    sciencedirect.com/science/article/pii/S1535610819305768
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
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    ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
  61. www.mdpi.com www.mdpi.com
    Structure–Activity Relationships and Molecular Docking Analysis of Mcl-1 Targeting Renieramycin T Analogues in Patient-derived Lung Cancer Cells
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    mdpi.com/2072-6694/12/4/875
  62. link.springer.com link.springer.com
    Angiostrongylus cantonensis Galectin-1 interacts with Annexin A2 to impair the viability of macrophages via activating JNK pathway
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    link.springer.com/article/10.1186/s13071-020-04038-w
  63. Jan 2020
  64. www.sciencedirect.com www.sciencedirect.com
    The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability
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    sciencedirect.com/science/article/pii/S1535610819304787
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    Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover
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    sciencedirect.com/science/article/pii/S1097276519304976
  66. www.sciencedirect.com www.sciencedirect.com
    Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers
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    sciencedirect.com/science/article/pii/S2211124719309672
  67. Nov 2017
  68. www.sciencedirect.com www.sciencedirect.com
    Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia
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    sciencedirect.com/science/article/pii/S1535610817303641
  69. academic.oup.com academic.oup.com
    Induction of Amnion Epithelial Apoptosis by Cortisol via tPA/Plasmin System
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    academic.oup.com/endo/article/157/11/4487/2758428/Induction-of-Amnion-Epithelial-Apoptosis-by