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Combinatorial therapy regimens targeting preclinical models of melanoma resistant to immune checkpoint blockade

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1. scibot 24 Apr 2026
  
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  DOI: 10.1172/JCI185220
  
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jci.org/articles/view/185220
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Defining the antitumor mechanism of action of a clinical-stage compound as a selective degrader of the nuclear pore complex

1
1. scibot 06 Dec 2025
  
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  DOI: 10.1158/2159-8290.CD-25-0271
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12670082/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting the WSB2–NOXA axis in cancer cells for enhanced sensitivity to BCL-2 family protein inhibitors

1
1. scibot 25 Jul 2025
  
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  RRID:AB_1903909
  
  DOI: 10.7554/eLife.98372
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12286604/
Apr 2025
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Downregulation of rRNA synthesis by BCL-2 induces chemoresistance in diffuse large B cell lymphoma

1
1. scibot 24 Apr 2025
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.isci.2025.112333
  
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sciencedirect.com/science/article/pii/S2589004225005942
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis

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1. scibot 04 Apr 2025
  
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  DOI: 10.1158/1078-0432.CCR-24-2548
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11964295/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Xuebijing injection alleviates septic acute kidney injury by modulating inflammation, mitochondrial dysfunction, and endoplasmic reticulum stress

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1. scibot 02 Apr 2025
  
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  AB_1903909
  
  DOI: 10.1080/0886022X.2025.2483986
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11951319/
Feb 2025
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 07 Feb 2025
  
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  RRID:AB_1903909
  
  DOI: 10.1158/1078-0432.ccr-24-2548
  
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52.53.155.43/f141eddf8d6ed9d4f64a9be0f6055059836b8d11/PDF-html.html
Dec 2024
www.sciencedirect.com www.sciencedirect.com

GW117 induces anxiolytic effects by improving hippocampal functions

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.pbb.2024.173927
  
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sciencedirect.com/science/article/pii/S0091305724002211
Oct 2024
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Leucine restriction ameliorates Fusobacterium nucleatum-driven malignant progression and radioresistance in nasopharyngeal carcinoma

1
1. scibot 02 Oct 2024
  
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  AB_1903909
  
  DOI: 10.1016/j.xcrm.2024.101753
  
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sciencedirect.com/science/article/pii/S266637912400483X
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer

1
1. scibot 12 Sep 2024
  
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  DOI: 10.1158/2159-8290.CD-22-0649
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11372365/
May 2024
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Venetoclax acts as an immunometabolic modulator to potentiate adoptive NK cell immunotherapy against leukemia

3
1. scibot 23 May 2024
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.xcrm.2024.101580
  
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2. scibot 23 May 2024
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.xcrm.2024.101580
  
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3. scibot 23 May 2024
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.xcrm.2024.101580
  
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sciencedirect.com/science/article/pii/S2666379124002726
Mar 2024
www.nature.com www.nature.com

Light-mediated intracellular polymerization

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1. scibot 26 Mar 2024
  
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  RRID:AB_1903909
  
  DOI: 10.1038/s41596-024-00970-8
  
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nature.com/articles/s41596-024-00970-8
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins

2
1. scibot 11 Nov 2023
  
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  RRID:AB_1903909
  
  DOI: 10.1097/BS9.0000000000000168
  
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2. scibot 11 Nov 2023
  
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  RRID:AB_1903909
  
  DOI: 10.1097/BS9.0000000000000168
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10629731/
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Breast Cancer Cells are Sensitized by Piperine to Radiotherapy through Estrogen Receptor-α mediated modulation of a Key NHEJ repair protein- DNA-PK

1
1. scibot 13 Oct 2023
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.phymed.2023.155126
  
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sciencedirect.com/science/article/pii/S0944711323004865
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer

1
1. scibot 07 Jun 2023
  
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  RRID:AB_1903909
  
  DOI: 10.1158/0008-5472.CAN-22-0370
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10236151/
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer

1
1. scibot 04 May 2023
  
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  RRID:AB_1903909
  
  DOI: 10.1158/1078-0432.CCR-22-0669
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9633392/
Sep 2022
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BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer

1
1. scibot 15 Sep 2022
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.celrep.2022.111304
  
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sciencedirect.com/science/article/pii/S2211124722011287
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A

1
1. scibot 25 Jun 2022
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.isci.2022.104518
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9218363/
Apr 2022
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Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage

1
1. scibot 21 Apr 2022
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.devcel.2022.03.019
  
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sciencedirect.com/science/article/pii/S1534580722002295
Jan 2022
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AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia

1
1. scibot 05 Jan 2022
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.celrep.2021.110197
  
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sciencedirect.com/science/article/pii/S2211124721017010
Dec 2021
mct.aacrjournals.org mct.aacrjournals.org

Antibody-drug conjugate efficacy in neuroblastoma - role of payload, resistance mechanisms, target density, and antibody internalization

1
1. scibot 22 Dec 2021
  
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  RRID:AB_1903909
  
  DOI: 10.1158/1535-7163.MCT-20-1034
  
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mct.aacrjournals.org/content/20/11/2228
Nov 2021
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Interplay between protein acetylation and ubiquitination controls MCL1 protein stability

1
1. scibot 10 Nov 2021
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.celrep.2021.109988
  
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sciencedirect.com/science/article/pii/S2211124721014674
Aug 2021
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Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity

1
1. scibot 07 Aug 2021
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.cmet.2019.01.011
  
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sciencedirect.com/science/article/pii/S1550413119300117
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ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma

1
1. scibot 01 Aug 2021
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.celrep.2021.109455
  
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sciencedirect.com/science/article/pii/S221112472100872X
Jul 2021
academic.oup.com academic.oup.com

Untitled document

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1. scibot 30 Jul 2021
  
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  AB_1903909
  
  DOI: 10.1210/en.2016-1464
  
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academic.oup.com/endo/article/157/11/4487/2758428
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Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity

1
1. scibot 28 Jul 2021
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.cmet.2019.01.011
  
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  RRIDCUR:Unrecognized RRID:AB_1903909
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sciencedirect.com/science/article/pii/S1550413119300117
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Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target

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1. scibot 01 Jul 2021
  
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  4223
  
  DOI: 10.1016/j.biocel.2021.106028
  
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sciencedirect.com/science/article/pii/S1357272521001060
May 2021
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 20 May 2021
  
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  RRID:AB_1903909
  
  DOI: 10.1111/bph.15435
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15435
Nov 2020
www.authorea.com www.authorea.com

Natural Product Trienomycin A is a STAT3 pathway inhibitor that exhibits potent in vitro and in vivo efficacy against pancreatic cancer

1
1. scibot 24 Nov 2020
  
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  RRID:AB_1903909
  
  DOI: 10.22541/au.160322400.03400793/v1
  
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authorea.com/users/368637/articles/487712-natural-product-trienomycin-a-is-a-stat3-pathway-inhibitor-that-exhibits-potent-in-vitro-and-in-vivo-efficacy-against-pancreatic-cancer
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

1
1. scibot 26 Sep 2020
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.ccell.2019.12.006
  
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  RRIDCUR:Validated RRID:AB_1903909
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sciencedirect.com/science/article/pii/S1535610819305768
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531

1
1. scibot 26 Sep 2020
  
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  RRID:AB_1903909
  
  DOI: 10.7554/eLife.56913
  
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  Curator: @evieth
  
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  RRIDCUR:Validated RRID:AB_1903909
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ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
www.mdpi.com www.mdpi.com

Structure–Activity Relationships and Molecular Docking Analysis of Mcl-1 Targeting Renieramycin T Analogues in Patient-derived Lung Cancer Cells

1
1. scibot 17 Sep 2020
  
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  RRID:AB_1903909
  
  DOI: 10.3390/cancers12040875
  
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  RRID:AB_1903909 RRIDCUR:Validated
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mdpi.com/2072-6694/12/4/875
link.springer.com link.springer.com

Angiostrongylus cantonensis Galectin-1 interacts with Annexin A2 to impair the viability of macrophages via activating JNK pathway

1
1. scibot 14 Sep 2020
  
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  RRID:AB_1903909
  
  DOI: 10.1186/s13071-020-04038-w
  
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  RRID:AB_1903909 RRIDCUR:Validated
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URL

link.springer.com/article/10.1186/s13071-020-04038-w
Jan 2020
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The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability

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1. scibot 13 Jan 2020
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.ccell.2019.10.004
  
  Resource: (Cell Signaling Technology Cat# 4223, RRID:AB_1903909)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1903909
  
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  RRID:AB_1903909 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819304787
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Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1903909
  
  DOI: 10.1016/j.molcel.2019.06.040
  
  Resource: (Cell Signaling Technology Cat# 4223, RRID:AB_1903909)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1903909
  
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  RRID:AB_1903909 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519304976
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Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_1903909
  
  DOI: 10.1016/j.celrep.2019.07.063
  
  Resource: (Cell Signaling Technology Cat# 4223, RRID:AB_1903909)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1903909
  
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  RRID:AB_1903909 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719309672
Nov 2017
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Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:AB_1903909
  
  Curator: @Jmenke
  
  Resource used:
  
  (Cell Signaling Technology Cat# 4223S, RRID:AB_1903909)
  
  SciCrunch record: RRID:AB_1903909
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_1903909 RRIDCUR:Validated
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RRID:AB_1903909

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scibot

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sciencedirect.com/science/article/pii/S1535610817303641
academic.oup.com academic.oup.com

Induction of Amnion Epithelial Apoptosis by Cortisol via tPA/Plasmin System

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_1903909
  
  Curator: @bandrow
  
  Resource used:
  
  (Cell Signaling Technology Cat# 4223S, RRID:AB_1903909)
  
  SciCrunch record: RRID:AB_1903909
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_1903909
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academic.oup.com/endo/article/157/11/4487/2758428/Induction-of-Amnion-Epithelial-Apoptosis-by