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May 2026
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An optimized method to visualize lipid droplets in mouse brain tissue

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sciencedirect.com/science/article/pii/S2667237526001554
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Palmitoylation of death receptor p75NTR contributes to Alzheimer’s disease progression by regulating APP trafficking and degradation

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pmc.ncbi.nlm.nih.gov/articles/PMC13151129/
Apr 2026
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A stress-induced PI3P complex controls autophagy in erythroid precursors

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  DOI: 10.1016/j.isci.2026.115182
  
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Mar 2026
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A Nanoparticle-Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

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1. scibot 31 Mar 2026
  
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  DOI: 10.1002/advs.202516075
  
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Feb 2026
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Liquid-liquid phase separation of EphB4 drives pulmonary hypertension via YAP activation

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  DOI: 10.1016/j.celrep.2026.116992
  
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Dec 2025
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PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in a drug-tolerant hepatocyte environment

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  DOI: 10.7554/eLife.103817
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12685304/
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BPS Publications

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1. scibot 06 Dec 2025
  
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  DOI: 10.1111/bph.70258
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70258
Sep 2025
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PKD3 localizes to late endosomes to maintain Rab7-dependent endolysosomal homeostasis

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  DOI: 10.1016/j.isci.2025.113408
  
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sciencedirect.com/science/article/pii/S2589004225016694
Aug 2025
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dhar-et-al-programmed-cell-revival-from-imminent-cell-death-enhances-tissue-repair-and-regeneration-html.html

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52.53.155.43/6e1a51ae3d978e6c74ed455dd826dbf65caf9c68/dhar-et-al-programmed-cell-revival-from-imminent-cell-death-enhances-tissue-repair-and-regeneration-html.html
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TCF25 serves as a nutrient sensor to orchestrate metabolic adaptation and cell death by enhancing lysosomal acidification under glucose starvation

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  DOI: 10.1016/j.celrep.2025.116186
  
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A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression

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  DOI: 10.1158/0008-5472.CAN-24-4774
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12317733/
Jul 2025
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2025.07.14.664742v1.full-html.html

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1. scibot 25 Jul 2025
  
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TNF-α-NF-κB activation through pathological α-Synuclein disrupts the BBB and exacerbates axonopathy

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  DOI: 10.1016/j.celrep.2025.116001
  
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The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

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1. scibot 08 Jul 2025
  
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  DOI: 10.7554/eLife.101984
  
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elifesciences.org/articles/101984
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Interconnections of insulin/IGF-1 signaling and autophagy abnormalities in Alzheimer's disease

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  DOI: 10.1002/alz.70099
  
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alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.70099
Jun 2025
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Immune targeting of triple-negative breast cancer through a clinically actionable STING agonist-CAR T cell platform

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  DOI: 10.1016/j.xcrm.2025.102198
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12281382/
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A triple serine motif in the intracellular domain of SorCS2 impacts its cellular signaling

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  DOI: 10.1016/j.isci.2025.112695
  
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sciencedirect.com/science/article/pii/S2589004225009563
May 2025
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Glycerophospholipid metabolism licenses IgE-mediated mast cell degranulation

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1. scibot 22 May 2025
  
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RNF13 variants L311S and L312P associated with developmental epileptic encephalopathy alter dendritic organization in hippocampal neurons

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pmc.ncbi.nlm.nih.gov/articles/PMC12018061/
Apr 2025
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The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage

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pmc.ncbi.nlm.nih.gov/articles/PMC12081312/
Mar 2025
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Neuropilin 2 stabilises adherens junctions and protects against endothelial activation by promoting the interaction between VE cadherin and p120 catenin

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  DOI: 10.1101/2025.03.09.642194
  
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biorxiv.org/content/10.1101/2025.03.09.642194v1
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IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex

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Feb 2025
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BACE1-dependent cleavage of GABAA receptor contributes to neural hyperexcitability and disease progression in Alzheimer’s disease

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  DOI: 10.1016/j.neuron.2025.01.030
  
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Loss of the proton-activated chloride channel in neurons impairs AMPA receptor endocytosis and LTD via endosomal hyper-acidification

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Novel Pannexin 1 isoform is increased in cancer

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  DOI: 10.1101/2024.09.09.612143
  
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52.53.155.43/248e2b0e257da849dadde63c071f77bcede2b26b/2024.09.09.612143v3.full-html.html
Jan 2025
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G6PD deficiency triggers dopamine loss and the initiation of Parkinson’s disease pathogenesis

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  DOI: 10.1016/j.celrep.2024.115178
  
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Dec 2024
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The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation

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Low-affinity ligands of the epidermal growth factor receptor are long-range signal transmitters in collective cell migration of epithelial cells

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Nov 2024
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VPS4A is the selective receptor for lipophagy in mice and humans

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Oct 2024
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Arf1-dependent LRBA recruitment to Rab4 endosomes is required for endolysosome homeostasis

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  DOI: 10.1083/jcb.202401167
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11449124/
Sep 2024
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Systems mapping of bidirectional endosomal transport through the crowded cell

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sciencedirect.com/science/article/pii/S0960982224011382
Aug 2024
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Untitled document

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  DOI: 10.1091/mbc.E18-01-0007
  
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molbiolcell.org/doi/full/10.1091/mbc.E18-01-0007
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Therapeutic application of extracellular vesicular EGFR isoform D as a co-drug to target squamous cell cancers with tyrosine kinase inhibitors

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sciencedirect.com/science/article/pii/S1534580724004428
Jun 2024
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Cardioprotective effect of Cinnamamide derivative compound 10 against myocardial ischemia-reperfusion through regulating cardiac autophagy via Sirt1

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sciencedirect.com/science/article/pii/S0753332224007030
May 2024
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Myosin phosphatase targeting subunit1 controls localization and motility of Rab7-containing vesicles: Is myosin phosphatase a cytoplasmic dynein regulator?

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  DOI: 10.1002/cm.21871
  
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Initiation of acute pancreatitis in mice is independent of fusion between lysosomes and zymogen granules

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Glia trigger endocytic clearance of axonal proteins to promote rodent myelination

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Cytoneme signaling provides essential contributions to mammalian tissue patterning

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Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling

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Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy

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S-acylation of the Wnt receptor Frizzled-5 by zDHHC5 controls its cellular localization and synaptogenic activity in the rodent hippocampus

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Homotypic SCOTIN assemblies form ER-endosome membrane contacts and regulate endosome dynamics

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The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules

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Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity

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Celastrol directly binds with VAMP7 and RAB7 to inhibit autophagy and induce apoptosis in preadipocytes

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Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway

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H2-induced transient upregulation of phospholipids with suppression of energy metabolism

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Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation

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Protocol to purify and detect ubiquitinated phospholipids in budding yeast and human cell lines

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USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction

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Dysregulated endolysosomal trafficking in cells arrested in the G1 phase of the host cell cycle impairs Salmonella vacuolar replication

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Ubiquitination of phosphatidylethanolamine in organellar membranes

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Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167

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Impaired interferon-γ signaling promotes the development of silicosis

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C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus

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ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling

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Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis

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Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia

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Septin 9 and phosphoinositides regulate lysosome localization and their association with lipid droplets

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Activity-dependent PI4P synthesis by PI4KIIIα regulates long-term synaptic potentiation

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LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function

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Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance

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Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis

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RNF13 Dileucine Motif Variants L311S and L312P Interfere with Endosomal Localization and AP-3 Complex Association

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Interactome analysis reveals endocytosis and membrane recycling of EpCAM during differentiation of embryonic stem cells and carcinoma cells

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Pro-inflammatory β cell small extracellular vesicles induce β cell failure through activation of the CXCL10/CXCR3 axis in diabetes

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Interaction and Subcellular Association of PRRT1/SynDIG4 With AMPA Receptors

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Compromised mitochondrial quality control triggers lipin1-related rhabdomyolysis

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Coupling of microtubule motors with AP-3 generated organelles in axons by NEEP21 family member calcyon

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Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes

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A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary CaVβ subunits

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EBI2 Is Temporarily Upregulated in MO3.13 Oligodendrocytes during Maturation and Regulates Remyelination in the Organotypic Cerebellar Slice Model

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Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q

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TBC1D5-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry

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Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy

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Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury

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Sensory Axon Growth Requires Spatiotemporal Integration of CaSR and TrkB Signaling

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A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells

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Lipocalin-2 Regulates Epidermal Growth Factor Receptor Intracellular Trafficking

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Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut

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  RRID:AB_1904103
  
  DOI: 10.1016/j.celrep.2018.11.073
  
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  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S2211124718318497
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A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion

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1. scibot 12 Jan 2020
  
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  AB_1904103
  
  DOI: 10.7554/eLife.41801
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6435326/
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Untitled document

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1. scibot 12 Jan 2020
  
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  RRID:AB_1904103
  
  DOI: 10.1016/j.devcel.2019.03.011
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1534580719301881
Nov 2018
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Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response

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1. scibot 05 Nov 2018
  
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The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis

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1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages

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1. scibot 05 Nov 2018
  
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  9367
  
  Curator: @Jmenke
  
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Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM

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1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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A Novel Class of ER Membrane Proteins Regulates ER-Associated Endosome Fission

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1. scibot 05 Nov 2018
  
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A Sialylated Voltage-Dependent Ca2+ Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells

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1. scibot 05 Nov 2018
  
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  RRID:AB_1904103
  
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Nov 2017
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The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes

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1. scibot 08 Nov 2017
  
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  RRID:AB_1904103
  
  Curator: @kaitlinsung
  
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nature.com/articles/s41598-017-07667-x
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Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks

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1. scibot 08 Nov 2017
  
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  Curator: @kaitlinsung
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5376188/

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