535 Matching Annotations
  1. Sep 2020
  2. www.sciencedirect.com www.sciencedirect.com
    Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis
    1
    1. scibot 07 Sep 2020
      RRID:AB_2070042

      DOI: 10.1016/j.immuni.2020.02.007

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    sciencedirect.com/science/article/pii/S1074761320300789
  3. www.sciencedirect.com www.sciencedirect.com
    NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma
    1
    1. scibot 07 Sep 2020
      RRID:AB_2070042

      DOI: 10.1016/j.celrep.2020.107782

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    sciencedirect.com/science/article/pii/S2211124720307622
  4. www.sciencedirect.com www.sciencedirect.com
    Cycling Stem Cells Are Radioresistant and Regenerate the Intestine
    1
    1. scibot 07 Sep 2020
      RRID:AB_2070042

      DOI: 10.1016/j.celrep.2020.107952

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    sciencedirect.com/science/article/pii/S2211124720309335
  5. elifesciences.org elifesciences.org
    Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
    1
    1. scibot 07 Sep 2020
      RRID:AB_2070042

      DOI: 10.7554/eLife.44161

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    elifesciences.org/articles/44161
  6. www.sciencedirect.com www.sciencedirect.com
    An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages
    1
    1. scibot 06 Sep 2020
      RRID:AB_2070042

      DOI: 10.1016/j.celrep.2020.107959

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    sciencedirect.com/science/article/pii/S2211124720309402
  7. www.sciencedirect.com www.sciencedirect.com
    Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage
    1
    1. scibot 06 Sep 2020
      RRID:AB_2070042

      DOI: 10.1016/j.cell.2020.03.052

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    sciencedirect.com/science/article/pii/S0092867420303457
  8. www.cell.com www.cell.com
    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
    1
    1. scibot 05 Sep 2020
      RRID:AB_2070042

      DOI: 10.1016/j.celrep.2020.01.012

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    cell.com/cell-reports/abstract/S2211-1247(20)30021-8
  9. www.mdpi.com www.mdpi.com
    Activins as Dual Specificity TGF-β Family Molecules: SMAD-Activation via Activin- and BMP-Type 1 Receptors
    1
    1. scibot 05 Sep 2020
      RRID:AB_2070042

      DOI: 10.3390/biom10040519

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    mdpi.com/2218-273X/10/4/519
  10. elifesciences.org elifesciences.org
    HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties
    1
    1. scibot 04 Sep 2020
      RRID:AB_2070042

      DOI: 10.7554/eLife.33947

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    elifesciences.org/articles/33947
  11. insight.jci.org insight.jci.org
    The UPR preserves mature oligodendrocyte viability and function in adults by regulating autophagy of PLP
    1
    1. scibot 04 Sep 2020
      cleaved caspase-3

      DOI: 10.1172/jci.insight.132364

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      Curator comments: Cleaved Caspase-3 (Asp175) (5A1E) Rabbit mAb antibody Cell Signaling Technology Cat# 9664

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    insight.jci.org/articles/view/132364
  12. www.sciencedirect.com www.sciencedirect.com
    Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity
    1
    1. scibot 04 Sep 2020
      Cleaved Caspase-3 (Asp175) (5A1E) Rabbit mAb

      DOI: 10.1016/j.cell.2020.02.015

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    sciencedirect.com/science/article/pii/S0092867420301598
  13. www.mdpi.com www.mdpi.com
    Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/β-catenin Signaling
    1
    1. scibot 04 Sep 2020
      caspases-3

      DOI: 10.3390/ijms21051773

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    mdpi.com/1422-0067/21/5/1773
  14. www.sciencedirect.com www.sciencedirect.com
    Apical Restriction of the Planar Cell Polarity Component VANGL in Pancreatic Ducts Is Required to Maintain Epithelial Integrity
    1
    1. scibot 04 Sep 2020
      AB_2070042

      DOI: 10.1016/j.celrep.2020.107677

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    sciencedirect.com/science/article/pii/S2211124720306306
  15. www.sciencedirect.com www.sciencedirect.com
    Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly
    1
    1. scibot 04 Sep 2020
      RRID:AB_2070042

      DOI: 10.1016/j.celrep.2020.03.070

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    sciencedirect.com/science/article/pii/S221112472030396X
  16. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant BtkC481S mutation in B‐cell malignancies
    1
    1. scibot 03 Sep 2020
      RRID:AB_2070042

      DOI: 10.1111/bph.14809

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14809
  17. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 03 Sep 2020
      anti‐rabbit Cleaved Caspase3

      DOI: 10.1111/bph.15149

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15149
  18. www.sciencedirect.com www.sciencedirect.com
    Oxygen Tension and the VHL-Hif1α Pathway Determine Onset of Neuronal Polarization and Cerebellar Germinal Zone Exit
    1
    1. scibot 03 Sep 2020
      RRID:AB_2070042

      DOI: 10.1016/j.neuron.2020.02.025

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    sciencedirect.com/science/article/pii/S0896627320301483
  19. Jan 2020
  20. www.nature.com www.nature.com
    eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma
    1
    1. scibot 13 Jan 2020
      RRID:AB_2070042

      DOI: 10.1038/s41467-019-13086-5

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    nature.com/articles/s41467-019-13086-5
  21. iovs.arvojournals.org iovs.arvojournals.org
    Retinal Pigment Epithelium Cell Death Is Associated With NLRP3 Inflammasome Activation by All-trans Retinal
    1
    1. scibot 13 Jan 2020
      RRID:AB_2070042

      DOI: 10.1167/iovs.18-26360

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    iovs.arvojournals.org/article.aspx
  22. www.sciencedirect.com www.sciencedirect.com
    TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma
    1
    1. scibot 13 Jan 2020
      RRID:AB_2070042

      DOI: 10.1016/j.celrep.2019.12.017

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    sciencedirect.com/science/article/pii/S2211124719316675
  23. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA‐487a‐3p functions as a new tumor suppressor in prostate cancer by targeting CCND1
    1
    1. scibot 13 Jan 2020
      AB_2070042

      DOI: 10.1002/jcp.29078

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    onlinelibrary.wiley.com/doi/10.1002/jcp.29078
  24. www.sciencedirect.com www.sciencedirect.com
    Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism
    1
    1. scibot 13 Jan 2020
      RRID:AB_2070042

      DOI: 10.1016/j.devcel.2019.07.012

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    sciencedirect.com/science/article/pii/S1534580719305842
  25. www.sciencedirect.com www.sciencedirect.com
    p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas
    1
    1. scibot 13 Jan 2020
      RRID:AB_2070042

      DOI: 10.1016/j.celrep.2019.07.027

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    sciencedirect.com/science/article/pii/S2211124719309246
  26. www.cell.com www.cell.com
    LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer’s Disease
    1
    1. scibot 13 Jan 2020
      RRID:AB_2070042

      DOI: 10.1016/j.cell.2019.05.056

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    cell.com/cell/fulltext/S0092-8674(19)30627-0
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional redundancy of HSPA1, HSPA2 and other HSPA proteins in non-small cell lung carcinoma (NSCLC); an implication for NSCLC treatment
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      AB_2070042

      DOI: 10.1038/s41598-019-50840-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC6779912/
  28. www.sciencedirect.com www.sciencedirect.com
    PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism
    1
    1. scibot 13 Jan 2020
      RRID:AB_2070042

      DOI: 10.1016/j.stem.2019.08.017

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    sciencedirect.com/science/article/pii/S1934590919303844
  29. www.sciencedirect.com www.sciencedirect.com
    STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth
    1
    1. scibot 13 Jan 2020
      RRID:AB_2070042

      DOI: 10.1016/j.cmet.2019.10.013

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    sciencedirect.com/science/article/pii/S1550413119306047
  30. www.sciencedirect.com www.sciencedirect.com
    Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1
    1
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      AB_2070042

      DOI: 10.1016/j.chembiol.2019.09.002

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    sciencedirect.com/science/article/pii/S2451945619302764
  31. www.embopress.org www.embopress.org
    A protein quality control pathway regulated by linear ubiquitination
    1
    1. scibot 13 Jan 2020
      RRID:AB_2070042

      DOI: 10.15252/embj.2018100730

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    embopress.org/doi/10.15252/embj.2018100730
  32. www.sciencedirect.com www.sciencedirect.com
    Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier
    1
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      RRID:AB_2070042

      DOI: 10.1016/j.cmet.2019.11.002

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    sciencedirect.com/science/article/pii/S1550413119306096
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    SPARC dependent collagen deposition and gemcitabine delivery in a genetically engineered mouse model of pancreas cancer
    1
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      RRID:AB_2070042

      DOI: 10.1016/j.ebiom.2019.09.024

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    sciencedirect.com/science/article/pii/S2352396419306280
  34. www.mdpi.com www.mdpi.com
    N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil-Targeting FBXW7 Tumor Suppressor
    1
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      RRID:AB_2070042

      DOI: 10.3390/cancers11101456

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    mdpi.com/2072-6694/11/10/1456
  35. www.sciencedirect.com www.sciencedirect.com
    Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet
    1
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      DOI: 10.1016/j.cell.2019.07.048

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    sciencedirect.com/science/article/pii/S0092867419308487
  36. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation
    1
    1. scibot 13 Jan 2020
      RRID:AB_2070042

      DOI: 10.1016/j.neuron.2019.09.003

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    sciencedirect.com/science/article/pii/S0896627319307767
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ral GTPases in Schwann cells promote radial axonal sorting in the peripheral nervous system
    1
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      RRID:AB_2070042

      DOI: 10.1083/jcb.201811150

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    ncbi.nlm.nih.gov/pmc/articles/PMC6605813/
  38. link.springer.com link.springer.com
    Activation of the HIF1α/PFKFB3 stress response pathway in beta cells in type 1 diabetes
    1
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      RRID:AB_2070042

      DOI: 10.1007/s00125-019-05030-5

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    link.springer.com/article/10.1007/s00125-019-05030-5
  39. www.sciencedirect.com www.sciencedirect.com
    miR-29a/b1 Inhibits Hair Follicle Stem Cell Lineage Progression by Spatiotemporally Suppressing WNT and BMP Signaling
    1
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      RRID:AB_2070042

      DOI: 10.1016/j.celrep.2019.10.062

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    sciencedirect.com/science/article/pii/S2211124719313762
  40. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention
    1
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      RRID:AB_2070042

      DOI: 10.1016/j.cmet.2019.12.005

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    sciencedirect.com/science/article/pii/S1550413119306709
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunometabolic Cross-Talk and Regulation of Endocrine and Metabolic Functions: Transgenic overexpression of CTRP3 prevents alcohol-induced hepatic triglyceride accumulation
    1
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    In Vivo Regulation of Oligodendrocyte Precursor Cell Proliferation and Differentiation by the AMPA-Receptor Subunit GluA2
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    The Proton-Coupled Monocarboxylate Transporter Hermes Is Necessary for Autophagy during Cell Death
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    ALDH1 Bio-activates Nifuroxazide to Eradicate ALDHHigh Melanoma-Initiating Cells
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    A Loss of Epigenetic Control Can Promote Cell Death through Reversing the Balance of Pathways in a Signaling Network
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    Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma
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    Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma
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    Altered glutamate clearance in ascorbate deficient mice increases seizure susceptibility and contributes to cognitive impairment in APP/PSEN1 mice
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    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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    Temporal Regulation of the Bacterial Metabolite Deoxycholate during Colonic Repair Is Critical for Crypt Regeneration
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    Gastrodin attenuates microglia activation through renin-angiotensin system and Sirtuin3 pathway
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    Chronic palmitic acid-induced lipotoxicity correlates with defective trafficking of ATP sensitive potassium channels in pancreatic β cells
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    AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity
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    Loss of PRMT5 Promotes PDGFRα Degradation during Oligodendrocyte Differentiation and Myelination
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    Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers
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    Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles
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    Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery
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    Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor
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    Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation
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    Exit from Naive Pluripotency Induces a Transient X Chromosome Inactivation-like State in Males
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    The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression
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    Cell-Specific Imd-NF-κB Responses Enable Simultaneous Antibacterial Immunity and Intestinal Epithelial Cell Shedding upon Bacterial Infection
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    Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis
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    PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis
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    Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma
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    A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution and Cell Polarity during Neurogenesis
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    CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness
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    TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function
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    Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy
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    Combination therapy of lovastatin and AMP‐activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model
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    Mitochondrial Function Regulated by Mitoguardin-1/2 Is Crucial for Ovarian Endocrine Functions and Ovulation
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    LPA1 is a key mediator of intracellular signalling and neuroprotection triggered by tetracyclic antidepressants in hippocampal neurons
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    Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma
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    YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal Mesenchyme
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    A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
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    Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma
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    Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis
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    SOX2 regulates acinar cell development in the salivary gland
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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myofiber-specific TEAD1 overexpression drives satellite cell hyperplasia and counters pathological effects of dystrophin deficiency
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      Cell Signaling 9664S (RRID:AB_2070042

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      AB_2070042

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  125. www.sciencedirect.com www.sciencedirect.com
    Skilled Movements Require Non-apoptotic Bax/Bak Pathway-Mediated Corticospinal Circuit Reorganization
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  126. www.sciencedirect.com www.sciencedirect.com
    IL-22 Upregulates Epithelial Claudin-2 to Drive Diarrhea and Enteric Pathogen Clearance
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  127. www.sciencedirect.com www.sciencedirect.com
    A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis
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  128. academic.oup.com academic.oup.com
    Androgen Stimulates Growth of Mouse Preantral Follicles In Vitro: Interaction With Follicle-Stimulating Hormone and With Growth Factors of the TGFβ Superfamily
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  129. www.sciencedirect.com www.sciencedirect.com
    Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency
    1
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  130. elifesciences.org elifesciences.org
    The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration
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  131. www.sciencedirect.com www.sciencedirect.com
    Transarterial regional hypothermia provides robust neuroprotection in a rat model of permanent middle cerebral artery occlusion with transient collateral hypoperfusion
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  132. www.sciencedirect.com www.sciencedirect.com
    Multivalent Small-Molecule Pan-RAS Inhibitors
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  133. www.sciencedirect.com www.sciencedirect.com
    Angiotensin-II-induced Muscle Wasting is Mediated by 25-Hydroxycholesterol via GSK3β Signaling Pathway
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
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  135. www.sciencedirect.com www.sciencedirect.com
    Tumor necrosis factor-inducible gene 6 protein: A novel neuroprotective factor against inflammation-induced developmental brain injury
    1
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impaired Eukaryotic Translation Initiation Factor 2B Activity Specifically in Oligodendrocytes Reproduces the Pathology of Vanishing White Matter Disease in Mice
    1
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