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Unleashed condensation by recurrent mutations of an epigenetic regulator promotes cancer

1
1. scibot 25 Jun 2026
  
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  RRID:AB_2070987
  
  DOI: 10.64898/2026.02.18.706652
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
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biorxiv.org/content/10.64898/2026.02.18.706652v2
Jun 2025
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CRAMP1 drives linker histone expression to enable Polycomb repression

1
1. scibot 14 Jun 2025
  
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  RRID:AB_2070987
  
  DOI: 10.1016/j.molcel.2025.05.031
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1097276525004708
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Regulation of epigenetics and chromosome structure by human ORC2

1
1. scibot 11 Jun 2025
  
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  RRID:AB_2070987
  
  DOI: 10.1016/j.celrep.2025.115816
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
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  SciCrunch record: RRID:AB_2070987
  
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sciencedirect.com/science/article/pii/S221112472500587X
Aug 2024
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Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS

1
1. scibot 27 Aug 2024
  
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  AB_2070987
  
  DOI: 10.1016/j.neuron.2024.07.025
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0896627324005701
Oct 2023
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The anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment

1
1. scibot 28 Oct 2023
  
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  RRID:AB_2070987
  
  DOI: 10.1016/j.devcel.2023.10.002
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
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sciencedirect.com/science/article/pii/S153458072300521X
Jun 2023
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Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination

1
1. scibot 16 Jun 2023
  
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  RRID:AB_2070987
  
  DOI: 10.1016/j.molcel.2023.05.026
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
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sciencedirect.com/science/article/pii/S1097276523003829
May 2022
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Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging

1
1. scibot 26 May 2022
  
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  RRID:AB_2070987
  
  DOI: 10.1016/j.devcel.2022.05.004
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
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sciencedirect.com/science/article/pii/S153458072200332X
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Nde1 is required for heterochromatin compaction and stability in neocortical neurons

1
1. scibot 19 May 2022
  
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  RRID:AB_2070987
  
  DOI: 10.1016/j.isci.2022.104354
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
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sciencedirect.com/science/article/pii/S2589004222006253
Feb 2022
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Activation-induced chromatin reorganization in neurons depends on HDAC1 activity

1
1. scibot 16 Feb 2022
  
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  RRID:AB_2070987
  
  DOI: 10.1016/j.celrep.2022.110352
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
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  SciCrunch record: RRID:AB_2070987
  
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sciencedirect.com/science/article/pii/S2211124722000687
Jan 2022
www.cell.com www.cell.com

Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors

1
1. scibot 07 Jan 2022
  
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  RRID:AB_2070987
  
  DOI: 10.1016/j.stem.2021.12.002
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2070987
  
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cell.com/cell-stem-cell/fulltext/S1934-5909(21)00486-0
Dec 2021
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Cell adhesion molecule L1 interacts with the chromo shadow domain of heterochromatin protein 1 isoforms α, β, and ɣ via its intracellular domain

1
1. scibot 04 Dec 2021
  
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  RRID:AB_2070987
  
  DOI: 10.1096/fj.202100816R
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100816R
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Evidence of pioneer factor activity of an oncogenic fusion transcription factor

1
1. scibot 17 Aug 2021
  
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  RRID:AB_2070987
  
  DOI: 10.1016/j.isci.2021.102867
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
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  SciCrunch record: RRID:AB_2070987
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8346656/
Jul 2021
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The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation

1
1. scibot 27 Jul 2021
  
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  RRID: 2017/12/2
  
  DOI: 10.1016/j.molcel.2019.10.001
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2070987
  
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  RRIDCUR:Incorrect RRID:AB_2070987
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RRIDCUR:Incorrect

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sciencedirect.com/science/article/pii/S1097276519307610
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Depletion of HP1α alters the mechanical properties of MCF7 nuclei

1
1. scibot 21 Jul 2021
  
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  2616
  
  DOI: 10.1016/j.bpj.2021.05.017
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2070987
  
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  RRIDCUR:Missing RRID:AB_2070987
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RRIDCUR:Missing

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sciencedirect.com/science/article/pii/S000634952100446X
Apr 2021
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Loss of KDM4B exacerbates bone-fat imbalance and mesenchymal stromal cell exhaustion in skeletal aging

1
1. scibot 18 Apr 2021
  
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  RRID:AB_2070987
  
  DOI: 10.1016/j.stem.2021.01.010
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
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  SciCrunch record: RRID:AB_2070987
  
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sciencedirect.com/science/article/pii/S1934590921000102
Sep 2020
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Highly Parallel Quantification and Compartment Localization of Transcription Factors and Nuclear Proteins

1
1. scibot 04 Sep 2020
  
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  RRID:AB_2070987
  
  DOI: 10.1016/j.celrep.2020.01.096
  
  Resource: (Cell Signaling Technology Cat# 2616, RRID:AB_2070987)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2070987
  
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  RRIDCUR:Validated RRID:AB_2070987
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RRID:AB_2070987

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scibot

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sciencedirect.com/science/article/pii/S2211124720301303