535 Matching Annotations
  1. May 2022
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A myosin chaperone, UNC-45A, is a novel regulator of intestinal epithelial barrier integrity and repair
    1
    1. scibot 05 May 2022
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      DOI: 10.1096/fj.202200154R

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    ncbi.nlm.nih.gov/pmc/articles/PMC9044500/
  3. www.tandfonline.com www.tandfonline.com
    Akt pathway activation reduces platelet apoptosis and contributes to the increase of platelet counts in solid tumor patients
    1
    1. scibot 01 May 2022
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      DOI: 10.1080/09537104.2022.2026908

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  4. Apr 2022
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epidermal growth factor deficiency predisposes to progressive renal disease
    1
    1. scibot 30 Apr 2022
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      DOI: 10.1096/fj.202101837R

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    ncbi.nlm.nih.gov/pmc/articles/PMC9185668/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcription factors AP-2α and AP-2β regulate distinct segments of the distal nephron in the mammalian kidney
    1
    1. scibot 29 Apr 2022
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      DOI: 10.1038/s41467-022-29644-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC9038906/
  7. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 28 Apr 2022
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      DOI: 10.1111/bph.15837

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15837
  8. www.sciencedirect.com www.sciencedirect.com
    Betacellulin promotes tumor development and EGFR mutant lung cancer growth by stimulating the EGFR pathway and suppressing apoptosis
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    1. scibot 26 Apr 2022
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      DOI: 10.1016/j.isci.2022.104211

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    sciencedirect.com/science/article/pii/S2589004222004813
  9. www.sciencedirect.com www.sciencedirect.com
    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
    1
    1. scibot 21 Apr 2022
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      DOI: 10.1016/j.cell.2022.03.030

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    sciencedirect.com/science/article/pii/S0092867422003403
  10. Mar 2022
  11. www.sciencedirect.com www.sciencedirect.com
    PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade
    1
    1. scibot 30 Mar 2022
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    sciencedirect.com/science/article/pii/S2211124722003266
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    Indirubin-3’-monoxime acts as proteasome inhibitor: Therapeutic application in multiple myeloma
    1
    1. scibot 27 Mar 2022
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      DOI: 10.1016/j.ebiom.2022.103950

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    sciencedirect.com/science/article/pii/S2352396422001347
  13. www.sciencedirect.com www.sciencedirect.com
    Caveolin-1 Peptide Regulates p53-microRNA-34a Feedback in Fibrotic Lung Fibroblasts
    1
    1. scibot 24 Mar 2022
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      DOI: 10.1016/j.isci.2022.104022

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    sciencedirect.com/science/article/pii/S2589004222002929
  14. journals.lww.com journals.lww.com
    Urolithin A alleviates blood-brain barrier disruption and... : Neural Regeneration Research
    1
    1. scibot 10 Mar 2022
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      DOI: 10.4103/1673-5374.335163

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    journals.lww.com/nrronline/Fulltext/2022/17090/Urolithin_A_alleviates_blood_brain_barrier.32.aspx
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    In vivo imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/β-catenin activation
    1
    1. scibot 09 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110461

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    sciencedirect.com/science/article/pii/S2211124722001887
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    Tumor-derived Jagged1 promotes cancer progression through immune evasion
    1
    1. scibot 09 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110492

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    sciencedirect.com/science/article/pii/S221112472200225X
  17. www.sciencedirect.com www.sciencedirect.com
    Tertiary lymphoid structures generate and propagate anti-tumor antibody-producing plasma cells in renal cell cancer
    2
    1. scibot 02 Mar 2022
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      DOI: 10.1016/j.immuni.2022.02.001

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      DOI: 10.1016/j.immuni.2022.02.001

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    sciencedirect.com/science/article/pii/S1074761322000814
  18. www.sciencedirect.com www.sciencedirect.com
    Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin
    1
    1. scibot 02 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110441

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    sciencedirect.com/science/article/pii/S2211124722001681
  19. www.sciencedirect.com www.sciencedirect.com
    Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord
    1
    1. scibot 02 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110423

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    sciencedirect.com/science/article/pii/S2211124722001474
  20. Feb 2022
  21. www.tandfonline.com www.tandfonline.com
    Akt pathway activation reduces platelet apoptosis and contributes to the increase of platelet counts in solid tumor patients
    1
    1. scibot 21 Feb 2022
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    tandfonline.com/doi/full/10.1080/09537104.2022.2026908
  22. www.sciencedirect.com www.sciencedirect.com
    Inactivation of mouse transmembrane prolyl 4-hydroxylase increases blood brain barrier permeability and ischemia-induced cerebral neuroinflammation
    1
    1. scibot 13 Feb 2022
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      DOI: 10.1016/j.jbc.2022.101721

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    sciencedirect.com/science/article/pii/S0021925822001612
  23. www.sciencedirect.com www.sciencedirect.com
    Generation of human induced pluripotent stem cell-derived cerebral organoids for cellular and molecular characterization
    2
    1. scibot 11 Feb 2022
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      DOI: 10.1016/j.xpro.2022.101173

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      DOI: 10.1016/j.xpro.2022.101173

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    sciencedirect.com/science/article/pii/S2666166722000533
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    DsbA-L interacts with VDAC1 in mitochondrion-mediated tubular cell apoptosis and contributes to the progression of acute kidney disease
    2
    1. scibot 11 Feb 2022
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      DOI: 10.1016/j.ebiom.2022.103859

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    2. scibot 09 Feb 2022
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      DOI: 10.1016/j.ebiom.2022.103859

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    sciencedirect.com/science/article/pii/S2352396422000433
  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mechanism of anti-inflammatory effects of Rifampicin in an ex vivo culture system of Hidradenitis Suppurativa
    1
    1. scibot 04 Feb 2022
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      DOI: 10.1111/exd.14531

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    onlinelibrary.wiley.com/doi/10.1111/exd.14531
  26. www.sciencedirect.com www.sciencedirect.com
    Small-molecule inhibitors of ferrochelatase are antiangiogenic agents
    1
    1. scibot 02 Feb 2022
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      DOI: 10.1016/j.chembiol.2022.01.001

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    sciencedirect.com/science/article/pii/S2451945622000010
  27. Jan 2022
  28. link.springer.com link.springer.com
    The cross-talk between Bax, Bcl2, caspases, and DNA damage in bystander HepG2 cells is regulated by γ-radiation dose and time of conditioned media transfer
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      DOI: 10.1007/s10495-022-01713-4

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    link.springer.com/article/10.1007/s10495-022-01713-4
  29. www.sciencedirect.com www.sciencedirect.com
    A stress-reduced passaging technique improves the viability of human pluripotent cells
    1
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      DOI: 10.1016/j.crmeth.2021.100155

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    sciencedirect.com/science/article/pii/S2667237521002320
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disrupted Association of Sensory Neurons With Enveloping Satellite Glial Cells in Fragile X Mouse Model
    1
    1. scibot 20 Jan 2022
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      DOI: 10.3389/fnmol.2021.796070

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    ncbi.nlm.nih.gov/pmc/articles/PMC8763968/
  31. www.sciencedirect.com www.sciencedirect.com
    Adaptive differentiation promotes intestinal villus recovery
    1
    1. scibot 11 Jan 2022
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      DOI: 10.1016/j.devcel.2021.12.012

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    sciencedirect.com/science/article/abs/pii/S1534580721010327
  32. Dec 2021
  33. mct.aacrjournals.org mct.aacrjournals.org
    Antibody-drug conjugate efficacy in neuroblastoma - role of payload, resistance mechanisms, target density, and antibody internalization
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      DOI: 10.1158/1535-7163.MCT-20-1034

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    mct.aacrjournals.org/content/20/11/2228
  34. www.sciencedirect.com www.sciencedirect.com
    Dynamic stem cell selection safeguards the genomic integrity of the epidermis
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      DOI: 10.1016/j.devcel.2021.11.018

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    sciencedirect.com/science/article/pii/S1534580721009424
  35. www.thieme-connect.com www.thieme-connect.com
    Impact of Prematurity on the Buccal Epithelial Cells of the Neonates via Wnt/Beta-Catenin Signaling Pathway and Apoptosis
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      DOI: 10.1055/s-0041-1740348

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    thieme-connect.com/products/ejournals/html/10.1055/s-0041-1740348
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isoform-specific roles of prolyl hydroxylases in the regulation of pancreatic β-cell function
    1
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      DOI: 10.1210/endocr/bqab226

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    ncbi.nlm.nih.gov/pmc/articles/PMC8643417/
  37. www.sciencedirect.com www.sciencedirect.com
    Calpain-2 regulates hypoxia/HIF-induced plasticity toward amoeboid cancer cell migration and metastasis
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      DOI: 10.1016/j.cub.2021.11.040

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    sciencedirect.com/science/article/pii/S0960982221015992
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    NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis
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      DOI: 10.1016/j.cmet.2021.11.011

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    sciencedirect.com/science/article/pii/S1550413121005398
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    Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer
    1
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      DOI: 10.1016/j.celrep.2021.110069

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    sciencedirect.com/science/article/pii/S2211124721015552
  40. Nov 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Distinct contributions of partial and full EMT to breast cancer malignancy
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      DOI: 10.1016/j.devcel.2021.11.006

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    sciencedirect.com/science/article/pii/S1534580721008911
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    Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery
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      DOI: 10.1016/j.molcel.2021.11.004

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    sciencedirect.com/science/article/pii/S1097276521009540
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting EYA3 in Ewing Sarcoma Retards Tumor Growth and Angiogenesis
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      DOI: 10.1158/1535-7163.MCT-20-0749

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    ncbi.nlm.nih.gov/pmc/articles/PMC8102334/
  44. Oct 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Microglial transcription profiles in mouse and in human are driven by APOE4 and sex
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      DOI: 10.1016/j.isci.2021.103238

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    sciencedirect.com/science/article/pii/S2589004221012062
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    Conditions for maintenance of hepatocyte differentiation and function in 3D cultures
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    1. scibot 29 Oct 2021
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      DOI: 10.1016/j.isci.2021.103235

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    sciencedirect.com/science/article/pii/S2589004221012037
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miR-103-3p targets Ndel1 to regulate neural stem cell proliferation and differentiation
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pathology of nNOS expressing GABAergic neurons in mouse model of Alzheimer’s disease
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  96. academic.oup.com academic.oup.com
    The loss of ARNT/HIF1β in male pancreatic β-cells is protective against high fat diet-induced diabetes
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  97. Jul 2021
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    GX15–070 (Obatoclax), a Bcl-2 family proteins inhibitor engenders apoptosis and pro-survival autophagy and increases Chemosensitivity in neuroblastoma
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      Cleaved Caspase-3

      DOI: 10.1186/s12885-019-6195-y

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  101. academic.oup.com academic.oup.com
    VCAM1 Is Induced in Ovarian Theca and Stromal Cells in a Mouse Model of Androgen Excess
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  102. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fluoxetine and its metabolite norfluoxetine induce microglial apoptosis
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  103. elifesciences.org elifesciences.org
    Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
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      Cleaved caspase-3

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    Systematic spatio‐temporal mapping reveals divergent cell death pathways in three mouse models of hereditary retinal degeneration
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    mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability
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      Cleaved Caspase-3 D175

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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration
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  108. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Norepinephrine protects against apoptosis of mesenchymal stem cells induced by high glucose
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  109. www.sciencedirect.com www.sciencedirect.com
    The NF-κB Factor Relish Regulates Atg1 Expression and Controls Autophagy
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  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  111. www.physiology.org www.physiology.org
    Vitamin D receptor activation protects against lipopolysaccharide-induced acute kidney injury through suppression of tubular cell apoptosis
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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  114. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Japanese Encephalitis Virus‐induced let‐7a/b interacted with the NOTCH‐TLR7 pathway in microglia and facilitated neuronal death via caspase activation
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZPK/DLK and MKK4 Form the Critical Gateway to Axotomy-Induced Motoneuron Death in Neonates
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    Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC
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    A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope
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    An iPSC model of hereditary sensory neuropathy-1 reveals L-serine-responsive deficits in neuronal ganglioside composition and axoglial interactions
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    Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis
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    Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration
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    High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity
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  126. May 2021
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    SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells
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    DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance
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    Alveolar epithelial cell fate is maintained in a spatially restricted manner to promote lung regeneration after acute injury
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    Plasmalogen attenuates the development of hepatic steatosis and cognitive deficit through mechanism involving p75NTR inhibition
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    Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program
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  133. www.sciencedirect.com www.sciencedirect.com
    Control of Glucocorticoid Receptor Levels by PTEN Establishes a Failsafe Mechanism for Tumor Suppression
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    PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression
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    Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG
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    The multitargeted kinase inhibitor KW-2449 ameliorates cisplatin-induced nephrotoxicity by targeting RIPK1-mediated necroptosis
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  150. Mar 2021
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    Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice
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    Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination
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    Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isorhamnetin Inhibits Human Gallbladder Cancer Cell Proliferation and Metastasis via PI3K/AKT Signaling Pathway Inactivation
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  155. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence
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  156. Feb 2021
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    Activation of ovarian taste receptors inhibits progesterone production potentially via NO/cGMP and apoptotic signaling
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    Essential Roles of Tbr1 in the Formation and Maintenance of the Orientation-Selective J-RGCs and a Group of OFF-Sustained RGCs in Mouse
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    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
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    IL-17A Activated by Toll-Like Receptor 9 Contributes to Development of Septic Acute Kidney Injury
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    Generation of a heterozygous C-peptide-mCherry reporter human iPSC line (HMGUi001-A-8)
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      RRID:AB_653551Cell

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    Retinoic acid signalling in fibro/adipogenic progenitors robustly enhances muscle regeneration
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  165. Jan 2021
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    Trophectoderm mechanics direct epiblast shape upon embryo implantation
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    The Integrated UPR and ERAD in Oligodendrocytes Maintain Myelin Thickness in Adults by Regulating Myelin Protein Translation
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  169. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Reprimo-Like Gene Is an Epigenetic-Mediated Tumor Suppressor and a Candidate Biomarker for the Non-Invasive Detection of Gastric Cancer
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  171. www.sciencedirect.com www.sciencedirect.com
    QUAKING Regulates Microexon Alternative Splicing of the Rho GTPase Pathway and Controls Microglia Homeostasis
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  172. Dec 2020
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    Role of VAMP7-Dependent Secretion of Reticulon 3 in Neurite Growth
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    Evaluation of [ 18 F]F-DPA as a target for TSPO in head and neck cancer under normal conditions and after radiotherapy
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  175. www.nature.com www.nature.com
    Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathway
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      RRID:AB_2070042

      DOI: 10.1038/s41467-020-20154-8

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  176. www.sciencedirect.com www.sciencedirect.com
    Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
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      Cleaved caspase 3

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    Reduction of mNAT1/hNAT2 Contributes to Cerebral Endothelial Necroptosis and Aβ Accumulation in Alzheimer’s Disease
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    Effect of Hyperbaric Oxygen Therapy on Acute Liver Injury and Survival in a Rat Cecal Slurry Peritonitis Model
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    Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer
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    Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling
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