34 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Transient splicing inhibition causes persistent DNA damage and chemotherapy vulnerability in triple-negative breast cancer
    1
    1. scibot 17 Sep 2024
      AB_2067762

      DOI: 10.1016/j.celrep.2024.114751

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    sciencedirect.com/science/article/pii/S2211124724011021
  3. Aug 2024
  4. www.sciencedirect.com www.sciencedirect.com
    RAD51 protects abasic sites to prevent replication fork breakage
    1
    1. scibot 23 Aug 2024
      AB_2067762

      DOI: 10.1016/j.molcel.2024.07.004

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

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    sciencedirect.com/science/article/pii/S109727652400580X
  5. Feb 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
    1
    1. scibot 23 Feb 2024
      RRID:AB_2067762

      DOI: 10.1016/j.celrep.2024.113845

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

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    sciencedirect.com/science/article/pii/S2211124724001736
  7. Jan 2024
  8. www.sciencedirect.com www.sciencedirect.com
    BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution
    1
    1. scibot 25 Jan 2024
      RRID: AB_2067762

      DOI: 10.1016/j.molcel.2023.12.040

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      Curator: @abever99

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    sciencedirect.com/science/article/pii/S1097276523010869
  9. www.sciencedirect.com www.sciencedirect.com
    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
    1
    1. scibot 25 Jan 2024
      RRID:AB_2067762

      DOI: 10.1016/j.molcel.2023.12.039

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    sciencedirect.com/science/article/pii/S1097276523010857
  10. Oct 2023
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms
    1
    1. scibot 06 Oct 2023
      AB_2067762

      DOI: 10.1016/j.celrep.2023.112792

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    ncbi.nlm.nih.gov/pmc/articles/PMC10529362/
  12. Jul 2023
  13. www.sciencedirect.com www.sciencedirect.com
    Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein
    1
    1. scibot 27 Jul 2023
      RRID:AB_2067762

      DOI: 10.1016/j.molcel.2023.06.031

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    sciencedirect.com/science/article/pii/S1097276523005075
  14. Jun 2023
  15. www.sciencedirect.com www.sciencedirect.com
    FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
    1
    1. scibot 23 Jun 2023
      RRID:AB_2067762

      DOI: 10.1016/j.celrep.2023.112668

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    sciencedirect.com/science/article/pii/S2211124723006794
  16. Dec 2022
  17. www.sciencedirect.com www.sciencedirect.com
    POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells
    1
    1. scibot 01 Dec 2022
      RRID:AB_206776

      DOI: 10.1016/j.molcel.2022.11.008

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

      Curator: @a5munoz

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      RRIDCUR:Unresolved RRID:AB_2067762
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    sciencedirect.com/science/article/pii/S109727652201070X
  18. Sep 2022
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CANCER-ASSOCIATED SF3B1 MUTATIONS CONFER A BRCA-LIKE CELLULAR PHENOTYPE AND SYNTHETIC LETHALITY TO PARP INHIBITORS
    1
    1. scibot 02 Sep 2022
      RRID:AB_2067762

      DOI: 10.1158/0008-5472.CAN-21-1843

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    ncbi.nlm.nih.gov/pmc/articles/PMC7612475/
  20. Aug 2022
  21. www.sciencedirect.com www.sciencedirect.com
    Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells
    1
    1. scibot 26 Aug 2022
      RRID:AB_2067762

      DOI: 10.1016/j.molcel.2022.07.011

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    sciencedirect.com/science/article/pii/S1097276522007079
  22. Feb 2022
  23. www.sciencedirect.com www.sciencedirect.com
    Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy
    2
    1. scibot 11 Feb 2022
      RRID:AB_2067762

      DOI: 10.1016/j.xgen.2022.100095

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      Curator: @sophiastull

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    2. scibot 11 Feb 2022
      RRID:AB_2067762

      DOI: 10.1016/j.xgen.2022.100095

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S2666979X2200012X
  24. Nov 2021
  25. www.sciencedirect.com www.sciencedirect.com
    A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization
    1
    1. scibot 18 Nov 2021
      RRID:AB_2067762

      DOI: 10.1016/j.molcel.2021.10.017

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    sciencedirect.com/science/article/pii/S1097276521009096
  26. Oct 2021
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination
    1
    1. scibot 28 Oct 2021
      RRID:AB_2067762

      DOI: 10.1038/s41467-021-26079-0

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8484605/
  28. Sep 2021
  29. www.sciencedirect.com www.sciencedirect.com
    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
    1
    1. scibot 11 Sep 2021
      RRID:AB_2067762

      DOI: 10.1016/j.molcel.2021.08.016

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

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    sciencedirect.com/science/article/pii/S1097276521006833
  30. Aug 2021
  31. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 10 Aug 2021
      RRID:AB_2067762

      DOI: 10.1016/j.molcel.2018.11.003

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

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    sciencedirect.com/science/article/pii/S1097276518309456
  32. www.sciencedirect.com www.sciencedirect.com
    BRCA2 deficiency reveals that oxidative stress impairs RNaseH1 function to cripple mitochondrial DNA maintenance
    1
    1. scibot 04 Aug 2021
      RRID:AB_2067762

      DOI: 10.1016/j.celrep.2021.109478

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

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    sciencedirect.com/science/article/pii/S2211124721009050
  33. Jun 2021
  34. www.sciencedirect.com www.sciencedirect.com
    RADX prevents genome instability by confining replication fork reversal to stalled forks
    1
    1. scibot 09 Jun 2021
      RRID:AB_2067762

      DOI: 10.1016/j.molcel.2021.05.014

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

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    sciencedirect.com/science/article/pii/S1097276521003907
  35. May 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease
    1
    1. scibot 21 May 2021
      RRID:AB_2067762

      DOI: 10.1016/j.molcel.2021.04.028

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

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    sciencedirect.com/science/article/pii/S1097276521003579
  37. www.sciencedirect.com www.sciencedirect.com
    Homology-directed repair protects the replicating genome from metabolic assaults
    1
    1. scibot 06 May 2021
      RRID:AB_2067762

      DOI: 10.1016/j.devcel.2021.01.011

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S1534580721000691
  38. Jan 2021
  39. www.sciencedirect.com www.sciencedirect.com
    DCAF14 promotes stalled fork stability to maintain genome integrity
    1
    1. scibot 28 Jan 2021
      RRID:AB_2067762

      DOI: 10.1016/j.celrep.2020.108669

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

      Curator: @Naa003

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      RRID:AB_2067762 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720316582
  40. Dec 2020
  41. www.embopress.org www.embopress.org
    Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA
    1
    1. scibot 07 Dec 2020
      anti‐BRCA2

      DOI: 10.15252/embj.2019103654

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2067762

      Curator comments: Anti-BRCA2 (Ab-1) Mouse mAb (2B) antibody Millipore Cat# OP95

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      RRIDCUR:Missing RRID:AB_2067762
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    embopress.org/doi/abs/10.15252/embj.2019103654
  42. Sep 2020
  43. www.sciencedirect.com www.sciencedirect.com
    Systematic Characterization of Recurrent Genomic Alterations in Cyclin-Dependent Kinases Reveals Potential Therapeutic Strategies for Cancer Treatment
    1
    1. scibot 17 Sep 2020
      RRID:AB_2067762

      DOI: 10.1016/j.celrep.2020.107884

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      Curator: @Naa003

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      RRID:AB_2067762 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720308652
  44. www.sciencedirect.com www.sciencedirect.com
    L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis
    1
    1. scibot 06 Sep 2020
      RRID:AB_2067762

      DOI: 10.1016/j.celrep.2020.107974

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

      Curator: @Naa003

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      RRID:AB_2067762 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720309554
  45. Jan 2020
  46. www.sciencedirect.com www.sciencedirect.com
    HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis
    1
    1. scibot 13 Jan 2020
      RRID:AB_2067762

      DOI: 10.1016/j.celrep.2019.05.096

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

      Curator: @ethanbadger

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      RRID:AB_2067762 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719307351
  47. www.sciencedirect.com www.sciencedirect.com
    Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
    1
    1. scibot 13 Jan 2020
      RRID:AB_2067762

      DOI: 10.1016/j.molcel.2019.10.026

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

      Curator: @ethanbadger

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      RRID:AB_2067762 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519308044
  48. www.embopress.org www.embopress.org
    The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8
    1
    1. scibot 13 Jan 2020
      RRID:AB_2067762

      DOI: 10.15252/embj.2019102361

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

      Curator: @Naa003

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      RRID:AB_2067762 RRIDCUR:Validated
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    embopress.org/doi/10.15252/embj.2019102361
  49. www.sciencedirect.com www.sciencedirect.com
    EXD2 Protects Stressed Replication Forks and Is Required for Cell Viability in the Absence of BRCA1/2
    1
    1. scibot 13 Jan 2020
      RRID:AB_2067762

      DOI: 10.1016/j.molcel.2019.05.026

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

      Curator: @ethanbadger

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      RRID:AB_2067762 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519303983
  50. www.sciencedirect.com www.sciencedirect.com
    Human RIF1-Protein Phosphatase 1 Prevents Degradation and Breakage of Nascent DNA on Replication Stalling
    1
    1. scibot 13 Jan 2020
      RRID:AB_2067762

      DOI: 10.1016/j.celrep.2019.05.002

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

      Curator: @ethanbadger

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      RRID:AB_2067762 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719306060
  51. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_2067762

      DOI: 10.1016/j.molcel.2018.12.008

      Resource: (Millipore Cat# OP95, RRID:AB_2067762)

      Curator: @ethanbadger

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      RRID:AB_2067762 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276518310621
  52. Nov 2018
  53. www.sciencedirect.com www.sciencedirect.com
    CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress
    1
    1. scibot 05 Nov 2018
      RRID:AB_2067762

      Curator: @Jmenke

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      (Millipore Cat# OP95, RRID:AB_2067762)

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      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2067762 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276518307858
  54. Nov 2017
  55. www.sciencedirect.com www.sciencedirect.com
    RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks
    1
    1. scibot 08 Nov 2017
      AB_2067762

      Curator: @chewbeccax

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      (Millipore Cat# OP95, RRID:AB_2067762)

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      RRID:AB_2067762 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517304574
  56. www.sciencedirect.com www.sciencedirect.com
    A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability
    1
    1. scibot 08 Nov 2017
      AB_2067762

      Curator: @Zeljana_Babic

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      (Millipore Cat# OP95, RRID:AB_2067762)

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      RRID:AB_2067762 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867417305378