535 Matching Annotations
  1. Apr 2024
  2. 52.53.155.43 52.53.155.43
    TSPYL2 induces renal ischemia-reperfusion injury through SREBP-2/ACMSD signaling
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    1. scibot 11 Apr 2024
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    52.53.155.43/6757b9d9d924ce64a3f7cf8064c4794b752c3bb9/1-s2.0-S2589004224008162-main-html.html
  3. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 11 Apr 2024
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      DOI: 10.1111/bph.16364

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16364
  4. www.sciencedirect.com www.sciencedirect.com
    Glutamatergic neuronal activity regulates angiogenesis and blood-retinal barrier maturation via Norrin/β-catenin signaling
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    1. scibot 10 Apr 2024
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      DOI: 10.1016/j.neuron.2024.03.011

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    sciencedirect.com/science/article/pii/S089662732400165X
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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    1. scibot 10 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11000015/
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    Oct4 controls basement membrane development during human embryogenesis
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    1. scibot 05 Apr 2024
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    sciencedirect.com/science/article/pii/S1534580724001758
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
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    1. scibot 03 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10592192/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NSAID targets SIRT3 to trigger mitochondrial dysfunction and gastric cancer cell death
    1
    1. scibot 03 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10972828/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Omics Analysis Identifies CCR6 as a Therapeutic Target to Overcome Cancer Resistance to EGFR Inhibitors
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    1. scibot 03 Apr 2024
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  10. Mar 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
    1
    1. scibot 27 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10960275/
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    FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis
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    1. scibot 22 Mar 2024
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    sciencedirect.com/science/article/pii/S1097276524001801
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    SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis
    2
    1. scibot 22 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724003036
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    A humoral stress response protects Drosophila tissues from antimicrobial peptides
    1
    1. scibot 14 Mar 2024
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    sciencedirect.com/science/article/pii/S096098222400232X
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    PRMT1 promotes pancreatic cancer development and resistance to chemotherapy
    2
    1. scibot 12 Mar 2024
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    sciencedirect.com/science/article/pii/S2666379124001058
  16. 52.53.155.43 52.53.155.43
    JNEUROSCI.1600-23.2024.full-html.html
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    1. scibot 08 Mar 2024
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      DOI: 10.1523/jneurosci.1600-23.2024

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    Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
    2
    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.isci.2024.109219

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    sciencedirect.com/science/article/pii/S2589004224004401
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    Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
    2
    1. scibot 06 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724002031
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1158/1535-7163.MCT-23-0025

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527992/
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    Identification and characterization of a potent and selective HUNK inhibitor for treatment of HER2+ breast cancer
    1
    1. scibot 06 Mar 2024
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    sciencedirect.com/science/article/pii/S2451945624000370
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Highlights from MBoC Selection: Preexisting tissue mechanical hypertension at adherens junctions disrupts apoptotic extrusion in epithelia
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      DOI: 10.1091/mbc.E23-08-0337

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    ncbi.nlm.nih.gov/pmc/articles/PMC10881161/
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    Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
    3
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      DOI: 10.1016/j.ccell.2024.02.004

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    sciencedirect.com/science/article/pii/S1535610824000485
  23. Feb 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the Wnt/β-catenin/CYP1B1 pathway alleviates oxidative stress and protects the blood-brain barrier under cerebral ischemia/reperfusion conditions
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    1. scibot 28 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10883507/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a First-in-Class Small Molecule Inhibitor of the eIF4E-RBM38 Complex that Enhances wild-type p53 Protein Translation for Tumor Growth Suppression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10866396/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Temozolomide sensitizes ARID1A-mutated cancers to PARP inhibitors
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      DOI: 10.1158/0008-5472.CAN-22-3646

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527942/
  27. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 16 Feb 2024
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      DOI: 10.1111/bph.16283

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16283
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gut-Brain Axis Interplay via STAT3 pathway: Implications of Helicobacter pylori derived secretome on inflammation and Alzheimer's disease
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      DOI: 10.1080/21505594.2024.2303853

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    ncbi.nlm.nih.gov/pmc/articles/PMC10854367/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo
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      DOI: 10.1126/sciadv.adk1835

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    ncbi.nlm.nih.gov/pmc/articles/PMC10866549/
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    Sleep fragmentation induces heart failure in a hypertrophic cardiomyopathy mouse model by altering redox metabolism
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    sciencedirect.com/science/article/pii/S2589004224002967
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    p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
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    sciencedirect.com/science/article/pii/S2666379124000107
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    Melatonin ameliorates retinal ganglion cell senescence and apoptosis in a SIRT1-dependent manner in an optic nerve injury model
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    sciencedirect.com/science/article/pii/S0925443924000425
  33. Jan 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lethal severe fever with thrombocytopenia syndrome virus infection causes systemic germinal centre failure and massive T cell apoptosis in cats
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    ncbi.nlm.nih.gov/pmc/articles/PMC10796997/
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    A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS
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      DOI: 10.1016/j.stem.2023.11.011

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    sciencedirect.com/science/article/pii/S1934590923004113
  36. www.jneurosci.org www.jneurosci.org
    Cleavage of VAMP2/3 Affects Oligodendrocyte Lineage Development in the Developing Mouse Spinal Cord
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      DOI: 10.1523/JNEUROSCI.2206-21.2023

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    jneurosci.org/content/43/39/6592
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    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
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    sciencedirect.com/science/article/pii/S2211124723016376
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    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
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    Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
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    A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS
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    Histone Deacetylase Inhibitors Prevent Cytokine-Induced β Cell Dysfunction Through Restoration of Stromal Interaction Molecule 1 Expression and Activation of Store-Operated Calcium Entry
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    HAMSAB diet ameliorates dysfunctional signaling in pancreatic islets in autoimmune diabetes
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    NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62
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    The Crucial Role of Single-Stranded DNA Binding in Enhancing Sensitivity to DNA-Damaging Agents for Schlafen 11 and Schlafen 13
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    The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
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    B3GALT6 promotes dormant breast cancer cell survival and recurrence by enabling heparan sulfate-mediated FGF signaling
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    Airway epithelial cells and macrophages trigger IL-6-CD95/CD95L axis and mediate initial immunopathology of COVID-19
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    Evolutionary diversification reveals distinct somatic versus germline cytoskeletal functions of the Arp2 branched actin nucleator protein
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    Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities
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    HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B
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    γ-radiation-induced damage on normal hepatocytes and its protection by ethyl cinnamate
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    Combination drug screen targeting glioblastoma core vulnerabilities reveals pharmacological synergisms
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    Caffeine supplementation and FOXM1 inhibition enhance the antitumor effect of statins in neuroblastoma
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    Tyrosine Kinase Inhibitors Diminish Renal Neoplasms in a Tuberous Sclerosis Model via induction of Apoptosis
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    Fancm has dual roles in the limiting of meiotic crossovers and germ cell maintenance in mammals
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    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
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    RORψt+CD4+ T cells promote IL-23R-mediated neuronal cell apoptosis in the central nervous system
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  108. May 2023
  109. www.embopress.org www.embopress.org
    Phospholipid scramblase Xkr8 is required for developmental axon pruning via phosphatidylserine exposure
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    Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin
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    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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    Beclin-1-dependent autophagy, but not apoptosis, is critical for stem-cell-mediated endometrial programming and the establishment of pregnancy
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    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF2
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    Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
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    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel B7-H6–Targeted IgG-Like T Cell–Engaging Antibody for the Treatment of Gastrointestinal Tumors
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    SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
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    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
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  152. Nov 2022
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  163. Oct 2022
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  168. Sep 2022
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