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MRAP2 potentiates GPCR signaling by conserved mechanisms that are disrupted by obesity-associated genetic variants

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.117018
  
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sciencedirect.com/science/article/pii/S2211124726000963
Jan 2026
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Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.cell.2025.12.012
  
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sciencedirect.com/science/article/pii/S0092867425014254
Dec 2025
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Metformin hijacks AMPK-ERK1/2 signaling to trigger a pathogenic “selection trap” and thymic atrophy

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1. scibot 25 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116762
  
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sciencedirect.com/science/article/pii/S2211124725015347
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The accessory protein MRAP2 directly interacts with melanocortin-3 receptor to enhance signaling

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1. scibot 23 Dec 2025
  
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  RRID:AB_1904023
  
  DOI: 10.1126/scisignal.adu4315
  
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science.org/doi/10.1126/scisignal.adu4315
Oct 2025
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MRAP2 potentiates GPCR signaling by conserved mechanisms that are disrupted by obesity-associated genetic variants

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1. scibot 07 Oct 2025
  
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  DOI: 10.1101/2025.09.26.678709
  
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biorxiv.org/content/10.1101/2025.09.26.678709v1
Aug 2025
elifesciences.org elifesciences.org

Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex

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1. scibot 15 Aug 2025
  
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  DOI: 10.7554/eLife.97100
  
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elifesciences.org/articles/97100
Jun 2025
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Endosymbiont control through non-canonical immune signaling and gut metabolic remodeling

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1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115811
  
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sciencedirect.com/science/article/pii/S2211124725005820
May 2025
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1-s2.0-S2589004225009125-main-html.html

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1. scibot 18 May 2025
  
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  RRID:AB_1904023
  
  DOI: 10.1016/j.isci.2025.112651
  
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52.53.155.43/b940d5d93ef5f3ae86b7c47d70b110530336d3b3/1-s2.0-S2589004225009125-main-html.html
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Pituitary folliculo-stellate cells modulate tumor vasculature and extracellular matrix composition in experimental lactosomatotropinomas.

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.bbrc.2025.151876
  
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sciencedirect.com/science/article/pii/S0006291X2500590X
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Obesity-associated MRAP2 variants impair multiple MC4R-mediated signaling pathways

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1. scibot 18 Mar 2025
  
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  RRID:AB_1904023
  
  DOI: 10.1093/hmg/ddaf005
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11891872/
Feb 2025
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N-cadherin-triggered myosin II inactivation provides tumor cells with a mechanical cell competition advantage and chemotherapy resistance

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1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.devcel.2025.01.020
  
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sciencedirect.com/science/article/pii/S1534580725000619
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The MRAP2 accessory protein directly interacts with melanocortin-3 receptor to enhance signaling

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1. scibot 21 Dec 2024
  
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  DOI: 10.1101/2024.11.06.622243
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11580913/
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Astrocytic GAT-3 Regulates Synaptic Transmission and Memory Formation in the Dentate Gyrus

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1. scibot 06 Dec 2024
  
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  DOI: 10.1002/glia.24649
  
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onlinelibrary.wiley.com/doi/10.1002/glia.24649
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance

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1. scibot 10 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111139
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11539641/
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Simple aneuploidy evades p53 surveillance and promotes niche factor-independent growth in human intestinal organoids

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1. scibot 08 Oct 2024
  
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  DOI: 10.1091/mbc.E24-04-0166
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11321050/
Sep 2024
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GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.ccell.2024.08.006
  
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sciencedirect.com/science/article/pii/S1535610824003052
Apr 2024
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Generation of a homozygous DNAJC19 knockout human embryonic stem cell line by CRISPR/ Cas9 system

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1. scibot 30 Apr 2024
  
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  RRID:AB_1904023
  
  DOI: 10.1016/j.scr.2024.103427
  
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sciencedirect.com/science/article/pii/S1873506124001259
Mar 2024
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The zebrafish heart harbors a thermogenic beige fat depot analog of human epicardial adipose tissue

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1. scibot 21 Mar 2024
  
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  RRID:AB_1904023
  
  DOI: 10.1016/j.celrep.2024.113955
  
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sciencedirect.com/science/article/pii/S2211124724002833
Feb 2024
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The Calmodulin-interacting peptide Pcp4a regulates feeding state-dependent behavioral choice in zebrafish

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1. scibot 02 Feb 2024
  
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  DOI: 10.1016/j.neuron.2024.01.001
  
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sciencedirect.com/science/article/pii/S0896627324000011
Jan 2024
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Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer

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1. scibot 23 Jan 2024
  
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  DOI: 10.1016/j.celrep.2024.113684
  
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sciencedirect.com/science/article/pii/S2211124724000123
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Cytoneme signaling provides essential contributions to mammalian tissue patterning

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1. scibot 07 Jan 2024
  
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  DOI: 10.1016/j.cell.2023.12.003
  
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sciencedirect.com/science/article/pii/S0092867423013338
Oct 2023
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Alpha-1 adrenergic signaling drives cardiac regeneration via extracellular matrix remodeling transcriptional program in zebrafish macrophages

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1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.devcel.2023.09.011
  
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sciencedirect.com/science/article/pii/S1534580723005130
Jun 2023
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QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism

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1. scibot 28 Jun 2023
  
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  RRID: AB_1904023
  
  DOI: 10.1016/j.cell.2023.05.047
  
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sciencedirect.com/science/article/pii/S0092867423005986
Apr 2023
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Identification and characterization of the CDK1-BMAL1-UHRF1 pathway driving tumor progression

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1. scibot 13 Apr 2023
  
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  RRID:AB_1904023
  
  DOI: 10.1016/j.isci.2023.106544
  
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sciencedirect.com/science/article/pii/S2589004223006211
Jan 2023
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Seasonal cues act through the circadian clock and pigment-dispersing factor to control EYES ABSENT and downstream physiological changes

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1. scibot 28 Jan 2023
  
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  RRID:AB_1904023
  
  DOI: 10.1016/j.cub.2023.01.006
  
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sciencedirect.com/science/article/pii/S0960982223000064
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis

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1. scibot 15 Jan 2023
  
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  RRID:AB_1904023
  
  DOI: 10.26508/lsa.202201457
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9834662/
academic.oup.com academic.oup.com

Genotypic and phenotypic spectrum and pathogenesis of WNT1 variants in a large cohort of patients with OI/osteoporosis

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1. scibot 14 Jan 2023
  
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  RRID:AB_1904023
  
  DOI: 10.1210/clinem/dgac752
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac752/6967739
Oct 2022
journals.lww.com journals.lww.com

Use of a tissue clearing technique combined with retrograde ... : Neural Regeneration Research

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1. scibot 08 Oct 2022
  
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  RRID:AB_1904023
  
  DOI: 10.4103/1673-5374.353852
  
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journals.lww.com/nrronline/Fulltext/2023/04000/Use_of_a_tissue_clearing_technique_combined_with.40.aspx
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Using pERK immunostaining to quantify neuronal activity induced by stress in zebrafish larvae

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1. scibot 04 Oct 2022
  
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  DOI: 10.1016/j.xpro.2022.101731
  
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sciencedirect.com/science/article/pii/S2666166722006116
Sep 2022
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Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses

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1. scibot 30 Sep 2022
  
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  DOI: 10.1016/j.ccell.2022.09.007
  
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sciencedirect.com/science/article/pii/S1535610822004366
Apr 2022
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Efficient generation of locus-specific human CAR-T cells with CRISPR/cCas12a

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1. scibot 15 Apr 2022
  
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  Cell Signaling TechnologyCat# 4410
  
  DOI: 10.1016/j.xpro.2022.101321
  
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sciencedirect.com/science/article/pii/S2666166722002015
Mar 2022
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Hypothalamic Galanin-producing neurons regulate stress in zebrafish through a peptidergic, self-inhibitory loop

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  DOI: 10.1016/j.cub.2022.02.011
  
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sciencedirect.com/science/article/pii/S0960982222002330
Jan 2022
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IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment

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1. scibot 27 Jan 2022
  
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  DOI: 10.1016/j.immuni.2021.12.016
  
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sciencedirect.com/science/article/pii/S1074761321005525
Oct 2021
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Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates

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1. scibot 14 Oct 2021
  
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  DOI: 10.1016/j.molcel.2021.09.021
  
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sciencedirect.com/science/article/pii/S1097276521007735
Jul 2021
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Syntaxin 6‐mediated exosome secretion regulates enzalutamide resistance in prostate cancer

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1. scibot 31 Jul 2021
  
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  Anti‐mouse IgG Alexa Fluor 647
  
  DOI: 10.1002/mc.23129
  
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onlinelibrary.wiley.com/doi/10.1002/mc.23129
Dec 2020
www.cell.com www.cell.com

Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε

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1. scibot 10 Dec 2020
  
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  RRID:AB_1904023
  
  DOI: 10.1016/j.molcel.2020.10.016
  
  Resource: (Cell Signaling Technology Cat# 4410, RRID:AB_1904023)
  
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cell.com/molecular-cell/fulltext/S1097-2765(20)30723-1
Nov 2020
www.sciencedirect.com www.sciencedirect.com

Early-Life Stress Regulates Cardiac Development through an IL-4-Glucocorticoid Signaling Balance

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1. scibot 25 Nov 2020
  
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  RRID:AB_1904023
  
  DOI: 10.1016/j.celrep.2020.108404
  
  Resource: (Cell Signaling Technology Cat# 4410, RRID:AB_1904023)
  
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sciencedirect.com/science/article/pii/S2211124720313930
Sep 2020
www.jneurosci.org www.jneurosci.org

Deletion of the mitochondrial matrix protein cyclophilin-D prevents parvalbumin interneuron dysfunction and cognitive deficits in a mouse model of NMDA hypofunction

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1. scibot 08 Sep 2020
  
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  RRID:AB_1904023
  
  DOI: 10.1523/JNEUROSCI.0880-20.2020
  
  Resource: (Cell Signaling Technology Cat# 4410, RRID:AB_1904023)
  
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jneurosci.org/content/40/32/6121
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint

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1. scibot 13 Jan 2020
  
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  RRID:AB_10694714
  
  DOI: 10.7554/eLife.44353
  
  Resource: (Cell Signaling Technology Cat# 4410, RRID:AB_1904023)
  
  Curator: @evieth
  
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  RRID:AB_1904023 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6561707/
Nov 2018
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Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors

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1. scibot 05 Nov 2018
  
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  RRID:AB_1904023
  
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sciencedirect.com/science/article/pii/S1535610818302265