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    Metformin dual-targets metabolism and survival pathways in BPDCN
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    sciencedirect.com/science/article/pii/S2589004226016986
  3. Dec 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anti-Cancer Effects of the Ethyl Acetate Fraction From Opuntia humifusa on Human Triple-Negative Breast Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12705953/
  5. Nov 2025
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    Novel compounds with promising HuH-7 inhibitory activity as new cancer drug candidates: derivatives of N,N′-diphenylurea linked with 1,2,3-triazole
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    tandfonline.com/doi/abs/10.1080/14756366.2025.2585597
  7. Oct 2025
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    Catenibacterium mitsuokai promotes hepatocellular carcinogenesis by binding to hepatocytes and generating quinolinic acid
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    sciencedirect.com/science/article/pii/S1550413125003869
  9. Aug 2025
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    Dapk2 dysfunction leads to Mic60 lactylation and mitochondrial metabolic reprogramming, promoting lung cancer EGFR-TKI resistance and metastasis
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    sciencedirect.com/science/article/pii/S153458072500471X
  11. Jul 2025
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    Targeting the WSB2–NOXA axis in cancer cells for enhanced sensitivity to BCL-2 family protein inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12286604/
  13. Jun 2025
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    Cisplatin-Induced APE2 Overexpression Disrupts MYH9 Function and Causes Hearing Loss
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    Holothurian Glycosaminoglycan (hGAG) Promoted Bim-Induced Apoptosis in Human Lung Adenocarcinoma A549 Cell Line Through Inhibition of Akt-Mediated FOXO3a Translocation
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    journals.sagepub.com/doi/full/10.1177/15347354251341442
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    Holothurian Glycosaminoglycan (hGAG) Promoted Bim-Induced Apoptosis in Human Lung Adenocarcinoma A549 Cell Line Through Inhibition of Akt-Mediated FOXO3a Translocation
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  18. May 2025
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    Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity
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  20. Jun 2024
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    Insulin reduces endoplasmic reticulum stress‐induced apoptosis by decreasing mitochondrial hyperpolarization and caspase‐12 in INS‐1 pancreatic β‐cells
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  22. May 2024
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    Imipridones inhibit tumor growth and improve survival in an orthotopic liver metastasis mouse model of human uveal melanoma
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  24. Apr 2024
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    Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
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  26. Nov 2023
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    Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation
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  28. Oct 2023
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    Breast Cancer Cells are Sensitized by Piperine to Radiotherapy through Estrogen Receptor-α mediated modulation of a Key NHEJ repair protein- DNA-PK
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    sciencedirect.com/science/article/pii/S0944711323004865
  30. May 2023
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    Tumor treating fields affect mesothelioma cell proliferation by exerting histotype-dependent cell cycle checkpoint activations and transcriptional modulations
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  33. Feb 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of iNOS/NO Promotes Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer
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  35. Jan 2023
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    Decitabine enhances the tumoricidal potential of TRAIL via the epigenetic regulation of death receptor 4 in gastric cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9830339/
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    Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe2+ pathways
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    Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome
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  39. Nov 2022
  40. academic.oup.com academic.oup.com
    Inhibition of Glycogen Metabolism Induces Reactive Oxygen Species-Dependent Cytotoxicity in Anaplastic Thyroid Cancer in Female Mice
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  41. Sep 2022
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    Sublethal cytochrome c release generates drug-tolerant persister cells
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  43. Mar 2022
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    Pathogen hijacks programmed cell death signaling by arginine ADPR-deacylization of caspases
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  45. Feb 2022
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T63 induces apoptosis in nasopharyngeal carcinoma cells through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC8797319/
  47. Dec 2021
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of RIPK1 in SMAC mimetics-induced apoptosis in primary human HIV-infected macrophages
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    ncbi.nlm.nih.gov/pmc/articles/PMC8617210/
  49. Nov 2021
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    Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery
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  51. Aug 2021
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  53. Jul 2021
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  55. Mar 2021
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  57. Jan 2021
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15306
  59. Sep 2020
  60. link.springer.com link.springer.com
    Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells
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    link.springer.com/article/10.1186/s13148-020-00839-z
  61. Jan 2020
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Specific Inhibition of SOD1 Selectively Promotes Apoptosis of Cancer Cells via Regulation of the ROS Signaling Network
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    ncbi.nlm.nih.gov/pmc/articles/PMC6398008/
  63. mbio.asm.org mbio.asm.org
    TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function
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    21-benzylidene digoxin decreases proliferation by inhibiting the egfr/erk signaling pathway and induces apoptosis in hela cells
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    sciencedirect.com/science/article/pii/S0039128X19302417
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    Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover
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    Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers
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    sciencedirect.com/science/article/pii/S2211124719309672
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    Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-Akt1 Complex Modulates Glioblastoma Therapy Sensitivity
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  68. Nov 2018
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    Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death
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    sciencedirect.com/science/article/pii/S2451945618301855
  70. Nov 2017
  71. journals.plos.org journals.plos.org
    Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival
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    journals.plos.org/plosone/article