Hypothesis

33 Matching Annotations

Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Functional mapping of epigenomic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes

1
1. scibot 23 Nov 2025
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1158/2159-8290.CD-24-1565
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12469823/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

EML4-ALK variant-specific genetic interactions shape lung tumorigenesis

1
1. scibot 23 Nov 2025
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1158/2159-8290.CD-24-1417
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12479099/
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Epigenome profiling identifies H3K27me3 regulation of extracellular matrix composition in human corticogenesis

1
1. scibot 23 Jul 2025
  
  in Public
  
  RRID:AB_1950414
  
  DOI: 10.1016/j.neuron.2025.06.016
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S089662732500474X
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation

1
1. scibot 23 Jan 2025
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.cell.2024.12.009
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12160003/
www.sciencedirect.com www.sciencedirect.com

Single-molecule systems for the detection and monitoring of plasma-circulating nucleosomes and oncoproteins in diffuse midline glioma

1
1. scibot 14 Jan 2025
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.xcrm.2024.101918
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S266637912400689X
Nov 2024
www.sciencedirect.com www.sciencedirect.com

ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

1
1. scibot 24 Nov 2024
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.cmet.2024.10.015
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S155041312400411X
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Promoter DNA methylation and transcription factor condensation are linked to transcriptional memory in mammalian cells

1
1. scibot 10 Sep 2024
  
  in Public
  
  AB_1950412
  
  DOI: 10.1016/j.cels.2024.08.007
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2405471224002370
Aug 2024
www.biorxiv.org www.biorxiv.org

Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes

1
1. scibot 25 Aug 2024
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1101/2024.08.19.607671
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

biorxiv.org/content/10.1101/2024.08.19.607671v1
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer

1
1. scibot 05 Apr 2024
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.ccell.2024.03.005
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610824000904
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape

1
1. scibot 29 Mar 2024
  
  in Public
  
  AB_1950412
  
  DOI: 10.1016/j.molcel.2024.02.032
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276524001758
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer

1
1. scibot 02 Feb 2024
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.xcrm.2024.101396
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379124000053
Oct 2023
www.sciencedirect.com www.sciencedirect.com

mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis

1
1. scibot 10 Oct 2023
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.molcel.2021.03.009
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276521001775
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ethanol changes Nestin-promoter induced neural stem cells to disturb newborn dendritic spine remodeling in the hippocampus of mice

1
1. scibot 20 Sep 2023
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.4103/1673-5374.379051
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10503613/
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity

1
1. scibot 02 Jun 2023
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.ccell.2023.05.005
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610823001733
Apr 2023
journals.lww.com journals.lww.com

Synergistic antiproliferative activity of quercetin and... : Anti-Cancer Drugs

1
1. scibot 28 Apr 2023
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1097/CAD.0000000000001514
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

journals.lww.com/anti-cancerdrugs/fulltext/2023/11000/tach101,_a_first_in_class_pan_inhibitor_of_kdm4.8.aspx
Jan 2023
www.sciencedirect.com www.sciencedirect.com

RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer

1
1. scibot 21 Jan 2023
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.celrep.2023.112016
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472300027X
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas

1
1. scibot 18 Jun 2022
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.molcel.2022.05.023
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276522004907
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Linkage of methionine addiction, histone lysine hypermethylation, and malignancy

1
1. scibot 08 Apr 2022
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.isci.2022.104162
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004222004321
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity

1
1. scibot 23 Feb 2022
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.celrep.2022.110422
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722001462
Oct 2021
www.sciencedirect.com www.sciencedirect.com

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity

1
1. scibot 21 Oct 2021
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.chembiol.2021.10.008
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945621004426
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Low folate induces abnormal neuronal maturation and DNA hypomethylation of neuronal differentiation-related genes in cultured mouse neural stem and progenitor cells

1
1. scibot 25 Sep 2021
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.heliyon.2021.e08071
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2405844021021745
May 2021
www.sciencedirect.com www.sciencedirect.com

Decoding dynamic epigenetic landscapes in human oocytes using single-cell multi-omics sequencing

1
1. scibot 06 May 2021
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.stem.2021.04.012
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590921001697
Apr 2021
www.sciencedirect.com www.sciencedirect.com

The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells

1
1. scibot 20 Apr 2021
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.devcel.2021.03.008
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580721002057
www.sciencedirect.com www.sciencedirect.com

mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis

1
1. scibot 02 Apr 2021
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.molcel.2021.03.009
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276521001775
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SETD2 mutation in renal clear cell carcinoma suppress autophagy via regulation of ATG12

1
1. scibot 24 Feb 2021
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1038/s41419-020-2266-x
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6985262/
www.sciencedirect.com www.sciencedirect.com

Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1

1
1. scibot 24 Feb 2021
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.celrep.2021.108749
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_1950412

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721000620
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells

1
1. scibot 12 Sep 2020
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.molcel.2020.03.010
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_1950412

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276520301581
Jan 2020
www.sciencedirect.com www.sciencedirect.com

One-Carbon Metabolism Supports S-Adenosylmethionine and Histone Methylation to Drive Inflammatory Macrophages

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.molcel.2019.06.039
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_1950412

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276519304964
www.sciencedirect.com www.sciencedirect.com

CoBATCH for High-Throughput Single-Cell Epigenomic Profiling

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.molcel.2019.07.015
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_1950412

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276519305453
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.ccell.2019.03.006
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_1950412

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6812656/
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.1016/j.ccell.2019.03.006
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_1950412

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819301515
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:AB_1950412
  
  DOI: 10.7554/eLife.40364
  
  Resource: (Cell Signaling Technology Cat# 4909, RRID:AB_1950412)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_1950412
  
  What is this?
  
  RRID:AB_1950412 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_1950412

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6344081/
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_1950412
  
  Resource used:
  
  (Cell Signaling Technology Cat# 4909P, RRID:AB_1950412)
  
  SciCrunch record: RRID:AB_1950412
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_1950412
Visit annotations in context

Tags

RRID:AB_1950412

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413118305072