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40 Matching Annotations

Last 7 days
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CDT1 acts with the replisome to remodel replication forks

1
1. scibot 20 Aug 2026
  
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  RRID:AB_2067762
  
  DOI: 10.1126/sciadv.aee6914
  
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science.org/doi/10.1126/sciadv.aee6914
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

H2BK120ub and its reader RNF169 sequentially regulate replication fork remodeling and stability

1
1. scibot 20 Nov 2025
  
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  RRID:AB_2067762
  
  DOI: 10.1038/s44318-025-00602-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12623888/
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress

1
1. scibot 14 Aug 2025
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.molcel.2025.07.013
  
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sciencedirect.com/science/article/pii/S1097276525006148
May 2025
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Distinct roles of the two BRCA2 DNA-binding domains in DNA damage repair and replication fork preservation

1
1. scibot 16 May 2025
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.celrep.2025.115654
  
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sciencedirect.com/science/article/pii/S2211124725004255
Mar 2025
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SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair

1
1. scibot 07 Mar 2025
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.molcel.2025.02.004
  
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sciencedirect.com/science/article/pii/S1097276525001091
Feb 2025
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Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors

1
1. scibot 27 Feb 2025
  
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  AB_2067762
  
  DOI: 10.1016/j.molcel.2025.01.031
  
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sciencedirect.com/science/article/pii/S109727652500098X
Sep 2024
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Transient splicing inhibition causes persistent DNA damage and chemotherapy vulnerability in triple-negative breast cancer

1
1. scibot 17 Sep 2024
  
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  AB_2067762
  
  DOI: 10.1016/j.celrep.2024.114751
  
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sciencedirect.com/science/article/pii/S2211124724011021
Aug 2024
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RAD51 protects abasic sites to prevent replication fork breakage

1
1. scibot 23 Aug 2024
  
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  AB_2067762
  
  DOI: 10.1016/j.molcel.2024.07.004
  
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sciencedirect.com/science/article/pii/S109727652400580X
Feb 2024
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Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection

1
1. scibot 23 Feb 2024
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.celrep.2024.113845
  
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sciencedirect.com/science/article/pii/S2211124724001736
Jan 2024
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BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution

1
1. scibot 25 Jan 2024
  
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  RRID: AB_2067762
  
  DOI: 10.1016/j.molcel.2023.12.040
  
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  Curator: @abever99
  
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sciencedirect.com/science/article/pii/S1097276523010869
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EXO1 protects BRCA1-deficient cells against toxic DNA lesions

1
1. scibot 25 Jan 2024
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.molcel.2023.12.039
  
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sciencedirect.com/science/article/pii/S1097276523010857
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms

1
1. scibot 06 Oct 2023
  
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  AB_2067762
  
  DOI: 10.1016/j.celrep.2023.112792
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10529362/
Jul 2023
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Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein

1
1. scibot 27 Jul 2023
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.molcel.2023.06.031
  
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sciencedirect.com/science/article/pii/S1097276523005075
Jun 2023
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FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics

1
1. scibot 23 Jun 2023
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.celrep.2023.112668
  
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sciencedirect.com/science/article/pii/S2211124723006794
Dec 2022
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POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells

1
1. scibot 01 Dec 2022
  
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  RRID:AB_206776
  
  DOI: 10.1016/j.molcel.2022.11.008
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:AB_2067762
  
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  RRIDCUR:Unresolved RRID:AB_2067762
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sciencedirect.com/science/article/pii/S109727652201070X
Sep 2022
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

CANCER-ASSOCIATED SF3B1 MUTATIONS CONFER A BRCA-LIKE CELLULAR PHENOTYPE AND SYNTHETIC LETHALITY TO PARP INHIBITORS

1
1. scibot 02 Sep 2022
  
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  RRID:AB_2067762
  
  DOI: 10.1158/0008-5472.CAN-21-1843
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
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pubmed.ncbi.nlm.nih.gov/35027467/
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells

1
1. scibot 26 Aug 2022
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.molcel.2022.07.011
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
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sciencedirect.com/science/article/pii/S1097276522007079
Feb 2022
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Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy

2
1. scibot 11 Feb 2022
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.xgen.2022.100095
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:AB_2067762
  
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  RRID:AB_2067762
2. scibot 11 Feb 2022
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.xgen.2022.100095
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:AB_2067762
  
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sciencedirect.com/science/article/pii/S2666979X2200012X
Nov 2021
www.sciencedirect.com www.sciencedirect.com

A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization

1
1. scibot 18 Nov 2021
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.molcel.2021.10.017
  
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sciencedirect.com/science/article/pii/S1097276521009096
Oct 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination

1
1. scibot 28 Oct 2021
  
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  RRID:AB_2067762
  
  DOI: 10.1038/s41467-021-26079-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8484605/
Sep 2021
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REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps

1
1. scibot 11 Sep 2021
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.molcel.2021.08.016
  
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sciencedirect.com/science/article/pii/S1097276521006833
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 10 Aug 2021
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.molcel.2018.11.003
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
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sciencedirect.com/science/article/pii/S1097276518309456
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BRCA2 deficiency reveals that oxidative stress impairs RNaseH1 function to cripple mitochondrial DNA maintenance

1
1. scibot 04 Aug 2021
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.celrep.2021.109478
  
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sciencedirect.com/science/article/pii/S2211124721009050
Jun 2021
www.sciencedirect.com www.sciencedirect.com

RADX prevents genome instability by confining replication fork reversal to stalled forks

1
1. scibot 09 Jun 2021
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.molcel.2021.05.014
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
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sciencedirect.com/science/article/pii/S1097276521003907
May 2021
www.sciencedirect.com www.sciencedirect.com

Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease

1
1. scibot 21 May 2021
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.molcel.2021.04.028
  
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sciencedirect.com/science/article/pii/S1097276521003579
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Homology-directed repair protects the replicating genome from metabolic assaults

1
1. scibot 06 May 2021
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.devcel.2021.01.011
  
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sciencedirect.com/science/article/pii/S1534580721000691
Jan 2021
www.sciencedirect.com www.sciencedirect.com

DCAF14 promotes stalled fork stability to maintain genome integrity

1
1. scibot 28 Jan 2021
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.celrep.2020.108669
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2067762
  
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  RRID:AB_2067762 RRIDCUR:Validated
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S2211124720316582
Dec 2020
www.embopress.org www.embopress.org

Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA

1
1. scibot 07 Dec 2020
  
  in Public
  
  anti‐BRCA2
  
  DOI: 10.15252/embj.2019103654
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2067762
  
  Curator comments: Anti-BRCA2 (Ab-1) Mouse mAb (2B) antibody Millipore Cat# OP95
  
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  RRIDCUR:Missing RRID:AB_2067762
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embopress.org/doi/abs/10.15252/embj.2019103654
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Systematic Characterization of Recurrent Genomic Alterations in Cyclin-Dependent Kinases Reveals Potential Therapeutic Strategies for Cancer Treatment

1
1. scibot 17 Sep 2020
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.celrep.2020.107884
  
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  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2067762
  
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  RRID:AB_2067762 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720308652
www.sciencedirect.com www.sciencedirect.com

L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis

1
1. scibot 06 Sep 2020
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.celrep.2020.107974
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2067762
  
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  RRID:AB_2067762 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720309554
Jan 2020
www.sciencedirect.com www.sciencedirect.com

HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.celrep.2019.05.096
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2067762
  
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  RRID:AB_2067762 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719307351
www.sciencedirect.com www.sciencedirect.com

Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.molcel.2019.10.026
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2067762
  
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  RRID:AB_2067762 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519308044
www.embopress.org www.embopress.org

The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2067762
  
  DOI: 10.15252/embj.2019102361
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2067762
  
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  RRID:AB_2067762 RRIDCUR:Validated
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embopress.org/doi/10.15252/embj.2019102361
www.sciencedirect.com www.sciencedirect.com

EXD2 Protects Stressed Replication Forks and Is Required for Cell Viability in the Absence of BRCA1/2

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.molcel.2019.05.026
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2067762
  
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  RRID:AB_2067762 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519303983
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Human RIF1-Protein Phosphatase 1 Prevents Degradation and Breakage of Nascent DNA on Replication Stalling

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.celrep.2019.05.002
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124719306060
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_2067762
  
  DOI: 10.1016/j.molcel.2018.12.008
  
  Resource: (Millipore Cat# OP95, RRID:AB_2067762)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1097276518310621
Nov 2018
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CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress

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1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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Nov 2017
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RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks

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1. scibot 08 Nov 2017
  
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  AB_2067762
  
  Curator: @chewbeccax
  
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A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability

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1. scibot 08 Nov 2017
  
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  AB_2067762
  
  Curator: @Zeljana_Babic
  
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sciencedirect.com/science/article/pii/S0092867417305378