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49 Matching Annotations

Nov 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

L-Phenylalanine is a metabolic checkpoint of human Th2 cells

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.xcrm.2025.102466
  
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sciencedirect.com:5037/science/article/pii/S2666379125005397
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Deep profiling of human T cells defines compartmentalized clones and phenotypic trajectories across blood and tonsils

1
1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.immuni.2025.10.025
  
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sciencedirect.com:5037/science/article/pii/S1074761325004790
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Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells

1
1. scibot 13 Nov 2025
  
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  DOI: 10.1016/j.xcrm.2025.102446
  
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sciencedirect.com/science/article/pii/S2666379125005191
Oct 2025
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ROR2-specific CAR T cells are effective against hematologic and solid tumors and well tolerated in mice

1
1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102400
  
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sciencedirect.com/science/article/pii/S2666379125004732
Aug 2025
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Multimodal targeting of metastatic renal cell carcinoma via CD70-directed allogeneic CAR-NKT cells

1
1. scibot 30 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102321
  
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sciencedirect.com/science/article/pii/S2666379125003945
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Overcoming ovarian cancer resistance and evasion to CAR-T cell therapy by harnessing allogeneic CAR-NKT cells

1
1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.medj.2025.100804
  
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sciencedirect.com/science/article/pii/S2666634025002314
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

C-reactive protein induced T cell activation is an indirect monocyte-dependent mechanism involving the CD80/CD28 pathway

1
1. scibot 05 Aug 2025
  
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  DOI: 10.3389/fimmu.2025.1622865
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12313514/
Jul 2025
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Cancer immunology data engine reveals secreted AOAH as a potential immunotherapy

1
1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.07.004
  
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sciencedirect.com/science/article/pii/S0092867425007937
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Protocol for assessing pharmacokinetics and pharmacodynamics of human CAR-NKT cells in humanized mouse models using bioluminescence imaging

1
1. scibot 22 Jul 2025
  
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  DOI: 10.1016/j.xpro.2025.103957
  
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sciencedirect.com/science/article/pii/S2666166725003636
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Membrane-bound IL-15 co-expression powers a potent and persistent CD70-targeted TRuC T-cell therapy

1
1. scibot 18 Jun 2025
  
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  AB_2044006
  
  DOI: 10.3389/fimmu.2025.1609658
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12162932/
52.53.155.43 52.53.155.43

1-s2.0-S258900422501065X-main-html.html

1
1. scibot 03 Jun 2025
  
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  AB_2044006
  
  DOI: 10.1016/j.isci.2025.112804
  
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52.53.155.43/4138fd434baf85a642a8446d7ef9653aa8b8580b/1-s2.0-S258900422501065X-main-html.html
May 2025
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Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis

1
1. scibot 22 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.032
  
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sciencedirect.com/science/article/pii/S0092867425005021
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Protocol to generate allorejection-resistant universal CAR-NKT cells and evaluate their efficacy, mechanism of action, safety, and immunogenicity

1
1. scibot 19 May 2025
  
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  RRID:AB_2044006
  
  DOI: 10.1016/j.xpro.2025.103810
  
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sciencedirect.com/science/article/pii/S2666166725002163
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Protocol to profile tumor and microenvironment from ovarian cancer patient samples and evaluate cell-based therapy using in vitro killing assays

1
1. scibot 18 Apr 2025
  
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  DOI: 10.1016/j.xpro.2025.103742
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12002649/
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Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity

1
1. scibot 15 Apr 2025
  
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  RRID:AB_2044006
  
  DOI: 10.1016/j.cell.2025.03.017
  
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sciencedirect.com/science/article/pii/S0092867425002909
Mar 2025
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Targeting tumor monocyte-intrinsic PD-L1 by rewiring STING signaling and enhancing STING agonist therapy

1
1. scibot 11 Mar 2025
  
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  RRID:AB_2044006
  
  DOI: 10.1016/j.ccell.2025.02.014
  
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sciencedirect.com/science/article/pii/S1535610825000662
Feb 2025
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An epitope-directed mRNA vaccine inhibits tumor metastasis through the blockade of MICA/B α1/2 shedding

1
1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2025.101981
  
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sciencedirect.com/science/article/pii/S2666379125000540
www.cell.com www.cell.com

Genomic mediators of acquired resistance to immunotherapy in metastatic melanoma

1
1. scibot 14 Feb 2025
  
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  RRID:AB_2044006
  
  DOI: 10.1016/j.ccell.2025.01.009
  
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cell.com/cancer-cell/abstract/S1535-6108(25)00027-3
Jan 2025
www.nature.com www.nature.com

Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture

1
1. scibot 31 Jan 2025
  
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  DOI: 10.1038/s41596-024-01077-w
  
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nature.com/articles/s41596-024-01077-w
Dec 2024
www.cell.com www.cell.com

Targeting P4HA1 promotes CD8+ T cell progenitor expansion toward immune memory and systemic anti-tumor immunity

1
1. scibot 29 Dec 2024
  
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  RRID:AB_2044006
  
  DOI: 10.1016/j.ccell.2024.12.001
  
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cell.com/cancer-cell/abstract/S1535-6108(24)00476-8
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dysfunctional bronchoalveolar effector memory CD8+ T cells in tuberculosis-exposed people living with antiretroviral-naïve HIV infection

1
1. scibot 21 Nov 2024
  
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  RRID:AB_2044006
  
  DOI: 10.1016/j.isci.2024.111137
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11575450/
Sep 2024
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Sirolimus reduces T cell cycling, immune checkpoint marker expression, and HIV-1 DNA in people with HIV

1
1. scibot 26 Sep 2024
  
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  RRID:AB_2044006
  
  DOI: 10.1016/j.xcrm.2024.101745
  
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sciencedirect.com/science/article/pii/S2666379124004750
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Bystander Activation of Pulmonary Trm Cells Attenuates the Severity of Bacterial Pneumonia by Enhancing Neutrophil Recruitment

1
1. scibot 25 Sep 2024
  
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  RRID:AB_2044006
  
  DOI: 10.1016/j.celrep.2019.11.103
  
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sciencedirect.com/science/article/pii/S2211124719316031
Jun 2024
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Protocol for in vitro co-culture assay for rapid expansion of human T cell acute lymphoblastic leukemia

1
1. scibot 07 Jun 2024
  
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  DOI: 10.1016/j.xpro.2024.103103
  
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sciencedirect.com/science/article/pii/S2666166724002685
Nov 2023
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Prostate cancer cell-derived exosomal IL-8 fosters immune evasion by disturbing glucolipid metabolism of CD8+ T cell

1
1. scibot 28 Nov 2023
  
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  RRID:AB_2044006
  
  DOI: 10.1016/j.celrep.2023.113424
  
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sciencedirect.com/science/article/pii/S2211124723014365
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Vpr attenuates antiviral immune responses and is critical for full pathogenicity of SIVmac239 in rhesus macaques

1
1. scibot 18 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108351
  
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sciencedirect.com/science/article/pii/S2589004223024288
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Profiling ovarian cancer tumor and microenvironment during disease progression for cell-based immunotherapy design

2
1. scibot 11 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.107952
  
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2. scibot 01 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.107952
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10558812/
Apr 2023
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Multiomic Landscape of Immune Pathogenesis in Kimura’s Disease

1
1. scibot 26 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106559
  
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sciencedirect.com/science/article/pii/S2589004223006363
aacrjournals.org aacrjournals.org

Targeting MDSC differentiation using ATRA: a phase I/II clinical trial combining pembrolizumab and all-trans retinoic acid for metastatic melanoma

1
1. scibot 21 Apr 2023
  
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  DOI: 10.1158/1078-0432.CCR-22-2495
  
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aacrjournals.org/clincancerres/article/29/7/1209/718765/Targeting-MDSC-Differentiation-Using-ATRA-A-Phase
onlinelibrary.wiley.com onlinelibrary.wiley.com

ERK Inhibition Promotes Engraftment of Allografts by Reprogramming T-Cell Metabolism

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1. scibot 06 Apr 2023
  
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  DOI: 10.1002/advs.202206768
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202206768
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Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance

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1. scibot 06 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112314
  
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sciencedirect.com/science/article/pii/S221112472300325X
Oct 2022
www.science.org www.science.org

PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease

1
1. scibot 25 Oct 2022
  
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  DOI: 10.1126/sciadv.abn6545
  
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science.org/doi/10.1126/sciadv.abn6545
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PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease

1
1. scibot 07 Oct 2022
  
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  DOI: 10.1126/sciadv.abn6545
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9491709/
Aug 2022
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Off-The-Shelf Third-Party HSC-Engineered iNKT Cells for Ameliorating GvHD While Preserving GvL Effect in the Treatment of Blood Cancers

1
1. scibot 17 Aug 2022
  
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  RRID:AB_2044006
  
  DOI: 10.1016/j.isci.2022.104859
  
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sciencedirect.com/science/article/pii/S2589004222011312
Mar 2022
www.cell.com www.cell.com

Facile discovery of surrogate cytokine agonists

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1. scibot 31 Mar 2022
  
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  DOI: 10.1016/j.cell.2022.02.025
  
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cell.com/cell/fulltext/S0092-8674(22)00247-1
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Single-cell Temporal Analysis of Natural Dengue Infection Reveals Skin-Homing Lymphocyte Expansion One Day before Defervescence

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1. scibot 26 Mar 2022
  
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  DOI: 10.1016/j.isci.2022.104034
  
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sciencedirect.com/science/article/pii/S2589004222003042
Dec 2021
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CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia

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1. scibot 01 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110079
  
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sciencedirect.com/science/article/pii/S2211124721015709
Nov 2021
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Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy

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1. scibot 17 Nov 2021
  
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  DOI: 10.1016/j.xcrm.2021.100449
  
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sciencedirect.com/science/article/pii/S2666379121003177
Sep 2021
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Methods for Studying Mouse and Human Invariant Natural Killer T Cells

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1. scibot 21 Sep 2021
  
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  DOI: 10.1007/978-1-0716-1775-5_4
  
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link.springer.com/protocol/10.1007/978-1-0716-1775-5_4
Aug 2021
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Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

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1. scibot 15 Aug 2021
  
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  DOI: 10.1016/j.cell.2021.07.023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8299217/
Jul 2021
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Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma

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1. scibot 16 Jul 2021
  
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  DOI: 10.1016/j.immuni.2021.06.013
  
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sciencedirect.com/science/article/pii/S1074761321002570
Jun 2021
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Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2

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1. scibot 26 Jun 2021
  
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  DOI: 10.1016/j.xcrm.2021.100327
  
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sciencedirect.com/science/article/pii/S2666379121001701
May 2021
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Measuring the effect of drug treatments on primary human CD8+ T cell activation and cytolytic potential

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1. scibot 21 May 2021
  
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  DOI: 10.1016/j.xpro.2021.100549
  
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sciencedirect.com/science/article/pii/S2666166721002562
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Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineage Specification Trajectories and a Commitment Spectrum in T Cell Development

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1. scibot 06 May 2021
  
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  DOI: 10.1016/j.immuni.2020.05.010
  
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sciencedirect.com/science/article/pii/S1074761320302181
Apr 2021
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Passive Transfer of Vaccine-Elicited Antibodies Protects against SIV in Rhesus Macaques

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1. scibot 24 Apr 2021
  
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  APC/Cyanine7 anti-human CD8 Antibody
  
  DOI: 10.1016/j.cell.2020.08.033
  
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sciencedirect.com/science/article/pii/S0092867420310758
Sep 2020
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Development of CAR-T cell therapy for B-ALL using a point-of-care approach

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1. scibot 23 Sep 2020
  
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  DOI: 10.1080/2162402X.2020.1752592
  
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Jan 2020
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Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.stem.2019.08.004
  
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Nov 2018
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Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo

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sciencedirect.com/science/article/pii/S1931312817305450