810 Matching Annotations
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    Combination AURKA and WEE1 Inhibition Exhibits Efficacy in EGFR or Pan-ERBB Inhibitor–Resistant Head and Neck Squamous Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13489673/
  3. Aug 2026
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    Stress granules confer an early vulnerability in KRAS-driven pancreatic tumorigenesis
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    A macrophage-intestinal organoid co-culture model captures balanced epithelial homeostasis and inflammation
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    Metabolic atlas of early human cortex reveals glycolytic remodeling and pentose phosphate pathway control of cell fate transitions
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    Circulating cochlin LCCL domain binds to dying cells and enhances efferocytosis
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    Genotoxic antibody-drug conjugates combined with BCL-XL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    Three Thiol-Reactive Reagents drive Synergistic Lethality in Glioblastoma cells
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    Sumoylation profiles and mitochondrial dynamics in in vivo and in vitro models of Parkinson’s disease
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    Glycolytic reprogramming and the EMT drive cervical cancer progression via the NQO1/HIF1α-SIX1 axis
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  13. Jul 2026
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    GBP6 maintains mitochondrial bioenergetics to promote immune evasion from NK cells in cervical cancer
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    Nilotinib induces immunogenic cuproptosis to potentiate cancer immunotherapy
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    Reactive oxygen species stimulate Paneth cell plasticity and diminish antimicrobial function
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    Viral protease-initiated lytic cell death as a universal antiviral mRNA therapy
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    Sevoflurane ameliorates cerebral ischemia–reperfusion injury by modulating mitochondrial dynamics and attenuating apoptosis via Shh-YAP1 signaling pathway
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    TGF-β signaling promotes astroglial activation and TDP-43 proteinopathy in organoid models of frontotemporal lobar degeneration
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    ATM Deficiency Induces TGFβ-Mediated Stromal Programming in Pancreatic Cancer
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    Targeting the αvβ5 Integrin Modifies the TGF-β-Rich Tumor Microenvironment of Pancreatic Cancer
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    HPV E5 Mediates Resistance to Chemotherapy and Radiation by Promoting a Stem Cell-Like Phenotype in Head and Neck Squamous Cell Carcinoma
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    Amphiregulin-mediated EGFR activation drives both intrinsic and acquired resistance to KRAS G12C inhibitors in KRAS G12C–mutant non-small cell lung cancer
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    Supra-additive neuroprotective effects of berberine–metformin combination in diabetic encephalopathy: Chou–Talalay synergy quantification, AMPK–Nrf2 axis modulation, and pharmacokinetic verification
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  30. Jun 2026
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    Identification of FXYD5 as an oncogene in pediatric papillary thyroid cancer
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  37. May 2026
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    Hyperactivated glycolysis drives spatially patterned Kupffer cell depletion in MASLD
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  42. Apr 2026
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    QW-5-70 targets the colchicine site and demonstrates antitumor activity in P-gp–overexpressing cancer models
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    P21-positive senescent stromal cells promote prostate cancer immune suppression and progression that can be reversed by senolytic therapy
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    AMBRA1 enhances Sonic Hedgehog signaling during cerebellar development and in medulloblastoma
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    PTEN loss drives B7H3 upregulation via the mTORC2/FOXO/c-Myc axis to promote tumor immune escape in ovarian cancer
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    The Combination of a BCL-xL PROTAC and an mTOR Inhibitor Sensitizes Pancreatic Ductal Adenocarcinoma to KRASG12D Inhibitor Treatment
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  62. Mar 2026
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    Targeting the RXR Pathway for the Prevention of Triple-Negative Breast Cancer
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    Mapping Intestinal Paracellular Perm Eability in Mice: Regional and Cellular Variability Under Physiological and Stimulated Conditions
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    DCPS modulates TDP-43-linked neurodegeneration through P-body-mediated RNA decay
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  71. Feb 2026
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    Induction of neurodegeneration in the hippocampus of senescence-accelerated mouse-prone 8 (SAMP8) mice by blood-brain barrier-crossing serum amyloid P component
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    Integrative CRISPR Screening and RNA Analyses Discover an Essential Role for PUF60 Interactions with 3' Splice Sites in Cancer Progression
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    Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition
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    Pharmacokinetic-pharmacodynamic-efficacy modeling of the MDM2 inhibitor brigimadlin in glioblastoma patient-derived xenografts
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    Targeting and dissociating HIF2α from the molecular chaperone Hsp70 triggers apoptosis in kidney cancer
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    The Microbial Bile Acid Metabolite 3-oxo-LCA Inhibits Colorectal Cancer Progression
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    Luteolin mitigates inflammatory organ injury by targeting XIAP to block PANoptosis and mitochondrial dysfunction
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    Targeting ATR signaling in sarcoma with homologous recombination deficiency
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    Repression of RIPK1 kinase by INPP5D inhibits expression of diverse proinflammatory mediators and late-onset Alzheimer’s disease risk factors
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  86. Jan 2026
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Thimerosal Inhibits Tumor Malignant Progression through Direct Action and Enhancing the Efficacy of PD-1-Based Immunotherapy
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    Pyroptosis modulates multiple immune cell populations in targeted therapy–treated melanoma
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    SNAP23 deficiency triggers Trim21 mitochondrial translocation to suppress TFAM-mediated oxidative metabolism and drive chemoresistance in colorectal cancer
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    Impaired PARP1-dependent DNA repair in MORC2 mutations drives axonal degeneration in Charcot-Marie-Tooth disease subtype 2Z and spinal muscular atrophy-like neuromotor disorders
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    KDM7B-mediated demethylation of RNF113A regulates small cell lung cancer sensitivity to alkylation damage
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  185. Apr 2025
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  201. Mar 2025
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  213. Feb 2025
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