57 Matching Annotations
  1. May 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Triptolide enhances anti-cancer activities of irinotecan in human colon cancer HT-29 cells in vitro and HT-29 cell xenograft tumor model in nude mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13201951/
  3. Feb 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Unified modeling of 3D molecular generation via atomic interactions with PocketXMol
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    sciencedirect.com/science/article/pii/S0092867426000504
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Raspberry Polyphenols Target Molecular Pathways of Heart Failure
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    pmc.ncbi.nlm.nih.gov/articles/PMC12862629/
  6. Sep 2025
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    Pharmacological and toxicological profiling of JAMC-4/108: targeted induction of apoptosis in human colorectal cancer cells
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    sciencedirect.com/science/article/pii/S0022356525402407
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatiotemporal differential regulation of extrasynaptic GluN2B receptor subunits and PSA-NCAM in brain aging and Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12426952/
  9. Jun 2025
  10. www.cell.com www.cell.com
    BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival
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    cell.com/molecular-cell/fulltext/S1097-2765(25)00499-X
  11. Apr 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated pharmacoanalysis, bioinformatics analysis, and experimental validation to identify the ingredients and mechanisms of Xiao-Luo-Wan in uterine fibroids treatment
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    pmc.ncbi.nlm.nih.gov/articles/PMC11999358/
  13. Feb 2025
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    Microglial pyroptosis drives neuropathic pain and targeting NLRP3 alleviates pain and neuroinflammation
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    sciencedirect.com/science/article/pii/S0925443925000821
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    Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1535610825000224
  16. Jan 2025
  17. www.sciencedirect.com www.sciencedirect.com
    Muscle-derived small extracellular vesicles induce liver fibrosis during overtraining
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    sciencedirect.com/science/article/pii/S1550413124004881
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Arginase Activity Inhibition With Thymoquinone Induces a Hybrid Type of Cell‐Death in MDA‐MB‐231 Cell Line
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    pmc.ncbi.nlm.nih.gov/articles/PMC11744436/
  19. Dec 2024
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fingolimod Inhibits C6 Rat Glioma Proliferation and Migration, Induces Sub-G1 Cell Cycle Arrest, Mitochondrial and Extrinsic Apoptosis In Vitro and Reduces Tumour Growth In Vivo
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    onlinelibrary.wiley.com/doi/10.1111/1440-1681.70012
  21. Oct 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application
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    ncbi.nlm.nih.gov/pmc/articles/PMC11427689/
  23. Jul 2024
  24. www.cell.com www.cell.com
    Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK
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    cell.com/cell-host-microbe/fulltext/S1931-3128(24)00254-3
  25. www.cell.com www.cell.com
    Eupalinolide B suppresses pancreatic cancer by ROS generation and potential cuproptosis
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    cell.com/iscience/fulltext/S2589-0042(24)01721-8
  26. www.biorxiv.org www.biorxiv.org
    Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor
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    biorxiv.org/content/10.1101/2024.06.11.598518v2
  27. May 2024
  28. www.sciencedirect.com www.sciencedirect.com
    Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia
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    sciencedirect.com/science/article/pii/S2211124724005655
  29. Mar 2024
  30. www.sciencedirect.com www.sciencedirect.com
    A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis
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    sciencedirect.com/science/article/pii/S2211124724003322
  31. Feb 2024
  32. link.springer.com link.springer.com
    CircUSP1 as a novel marker promotes gastric cancer progression via stabilizing HuR to upregulate USP1 and Vimentin
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    link.springer.com/article/10.1038/s41388-024-02968-8
  33. Dec 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Design, synthesis and mechanistic anticancer activity of new acetylated 5-aminosalicylate-thiazolinone hybrid derivatives
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    sciencedirect.com/science/article/pii/S2589004223027360
  35. Nov 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10629731/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRL2 inhibition elevates PTEN protein and ameliorates progression of acute myeloid leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10619439/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of lysosome-tethered Ragulator-Rag-3D complex restricts the replication of Enterovirus 71 and Coxsackie A16
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    ncbi.nlm.nih.gov/pmc/articles/PMC10619577/
  39. Sep 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aggravated hepatic fibrosis induced by phenylalanine and tyrosine was ameliorated by chitooligosaccharides supplementation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10507131/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    URAT1 is expressed in cardiomyocytes and dotinurad attenuates the development of diet-induced metabolic heart disease.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10483053/
  42. Aug 2023
  43. 52.53.155.43 52.53.155.43
    ioad093-html.html
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  44. Feb 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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    sciencedirect.com/science/article/pii/S2589004223002468
  46. Jan 2023
  47. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    P38γ modulates the lipid metabolism in non-alcoholic fatty liver disease by regulating the JAK–STAT signaling pathway
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202200939RR
  48. Dec 2022
  49. www.science.org www.science.org
    Gasdermins and pannexin-1 mediate pathways of chemotherapy-induced cell lysis in hematopoietic malignancies
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    science.org/doi/10.1126/scisignal.abl6781
  50. link.springer.com link.springer.com
    Celecoxib activates autophagy by inhibiting the mTOR signaling pathway and prevents apoptosis in nucleus pulposus cells
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    link.springer.com/article/10.1186/s40360-022-00633-y
  51. Jul 2022
  52. link.springer.com link.springer.com
    Transmissible ER stress between macrophages and tumor cells configures tumor microenvironment
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    link.springer.com/article/10.1007/s00018-022-04413-z
  53. Jun 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Progesterone limits the tumor-promoting effects of the beta-subunit of human chorionic gonadotropin via non-nuclear receptors
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    sciencedirect.com/science/article/pii/S2589004222007982
  55. academic.oup.com academic.oup.com
    Deficiency of C1QL1 reduced murine ovarian follicle reserve through intraovarian and endocrine control
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    academic.oup.com/endo/article/163/6/bqac048/6569208
  56. May 2022
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide
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    onlinelibrary.wiley.com/doi/10.1002/jbt.23099
  58. Apr 2022
  59. link.springer.com link.springer.com
    Energetic metabolic reprogramming in Jurkat DFF40-deficient cancer cells
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    link.springer.com/article/10.1007/s11010-022-04433-0
  60. www.sciencedirect.com www.sciencedirect.com
    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
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    sciencedirect.com/science/article/pii/S0092867422003403
  61. Mar 2022
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Poly (ADP-ribose) polymerase 1-mediated defective mitophagy contributes to painful diabetic neuropathy in the db/db model
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15606
  63. www.sciencedirect.com www.sciencedirect.com
    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S1550413122000547
  64. journals.lww.com journals.lww.com
    MicroRNA-101a-3p mimic ameliorates spinal cord... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2022/17090/MicroRNA_101a_3p_mimic_ameliorates_spinal_cord.34.aspx
  65. Feb 2022
  66. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
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    pubmed.ncbi.nlm.nih.gov/35139355/
  67. Sep 2021
  68. www.sciencedirect.com www.sciencedirect.com
    Roles of autophagy in relation to mitochondrial stress responses of HeLa cells to lamellarin cytotoxicity
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    sciencedirect.com/science/article/pii/S0300483X21002857
  69. Aug 2021
  70. www.sciencedirect.com www.sciencedirect.com
    The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway
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    sciencedirect.com/science/article/pii/S2211383521003051
  71. Jul 2021
  72. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Japanese Encephalitis Virus‐induced let‐7a/b interacted with the NOTCH‐TLR7 pathway in microglia and facilitated neuronal death via caspase activation
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14645
  73. rupress.org rupress.org
    Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination
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    rupress.org/jcb/article/220/6/e202006043/211984/Parkin-independent-mitophagy-via-Drp1-mediated
  74. Jun 2021
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC8201054/
  76. Apr 2021
  77. www.sciencedirect.com www.sciencedirect.com
    Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition
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    sciencedirect.com/science/article/pii/S1550413120306537
  78. www.sciencedirect.com www.sciencedirect.com
    Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases
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    sciencedirect.com/science/article/pii/S2211124721003120
  79. Sep 2020
  80. www.sciencedirect.com www.sciencedirect.com
    A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling
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    sciencedirect.com/science/article/pii/S2211124720303442
  81. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14957
  82. Jan 2020
  83. www.sciencedirect.com www.sciencedirect.com
    Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles
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    sciencedirect.com/science/article/pii/S2211124719306199
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    bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14773
  85. journals.plos.org journals.plos.org
    Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer’s mouse model are associated with hippocampal synaptic deficits in an age-dependent manner
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    journals.plos.org/plosone/article
  86. Nov 2018
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC6232850/
  88. Nov 2017
  89. www.sciencedirect.com www.sciencedirect.com
    Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages
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    sciencedirect.com/science/article/pii/S2451945617300922